Description : Retinoblastoma can result from a mutation in (A) ras proto-oncogene (B) erbB proto-oncogene (C) p 53 gene (D) RB 1 gene
Last Answer : Answer : D
Description : Ras proto-oncogene encodes (A) Epidermal growth factor (EGF) (B) Receptor for EGF (C) Signal transducer for EGF (D) Nuclear transcription factor
Last Answer : Answer : C
Description : RB 1 gene is (A) A tumour suppressor gene (B) Oncogene (C) Proto-oncogene (D) Activated proto-oncogene
Last Answer : Answer : A
Description : P 53 gene: (A) A proto-oncogene (B) An oncogene (C) A tumour suppressor gene (D) None of these
Description : Enhancer elements have all the following features except (A) They increase gene expression through a promoter (B) Each enhancer activates a specific promoter (C) They may be located far away from the promoter (D) They may be upstream or downstream from the promoter
Last Answer : Answer : B
Description : All of the following statements about eukaryotic promoters are true except (A) They may be located upstream or down stream from the structural gene (B) They have two consensus sequences ( ... (D) Mutations in promoter region can decrease the efficiency of transcription of the structural gene
Description : Cancer cells may become resistant to amethopterin by (A) Developing mechanisms to destroy amethopterin (B) Amplification of dihydrofolate reducatse gene (C) Mutation in the dihydrofolate reductase ... is no longer inhibited by amethopterin (D) Developing alternate pathway of thymidylate synthesis
Description : The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein
Last Answer : .is located immediately upstream of the start codon
Description : The rivosome binding site A- forms a sltem- loop structure in the RNA B- is located upstream of the promoter sequence C- is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein
Last Answer : is located immediately upstream of the start codon
Description : A point mutation results from (A) Substitution of a base (B) Insertion of a base (C) Deletion of a base (D) All of these
Description : The oncogene theory states that transforming genes a. Normally Occur In The Host Genome. b. Can Exist In Viruses. c. Are Not Of Viral Origin. d. All Of The Above (A—C) Are Correct.
Last Answer : d. All Of The Above (A—C) Are Correct
Description : Inheritance of skin colour in humans is an example of (a) point mutation (b) polygenic inheritance (c) codominance (d) chromosomal aberration.
Last Answer : (b) polygenic inheritance
Description : The most likely lethal mutation is (A) Substitution of adenine for cytosine (B) Insertion of one nucleotide (C) Deletion of three nucleotides (D) Substitution of cytosine for guanine
Description : Proto-oncogenes are: B A. DNA sequences in cells that are oncogenes themselves B. Cellular copies of genes that were first found in oncogenic retroviruses C. DNA viral sequences that are known to infect human cells D. Bacterial DNA counterparts
Last Answer : Cellular copies of genes that were first found in oncogenic retroviruses
Description : Amplification of dihydrofolate reductase gene in a cancer cell makes the cell (A) Susceptible to folic acid deficiency (B) Less malignant (C) Resistant to amethopterin therapy (D) Responsive to amethopterin therapy
Description : Amplification of dihydrofolate reductase gene may be brought about by (A) High concentrations of folic acid (B) Deficiency of folic acid (C) Low concentration of thymidylate (D) Amethopterin
Description : Antibody diversity arises from (A) Gene amplification (B) Gene re-arrangement (C) Alternative splicing (D) All of these
Description : Given below is the presentation of a kind of chromosomal mutation : What is the kind of mutation represented
Last Answer : Given below is the presentation of a kind of chromosomal mutation : What is the kind of ... B. duplication C. inversion D. reciprocal translocation
Description : The most common mechanism of development of resistance to fluoroquinolones is: A. Chromosomal mutation altering affinity of target site B. Plasmid transfer C. Acquisition of drug destroying enzyme D. Acquisition of alternative metabolic pathway
Last Answer : A. Chromosomal mutation altering affinity of target site
Description : Insertion of a base in a gene can cause (A) Change in reading frame (B) Garbled amino acid sequence in the encoded protein (C) Premature termination of translation (D) All of these
Description : Which of the following is transcribed during repression? (A) Structural gene (B) Promoter gene (C) Regulator gene (D) Operator gene
Description : The region of the Lac operon which must be free from structural gene transcription to occur is (A) The operator locus (B) The promoter site (C) The ‘a’ gene (D) The ‘i’ gene
Description : Mutations in promoter regions of genes can cause (A) Premature termination of translation (B) Change in reading frame of downstream structural gene (C) Decreased efficiency of transcription (D) All of these
Description : The coding sequences in lac operon include (A) i gene (B) i gene, operator locus and promoter (C) z, y and a genes (D) i, z, y and a genes
Description : Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) ... holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus
Description : Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these
Description : Transcription of structural genes of lac operon is prevented by binding of the repressor tetramer to (A) i gene (B) Operator locus (C) Promoter (D) z gene
Description : RNA polymerase holoenzyme binds to lac operon at the following site: (A) i gene (B) z gene (C) Operator locus (D) Promoter region
Description : Lac operon is a cluster of (A) Three structural genes (B) Three structural genes and their promoter (C) A regulatory gene, an operator and a promoter (D) A regulatory gene, an operator, a promoter and three structural genes
Description : To commence structural gene transcription the region which should be free on lac operation is (A) Promoter site (B) Operator locus (C) Y gene (D) A gene
Description : The gene which is transcribed during repression is (A) Structural (B) Regulator (C) Promoter (D) Operator
Description : What does an insertion mutation affect?
Last Answer : Feel Free to Answer
Description : How many nucleotides would cause a frame shift mutation for insertion or deletion A. 6 B. 2 C. 3 D. 9?
Last Answer : Need answer
Description : Which of the statements give below is correct with respect to frameshift mutation a) a single nucleotide base change, insertion, or deletion of the genetic material b) Glutamine is replaced by valine c) ... or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.
Last Answer : d) insertions or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.
Description : Which of the following most appropriately describes haemophilia? (a) Chromosomal disorder (b) Dominant gene disorder (c) Recessive gene disorder (d) X-linked recessive gene disorder
Last Answer : (d) X-linked recessive gene disorder
Description : n bacteria, plasmid is (a) extra chromosomal material (b) main DNA (c) non functional DNA (d) repetitive gene.
Last Answer : (a) extra chromosomal material
Description : In bacteria, plasmid is (a) extra chromosomal material (b) main DNA (c) non functional DNA (d) repetitive gene.
Description : Genomic islands are a. Gene Sequences Not Part Of The Chromosomal Genes. b. Adjacent Gene Sequences Unique To One Or A Few Strains In A Species. c. Acquired By HGT. d. Both B And C Are Correct.
Last Answer : d. Both B And C Are Correct.
Description : Transgenic animals may be prepared by introducing a foreign gene into (A) Somatic cells of young animals (B) Testes and ovaries of animals (C) A viral vector and infecting the animals with the viral vector (D) Fertilised egg and implanting the egg into a foster mother
Description : Explain the term Gene amplification. -Biology
Last Answer : An increase in the number of copies of a gene. There may also be an increase in the RNA and protein made from that gene. Gene amplification is common in cancer cells, and some amplified genes may cause cancer cells to grow or become resistant to anticancer drugs.
Description : What is gene amplification? -Biology
Last Answer : answer:
Description : All the following statements about retino blastoma are true except (A) At least two mutations are required for its development (B) One mutation can be inherited from a parent (C) Children ... mutation develop retinoblastoma at a younger age (D) RB 1 gene promotes the development of retinoblastoma
Description : Marfan’s syndrome results from a mutation in the gene coding: (A) Collagen (B) Elastin (C) Fibrillin (D) Keratin
Description : The movement of a gene from one linkage group to another is called (a) translocation (b) crossing over (c) inversion (d) duplication
Last Answer : (c) inversion
Description : The mechanism that causes a gene to move from one linkage group to another is called (a) inversion (b) duplication (c) translocation (d) crossing-over.
Last Answer : (c) translocation
Description : A point mutation occurs in a sex cell of an adult chimpanzee. The mutation is located on a gene responsible for the development of the eye. Which describes the most likely effect of this mutation?
Last Answer : The chimpanzee's offspring will have abnormal eyes.
Description : How is it possible for a point mutation to have no effect on the function of the gene TAC CG?
Description : Technical virology questions about ERVs and RNA vs. DNA viral rates of mutation?
Last Answer : You’re going to make me dig out my old biochemistry texts for this one. Don’t have time now but I’ll do it when I get home from work.