The hormone which acts through intracellular receptor protein is

The hormone which acts through intracellular receptor protein is
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The hormone which acts through intracellular receptor protein is A. Growth hormone B. Prolactin C. Thyroxine D. Adrenaline
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The following are true about parathyroid hormone a. it is an 84 amino acid peptide hormone b. it increases calcium absorption from the gastrointestinal tract c. it acts on a cell surface receptor that increases intracellular cyclic AMP d. all above

Description : The following are true about parathyroid hormone a. it is an 84 amino acid peptide hormone b. it increases calcium absorption from the gastrointestinal tract c. it acts on a cell surface receptor that increases intracellular cyclic AMP d. all above

Last Answer : all above

Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of the following statement(s) is/are true concerning intracellular receptors? a. The messengers or hormones must by lipophilic b. These intracellular receptors generally regulate protein synthesis c. The intracellular receptors are located entirely in the nucleus of the cell d. A heat-shock protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor

Description : Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of ... protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor

Last Answer : Answer: a, d Although most hormone and other messenger receptors are extracellular, intracellular receptors have been identified. The hormone messengers involved for these receptors are primarily ... DNA-binding domain of the receptor. Activation involves the dissociation of the inhibitor protein

Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the G-protein involve binding and hydrolysis of ATP c. The G protein receptor generates an intracellular messenger commonly through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors

Description : Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the ... through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors

Last Answer : Answer: a, c All water-soluble regulatory molecules bind to the cell surface receptor proteins. Binding of the appropriate ligand evokes an intracellular signal which usually regulates ... are adenylate cyclase, which converts ATP to cAMP, and the polyphosphoinositide-specific phospholipase C

Hormone that binds to intracellular receptor is (A) Adrenocorticotropic hormone (B) Thyroxine (C) Follicle stimulating hormone (D) Glucagon

Description : Hormone that binds to intracellular receptor is (A) Adrenocorticotropic hormone (B) Thyroxine (C) Follicle stimulating hormone (D) Glucagon

Last Answer : Answer : B

The following receptor type has 7 helical membrane spanning amino acid segments with 3 extracellular and 3 intracellular loops: A. Tyrosine protein kinase receptor B. Gene expression regulating receptor C. Intrinsic ion channel containing receptor D. G protein coupled receptor

Description : Receptors perform the following function/functions: A. Ligand recognition B. Signal transduction C. Both ligand recognition and signal transduction D. Disposal of agonists and antagonists

Last Answer : D. Disposal of agonists and antagonists

The following receptor type has 7 helical membrane spanning amino acid segments with 3 extracellular and 3 intracellular loops: A. Tyrosine protein kinase receptor B. Gene expression regulating receptor C. Intrinsic ion channel containing receptor D. G protein coupled receptor

Description : The following receptor type has 7 helical membrane spanning amino acid segments with 3 extracellular and 3 intracellular loops: A. Tyrosine protein kinase receptor B. Gene expression regulating receptor C. Intrinsic ion channel containing receptor D. G protein coupled receptor

Last Answer : D. G protein coupled receptor

6.2 Which hormone acts through a cytoplasmic receptor: A. Calcitriol B. Prolactin C. Vasopressin D. None of the abov

Description : 6.2 Which hormone acts through a cytoplasmic receptor: A. Calcitriol B. Prolactin C. Vasopressin D. None of the abov

Last Answer : A.Calcitol binds to cytoplasmic membrane and enhances the absorption of Calcium by increasing the calcium binding proteins-calbindin-D proteins.

The GABAB receptor: A. Is an intrinsic ion channel containing receptor B. Mediates neuronal depolarization C. Is insensitive to blockade by bicuculline D. Regulates intracellular cAMP

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Last Answer : C. Is insensitive to blockade by bicuculline

All of the following subserve as intracellular second messengers in receptor mediated signal transduction except: A. Cyclic AMP B. Inositol trisphosphate C. Diacyl glycerols D. G proteins

Description : All of the following subserve as intracellular second messengers in receptor mediated signal transduction except: A. Cyclic AMP B. Inositol trisphosphate C. Diacyl glycerols D. G proteins

Last Answer : D. G proteins

All of the following subserve as intracellular second messengers in receptor mediated signal transduction except: A. Cyclic AMP B. Inositol trisphosphate C. Diacyl glycerols D. G proteins

Description : All of the following subserve as intracellular second messengers in receptor mediated signal transduction except: A. Cyclic AMP B. Inositol trisphosphate C. Diacyl glycerols D. G proteins

Last Answer : D. G proteins

Phosphorylated IRS-1 activates GRB-2 which is (A) G-protein receptor binding protein-2 (B) Growth factor receptor binding protein-2 (C) Growth hormone receptor binding protein-2 (D) Glucocorticoid receptor binding protein-2 226 MCQs IN BIOCHEMISTRY

Description : Phosphorylated IRS-1 activates GRB-2 which is (A) G-protein receptor binding protein-2 (B) Growth factor receptor binding protein-2 (C) Growth hormone receptor binding protein-2 (D) Glucocorticoid receptor binding protein-2 226 MCQs IN BIOCHEMISTRY

Last Answer : Answer : B

The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin

Description : The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin

Last Answer : Answer : D

Identify A, B and C in the diagramatic representation of the mechanism of hormone action. B A Response 1 C Physiological Responses Select the correct option from the following. (a) A-Steroid Hormone; B-Hormone-receptor Complex; C-Protein (b) A-Protein Hormone; B-Receptor; C-Cyclic AMP (c) A-Steroid Hormone; B-Receptor; C - Second Messenger (d) A-Protein Hormone; B-Cyclic AMP; C-Hormone-receptor Complex

Description : Identify A, B and C in the diagramatic representation of the mechanism of hormone action. B A Response 1 C Physiological Responses Select the correct option from the following. (a) A-Steroid Hormone; B- ... ; C - Second Messenger (d) A-Protein Hormone; B-Cyclic AMP; C-Hormone-receptor Complex

Last Answer : (b) A-Protein Hormone; B-Receptor; C-Cyclic AMP

Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the cytoplasm. C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.

Description : Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the ... activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.

Last Answer : C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes.

Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane

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Last Answer : C) production of new proteins

Select the opioid analgesic which acts primarily through κ (kappa) opioid receptor: A. Pentazocine B. Methadone C. Buprenorphine D. Pethidine

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Last Answer : A. Pentazocine

As an antitubercular drug, isoniazid has the following advantages except: A. It is tuberculocidal B. It acts on both extra and intracellular bacilli C. Tubercle bacilli do not develop resistance against it D. It is cheap

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Last Answer : C. Tubercle bacilli do not develop resistance against it

An example of protein which acts as a hormone is : (1) nypsin (2) Oxytocin (3) Keratin (4) Casein

Description : An example of protein which acts as a hormone is : (1) nypsin (2) Oxytocin (3) Keratin (4) Casein

Last Answer : (2) Oxytocin Explanation: Hormonal Proteins are messenger proteins which help to coordinate certain bodily activities. Examples include Insulin, Oxytocin, and Somatotropin. Oxytocin stimulates contractions in females during childbirth.

An example of protein which acts as a hormone is : (1) Trypsin (2) Oxytocin (3) Keratin (4) Casein

Description : An example of protein which acts as a hormone is : (1) Trypsin (2) Oxytocin (3) Keratin (4) Casein

Last Answer : Oxytocin

Second messengers a. are substances that interact with first messengers inside cells b. are substances that bind to first messengers in the cell membrane c. are hormones secreted by cells in response to stimulation by another hormone d. mediate the intracellular responses to many different hormonesand neurotransmitters e. are not formed in the brain

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Last Answer : mediate the intracellular responses to many different hormonesand neurotransmitters

Intracellular organelles involved with protein synthesis include: a. Mitochondria b. Endoplasmic reticulum c. Golgi complex d. Lysosomes

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The best understood intracellular messenger is cyclic AMP (cAMP). Which of the following statement(s) concerning this intracellular messenger is/are correct? a. Intracellular cyclic AMP is constantly degraded by a specific enzyme, cAMP phosphodiesterase b. Most of the actions of cAMP are mediated by activation of protein kinase A c. Intracellular levels of cAMP are relatively stable and change solely in response to activation of adenylate cyclase d. cAMP is the only cyclic nucleotide active as an intracellular messenger

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Compared with intracellular fluid, extracellular fluid has, a. a greater osmolarity b. a higher protein concentration c. a lower chloride ion concentration d. a lower hydrogen ion concentration

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Last Answer : a lower hydrogen ion concentration

Which of the following structure-function pairs is mismatched? (A) Lysosome-intracellular digestion (B) Golgi body-secretion of cell products (C) Ribosome-protein synthesis (D) Glyoxysome-detoxification

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Last Answer : (D) Glyoxysome-detoxification

Apolipoprotien B-100 acts as (A) Enzyme activator (B) Ligand for receptor (C) Both (A) and (B) (D) None of these

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Last Answer : Answer : B

Apolipoprotein A-I acts as (A) Enzyme activator (B) Ligand for receptor (C) Both (A) and (B) (D) None of these

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The apolipoprotein which acts as ligand for LDL receptor is (A) B-48 (B) B-100 (C) A (D) C

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Cell regulation can be thought of as the effector side of cell communication. Most commonly cell regulation occurs by means of extracellular chemical messengers. Which of the following statement(s) is/are true concerning these messengers? a. Paracrine regulation involves a messenger which is produced and acts systemically b. The extracellular signal or stimulus is received by a receptor on or in the target cell c. Neurocrine regulation depends on a physical connection between the neuron and the target cell d. Most hormones, local mediators, and neurotransmitters readily cross the cell plasma membrane

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Aliskiren acts by (A) inhibiting the conversion of Angiotensin I to II (B) inhibiting the release of rennin (C) inhibiting the binding of Angiotensin II to the receptor (D) inhibiting the action of aldosterone

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Last Answer : (B) inhibiting the release of rennin

Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia

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Last Answer : C. Mediates low ceiling respiratory depression

Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above

Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above

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Hormone which regulate gene expression or chromosome by interation of hormone receptor complex with the genome are

Description : Hormone which regulate gene expression or chromosome by interation of hormone receptor complex with the genome are

Last Answer : Hormone which regulate gene expression or chromosome by interation of hormone receptor complex with the genome are

`Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as

Description : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as

Last Answer : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as

Binding of growth hormone to its receptor results in increased transcription of (A) c-fos gene (B) c-myc gene (C) p-53 gene (D) None of these

Description : Binding of growth hormone to its receptor results in increased transcription of (A) c-fos gene (B) c-myc gene (C) p-53 gene (D) None of these

Last Answer : Answer : A

Binding of growth hormone to its receptor results in phosphorylation of (A) JAK-2 (B) Growth hormone receptor (C) STATs (D) All of these

Description : Binding of growth hormone to its receptor results in phosphorylation of (A) JAK-2 (B) Growth hormone receptor (C) STATs (D) All of these

Last Answer : Answer : D

Hormone that bind to cell surface receptor and require the second messenger camp is (A) Antidiuretic hormone (B) Cholecystokinin (C) Calcitriol (D) Gastrin

Description : Hormone that bind to cell surface receptor and require the second messenger camp is (A) Antidiuretic hormone (B) Cholecystokinin (C) Calcitriol (D) Gastrin

Last Answer : Answer : A

G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins

Description : G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins

Last Answer : are activated by the binding of an extracellular ligand to a membrane receptor

According to the accepted concept of hormone action, if receptor molecules are removed from target organs, then the target organ will (a) continue to respond to the hormone without any difference (b) not respond to the hormone (c) continue to respond to the hormone but will require higher concentration (d) continue to respond to the hormone but in the opposite way.

Description : According to the accepted concept of hormone action, if receptor molecules are removed from target organs, then the target organ will (a) continue to respond to the hormone without any difference ( ... require higher concentration (d) continue to respond to the hormone but in the opposite way.

Last Answer : (b) not respond to the hormone

Which of the following is NOT correct about hormones? A) Hormones are generally found across the animal kingdom. B) Hormones may be used at a distance from where the hormone is made. C) Hormones have a slower effect than that mediated by the nervous system. D) Hormones bind to receptor sites at a target cell. E) Hormones are directed to the target organ and avoid contact with non-target cells.

Description : Which of the following is NOT correct about hormones? A) Hormones are generally found across the animal kingdom. B) Hormones may be used at a distance from where the hormone is made. C) ... target cell. E) Hormones are directed to the target organ and avoid contact with non-target cells.

Last Answer : E) Hormones are directed to the target organ and avoid contact with non-target cells.

Which statement is NOT true about steroid hormones? A) They include hormones such as estrogen. B) They do not bind to cell surface receptors. C) The hormone-receptor complex can enter the nucleus. D) The hormone-receptor complex can bind to chromatin. E) Steroid hormones act faster than non-steroid (peptide) hormones.

Description : Which statement is NOT true about steroid hormones? A) They include hormones such as estrogen. B) They do not bind to cell surface receptors. C) The hormone-receptor complex can enter the ... complex can bind to chromatin. E) Steroid hormones act faster than non-steroid (peptide) hormones.

Last Answer : E) Steroid hormones act faster than non-steroid (peptide) hormones.

The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor

Description : The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor

Last Answer : Answer : B

All the following statements about epidermal growth factor are true except (A) It is a protein (B) It possess quaternary structure (C) Its receptor is made up of a single polypeptide chain (D) Its receptor possesses tyrosine kinase domain

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Last Answer : Answer : B

Vitamin A is required for the formation of a light receptor protein known as (A) Globulin (B) Lypoprotein (C) Chomoprotein (D) Rhodospin

Description : Vitamin A is required for the formation of a light receptor protein known as (A) Globulin (B) Lypoprotein (C) Chomoprotein (D) Rhodospin

Last Answer : Answer : D

A _____ is a protein receptor on the surface of macrophages, dendritic cells, and endothelial cells that allow them to recognize foreign cell markers. a. Toll-like receptor (TLR) b. pathogen-associated c. Membrane attack complex (MAC) d. Natural killer cells (NK)

Description : A _____ is a protein receptor on the surface of macrophages, dendritic cells, and endothelial cells that allow them to recognize foreign cell markers. a. Toll-like receptor (TLR) b. pathogen-associated c. Membrane attack complex (MAC) d. Natural killer cells (NK)

Last Answer : b. pathogen-associated

The insulin receptor is a: A. Ion channel regulating receptor B. Tyrosine protein kinase receptor C. G-protein coupled receptor D. None of the above

Description : The insulin receptor is a: A. Ion channel regulating receptor B. Tyrosine protein kinase receptor C. G-protein coupled receptor D. None of the above

Last Answer : B. Tyrosine protein kinase receptor

Which of the following is a G protein coupled receptor: A. Muscarinic cholinergic receptor B. Nicotinic cholinergic receptor C. Glucocorticoid receptor D. Insulin receptor

Description : Which of the following is a G protein coupled receptor: A. Muscarinic cholinergic receptor B. Nicotinic cholinergic receptor C. Glucocorticoid receptor D. Insulin receptor

Last Answer : A. Muscarinic cholinergic receptor

Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Last Answer : C. Alter its folding or alignment of subunits

The following 5-HT receptor is not a G protein coupled receptor: A. 5-HT1 B. 5-HT2 C. 5-HT3 D. 5-HT4

Description : The following 5-HT receptor is not a G protein coupled receptor: A. 5-HT1 B. 5-HT2 C. 5-HT3 D. 5-HT4

Last Answer : C. 5-HT3

The receptor transduction mechanism with the fastest time-course of response effectuation is: A. Adenylyl cyclase-cyclic AMP pathway B. Phospholipase C-IP3: DAG pathway C. Intrinsic ion channel operation D. Protein synthesis modulation

Description : The receptor transduction mechanism with the fastest time-course of response effectuation is: A. Adenylyl cyclase-cyclic AMP pathway B. Phospholipase C-IP3: DAG pathway C. Intrinsic ion channel operation D. Protein synthesis modulation

Last Answer : C. Intrinsic ion channel operation

Which of the following is a G protein coupled receptor: A. Muscarinic cholinergic receptor B. Nicotinic cholinergic receptor C. Glucocorticoid receptor D. Insulin receptor

Description : Which of the following is a G protein coupled receptor: A. Muscarinic cholinergic receptor B. Nicotinic cholinergic receptor C. Glucocorticoid receptor D. Insulin receptor

Last Answer : A. Muscarinic cholinergic receptor