Amino acid sequence of the encoded protein is not changed in (A) Silent mutation (B) Acceptable mis-sense mutation (C) Both (A) and (B) (D) None of these

Amino acid sequence of the encoded protein is not changed in (A) Silent mutation (B) Acceptable mis-sense mutation (C) Both (A) and (B) (D) None of these
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If the codon UAC on mRNA changes into UAG as a result of a base substitution in DNA, it will result in (A) Silent mutation (B) Acceptable mis-sense mutation (C) Nonsense mutation (D) Frameshift mutation

Description : If the codon UAC on mRNA changes into UAG as a result of a base substitution in DNA, it will result in (A) Silent mutation (B) Acceptable mis-sense mutation (C) Nonsense mutation (D) Frameshift mutation

Last Answer : Answer : C

Haemoglobin S is an example of a/an (A) Silent mutation (B) Acceptable mis-sense mutation (C) Unacceptable mis-sense mutation (D) Partially acceptable mis-sense mutation

Description : Haemoglobin S is an example of a/an (A) Silent mutation (B) Acceptable mis-sense mutation (C) Unacceptable mis-sense mutation (D) Partially acceptable mis-sense mutation

Last Answer : Answer : D

Substitution of a base can result in a (A) Silent mutation (B) Mis-sense mutation (C) Nonsense mutation(D) All of these

Description : Substitution of a base can result in a (A) Silent mutation (B) Mis-sense mutation (C) Nonsense mutation(D) All of these

Last Answer : Answer : D

The effect of a mis-sense mutation can be (A) Acceptable (B) Partially acceptable (C) Unacceptable (D) All of these

Description : The effect of a mis-sense mutation can be (A) Acceptable (B) Partially acceptable (C) Unacceptable (D) All of these

Last Answer : Answer : D

Insertion of a base in a gene can cause (A) Change in reading frame (B) Garbled amino acid sequence in the encoded protein (C) Premature termination of translation (D) All of these

Description : Insertion of a base in a gene can cause (A) Change in reading frame (B) Garbled amino acid sequence in the encoded protein (C) Premature termination of translation (D) All of these

Last Answer : Answer : D

A silent mutation is most likely to result from (A) Substitution of the first base of a codon (B) Substitution of the third base of a codon (C) Conversion of a nonsense codon into a sense codon (D) Conversion of a sense codon into a nonsense codon

Description : A silent mutation is most likely to result from (A) Substitution of the first base of a codon (B) Substitution of the third base of a codon (C) Conversion of a nonsense codon into a sense codon (D) Conversion of a sense codon into a nonsense codon

Last Answer : Answer : B

In the following partial sequence of mRNA, a mutation of the template DNA results in a change in codon 91 to UAA. The type of mutation is 88 89 90 91 92 93 94 GUC GAC CAG UAG GGC UAA CCG (A) Missene (B) Silent (C) Nonsense (D) Frame shit

Description : In the following partial sequence of mRNA, a mutation of the template DNA results in a change in codon 91 to UAA. The type of mutation is 88 89 90 91 92 93 94 GUC GAC CAG UAG GGC UAA CCG (A) Missene (B) Silent (C) Nonsense (D) Frame shit

Last Answer : Answer : B

What type of mutation results in the formation of a protein with one incorrect amino acid?

Description : What type of mutation results in the formation of a protein with one incorrect amino acid?

Last Answer : What is the answer ?

The half-life of a protein depends upon its (A) Signal sequence (B) N-terminus amino acid (C) C-terminus amino acid (D) Prosthetic group

Description : The half-life of a protein depends upon its (A) Signal sequence (B) N-terminus amino acid (C) C-terminus amino acid (D) Prosthetic group

Last Answer : Answer : B

Edman’s reaction can be used to (A) Determine the number of tyrosine residues in a protein (B) Determine the number of aromatic amino acid residues in a protein (C) Determine the amino acid sequence of a protein (D) Hydrolyse the peptide bonds in a protein

Description : Edman’s reaction can be used to (A) Determine the number of tyrosine residues in a protein (B) Determine the number of aromatic amino acid residues in a protein (C) Determine the amino acid sequence of a protein (D) Hydrolyse the peptide bonds in a protein

Last Answer : Answer : C

Amino acid sequence directs protein folding?

Description : Insulin possesses two polypeptide chains denoted A and B that are linked by disulfide bonds. Upon denaturation by reduction of the SH groups of insulin, followed by reoxidation, only 7% of the ... can these data be reconciled with the hypothesis that the amino acid sequence directs protein folding?

Last Answer : Insulin is synthesized as preproinsulin that is proteolytically processed in the β cells of the islets of Langerhans in the pancreas, to give proinsulin. After synthesis and folding, a section of the ... lacking the C peptide, lacks some of the information necessary to direct the folding process. 

The enzymes encoded by z, y and a genes of lac operon are inducible, and their inducer is (A) Lactose (B) Allo-lactose (C) Catabolite gene activator protein (D) All of these

Description : The enzymes encoded by z, y and a genes of lac operon are inducible, and their inducer is (A) Lactose (B) Allo-lactose (C) Catabolite gene activator protein (D) All of these

Last Answer : Answer : B

Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- Restriction endonuclease can cleave ss and dsDNA both C- Restriction fragment length polymorphism (RFLP) is usually formed in coding sequenceof a gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Description : Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- Restriction endonuclease can cleave ss and dsDNA both C- Restriction ... sequenceof a gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Last Answer : Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction fragment length polymorphism (RFLP) is usually formed in coding sequence of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Description : Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction ... of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Last Answer : Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction fragment length polymorphism (RFLP) is usually formed in coding sequence of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Description : Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction ... of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Last Answer : Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.

Description : Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.

Last Answer : (b) tRNA

.Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.

Description : .Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.

Last Answer : (c) mRNA

The primary structure of a protein refers to : (a) whether the protein is fibrous or globular (b) the amino acid sequence in the polypeptide chain (c) the orientation of the amino acid side chains in space (d) the presence or absence of an α-helix

Description : The primary structure of a protein refers to : (a) whether the protein is fibrous or globular (b) the amino acid sequence in the polypeptide chain (c) the orientation of the amino acid side chains in space (d) the presence or absence of an α-helix

Last Answer : the amino acid sequence in the polypeptide chain

Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Last Answer : C. Alter its folding or alignment of subunits

Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Last Answer : C. Alter its folding or alignment of subunits

In the encoded file, which type of changes are made in sysmbols ? a. They are compressed b. They are changed to a letter or symbol c. They are represented in the graphical form d. No changes are made

Description : In the encoded file, which type of changes are made in sysmbols ? a. They are compressed b. They are changed to a letter or symbol c. They are represented in the graphical form d. No changes are made

Last Answer : d. No changes are made

Which of the following statement(s) is/are true concerning DNA? a. DNA is contained only in the nucleus of the cell b. DNA strands are encoded by the sequence of four bases—adenine, guanine, cytosine and uridine c. The basic unit of information of DNA is the intron, a sequence of three bases d. There are an infinite number of possible codons

Description : Which of the following statement(s) is/are true concerning DNA? a. DNA is contained only in the nucleus of the cell b. DNA strands are encoded by the sequence of four bases-adenine, guanine, cytosine ... DNA is the intron, a sequence of three bases d. There are an infinite number of possible codons

Last Answer : Answer: a The genetic blueprint of an organism is carried in the nucleus of every cell, encoded by the sequence of four bases-adenine, guanine, cytosine and thymine, which together make up ... codons. Sixty-one of these code for amino acids and three are termination signals called stop codons

Thalassemia is an example of – (1) Deletion mutation (2) Point mutation (3) Silent mutation (4) Frame shift mutation

Description : Thalassemia is an example of – (1) Deletion mutation (2) Point mutation (3) Silent mutation (4) Frame shift mutation

Last Answer : (4) Frame shift mutation Explanation: Frame shift mutations are associated with Thalassemia. They involve a deletion or insertion of one' or two base pairs within a coding sequence of a gene. As ... and deletions, the reading frame of mRNA is altered resulting in a nonsense sequence of amino acids.

Thalassemia is an example of (1) Deletion mutation (2) Point mutation (3) Silent mutation (4) Frame shift mutation

Description : Thalassemia is an example of (1) Deletion mutation (2) Point mutation (3) Silent mutation (4) Frame shift mutation

Last Answer : Frame shift mutation

The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is (a) Decreased permeability into the bacterial cell (b) Acquisition of a plasmid encoded for chloramphenicol acetyl transferase (c) Lowered affinity of the bacterial ribosome for chloramphenicol (d) Switching over from ribosomal to mitochondrial protein synthesis

Description : The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is (a) Decreased permeability into the bacterial cell (b) Acquisition of a plasmid encoded ... bacterial ribosome for chloramphenicol (d) Switching over from ribosomal to mitochondrial protein synthesis

Last Answer : Ans: B

The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is: A. Decreased permeability into the bacterial cell B. Acquisition of a plasmid encoded for chloramphenicol acetyl transferase C. Lowered affinity of the bacterial ribosome for chloramphenicol D. Switching over from ribosomal to mitochondrial protein synthesi

Description : The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is: A. Decreased permeability into the bacterial cell B. Acquisition of a plasmid encoded ... the bacterial ribosome for chloramphenicol D. Switching over from ribosomal to mitochondrial protein synthesi

Last Answer : B. Acquisition of a plasmid encoded for chloramphenicol acetyl transferas

The activity of mammalian L-amino acid oxidase, an FMN – flavo protein, is quite (A) Slow (B) Rapid (C) Both (A) and (B) (D) None of these

Description : The activity of mammalian L-amino acid oxidase, an FMN – flavo protein, is quite (A) Slow (B) Rapid (C) Both (A) and (B) (D) None of these

Last Answer : Answer : A

The sequence of amino acid in which the biological value of parathormone is (A) 1–15 (B) 1–34 (C) 30–50 (D) 50–84

Description : The sequence of amino acid in which the biological value of parathormone is (A) 1–15 (B) 1–34 (C) 30–50 (D) 50–84

Last Answer : Answer : B

Different isoenzymes of an enzyme have the same (A) Amino acid sequence (B) Michaelis constant (C) Catalytic activity (D) All of these

Description : Different isoenzymes of an enzyme have the same (A) Amino acid sequence (B) Michaelis constant (C) Catalytic activity (D) All of these

Last Answer : Answer : C

Pre-proinsulin contains a signal sequence having (A) 9 amino acid residues (B) 19 amino acid residues (C) 27 amino acid residues (D) 33 amino acid residues

Description : Pre-proinsulin contains a signal sequence having (A) 9 amino acid residues (B) 19 amino acid residues (C) 27 amino acid residues (D) 33 amino acid residues

Last Answer : Answer : B

The primary structure of a protein refers to the sequence of amino acids that are linked together in a long chain. Which of the following common items would best represent the primary structure of a protein?

Description : The primary structure of a protein refers to the sequence of amino acids that are linked together in a long chain. Which of the following common items would best represent the primary structure of a protein?

Last Answer : beads of different colors joined together on a piece of string

What Portion of DNA which carries the genetic code for the formation of a particular protein by specifying its amino acids sequence?

Description : What Portion of DNA which carries the genetic code for the formation of a particular protein by specifying its amino acids sequence?

Last Answer : Gene

Which of the following is the “quaternary structure” of proteins concerned with? (a) sequence of amino acids in the peptide chain (b) description of the way the peptide chains are arranged with respect to each other (c) location of the disulfide bridges in the peptide chain (d) conformation of the protein backbone

Description : Which of the following is the quaternary structure of proteins concerned with? (a) sequence of amino acids in the peptide chain (b) description of the way the peptide chains are arranged with ... (c) location of the disulfide bridges in the peptide chain (d) conformation of the protein backbone

Last Answer : description of the way the peptide chains are arranged with respect to each other

The _______ structure of a protein is the sequence of amino acids. a. primary b. secondary c. tertiary d. quaternary

Description : The _______ structure of a protein is the sequence of amino acids. a. primary b. secondary c. tertiary d. quaternary

Last Answer : a. primary

How many high-energy phosphate bond equivalents are required for amino acid activation in protein synthesis? (A) One (B) Two (C) Three (D) Four

Description : How many high-energy phosphate bond equivalents are required for amino acid activation in protein synthesis? (A) One (B) Two (C) Three (D) Four

Last Answer : Answer : B

In E. coli the chain initiating amino acid in protein synthesis is (A) N-formyl methionine(B) Methionine (C) Serine (D) Cysteine

Description : In E. coli the chain initiating amino acid in protein synthesis is (A) N-formyl methionine(B) Methionine (C) Serine (D) Cysteine

Last Answer : Answer : A

Nonsense codons bring about (A) Amino acid activation (B) Initiation of protein synthesis (C) Termination of protein synthesis (D) Elongation of polypeptide chains

Description : Nonsense codons bring about (A) Amino acid activation (B) Initiation of protein synthesis (C) Termination of protein synthesis (D) Elongation of polypeptide chains

Last Answer : Answer : C

Initiation of protein synthesis begins with binding of (A) 40S ribosomal unit on mRNA (B) 60S ribosomal unit (C) Charging of tRNA with specific amino acid (D) Attachment of aminoacyl tRNA on mRNA

Description : Initiation of protein synthesis begins with binding of (A) 40S ribosomal unit on mRNA (B) 60S ribosomal unit (C) Charging of tRNA with specific amino acid (D) Attachment of aminoacyl tRNA on mRNA

Last Answer : Answer : A

A non essential amino acid is not (A) Absorbed in the intestines (B) Required in the diet (C) Incorporated into the protein (D) Metabolized by the body

Description : A non essential amino acid is not (A) Absorbed in the intestines (B) Required in the diet (C) Incorporated into the protein (D) Metabolized by the body

Last Answer : Answer : B

One of the given example is an amino acid: (A) Oh-Lysine (B) Protein (C) Leucine (D) Serine

Description : One of the given example is an amino acid: (A) Oh-Lysine (B) Protein (C) Leucine (D) Serine

Last Answer : Answer : B

The greatest buffering capacity at physiologic pH would be provided by a protein rich in which of the following amino acids ? (A) Lysine (B) Histidine (C) Aspartic acid (D) Valine

Description : The greatest buffering capacity at physiologic pH would be provided by a protein rich in which of the following amino acids ? (A) Lysine (B) Histidine (C) Aspartic acid (D) Valine

Last Answer : Answer : B

Non-Protein amino acids are (A) Ornithine (B) β-alanine (C) γ-amino butyric acid (D) All of these

Description : Non-Protein amino acids are (A) Ornithine (B) β-alanine (C) γ-amino butyric acid (D) All of these

Last Answer : Answer : A

The end product of protein digestion in G.I.T. is (A) Dipeptide (B) Tripeptide (C) Polypeptide (D) Amino acid

Description : The end product of protein digestion in G.I.T. is (A) Dipeptide (B) Tripeptide (C) Polypeptide (D) Amino acid

Last Answer : Answer : D

The amino acid from which synthesis of the protein of hair keratin takes place is (A) Alanine (B) Methionine (C) Proline (D) Hydroxyproline

Description : The amino acid from which synthesis of the protein of hair keratin takes place is (A) Alanine (B) Methionine (C) Proline (D) Hydroxyproline

Last Answer : Answer : B

What are the reagents that are used for identify- ing the first amino acid in a protein?

Description : What are the reagents that are used for identify- ing the first amino acid in a protein?

Last Answer : Fluoro dinitro benzene, dansyl chloride, phenyl iso thio cyanate.

Which amino acid is synthesised after it gets in- corporated into the protein?

Description : Which amino acid is synthesised after it gets in- corporated into the protein?

Last Answer : Hydroxyproline

.If the DNA codons are ATG ATG ATG and a cytosine base is inserted at the beginning, then which of the following will result? (a) CAT GAT GAT G (b) A non-sense mutation (c) C ATG ATG ATG (d) CA TGA TGA TG

Description : .If the DNA codons are ATG ATG ATG and a cytosine base is inserted at the beginning, then which of the following will result? (a) CAT GAT GAT G (b) A non-sense mutation (c) C ATG ATG ATG (d) CA TGA TGA TG

Last Answer : (a) CAT GAT GAT G

.If the DNA codons are ATG ATG ATG and a cytosine base is inserted at the beginning, then which of the following will result? (a) CAT GAT GAT G (b) A non-sense mutation (c) C ATG ATG ATG (d) CA TGA TGA TG

Description : .If the DNA codons are ATG ATG ATG and a cytosine base is inserted at the beginning, then which of the following will result? (a) CAT GAT GAT G (b) A non-sense mutation (c) C ATG ATG ATG (d) CA TGA TGA TG

Last Answer : (a) CAT GAT GAT G

All the following statements about protooncogenes are true except (A) They are present in human beings (B) They are present in healthy cells (C) Proteins encoded by them are essential (D) They are expressed only when a healthy cell has been transformed into a cancer cell

Description : All the following statements about protooncogenes are true except (A) They are present in human beings (B) They are present in healthy cells (C) Proteins encoded by them are essential (D) They are expressed only when a healthy cell has been transformed into a cancer cell

Last Answer : Answer : D