Genetic deficiency of lipoprotein lipase causes hyperlipoproteinaemia of following type: (A) Type I (B) Type IIa (C) Type IIb (D) Type V

Genetic deficiency of lipoprotein lipase causes hyperlipoproteinaemia of following type: (A) Type I (B) Type IIa (C) Type IIb (D) Type V
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Chylomicrons are present in fasting blood samples in hyperlipoproteinaemia of following types: (A) Types I and IIa (B) Types IIa and IIb (C) Types I and V (D) Types IV and V

Description : Chylomicrons are present in fasting blood samples in hyperlipoproteinaemia of following types: (A) Types I and IIa (B) Types IIa and IIb (C) Types I and V (D) Types IV and V

Last Answer : Answer : C

Lipoprotein lipase deficiency is associated with: 1) Abetalipoproteinaemia 2) Combined hyperlipidaemia 3) Familial combined hyperlipidaemia 4) Familial Hypercholesterolaemia 5) Marked Hypertriglyceridaemia

Description : Lipoprotein lipase deficiency is associated with: 1) Abetalipoproteinaemia 2) Combined hyperlipidaemia 3) Familial combined hyperlipidaemia 4) Familial Hypercholesterolaemia 5) Marked Hypertriglyceridaemia

Last Answer : Answers-5 Lipoprotein lipase deficiency is autosomal recessive and associated with increased chylomicrons and marked hypertriglyceridaemia.

The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Description : The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Last Answer : Answer : D

An important zinc containing enzyme is (A) Carboxypeptidase A (B) Isocitrate dehydrogenase (C) Cholinesterate (D) Lipoprotein lipase

Description : An important zinc containing enzyme is (A) Carboxypeptidase A (B) Isocitrate dehydrogenase (C) Cholinesterate (D) Lipoprotein lipase

Last Answer : Answer : A

‘Clearing factor’ is (A) Lipoprotein lipase (B) Crotonase (C) 7-dehydro cholesterol (D) β-sitosterol

Description : ‘Clearing factor’ is (A) Lipoprotein lipase (B) Crotonase (C) 7-dehydro cholesterol (D) β-sitosterol

Last Answer : Answer : A

The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase

Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase

Last Answer : Answer : A

A non-functional plasma enzyme is (A) Psudocholinesterase (B) Lipoprotein lipase (C) Proenzyme of blood coagulation (D) Lipase

Description : A non-functional plasma enzyme is (A) Psudocholinesterase (B) Lipoprotein lipase (C) Proenzyme of blood coagulation (D) Lipase

Last Answer : Answer : D

An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase

Description : An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase

Last Answer : Answer : A

Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipase A2 (D) Lipoprotein lipase

Description : Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipase A2 (D) Lipoprotein lipase

Last Answer : Answer : B

This interferes with cholesterol absorption (A) Lipoprotein lipase (B) Creatinase (C) 7-dehydrocholesterol (D) β-sitosterol

Description : This interferes with cholesterol absorption (A) Lipoprotein lipase (B) Creatinase (C) 7-dehydrocholesterol (D) β-sitosterol

Last Answer : Answer : D

The triacyl glycerol present in plasma lipoproteins are hydrolyzed by (A) Linqual lipase (B) Pancreatic lipase (C) Colipase (D) Lipoprotein lipase

Description : The triacyl glycerol present in plasma lipoproteins are hydrolyzed by (A) Linqual lipase (B) Pancreatic lipase (C) Colipase (D) Lipoprotein lipase

Last Answer : Answer : D

Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase

Description : Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase

Last Answer : Answer : C

A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the following? a. Increased glucose uptake and increased glycogen breakdown occur in this circumstance. b. Suppressed activity of lipoprotein lipase results from TNFa c. TNFa stimulates lipolysis d. The differentiation process of pre-adipocytes is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs

Description : A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the ... is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs

Last Answer : Answer: a, b, c, d, e Tumor cachexia appears to be mediated by TNFa. Lipopolysaccharide (LPS), as well as other cytokines, activate a variety of inflammatory cells, most ... chronic syndromes of anorexia, weight loss, and cachexia that are associated with both chronic infection and malignancy

The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level

Description : The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level

Last Answer : C. It increases the incidence of myopathy due to statins

Choose the correct statement(s) about actions of insulin: A. It favours translocation of glucose transporters from intracellular site to the plasma membrane B. It enhances transcription of lipoprotein lipase in vascular endothelium C. It increases production of the enzyme glucokinase D. All of the above

Description : Choose the correct statement(s) about actions of insulin: A. It favours translocation of glucose transporters from intracellular site to the plasma membrane B. It enhances transcription of lipoprotein ... vascular endothelium C. It increases production of the enzyme glucokinase D. All of the above

Last Answer : D. All of the above

Increasing human population put pressure on the natural resources such as land, soil, water, fossil fuels etc. IT causes - I. Soil erosion II. Salinization of soils III. DesertificationIV. Eutrophicationa. I and IIb. I, II and IIIc. III and IVd. I, II, III and IV

Description : Increasing human population put pressure on the natural resources such as land, soil, water, fossil fuels etc. IT causes - I. Soil erosion II. Salinization of soils III. Desertification IV. Eutrophication a. I and II b. I, II and III c. III and IV d. I, II, III and IV

Last Answer : d. I, II, III and IV

(4) Liquid Hydrogen + Liquid Oxygen Explanation: LOX and liquid hydrogen, used in the Space Shuttle orbiter, the Centaur upper stage of the Atlas V, Saturn V upper stages, the newer Delta IV rocket, the H-IIA rocket, and most stages of the European Ariane rockets. Liquid fueled rocicets have higher specific impulse than solid rockets and are capable of being throttled, shut down, and restarted. Only the combustion chamber of a liquid fueled rocket needs to withstand high combustion pressures and temperatures and they can be regeneratively cooled by the liquid propellant.

Description : (4) Liquid Hydrogen + Liquid Oxygen Explanation: LOX and liquid hydrogen, used in the Space Shuttle orbiter, the Centaur upper stage of the Atlas V, Saturn V upper stages, the ... to withstand high combustion pressures and temperatures and they can be regeneratively cooled by the liquid propellant.

Last Answer : The BOD values of water indicate the (1) amount of organic debris (2) amount of oxygen used for biochemical oxidation (3) amount of oxygen used for biochemical reduction (4) amount of ozone used for biochemical oxidation

Genetic engineering requires enzyme: (A) DNA ase (B) Amylase (C) Lipase (D) Restriction endonuclease

Description : Genetic engineering requires enzyme: (A) DNA ase (B) Amylase (C) Lipase (D) Restriction endonuclease

Last Answer : Answer : D

How many men were in the IIA coastal boat crew?

Description : How many men were in the IIA coastal boat crew?

Last Answer : 46

When compared to unfractionated heparin, low molecular weight heparins have (a) Preferential binding affinity to factor Xa relative to Iia (thrombin) (b) Shorter half-lives (c) Dose – dependent renal clearance

Description : When compared to unfractionated heparin, low molecular weight heparins have (a) Preferential binding affinity to factor Xa relative to Iia (thrombin) (b) Shorter half-lives (c) Dose – dependent renal clearance

Last Answer : Ans: A

Unfractionated heparin binds to antithrombin III and inactivates clotting factor(s) (a) Xa (b) Ixa (c) Iia (d) All of the above (e) None of the above

Description : Unfractionated heparin binds to antithrombin III and inactivates clotting factor(s) (a) Xa (b) Ixa (c) Iia (d) All of the above (e) None of the above

Last Answer : Ans: D

If an auditor had a substantial stock investment in a client that s(he) was auditing, which of the following would be true? a. The auditor would lack independence. b. The auditor would be violating the PASB standards. c. The auditor would be violating the Institute of Management Accounting standards d. The auditor would be violating the IIA standards

Description : If an auditor had a substantial stock investment in a client that s(he) was auditing, which of the following would be true? a. The auditor would lack independence. b. The auditor ... be violating the Institute of Management Accounting standards d. The auditor would be violating the IIA standards

Last Answer : The auditor would lack independence

All are true about lesch-nyhan syndrome except (A) Produces self-mutilation (B) Genetic deficiency of the enzyme (C) Elevated levels of uric acid in blood (D) Inheritance is autosomal recessive

Description : All are true about lesch-nyhan syndrome except (A) Produces self-mutilation (B) Genetic deficiency of the enzyme (C) Elevated levels of uric acid in blood (D) Inheritance is autosomal recessive

Last Answer : Answer : B

Trials for gene therapy in human beings were first carried out, with considerable success, in a genetic disease called (A) Cystic fibrosis (B) Thalassemia (C) Adenosine deaminase deficiency (D) Lesch-Nyhan syndrome

Description : Trials for gene therapy in human beings were first carried out, with considerable success, in a genetic disease called (A) Cystic fibrosis (B) Thalassemia (C) Adenosine deaminase deficiency (D) Lesch-Nyhan syndrome

Last Answer : Answer : C

The immediate parent of α, β and γ endorphins is (A) Pro-opiomelanocortin (B) β-lipotropin (C) ATCH (D) Lipoprotein

Description : The immediate parent of α, β and γ endorphins is (A) Pro-opiomelanocortin (B) β-lipotropin (C) ATCH (D) Lipoprotein

Last Answer : Answer : B

Correct ordering of lipoprotein molecules from lowest to the greater density is (A) LDL, IDL, VLDL, chylomicron (B) Chylomicron, VLDL, IDL, LDL (C) VLDL, IDL, LDL, chylomicron (D) LDL, VLDL, IDL, chylomicron

Description : Correct ordering of lipoprotein molecules from lowest to the greater density is (A) LDL, IDL, VLDL, chylomicron (B) Chylomicron, VLDL, IDL, LDL (C) VLDL, IDL, LDL, chylomicron (D) LDL, VLDL, IDL, chylomicron

Last Answer : Answer : B

The major source of extracellular cholesterol for human tissue is (A) Very low density lipoprotein (B) High density lipoprotein (C) Low density lipoprotein (D) Albumin

Description : The major source of extracellular cholesterol for human tissue is (A) Very low density lipoprotein (B) High density lipoprotein (C) Low density lipoprotein (D) Albumin

Last Answer : Answer : C

The compound which has the lowest density is (A) Chylomicron (B) β-Lipoprotein (C) α-Lipoprotein (D) pre β-Lipoprotein

Description : The compound which has the lowest density is (A) Chylomicron (B) β-Lipoprotein (C) α-Lipoprotein (D) pre β-Lipoprotein

Last Answer : Answer : A

The lipoprotein with the fastest electrophoretic mobility and lowest TG content are (A) VLDL (B) LDL (C) HDL (D) Chylomicrones

Description : The lipoprotein with the fastest electrophoretic mobility and lowest TG content are (A) VLDL (B) LDL (C) HDL (D) Chylomicrones

Last Answer : Answer : C

This lipoprotein removes cholesterol from the body (A) HDL (B) VLDL (C) IDL (D) Chylomicrons

Description : This lipoprotein removes cholesterol from the body (A) HDL (B) VLDL (C) IDL (D) Chylomicrons

Last Answer : Answer : A

The first lipoprotein to be secreted by the liver is (A) VLDL (B) nascent VLDL (C) LDL (D) IDL

Description : The first lipoprotein to be secreted by the liver is (A) VLDL (B) nascent VLDL (C) LDL (D) IDL

Last Answer : Answer : B

The β-lipoprotein fraction increases in severe (A) Diabetes Mellitus (B) Uremia (C) Nephritis (D) Muscular dystrophy

Description : The β-lipoprotein fraction increases in severe (A) Diabetes Mellitus (B) Uremia (C) Nephritis (D) Muscular dystrophy

Last Answer : Answer : A

The protein moiety of lipoprotein is known as (A) Apoprotein (B) Pre-protein (C) Post-protein (D) Pseudoprotein

Description : The protein moiety of lipoprotein is known as (A) Apoprotein (B) Pre-protein (C) Post-protein (D) Pseudoprotein

Last Answer : Answer : A

Lipoprotein present in cell membrane is by nature: (A) Hydrophilic (B) Hydrophobic (C) Both (A) and (B) (D) None of these

Description : Lipoprotein present in cell membrane is by nature: (A) Hydrophilic (B) Hydrophobic (C) Both (A) and (B) (D) None of these

Last Answer : Answer : A

Lecithins combine with protein to form (A) Phosphoprotein (B) Mucoprotein (C) Lipoprotein (D) Glycoprotein

Description : Lecithins combine with protein to form (A) Phosphoprotein (B) Mucoprotein (C) Lipoprotein (D) Glycoprotein

Last Answer : Answer : C

The lipoprotein richest in cholesterol is (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Description : The lipoprotein richest in cholesterol is (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Last Answer : Answer : C

Free fatty acids are transported in the blood (A) Combined with albumin (B) Combined with fatty acid binding protein (C) Combined with β -lipoprotein (D) In unbound free salts

Description : Free fatty acids are transported in the blood (A) Combined with albumin (B) Combined with fatty acid binding protein (C) Combined with β -lipoprotein (D) In unbound free salts

Last Answer : Answer : A

A lipoprotein inversely related to the incidence of coronary artherosclerosis is (A) VLDL (B) IDL (C) LDL (D) HDL

Description : A lipoprotein inversely related to the incidence of coronary artherosclerosis is (A) VLDL (B) IDL (C) LDL (D) HDL

Last Answer : Answer : D

A lipoprotein associated with high incidence of coronary atherosclerosis is (A) LDL (B) VLDL (C) IDL (D) HDL

Description : A lipoprotein associated with high incidence of coronary atherosclerosis is (A) LDL (B) VLDL (C) IDL (D) HDL

Last Answer : Answer : A

The apolipoprotein which acts as actiator of extrahepatic lipoprotein is (A) Apo-A (B) Apo-B (C) Apo-C (D) Apo-D

Description : The apolipoprotein which acts as actiator of extrahepatic lipoprotein is (A) Apo-A (B) Apo-B (C) Apo-C (D) Apo-D

Last Answer : Answer : C

The lipoprotein associated with activation of LCAT is (A) HDL (B) LDL (C) VLDL (D) IDL

Description : The lipoprotein associated with activation of LCAT is (A) HDL (B) LDL (C) VLDL (D) IDL

Last Answer : Answer : A

The lipoprotein with the fastest electrophoretic mobility and the lowest triglyceride content is (A) Chylomicron (B) VLDL (C) IDL (D) HDL

Description : The lipoprotein with the fastest electrophoretic mobility and the lowest triglyceride content is (A) Chylomicron (B) VLDL (C) IDL (D) HDL

Last Answer : Answer : D

Carbonic anhydrase is an example of (A) Lipoprotein (B) Phosphoprotein (C) Metalloprotein (D) Chromoprotein

Description : Carbonic anhydrase is an example of (A) Lipoprotein (B) Phosphoprotein (C) Metalloprotein (D) Chromoprotein

Last Answer : Answer : C

Which of the following is a dipeptide? (A) Anserine (B) Glutathione (C) Glucagon (D) β -Lipoprotein

Description : Which of the following is a dipeptide? (A) Anserine (B) Glutathione (C) Glucagon (D) β -Lipoprotein

Last Answer : Answer : A

With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the formation of red blood cell membranes. 3) Chylomicrons are synthesized in the liver. 4) HDL is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.

With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the formation of red blood cell membranes. 3) Chylomicrons are synthesized in the liver. 4) HDL is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.

What is the normal level of lipoprotein (a) ?

Description : What is the normal level of lipoprotein (a) ?

Last Answer : In 40% population, there is no detectable level of Lp(a) in serum. In 20% of population, the Lp(a) concentration in blood is more than 30 mg/dl, and these persons are susceptible to heart attack at a younger age.

What is the significance of lipoprotein (a)?

Description : What is the significance of lipoprotein (a)? 

Last Answer : Lp(a) is associated with heart attacks at the age of 30 or 40 years. Indians have a higher level of Lp(a) than Europeans.

What is lipoprotein(a) ?

Description : What is lipoprotein(a) ?

Last Answer : It is attached to apo B-100 by a disulfide bond. It has significant homology with plasminogen. So it interferes with plasminogen activation and impairs fibrinolysis (Fig.14.10). This leads to unopposed intravascular thrombosis and possible myocardial infarction.