Description : Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT
Last Answer : Answer : D
Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT
Description : Creatine phosphokinase isoenzyme is a marker for (A) Kidney disease (B) Liver disease (C) Myocardial infarction (D) None of these
Last Answer : Answer : C
Description : In which diseases of the following organs, isoenzymes LDH-1 and LDH-2 will be released in plasma? (A) Kidney, R.B.C and Liver (B) Heart, Kidney and R.B.C (C) Heart, Kidney and Liver (D) Heart, Lungs and Brain
Last Answer : Answer : B
Description : The slow moving fraction of LDH is typically increased in pancreas with (A) Cerebrovascular accidents (B) Acute myocardial infarction (C) Acute pancreatitis (D) Acute viral hepatits
Description : An increase in LDH-5 enzyme is seen in the following except (A) Acute hepatitis (B) Muscular distrophies (C) Breast carcinoma (D) Pulmonary embolism
Description : The abnormal isoenzyme need not (A) Be an oxidoreductase (B) Have any coenzyme (C) Require ATP (D) Be localized intracellularly (E) Be a catalyst
Last Answer : Answer : A
Description : Which of the following connective tissue disorders is characterized by insoluble collagen being formed and accumulating excessively in the tissues? a) Scleroderma Scleroderma occurs initially in the ... In polymyalgia rheumatic, immunoglobulin is deposited in the walls of inflamed temporal arteries.
Last Answer : a) Scleroderma Scleroderma occurs initially in the skin but also occurs in blood vessels, major organs, and body systems, potentially resulting in death.
Description : Atopic allergic disorders are characterized by a) a hereditary predisposition. Atopic allergic disorders are characterized by a hereditary predisposition and production of a local reaction to IgE ... of a local reaction to IgE antibodies produced in response to common environmental allergens.
Last Answer : a) a hereditary predisposition. Atopic allergic disorders are characterized by a hereditary predisposition and production of a local reaction to IgE antibodies produced in response to common environmental allergens.
Description : Which of the following disorders is characterized by a group of symptoms produced by an excess of free circulating cortisol from the adrenal cortex? a) Cushing's syndrome The patient ... individual with Hashimoto's disease demonstrates inflammation of the thyroid gland, resulting in hypothyroidism.
Last Answer : a) Cushing’s syndrome The patient with Cushing’s syndrome demonstrates truncal obesity, moon face, acne, abdominal striae, and hypertension.
Description : An organic substance bound to an enzyme and essential for the activity of enzyme is called (A) Holoenzyme (B) Apoenzyme (C) Coenzyme (D) Isoenzyme
Description : Which of the following isoenzyme of lactate dehydrogenase is raised in serum in myocardial infarction: (A) LD1 (B) LD2 (C) LD1 and LD2 (D) LD5
Description : Tarui disease is characterized by the deficiency of the enzyme: (A) Liver phosphorylase (B) Muscle phosphorylase (C) Muscle and erythrocyte phosphofructokinase (D) Lysosomal acid maltase
Description : Her’s disease is characterized by deficiency of (A) Muscle phosphorylase (B) Liver phosphorylase (C) Debranching enzyme (D) Glycogen synthase
Description : Mc Ardle’s syndrome is characterized by the absence of (A) Liver phosphorylase (B) Muscle phosphorylase (C) Branching enzyme (D) Debranching enzyme
Description : Von Gierke’s disease is characterized by the deficiency of (A) Glucose-6-phosphatase (B) α -1→ 4 Glucosidase (C) 1→ 6 Glucosidase (D) Liver phosphorylase
Description : Fucosidosis is characterized by (A) Muscle spasticity (B) Liver enlargement (C) Skin rash (D) Kidney failure
Description : If results of the serum bilirubin, serum ALP, LDH and AST determinations suggest obstructive jaundice, the best confirmatory test would be the estimation of (A) Serum ALT (B) Serum 5’ nucleotidase (C) Serum Pseudo cholinesterase (D) None of these
Description : The isoenzymes of LDH (A) Differ only in a single amino acid (B) Differ in catalytic activity (C) Exist in 5 forms depending on M and H monomer contents (D) Occur as monomers
Description : When the increase in one product is directly proportionate to increase the other product is called
Last Answer : Ans. Complementary Production
Description : Which of the following statement(s) is/are true concerning the autoregulation necessary to maintain oxygen consumption and oxygen delivery? a. A change in oxygen consumption is followed by a proportionate ... increase in cardiac output d. The normal ratio of oxygen delivery to consumption is 2:1
Last Answer : Answer: a The relationships between oxygen consumption and oxygen delivery represent one of the most interesting regulation systems in homeostasis. First of all, if one of the three components ... in oxygen consumption. The normal ratio of oxygen delivery to consumption is approximately 5:1
Description : The Psychological law of consumption states that - (1) proportionate increase in consumption is less than proportionate increase in income (2) increase in income is equal to increase in consumption (3) ... is greater than increase in income (4) consumption does not change with a change in income
Last Answer : (1) proportionate increase in consumption is less than proportionate increase in income Explanation: According to Keynes' psychological law of consumption, increased aggregate consumption due to increased ... demand of the people are already fulfilled, they start saving the extra additional income.
Description : A goods can be considered a normal goods in economics if increase in disposal income of the consumer causes (a) An increase in demand ; (b) No change in demand ; (c) Decrease in demand ; (d) Less than proportionate change in demand
Last Answer : (a) An increase in demand ;
Description : A goods can be considered inferior goods in economics if increase in disposal income of the consumer causes (a) An increase in demand ; (b) No change in demand ; (c) Decrease in demand ; (d) Less than proportionate change in demand
Last Answer : ; (c) Decrease in demand ;
Description : The Psychological law of consumption states that (1) proportionate increase in consumption is less than proportionate increase in income (2) increase in income is equal to increase in consumption (3) ... is greater than increase in income (4) consumption does not change with a change in income
Last Answer : proportionate increase in consumption is less than proportionate increase in income
Description : How many different proteins may be present in normal LDH? (A) One (B) Two (C) Three (D) Four
Description : The chemical forces that bind most coenzymes and substrates to enzymes such as LDH are (A) Hydrogen bonds (B) Peptide bonds (C) Coordinate bonds (D) Covalent bonds
Description : LDH assays are most useful in diagnosing diseases of the (A) Heart (B) Pancreas (C) Brain (D) Kidney
Description : On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value? (A) Serum AST (B) Serum CK (C) Serum ALT (D) Serum LDH
Description : Patients with hepatocellular jaundice, as compared to those with purely obstructive jaundice tend to have (A) Lower serum ALP, LDH and AST activity (B) Lower serum ALP, Higher LDH and AST activity (C) Higher serum ALP, LDH and AST activity (D) Higher serum ALP, Lower LDH and AST activity
Description : From the following myocardial infarction, the earliest serum enzyme to rise is (A) Creatine Kinase (B) GOT (C) GPT (D) LDH
Description : Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these
Description : On the third day of onset of acute myocardial infarction the enzyme elevated is (A) Serum AST (B) Serum CK (C) Serum LDH (D) Serum ALT
Description : In early stages of myocardial ischemia the most sensitive indicator is the measurement of the activity of (A) CPK (B) SGPT (C) SGOT (D) LDH
Description : What is the advantage of CK estimation over LDH estimation to identify myocardial infarction?
Last Answer : The CK level starts to rise within three hours of infarction. Therefore, CK estimation is very useful to detect early cases, where ECG changes may be ambiguous. The CK level is not increased in hemolysis or in congestive cardiac failure; and therefore CK has an advantage over LDH.
Description : LDH level in blood is increased in which conditions?
Last Answer : Myocardial infarction, hemolytic anemias, muscular dystrophy, carcinomas, leukemias, and any condition which causes necrosis of body cells.
Description : How do you separate LDH iso-enzymes in laboratory?
Last Answer : By cellulose acetate electrophoresis at pH 8.6.
Description : Immunodeficiency: a) A localized protective reaction of tissue to irritation, injury, or infection, characterized by pain, redness, swelling, and sometimes a loss of function b) A disorder or deficiency ... effect and damage the liver. e) It is an immunity disorder which is genetically transferred.
Last Answer : Ans: B
Description : The distinctive feature of the isoenzyme cyclooxygenase-2 is (a) It is not inhibited by indomethacin (b) It is inducible (c) It generates cytoprotective prostagladins in gastric mucosa (d) It is found only in foetal tissues
Description : Protein part of enzyme is know as – (1) Isoenzyme (2) Holoenzyme (3) Apoenzyme (4) All the above
Last Answer : (3) Apoenzyme Explanation: Enzymes are defined as biological catalysts. Chemically all enzymes are globular proteins. Each enzyme catalyses only one chemical reaction. Protein part of enzyme is known as Apoenzyme.
Description : The term ‘humulin’ is used for (a) hydrolytic enzyme (b) powerful antibiotic (c) human insulin (d) isoenzyme.
Last Answer : (c) human insulin
Description : Select the antibiotic which inhibits drug metabolizing isoenzyme CYP3A4 resulting in potentially fatal drug interaction with terfenadine: A. Erythromycin B. Clindamycin C. Gentamicin D. Vancomycin
Last Answer : A. Erythromycin
Description : The following is not true of the cytochrome P450 isoenzyme CYP2D6: A. It generates the hepatotoxic metabolite N-acetyl benzoquinone immine from paracetamol B. It is involved in demethylation of ... for poor capacity to hydroxylate many drugs including metoprolol D. It is inhibited by quinidine
Last Answer : A. It generates the hepatotoxic metabolite N-acetyl benzoquinone immine from paracetamol
Description : The isoenzyme cyclooxygenase-2 (COX-2) is expressed constitutively at the following site: A. Gastric mucosa B. Neutrophils C. Blood platelets D. Juxtaglomerular apparatus
Last Answer : D. Juxtaglomerular apparatus
Description : The distinctive feature of the isoenzyme cyclooxygenase-2 is: A. It is not inhibited by indomethacin B. It is inducible C. It generates cytoprotective prostagladins in gastric mucosa D. It is found only in foetal tissues
Last Answer : B. It is inducible
Description : Select the antihistaminic which blocks cardiac K+ channels when given in high doses or along with drugs that inhibit CYP3A4 isoenzyme: A. Chlorpheniramine B. Promethazine C. Astemizole D. Loratadine
Last Answer : C. Astemizole
Last Answer : A. It generates the hepatotoxic metabolite N-acetyl benzoquinone immine from paracetamo
Description : Protein part of enzyme is know as (1) Isoenzyme (2) Holoenzyme (3) Apoenzyme (4) All the above
Last Answer : Apoenzyme
Description : Alzheimer’s disease in human beings is characterized by the degeneration of ---- A. Kidney cells B. Nerve cells (Answer) C. Liver cells D. Spleen cells
Last Answer : B. Nerve cells (Answer)
Description : AE in young chicks is characterized by A A. nervous disorder B. watery diarrhea C. lesions on the liver D. None of these
Last Answer : nervous disorder