An increase in LDH-5 enzyme is seen in the following except (A) Acute hepatitis (B) Muscular distrophies (C) Breast carcinoma (D) Pulmonary embolism

An increase in LDH-5 enzyme is seen in the following except (A) Acute hepatitis (B) Muscular distrophies (C) Breast carcinoma (D) Pulmonary embolism
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Thrombolytic therapy is indicated in the following conditions except: A. Acute myocardial infarction B. Stroke due to cerebral thrombosis C. Deep vein thrombosis D. Large pulmonary embolism

Description : Thrombolytic therapy is indicated in the following conditions except: A. Acute myocardial infarction B. Stroke due to cerebral thrombosis C. Deep vein thrombosis D. Large pulmonary embolism

Last Answer : B. Stroke due to cerebral thrombosis

On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value? (A) Serum AST (B) Serum CK (C) Serum ALT (D) Serum LDH

Description : On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value? (A) Serum AST (B) Serum CK (C) Serum ALT (D) Serum LDH

Last Answer : Answer : D

On the third day of onset of acute myocardial infarction the enzyme elevated is (A) Serum AST (B) Serum CK (C) Serum LDH (D) Serum ALT

Description : On the third day of onset of acute myocardial infarction the enzyme elevated is (A) Serum AST (B) Serum CK (C) Serum LDH (D) Serum ALT

Last Answer : Answer : C

Which of the following statement(s) is/are true concerning the results of a National Institute of Health Consensus Conference on venous thrombosis and low-dose heparin prophylaxis? a. The odds of developing deep venous thrombosis with low-dose heparin prophylaxis decreases by 67% b. The risk of pulmonary embolism is decreased by almost 50% c. There is no increase in mortality from other causes found in patients treated with low-dose heparin d. There was no difference in the incidence of bleeding complications

Description : Which of the following statement(s) is/are true concerning the results of a National Institute of Health Consensus Conference on venous thrombosis and low-dose heparin prophylaxis? a. The odds of ... treated with low-dose heparin d. There was no difference in the incidence of bleeding complications

Last Answer : Answer: a, b, c In a metaanalysis of 70 randomized trials in 16,000 patients comparing low-dose heparin prophylaxis with standard therapy, the odds of developing deep venous thrombosis ... Similarly, the effectiveness of prophylaxis was not influenced by either two or three times daily dosage

Is Pulmonary Embolism the same as Pulmonary Hypertension?

Description : Is Pulmonary Embolism the same as Pulmonary Hypertension?

Last Answer : A pulmonary embolism is also characterized as central or peripheral, depending on the location or the arterial branch involved. Central vascular zones include the main pulmonary artery, the left and right main ... lobe trunk, the right middle lobe artery, and the right and left lower lobe arteries.

When the patient who has undergone laryngectomy suffers wound breakdown, the nurse monitors him very carefully because he is identified as being at high risk for a) carotid artery hemorrhage. The carotid artery lies close to the stoma and may rupture from erosion if the wound does not heal properly. b) pulmonary embolism. Pulmonary embolism is associated with immobility. c) dehydration. Dehydration may lead to poor wound healing and breakdown. d) pneumonia. Pneumonia is a risk for any postoperative patient.

Description : When the patient who has undergone laryngectomy suffers wound breakdown, the nurse monitors him very carefully because he is identified as being at high risk for a) carotid artery hemorrhage. The ... poor wound healing and breakdown. d) pneumonia. Pneumonia is a risk for any postoperative patient.

Last Answer : a) carotid artery hemorrhage. The carotid artery lies close to the stoma and may rupture from erosion if the wound does not heal properly.

Atropine is contraindicated in: A. Pulmonary embolism B. Digitalis toxicity C. Iridocyclitis D. Raised intraocular tension

Description : Atropine is contraindicated in: A. Pulmonary embolism B. Digitalis toxicity C. Iridocyclitis D. Raised intraocular tension

Last Answer : D. Raised intraocular tension

Atropine is contraindicated in: A. Pulmonary embolism B. Digitalis toxicity C. Iridocyclitis D. Raised intraocular tension

Description : Atropine is contraindicated in: A. Pulmonary embolism B. Digitalis toxicity C. Iridocyclitis D. Raised intraocular tension

Last Answer : D. Raised intraocular tension

Health benefits afforded by the combined estrogenprogestin oral contraceptive pill include the following except: A. Reduced menstrual blood loss B. Lower risk of fibrocystic breast disease C. Lower risk of myocardial infarction D. Lower risk of endometrial carcinoma

Description : Health benefits afforded by the combined estrogenprogestin oral contraceptive pill include the following except: A. Reduced menstrual blood loss B. Lower risk of fibrocystic breast disease C. Lower risk of myocardial infarction D. Lower risk of endometrial carcinoma

Last Answer : . Lower risk of myocardial infarction

Estrogen therapy in postmenopausal women has been implicated in increasing the risk of the following disorders except: A. Gall stones B. Osteoporosis C. Endometrial carcinoma D. Breast cancer

Description : Estrogen therapy in postmenopausal women has been implicated in increasing the risk of the following disorders except: A. Gall stones B. Osteoporosis C. Endometrial carcinoma D. Breast cancer

Last Answer : B. Osteoporosis

The slow moving fraction of LDH is typically increased in pancreas with (A) Cerebrovascular accidents (B) Acute myocardial infarction (C) Acute pancreatitis (D) Acute viral hepatits

Description : The slow moving fraction of LDH is typically increased in pancreas with (A) Cerebrovascular accidents (B) Acute myocardial infarction (C) Acute pancreatitis (D) Acute viral hepatits

Last Answer : Answer : D

Morphine affords symptomatic relief of dyspnoea in acute left ventricular failure by the following mechanisms except: A. Bronchodilatation B. Depression of respiratory centre C. Reduction in cardiac preload D. Shift of blood from pulmonary to systemic circuit

Description : Morphine affords symptomatic relief of dyspnoea in acute left ventricular failure by the following mechanisms except: A. Bronchodilatation B. Depression of respiratory centre C. Reduction in cardiac preload D. Shift of blood from pulmonary to systemic circuit

Last Answer : A. Bronchodilatation

Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Description : Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Last Answer : Answer : D

From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH

Description : From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH

Last Answer : Answer : A

Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these

Description : Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these

Last Answer : Answer : D

Bleomycin is used in most effective drug combination regiment for the chemotherapy of testicular carcinoma. Which one of the following statements about the drug is accurate? (a) Acts mainly in the M phase of the cell cycle (b) Derived from the bark of yew trees (c) Myelosuppression is dose-limiting (d) Peripheral neuropathy occurs in more than 50% of patients (e) Pulmonary infiltrates and fibrosis may occur

Description : Bleomycin is used in most effective drug combination regiment for the chemotherapy of testicular carcinoma. Which one of the following statements about the drug is accurate? (a) Acts mainly in the ... neuropathy occurs in more than 50% of patients (e) Pulmonary infiltrates and fibrosis may occur

Last Answer : Ans: E

Serum gamma glutamyl transpeptidase is raised in (A) Haemolytic jaundice (B) Myocardial infarction (C) Alcoholic hepatitis (D) Acute cholecystitis

Description : Serum gamma glutamyl transpeptidase is raised in (A) Haemolytic jaundice (B) Myocardial infarction (C) Alcoholic hepatitis (D) Acute cholecystitis

Last Answer : Answer : C

Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Description : Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Last Answer : Answer : D

Serum lipase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Infective hepatitis (D) Biliary obstruction

Description : Serum lipase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Infective hepatitis (D) Biliary obstruction

Last Answer : Answer : A

Liver and skeletol measle disorders are characterized by on disk proportionate increase in which of the LDH isoenzyme fraction? (A) LDH-1 (B) LDH-1 and LDH-2 (C) LDH-3 and LDH-4 (D) LDH-2 and LDH-3 (E) LDH-5

Description : Liver and skeletol measle disorders are characterized by on disk proportionate increase in which of the LDH isoenzyme fraction? (A) LDH-1 (B) LDH-1 and LDH-2 (C) LDH-3 and LDH-4 (D) LDH-2 and LDH-3 (E) LDH-5

Last Answer : Answer : C

Tamoxifen citrate is used for palliative treatment of carcinoma breast in: A. Premenopausal women B. Postmenopausal women C. Mastectomized patients D. All of the above

Description : Tamoxifen citrate is used for palliative treatment of carcinoma breast in: A. Premenopausal women B. Postmenopausal women C. Mastectomized patients D. All of the above

Last Answer : D. All of the above

The primary indication of tamoxiphen citrate is: A. Female infertility B. Endometrial carcinoma C. Carcinoma breast D. Endometriosis

Description : The primary indication of tamoxiphen citrate is: A. Female infertility B. Endometrial carcinoma C. Carcinoma breast D. Endometriosis

Last Answer : C. Carcinoma breast

Estrogens are palliative in the following malignancy: A. Carcinoma breast B. Carcinoma cervix C. Endometrial carcinoma D. Carcinoma prostate

Description : Estrogens are palliative in the following malignancy: A. Carcinoma breast B. Carcinoma cervix C. Endometrial carcinoma D. Carcinoma prostate

Last Answer : D. Carcinoma prostate

Select the correct statement about tibolone: A. It is an antiestrogen used for palliative treatment of carcinoma breast B. It is an estrogenic + progestational steroid used for hormone replacement therapy in postmenopausal women C. It is an antiandrogen used for male pattern baldness D. It is a nonsteroidal estrogen used topically for senile vaginitis

Description : Select the correct statement about tibolone: A. It is an antiestrogen used for palliative treatment of carcinoma breast B. It is an estrogenic + progestational steroid used for hormone replacement ... for male pattern baldness D. It is a nonsteroidal estrogen used topically for senile vaginitis

Last Answer : B. It is an estrogenic + progestational steroid used for hormone replacement therapy in postmenopausal women

Biotin deficiency is characterized by the following except (A) Muscular pain (B) Anaemia (C) Nausea (D) Dermatitis

Description : Biotin deficiency is characterized by the following except (A) Muscular pain (B) Anaemia (C) Nausea (D) Dermatitis

Last Answer : Answer : B

Which of the following statements about septic shock are true? A. A circulating myocardial depressant factor may account for the cardiac dysfunction sometimes seen with shock due to sepsis or SIRS. B. A cardiac index (CI) of 6 liters per minute per square meter of body surface, a pulmonary capillary wedge pressure of 15 mm. Hg, and a systemic vascular resistance index (SVRI) of 800 dynes-sec/(cm 5-m 2) is a hemodynamic profile consistent with septic shock. C. An increase in SvO 2 in septic patients may be explained by the finding of anatomic arteriovenous shunts. D. Results of human trials employing antimediator therapy, such as antiendotoxin antibodies, IL-1 receptor antagonist, and tumor necrosis factor (TNF) antibodies, have confirmed animal studies that demonstrate a significant im

Description : Which of the following statements about septic shock are true? A. A circulating myocardial depressant factor may account for the cardiac dysfunction sometimes seen with shock due to sepsis or ... animal studies that demonstrate a significant improvement in survival with the use of such agents.

Last Answer : Answer: AB DISCUSSION: Shock due to sepsis or SIRS frequently manifests as a hyperdynamic cardiovascular response, consisting of an elevated CI and a decreased SVR or SVRI. Occasionally, ... been encouraging thus far in human clinical trials, despite the promising results from many animal studies

Which of the following statement(s) is/are true concerning the effects of MOFS? a. Pulmonary dysfunction tends to arise early and may resolve within 7 to 10 days b. Unless the precipitating insult has prompted oliguric acute tubular necrosis, renal function tends to be maintained early in the course of MOFS c. Although hepatic dysfunction is common with MOFS, the GI tract plays little role in this process d. Intercurrent nosocomial infection, most commonly pulmonary, is a common complication providing a “second hit” to the patient

Description : Which of the following statement(s) is/are true concerning the effects of MOFS? a. Pulmonary dysfunction tends to arise early and may resolve within 7 to 10 days b. Unless the precipitating ... infection, most commonly pulmonary, is a common complication providing a second hit to the patient

Last Answer : Answer: a, b, d Pulmonary dysfunction typically arises early in the development of systemic inflammation and may represent mild relatively localized acute lung injury or it may be a prelude ... is marked by progressive rise in serum bilirubin levels after a latent period of several days

Which of the following statement(s) is/are true concerning the pulmonary response to shock? a. The acute pulmonary vascular response to shock differs markedly from that of systemic vasculature b. The pulmonary edema of ARDS occurs in the face of elevated left heart pressures c. The initial physiologic changes of ARDS involve the capillary endothelial cells and the type I pneumocyte d. Mechanisms proposed in the pathogenesis of ARDS include injury from mediators of inflammation elsewhere and from activated cellular elements e. A decrease in lung compliance may result from the loss of type I pneumocytes

Description : Which of the following statement(s) is/are true concerning the pulmonary response to shock? a. The acute pulmonary vascular response to shock differs markedly from that of systemic vasculature b. The ... elements e. A decrease in lung compliance may result from the loss of type I pneumocytes

Last Answer : Answer: c, d, e Contributing pathophysiologic processes to the pulmonary manifestations of shock include the pulmonary component of the cardiovascular response, disruption of the normal ... injury from mediators of inflammation elaborated elsewhere, and from activated cellular blood elements

Which one of the following characteristics pertains to hepatitis A?a. Transmission is by the fecal-oral route. b. The incubation period is 2 to 4 weeks. c. It is an acute, inflammatory liver disease. d. All of the above (A—C) are correct.

Description : Which one of the following characteristics pertains to hepatitis A? a. Transmission is by the fecal-oral route. b. The incubation period is 2 to 4 weeks. c. It is an acute, inflammatory liver disease. d. All of the above (A—C) are correct.

Last Answer : d. All of the above (A—C) are correct.

A history of infection specifically caused by group A betahemolytic streptococci is associated with which of the following disorders? a) Acute glomerulonephritis Acute glomerulonephritis is also associated with varicella zoster virus, hepatitis B, and Epstein-Barr virus.

Description : A history of infection specifically caused by group A betahemolytic streptococci is associated with which of the following disorders? a) Acute glomerulonephritis Acute glomerulonephritis is ... chronic glomerulonephritis, systemic lupus erythematosus, multiple myeloma, and renal vein thrombosis.

Last Answer : a) Acute glomerulonephritis Acute glomerulonephritis is also associated with varicella zoster virus, hepatitis B, and Epstein-Barr virus.

Respiratory acidosis can occur in all of the following except (A) Pulmonary oedema (B) Hysterical hyperventilation (C) Pneumothorax (D) Emphysema

Description : Respiratory acidosis can occur in all of the following except (A) Pulmonary oedema (B) Hysterical hyperventilation (C) Pneumothorax (D) Emphysema

Last Answer : Answer : B

If results of the serum bilirubin, serum ALP, LDH and AST determinations suggest obstructive jaundice, the best confirmatory test would be the estimation of (A) Serum ALT (B) Serum 5’ nucleotidase (C) Serum Pseudo cholinesterase (D) None of these

Description : If results of the serum bilirubin, serum ALP, LDH and AST determinations suggest obstructive jaundice, the best confirmatory test would be the estimation of (A) Serum ALT (B) Serum 5’ nucleotidase (C) Serum Pseudo cholinesterase (D) None of these

Last Answer : Answer : B

The isoenzymes of LDH (A) Differ only in a single amino acid (B) Differ in catalytic activity (C) Exist in 5 forms depending on M and H monomer contents (D) Occur as monomers

Description : The isoenzymes of LDH (A) Differ only in a single amino acid (B) Differ in catalytic activity (C) Exist in 5 forms depending on M and H monomer contents (D) Occur as monomers

Last Answer : Answer : C

How many different proteins may be present in normal LDH? (A) One (B) Two (C) Three (D) Four

Description : How many different proteins may be present in normal LDH? (A) One (B) Two (C) Three (D) Four

Last Answer : Answer : D

The chemical forces that bind most coenzymes and substrates to enzymes such as LDH are (A) Hydrogen bonds (B) Peptide bonds (C) Coordinate bonds (D) Covalent bonds

Description : The chemical forces that bind most coenzymes and substrates to enzymes such as LDH are (A) Hydrogen bonds (B) Peptide bonds (C) Coordinate bonds (D) Covalent bonds

Last Answer : Answer : D

LDH assays are most useful in diagnosing diseases of the (A) Heart (B) Pancreas (C) Brain (D) Kidney

Description : LDH assays are most useful in diagnosing diseases of the (A) Heart (B) Pancreas (C) Brain (D) Kidney

Last Answer : Answer : A

In which diseases of the following organs, isoenzymes LDH-1 and LDH-2 will be released in plasma? (A) Kidney, R.B.C and Liver (B) Heart, Kidney and R.B.C (C) Heart, Kidney and Liver (D) Heart, Lungs and Brain

Description : In which diseases of the following organs, isoenzymes LDH-1 and LDH-2 will be released in plasma? (A) Kidney, R.B.C and Liver (B) Heart, Kidney and R.B.C (C) Heart, Kidney and Liver (D) Heart, Lungs and Brain

Last Answer : Answer : B

Patients with hepatocellular jaundice, as compared to those with purely obstructive jaundice tend to have (A) Lower serum ALP, LDH and AST activity (B) Lower serum ALP, Higher LDH and AST activity (C) Higher serum ALP, LDH and AST activity (D) Higher serum ALP, Lower LDH and AST activity

Description : Patients with hepatocellular jaundice, as compared to those with purely obstructive jaundice tend to have (A) Lower serum ALP, LDH and AST activity (B) Lower serum ALP, Higher LDH and AST activity (C) Higher serum ALP, LDH and AST activity (D) Higher serum ALP, Lower LDH and AST activity

Last Answer : Answer : B

In early stages of myocardial ischemia the most sensitive indicator is the measurement of the activity of (A) CPK (B) SGPT (C) SGOT (D) LDH

Description : In early stages of myocardial ischemia the most sensitive indicator is the measurement of the activity of (A) CPK (B) SGPT (C) SGOT (D) LDH

Last Answer : Answer : A

Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C) Increased serum alkaline phosphatase and decreased levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT

Last Answer : Answer : D

What is the advantage of CK estimation over LDH estimation to identify myocardial infarction?

Description : What is the advantage of CK estimation over LDH estimation to identify myocardial infarction?

Last Answer : The CK level starts to rise within three hours of infarction. Therefore, CK estimation is very useful to detect early cases, where ECG changes may be ambiguous. The CK level is not increased in hemolysis or in congestive cardiac failure; and therefore CK has an advantage over LDH.

LDH level in blood is increased in which conditions?

Description : LDH level in blood is increased in which conditions?

Last Answer : Myocardial infarction, hemolytic anemias, muscular dystrophy, carcinomas, leukemias, and any condition which causes necrosis of body cells.

How do you separate LDH iso-enzymes in laboratory?

Description : How do you separate LDH iso-enzymes in laboratory?

Last Answer : By cellulose acetate electrophoresis at pH 8.6.

Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase

Description : Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase

Last Answer : Answer : B

Acute hemolytic anemia in person’s sensitive to the Fava beans is due to the deficiency of the enzyme: (A) Pyruvate dehydrogenase (B) G-6-PD (C) Aconitase (D) Transketolase

Description : Acute hemolytic anemia in person’s sensitive to the Fava beans is due to the deficiency of the enzyme: (A) Pyruvate dehydrogenase (B) G-6-PD (C) Aconitase (D) Transketolase

Last Answer : Answer : B

In acute pancreatitis, the enzyme raised in first five days is (A) Serum amylase (B) Serum lactic dehydrogenase (C) Urinary lipase (D) Urinary amylase

Description : In acute pancreatitis, the enzyme raised in first five days is (A) Serum amylase (B) Serum lactic dehydrogenase (C) Urinary lipase (D) Urinary amylase

Last Answer : Answer : A

When the female patient demonstrates thickening, scaling, and erosion of the nipple and areola, the nurse recognizes that the patient is exhibiting signs of a) Paget’s disease. Paget’s disease is a malignancy of mammary ducts with early signs of erythema of nipple and areola. b) acute mastitis. Acute mastitis is demonstrated by nipple cracks or abrasions along with reddened and warm breast skin and tenderness.

Description : When the female patient demonstrates thickening, scaling, and erosion of the nipple and areola, the nurse recognizes that the patient is exhibiting signs of a) Paget's disease. Paget's disease ... the breast and demonstrates an orange peel apearance of breast skin with enlargement of skin pores.

Last Answer : a) Paget’s disease. Paget’s disease is a malignancy of mammary ducts with early signs of erythema of nipple and areola.

Oral contraceptive use increases the risk of occurrence of the following diseases except: A. Hypertension B. Leg vein thrombosis C. Endometrial carcinoma D. Gall stones

Description : Oral contraceptive use increases the risk of occurrence of the following diseases except: A. Hypertension B. Leg vein thrombosis C. Endometrial carcinoma D. Gall stones

Last Answer : C. Endometrial carcinoma

Which of the following statements accurately describes cancer of the esophagus? a) Chronic irritation of the esophagus is a known risk factor. In the United States, cancer of the esophagus has been associated with the ingestion of alcohol and the use of tobacco. b) It is three times more common in women in the U.S. than men. In the United States, carcinoma of the esophagus occurs more than three times as often in men as in women. c) It is seen more frequently in Caucasians than in African Americans. It is seen more frequently in African Americans than in Caucasians. d) It usually occurs in the fourth decade of life. It usually occurs in the fifth decade of life.

Description : Which of the following statements accurately describes cancer of the esophagus? a) Chronic irritation of the esophagus is a known risk factor. In the United States, cancer of the esophagus has been associated ... occurs in the fourth decade of life. It usually occurs in the fifth decade of life.

Last Answer : a) Chronic irritation of the esophagus is a known risk factor. In the United States, cancer of the esophagus has been associated with the ingestion of alcohol and the use of tobacco.