Description : Serum inorganic phosphorous decreases in all the following conditions except (A) Hyperparathyroidism (B) Intestinal malabsorption (C) Osteomalacia (D) Chronic renal failure
Last Answer : Answer : D
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) is decreased in (A) Rickets (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Renal failure
Last Answer : Answer : A
Description : Levels of serum calcium and inorganic phosphorus are increased in (A) Hypervitaminosis D (B) Hypoparathyroidism (C) Hypovitaminosis D (D) None of these
Description : Which of the following conditions is an indication for the use of calcitonin? (a) Chronic renal failure (b) Hypoparathyroidism (c) Intestinal osteodystrophy (d) Pager’s disease (e) Rickets
Last Answer : Ans: D
Description : Serum sodium level rises in all of the following except (A) Renal failure (B) Prolonged steroid therapy (C) Aldosteronism (D) Dehydration
Description : In hypoparathyroidism (A) Plasma calcium and inorganic phosphorous are low (B) Plasma calcium and inorganic phosphorous are high (C) Plasma calcium is low and inorganic phosphorous high (D) Plasma calcium is high and inorganic phosphorous low
Last Answer : Answer : C
Description : Primary hyperparathyroidism may occur in association with the following conditions 1) Chronic renal failure 2) Vitamin D deficiency 3) Gastrinoma 4) Autoimmune polyendocrine syndrome 5) Sjogren's syndrome
Last Answer : Answers-3 The association of primary hyperparathyroidism and a gastrinoma would suggest a diagnosis of multiple endocrine neoplasia type 1. CRF causes secondary or tertiary hyperparathyroidism, with vit D deficiency causing secondary hyperparathyroidism. Ther is no association with Sjogren's.
Description : The normal serum inorganic phosphorous level is (A) 1.5–2.5 mg/100 ml (B) 2.5–4.5 mg/100 ml (C) 4.5–6.5 mg/100 ml (D) 0.5–1.5 mg/100 ml
Last Answer : Answer : B
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) in children is about (A) 30 (B) 40 (C) 50 (D) 60
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) in adults is about (A) 30 (B) 40 (C) 50 (D) 60
Description : The correct statement about serum inorganic phosphorous concentration is (A) It is higher in men than in women (B) It is higher in women than in men (C) It is higher in adults than in children (D) It is higher in children than in adults
Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase
Description : An increase in carbohydrate metabolism is accompanied by temporary decrease in serum: (A) Calcium (B) Phosphate (C) Iron (D) Sodium
Description : Altering the amino acid profile in total parenteral nutrition solutions can be of benefit in certain conditions. Which of the following conditions are associated with a benefit by supplementation with the ... c. Short gut syndrome and glutamine d. Chronic renal failure and essential amino acids
Last Answer : Answer: a, c In a number of conditions, altering the amino acid profile of the total parenteral nutrition solution can be of benefit. TPN with amino acids of high biologic value ... Glutamine-enriched TPN partially attenuates villous atrophy and may be useful in treatment of short gut syndrome
Description : The following conditions give rise to red blood cells with increased mean cell volume: a. anaemia of chronic disease. b. pernicious anaemia. c. anaemia due to renal failure. d. haemolytic anaemi
Last Answer : pernicious anaemia.
Description : After operative removal of the parathyroid glands resulting into hypoparathyroidism the concentration of the serum calcium may drop below (A) 11 mg (B) 10 mg (C) 9 mg (D) 7 mg
Description : Glucagon secretion increases (A) After a carbohydrate-rich meal (B) After a fat-rich meal (C) When blood glucose is high (D) When blood glucose is low
Description : Glucokinase (A) Is widely distributed and occurs in most mammalian tissues (B) Has a high km for glucose and hence is important in the phosphorylation of glucose primarily after ingestion of a carbohydrate rich meal (C) Is widely distributed in Prokaryotes (D) None of these
Last Answer : B
Description : A decrease in serum sodium may occur in (A) Adrenocortical insufficiency (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Thyrotoxicosis
Description : Serum potassium level decreases in (A) Familial periodic paralysis (B) Addison’s disease (C) Renal failure (D) All of these
Description : Serum biochemistry of a 60 year old man revealed calcium of 1.98 mmol/l and phosphate of 0.55 mmol/l with an alkaline phosphatase of 450 IU/l.Which among the following mosts suits ... biochemistry? 1) Osteoporosis 2) Osteomalacia 3) Pagets Disease 4) Secondary Hyperparathyroidism 5) Renal failure
Last Answer : Answers-2 Osteomalacia is associated with low calcium and phosphate with raised alkaline phosphatase. Serum biochemistry is normal in osteoporosis. Pagets disease is associated with normal ... renal failure when tertiary hyperparathyroidism sets in there is low calcium with raised phosphate.
Description : Hyponatraemia occurs in the following condition: (A) Addison’s disease (B) Chronic renal failure (C) Severe diarrhoea (D) All of these
Description : A 60-year-old man was diagnosed last year with adenocarcinoma of the lung, and a 4 cm mass lesion was treated with a right lower lobectomy. He now has an ... 2) Membranous glomerulonephritis 3) Minimal change glomerulonephritis 4) Nodular glomerulosclerosis 5) Rapidly progressive glomerulonephritis
Last Answer : Answers-2 Most cases of membranous GN are idiopathic, but in some patients there is a history of an infection or a malignancy (usually lung) with antigenemia.
Description : A 59-year-old trauma patient has suffered multiple septic complications including severe pneumonia, intraabdominal abscess, and major wound infection. He has now developed signs of multisystem organ ... the same extent d. In patients with hepatic failure, carbohydrate load should be increased
Last Answer : Answer: a, b The most severe complication of sepsis is multiple system organ dysfunction syndrome, which may result in death. The development of organ failure requires changes in the ... should be provided as fat emulsion. If encephalopathy develops, protein load should also be reduced0
Description : A number of changes in trace mineral metabolism are noted during sepsis. Which of the following change(s) may be observed in a septic or trauma patient? a. Plasma iron levels are noted to ... are noted to decrease c. Plasma serum zinc levels may decrease d. Administration of iron is appropriate
Last Answer : Answer: a, c Changes in the balance of magnesium, inorganic phosphate, zinc, and potassium generally follow alterations in nitrogen balance. Although the iron-binding capacity of transferrin ... concentrations can be ascribed almost entirely to the levels of the ceruloplasmin produced by the liver
Description : Clinical uses of Vitamin D do not include (a) Chronic renal failure (b) Hyperparathyroidism (c) Intestinal osteodystrophy (d) Nutritional rickets (e) Osteoporosis
Last Answer : Ans: B
Description : The term used to describe total urine output of less than 400 mL in 24 hours is a) oliguria. Oliguria is associated with acute and chronic renal failure. b) anuria. Anuria is used to ... Nocturia refers to awakening at night to urinate. d) dysuria. Dysuria refers to painful or difficult urination.
Last Answer : a) oliguria. Oliguria is associated with acute and chronic renal failure.
Description : Radiopaque lesions are seen in: A. Multiple myeloma B. Paget’s disease C. Hyperparathyroidism D. Chronic renal failure
Last Answer : B. Paget’s disease
Description : A patient of chronic renal failure maintained on intermittent haemodialysis has anaemia not responding to iron therapy. Which of the following additional drug is indicated: A. Epoetin B. Cyanocobalamin C. Folic acid D. Pyridoxine
Last Answer : A. Epoetin
Description : Recombinant human erythropoietin is indicated for: A. Megaloblastic anaemia B. Haemolytic anaemia C. Anaemia in patients of thalassemia D. Anaemia in chronic renal failure patients
Last Answer : D. Anaemia in chronic renal failure patients
Description : Hypercalcaemia can occur in all the following except (A) Hyperparathyroidism (B) Hypervitaminosis D (C) Milk alkali syndrome (D) Nephrotic syndrome
Description : Inborn errors of urea cycle can cause all the following except (A) Vomiting (B) Ataxia (C) Renal failure (D) Mental retardation
Description : A high concentration of PTH in blood causes (A) Increase in plasma calcium and inorganic phosphorous (B) Decrease in plasma calcium and inorganic phosphorous (C) Increase in plasma calcium ... in plasma inorganic phosphorous (D) Decrease in plasma calcium and increase in plasma inorganic phosphorous
Description : When ATP forms AMP (A) Inorganic pyrophosphate is produced (B) Inorganic phosphorous is produced (C) Phsophagen is produced (D) No energy is produced
Description : Which of the following concerning the pH of urine is correct? 1) is a useful indicator of the acid/base balance of the blood 2) rises on a vegetarian diet 3) is determined by the concentration of ... lower than 5.5 in renal tubular acidosis 5) would be above 7.0 after prolonged and severe vomiting
Last Answer : Answers-2 c - excretion of ammonium occurs when an acid urine is produced but the pH of urine is of course determined by the concentration of H+ ions d-unable to lower the pH to ... and distal nephron and this perpetuates the metabolic alkalosis until the fluid balance is restored with IV fluids.
Description : Renal ricket is caused by renal tubular defect (usually inherited) which interferes with reabsorption of (A) Calcium (B) Phosphorous (C) Sodium (D) Chloride
Description : The characteristic of hyperparathyroidism is (A) Low serum calcium (B) High serum phosphorous (C) Low serum calcium and high serum phosphorous (D) High serum calcium and low serum phosphate
Description : The normal serum level of phosphorous in children varies from (A) 1–2 mg/100 ml (B) 2–3 mg/100 ml (C) 3–4 mg/100 ml (D) 4–7 mg/100 ml
Description : A 15-year-old girl was seen by her family physician because of increasing lethargy. She had a recent history of the "flu". Biochemistry tests show that she has renal impairement. ... will likely develop a restrictive lung disease 5) She will probably improve with additional corticosteroid therapy
Last Answer : Answers-2 The findings point to focal segmental glomerulosclerosis (FSGS), which leads to chronic renal failure in half of cases. The lack of resolution with corticosteroid therapy and the progression to chronic renal failure is what sets FSGS apart from minimal change disease.
Description : Which of the following serum enzyme rises in myocardial infarction: (A) Creatine kinase (B) GOT (C) LDH (D) All of these
Description : Serum lactate dehydrogenase rises in (A) Viral hepatitis (B) Myocardial infarction (C) Carcinomatosis (D) All of these
Description : Which of the following hormones is not involved in carbohydrate metabolism? (A) ACTH (B) Glucagon (C) Vasopressin (D) Growth hormone
Description : The building up and breaking down of protoplasm are concerned with the metabolism of (A) Carbohydrate (B) Lipid (C) Protein (D) Minerals
Description : The metabolism of protein is integrated with that of carbohydrate and fat through (A) Oxaloacetate (B) Citrate (C) Isocitrate (D) Malate
Description : Compared to the resting state, vigorously contracting muscle shows (A) An increased conversion of pyruvate to lactate (B) Decreased oxidation of pyruvate of CO2 and water (C) A decreased NADH/NAD+ ratio (D) Decreased concentration of AMP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 21
Last Answer : A
Description : Which of the following hormones is not involved in carbohydrate metabolism? (A) Cortisol (B) ACTH (C) Glucogen (D) Vasopressin
Last Answer : D
Description : An essential for converting Glucose to Glycogen in Liver is (A) Lactic acid (B) GTP (C) CTP (D) UTP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 19
Description : The formation of citrate from oxalo acetate and acetyl CoA is (A) Oxidation (B) Reduction (C) Condensation (D) Hydrolysis CARBOHYDRATES AND CARBOHYDRATE METABOLISM 17
Last Answer : C
Description : Dihydroxyacetone phosphate and glyceraldehyde-3-phosphate are intercoverted by CARBOHYDRATES AND CARBOHYDRATE METABOLISM 13 (A) Triose isomerase (B) Phosphotriose isomerase (C) Diphosphotriose isomerase (D) Dihydroxyacetone phosphorylase
Description : In the diet of a diabetic patient, the recommended carbohydrate intake should preferably be in the form of CARBOHYDRATES AND CARBOHYDRATE METABOLISM 11 (A) Monosaccharides (B) Dissaccharides (C) Polysaccharides (D) All of these