Description : The mechanism of synthesis of DNA and RNA are similar to all the following ways except (A) They involve release of pyrophosphate from each nucleotide added (B) They require activated nucleotide precursor and Mg2+ (C) The direction of synthesis is (D) They require a primer
Last Answer : Answer : D
Description : The mechanism of synthesis of DNA and RNA are similar in all the following ways except (A) They involve release of pyrophosphate from each nucleotide added (B) They require activated nucleotide precursor and Mg2+ (C) The direction of synthesis is 5’ → 3’ (D) They require a primer
Last Answer : Answer : A
Description : Which one of the following statements correctly describes eukaryotic DNA? (A) If uses DNA polymerase with nuclease activities (B) It is replicated bidirectionally at many points (C) It contains no repetitive DNA (D) It is nonlinear
Last Answer : Answer : C
Description : The major determinant of the overall rate of denovo purine nucleotide biosynthesis is the concentration of (A) 5-phosphoribosyl 1-pyrophosphate (B) 5-phospho β-D-ribosylamine (C) Glycinamide ribosyl-5-phosphate (D) Formylglycinamide ribosyl-5-phosphate
Description : RNA synthesis requires (A) RNA primer (B) RNA template (C) DNA template (D) DNA primer
Description : 5-Phosphoribosyl-1-pyrophosphate is required for the synthesis of (A) Purine nucleotides (B) Pyrimidine nucleotides (C) Both (A) and (B) (D) None of these
Description : The key substance in the synthesis of purine, phosphoribosyl pyrophosphate is formed by (A) α-D-ribose 5-phosphate (B) 5-phospho β-D-ribosylamine (C) D-ribose (D) Deoxyribose
Description : Proopiomelanocortin is the precussor of (A) ACTH (B) β-tropin (C) Endorphins (D) All of these
Description : An enzyme promotes a chemical reaction by (A) Lowering the energy of activation (B) Causing the release of heat which acts as a primer (C) Increasing molecular motion (D) Changing the free energy difference between substrate and product
Description : Which one of the following structural formulae of two organic compounds is correctly identified along with its related function? (a) B : Adenine - A nucleotide that makes up nucleic acids (b) A : Triglyceride - ... ) B : Uracil - A component of DNA (d) A : Lecithin - A component of cell membrane
Last Answer : (d) A : Lecithin - A component of cell membrane
Description : Most bacteria do not require the ion a. Mg2+ b. Ca2+ c. Na+ d. Fe+2
Last Answer : Ans: C
Description : After formation of replication fork (A) Both the new strands are synthesized discontinuously (B) One strand is synthesized continuously and the other discontinuously (C) Both the new strands are synthesized continuously (D) RNA primer is required only for the synthesis of one new strand
Last Answer : Answer : B
Description : Glycogenin is (A) Uncoupler of oxidative phosphorylation (B) Polymer of glycogen molecules (C) Protein primer for glycogen synthesis (D) Intermediate in glycogen breakdown
Last Answer : C
Description : Following statements describe the characteristics of the enzyme restriction endonuclease. Identify the incorrect statement. (a) The enzyme recognises a specific palindromic nucleotide sequence in the DNA. (b) ... (d) The enzyme cuts the sugar-phosphate backbone at specific sites on each strand.
Last Answer : (c) The enzyme binds DNA at specific sites and cuts only one of the two strands.
Description : How would the transcription of the eukaryotic gene be affected if a replication error changed the nucleotide sequence of the termination signal for that gene?
Last Answer : Extra long proteins are likely to fold improperly and notfunction correctly. The overall health of the individual would bedestroyed.
Description : The normal function of restriction endonucleases is to (A) Excise introns from hrRNA (B) Polymerize nucleotides to form RNA (C) Remove primer from okazaki fragments (D) Protect bacteria from foreign DNA
Description : Ribonucleotides of RNA primer are replaced by deoxyribonucleotides by the enzyme: (A) DNA polymerase I (B) DNA polymerase II (C) DNA polymerase III holoenzyme (D) All of these
Description : Deoxyribonucleotides are added to RNA primer by (A) DNA polymerase I (B) DNA polymerase II (C) DNA polymerase III holoenzyme (D) All of these
Description : RNA primer is formed by the enzyme: (A) Ribonuclease (B) Primase (C) DNA polymerase I (D) DNA polymerase III
Description : If no primer DNA was given, the following scientist could not have synthesized DNA. (A) Ochoa (B) Okazaki (C) Kornberg (D) Monod
Description : The first pyrimidine nucleotide to be formed in de novo synthesis pathway is (A) UMP (B) CMP (C) CTP (D) TMP
Description : The first reaction unique to purine nucleotide synthesis is catalysed by (A) PRPP synthetase (B) PRPP glutamyl amido transferase (C) Phosphoribosyl glycinamide synthetase (D) Formyl transferase
Description : All of the following enzymes are unique to purine nucleotide synthesis except (A) PRPP synthetase (B) PRPP glutamyl amido transferase (C) Adenylosuccinate synthetase (D) IMP dehydrogenase
Description : De novo synthesis of purine nucleotide occurs in (A) Mitochondria (B) Cytosol (C) Microsmes (D) Ribosomes
Description : DNA finger printing is based on the presence in DNA of (A) Constant number of tandem repeats (B) Varibale number of tandem repeats (C) Non-repititive sequences in each DNA (D) Introns in eukaryotic DNA
Description : The eukaryotic nuclear chromosomal DNA (A) Is a linear and unbranched molecule (B) Is not associated with a specific membranous organelle (C) Is not replicated semiconservatively (D) Is about of the same size as each prokaryotic chromoses
Description : Which of the statements give below is correct with respect to frameshift mutation a) a single nucleotide base change, insertion, or deletion of the genetic material b) Glutamine is replaced by valine c) ... or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.
Last Answer : d) insertions or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.
Description : Direction of DNA synthesis is (A) 5’ → 3’ (B) 3’ → 5’ (C) Both (A) and (B) (D) None of these
Description : The genetic code operates via (A) The protein moiety of DNA (B) The base sequences of DNA (C) The nucleotide sequence of mRNA (D) The base sequence of tRNA
Description : The genetic code operates through (A) The protein moiety of DNA (B) Cistrom of DNA (C) Nucleotide sequence of m RNA (D) The anticodons of tRNA
Description : What is the principal cation of intracellular fluid? (A) K+ (B) Na+ (C) Ca2+ (D) Mg2+
Description : Action of glycogen synthase is inhibited by (A) Insulin (B) Glucose (C) Mg2+ (D) Cyclic AMP
Description : Pyruvate kinase requires ______ ions for maximum activity. (A) Na+ (B) K+ (C) Ca2+ (D) Mg2+
Last Answer : B
Description : A common substrate of HGPRTase, APRTase and PRPP glutamyl amidotransferase is (A) Ribose 5 phosphate (B) Phosphoribosyl pyrophosphate (C) Hypoxanthine (D) Adenosine
Description : When ATP forms AMP (A) Inorganic pyrophosphate is produced (B) Inorganic phosphorous is produced (C) Phsophagen is produced (D) No energy is produced
Description : Of Which warburg’s yellow enzyme contains as a prosthetic group? (A) Thiamine pyrophosphate (B) Biotin (C) NAD+ (D) Riboflavin-5-phosphate
Description : Decarboxylation of α-keto acids requires (A) Thiamine pyrophosphate, FAD, NAD+ (B) Flavin mononucleotide (C) NADP+ (D) NAD+ only
Description : Which one of the following transfers acyl groups? (A) Thiamine pyrophosphate (B) Lipomide (C) ATP (D) NADH
Description : A coenzyme present in phosphorylase is (A) NAD (B) Pyridoxal phosphate (C) Thiamin pyrophosphate (D) Coenzyme A
Description : In the biosynthesis of cholesterol, the step which controls the rate and locus of metabolic regulation is (A) Geranyl pyrophosphate farnesyl pyrophosphate (B) Squalene → lanosterol (C) HMG CoA → mevalonate (D) Lanosterol → 1, 4-desmethyl lanosterol
Description : Cocarboxylase is (A) Thiamine pyrophosphate (B) Pyridoxal phosphate (C) Biotin (D) CoA
Description : Fully activated pyruvate carboxylase depends upon the presence of (A) Malate and Niacin (B) Acetyl CoA and biotin (C) Acetyl CoA and thiamine pyrophosphate (D) Oxaloacetate and biotin
Description : The oxidation of lactic acid to pyruvic acid requires the following vitamin derivative as the hydrogen carrier. (A) Lithium pyrophosphate (B) Coenyzme A (C) NAD+ (D) FMN
Description : For production of eukaryotic protein by recombinant DNA technology in bacteria, the template used is (A) Eukaryotic gene (B) hnRNA (C) mRNA (D) All of these
Description : Reverse transcriptase activity is present in the eukaryotic: (A) DNA polymerase α (B) DNA polymerase γ (C) Telomerase (D) DNA polymerase II
Description : In DNA sequencing, the primer A.specifies where the sequence ends B.specifies where the sequence begins C.both (a) and (b) D.generates variety of different sized fragments
Last Answer : B.specifies where the sequence begins
Description : What is the role of NAD+ in cellular respiration? (a) It functions as an enzyme. (b) It functions as an electron carrier. (c) It is a nucleotide source for ATP synthesis. (d) It is the final electron acceptor for anaerobic respiration.
Last Answer : c) It is a nucleotide source for ATP synthesis.
Description : What is the role of NAD+ in cellular respiration ? (1) It functions as an enzymes (2) It functions as an electron carrier (3) It is a nucleotide source for ATP synthesis (4) It is the final electron acceptor for anaerobic respiration
Last Answer : (2) It functions as an electron carrier
Description : All of the following statements about eukaryotic promoters are true except (A) They may be located upstream or down stream from the structural gene (B) They have two consensus sequences ( ... (D) Mutations in promoter region can decrease the efficiency of transcription of the structural gene
Description : All of the following statements about bacterial promoters are true except (A) They are smaller than eukaryotic promoters (B) They have two consensus sequences upstream from the transcription star site (C) ... is the site for attachment of RNA polymerase (D) TATA box has a high melting temperature