Proopiomelanocortin is the precussor of (A) ACTH (B) β-tropin (C) Endorphins (D) All of these

Proopiomelanocortin is the precussor of (A) ACTH (B) β-tropin (C) Endorphins (D) All of these
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All the following statements about proopiomelanocortin are true except (A) It is made up of 285 amino acids (B) It is synthesised in pars intermedia and anterior lobe of pituitary gland (C) It is the precursor of ACTH and melatonin (D) It is the precursor of corticotropin like intermediate lobe peptide and endorphins 218 MCQs IN BIOCHEMISTRY

Description : All the following statements about proopiomelanocortin are true except (A) It is made up of 285 amino acids (B) It is synthesised in pars intermedia and anterior lobe of pituitary gland ... ) It is the precursor of corticotropin like intermediate lobe peptide and endorphins 218 MCQs IN BIOCHEMISTRY

Last Answer : Answer : C

The immediate parent of α, β and γ endorphins is (A) Pro-opiomelanocortin (B) β-lipotropin (C) ATCH (D) Lipoprotein

Description : The immediate parent of α, β and γ endorphins is (A) Pro-opiomelanocortin (B) β-lipotropin (C) ATCH (D) Lipoprotein

Last Answer : Answer : B

Corticotropin releasing hormone controls the direct release of (A) Pro-opiomelanocortin (B) α MSH (C) β MSH (D) Endorphins

Description : Corticotropin releasing hormone controls the direct release of (A) Pro-opiomelanocortin (B) α MSH (C) β MSH (D) Endorphins

Last Answer : Answer : A

All of the following can be formed from pro-opiomelanocortin except (A) α-and β-MSH (B) β-and γ-Lipotropins (C) α-and β-Endorphins(D) FSH

Description : All of the following can be formed from pro-opiomelanocortin except (A) α-and β-MSH (B) β-and γ-Lipotropins (C) α-and β-Endorphins(D) FSH

Last Answer : Answer : D

Which one of the following statements correctly describes eukaryotic DNA? (A) They involve release of pyrophosphate from each nucleotide precussor and Mg2+ (B) The direction of synthesis is (C) They require a primer 5’→ 3’ (D) None of these

Description : Which one of the following statements correctly describes eukaryotic DNA? (A) They involve release of pyrophosphate from each nucleotide precussor and Mg2+ (B) The direction of synthesis is (C) They require a primer 5’→ 3’ (D) None of these

Last Answer : Answer : C

Following are presumed to act as transmitters in the natural control of pain a. Enkephalins b. endorphins c. both d. none of them

Description : Following are presumed to act as transmitters in the natural control of pain a. Enkephalins b. endorphins c. both d. none of them

Last Answer : both

Following morphine like substance are found in the thalamus of the brain a. Enkephalins b. endorphins c. both d. none of them

Description : Following morphine like substance are found in the thalamus of the brain a. Enkephalins b. endorphins c. both d. none of them

Last Answer : both

Prostaglandins are chemical substances thought to a) increase sensitivity of pain receptors. Prostaglandins are believed to increase sensitivity to pain receptors by enhancing the pain-provoking effect of bradykinin. b) reduce the perception of pain. Endorphins and enkephalins reduce or inhibit transmission or perception of pain. c) inhibit the transmission of pain. Endorphins and enkephalins reduce or inhibit transmission or perception of pain. d) inhibit the transmission of noxious stimuli. Morphine and other opioid medications inhibit the transmission of noxious stimuli by mimicking enkephalin and endorphin.

Description : Prostaglandins are chemical substances thought to a) increase sensitivity of pain receptors. Prostaglandins are believed to increase sensitivity to pain receptors by enhancing the pain-provoking ... opioid medications inhibit the transmission of noxious stimuli by mimicking enkephalin and endorphin.

Last Answer : a) increase sensitivity of pain receptors. Prostaglandins are believed to increase sensitivity to pain receptors by enhancing the pain-provoking effect of bradykinin.

Opioid analgesics reduce pain by the release of which naturally appearing product:CHECK A. Serotonin B. Histamine C. Enkephalins/endomorphins/endorphins/dynorphines

Description : Opioid analgesics reduce pain by the release of which naturally appearing product:CHECK A. Serotonin B. Histamine C. Enkephalins/endomorphins/endorphins/dynorphines

Last Answer : C. Enkephalins/endomorphins/endorphins/dynorphines

Body water is regulated by the hormone: (A) Oxytocin (B) ACTH (C) FSH (D) Epinephrine

Description : Body water is regulated by the hormone: (A) Oxytocin (B) ACTH (C) FSH (D) Epinephrine

Last Answer : Answer : A

Which of the following hormones is not involved in carbohydrate metabolism? (A) ACTH (B) Glucagon (C) Vasopressin (D) Growth hormone

Description : Which of the following hormones is not involved in carbohydrate metabolism? (A) ACTH (B) Glucagon (C) Vasopressin (D) Growth hormone

Last Answer : Answer : C

Gastric Secretion is regulated by the hormone: (A) Glucagon (B) Gastrin (C) Epinephrin (D) ACTH

Description : Gastric Secretion is regulated by the hormone: (A) Glucagon (B) Gastrin (C) Epinephrin (D) ACTH

Last Answer : Answer : B

Which of the following hormone is not under the control of ACTH? (A) Aldosterone (B) Cortisol (C) Corticosterone (D) Deoxycorticosterone

Description : Which of the following hormone is not under the control of ACTH? (A) Aldosterone (B) Cortisol (C) Corticosterone (D) Deoxycorticosterone

Last Answer : Answer : A

Which one of the following is not liberated by the adenohypophysis? (A) Growth hormone (B) TSH (C) ACTH (D) Gonadotropin

Description : Which one of the following is not liberated by the adenohypophysis? (A) Growth hormone (B) TSH (C) ACTH (D) Gonadotropin

Last Answer : Answer : D

Secretion of androgens is increased by (A) LH (B) FSH (C) ACTH (D) Growth hormone

Description : Secretion of androgens is increased by (A) LH (B) FSH (C) ACTH (D) Growth hormone

Last Answer : Answer : A

Secretion of mineralcorticoids is increased by (A) ACTH (B) Angiotensin (C) Hypokalaemia (D) Hypernatraemia

Description : Secretion of mineralcorticoids is increased by (A) ACTH (B) Angiotensin (C) Hypokalaemia (D) Hypernatraemia

Last Answer : Answer : B

Acromegaly results from overproduction of (A) ACTH during childhood (B) TSH during adult life (C) Growth hormone during childhood (D) Growth hormone during adult life HORMONE METABOLISM 219

Description : Acromegaly results from overproduction of (A) ACTH during childhood (B) TSH during adult life (C) Growth hormone during childhood (D) Growth hormone during adult life HORMONE METABOLISM 219

Last Answer : Answer : D

Hormonal activity of ACTH is completely lost on removal of (A) 5 C-terminal amino acids (B) 10 C-terminal amino acids (C) 15 C-terminal amino acids (D) None of these

Description : Hormonal activity of ACTH is completely lost on removal of (A) 5 C-terminal amino acids (B) 10 C-terminal amino acids (C) 15 C-terminal amino acids (D) None of these

Last Answer : Answer : D

ACTH is a polypeptide made up of (A) 39 amino acids (B) 41 amino acids (C) 51 amino acids (D) 84 amino acids

Description : ACTH is a polypeptide made up of (A) 39 amino acids (B) 41 amino acids (C) 51 amino acids (D) 84 amino acids

Last Answer : Answer : A

Regulation of ACTH secretion occurs through (A) Corticotropin releasing hormone (CRH) and corticotropin release inhibiting hormone (CRIH) of hypothalamus (B) Feedback inhibition by cortisol (C) CRH and feedback inhibition by cortisol (D) CRIH and feedback inhibition by cortisol

Description : Regulation of ACTH secretion occurs through (A) Corticotropin releasing hormone (CRH) and corticotropin release inhibiting hormone (CRIH) of hypothalamus (B) Feedback inhibition by cortisol (C) CRH and feedback inhibition by cortisol (D) CRIH and feedback inhibition by cortisol

Last Answer : Answer : C

All the following statements about ACTH are true except (A) It is a tropic hormone (B) Its target cells are located in adrenal cortex (C) Its receptors are located in the cell membrane (D) Its second messenger is inositol triphosphate

Description : All the following statements about ACTH are true except (A) It is a tropic hormone (B) Its target cells are located in adrenal cortex (C) Its receptors are located in the cell membrane (D) Its second messenger is inositol triphosphate

Last Answer : Answer : D

Precursor of ACTH is (A) Cholesterol (B) Pregnenolone (C) Corticotropin (D) Pro-opiomelanocortin

Description : Precursor of ACTH is (A) Cholesterol (B) Pregnenolone (C) Corticotropin (D) Pro-opiomelanocortin

Last Answer : Answer : D

A nonapeptide among the following is (A) Antidiuretic hormone (B) Insulin (C) ACTH (D) Thyrotropin releasing hormone

Description : A nonapeptide among the following is (A) Antidiuretic hormone (B) Insulin (C) ACTH (D) Thyrotropin releasing hormone

Last Answer : Answer : A

Secretion of MSH is regulated by (A) Feedback mechanism (B) Melatonin (C) Hypothalamic hormones (D) ACTH HORMONE METABOLISM 217

Description : Secretion of MSH is regulated by (A) Feedback mechanism (B) Melatonin (C) Hypothalamic hormones (D) ACTH HORMONE METABOLISM 217

Last Answer : Answer : C

Cyclic AMP acts as the second messenger for all of the following except (A) Oxytocin (B) TSH (C) ACTH (D) FSH 216 MCQs IN BIOCHEMISTRY

Description : Cyclic AMP acts as the second messenger for all of the following except (A) Oxytocin (B) TSH (C) ACTH (D) FSH 216 MCQs IN BIOCHEMISTRY

Last Answer : Answer : A

The production of progesterone by corpus luteum cell is stimulated by (A) LH (B) TSH (C) ACTH (D) MSH

Description : The production of progesterone by corpus luteum cell is stimulated by (A) LH (B) TSH (C) ACTH (D) MSH

Last Answer : Answer : A

A hormone which cannot cross the blood brain barrier is (A) Epinephrine (B) Aldosterone (C) ACTH (D) TSH

Description : A hormone which cannot cross the blood brain barrier is (A) Epinephrine (B) Aldosterone (C) ACTH (D) TSH

Last Answer : Answer : A

The circulating concentration of ACTH in plasma is (A) 0.05 mµ/100 ml (B) 0.1–2.0 mµ/100 ml (C) 2.5–3.5 mµ/100 ml (D) 3.0–5.0 mµ/100 ml

Description : The circulating concentration of ACTH in plasma is (A) 0.05 mµ/100 ml (B) 0.1–2.0 mµ/100 ml (C) 2.5–3.5 mµ/100 ml (D) 3.0–5.0 mµ/100 ml

Last Answer : Answer : B

ACTH induces rise in (A) Cyclic AMP (B) Cyclic GMP (C) Calcium (D) Magnesium

Description : ACTH induces rise in (A) Cyclic AMP (B) Cyclic GMP (C) Calcium (D) Magnesium

Last Answer : Answer : A

Excessive secretion of ACTH causes (A) Cushing’s syndrome (B) Addison’s disease (C) Myxoedema (D) Thyrotoxicosis

Description : Excessive secretion of ACTH causes (A) Cushing’s syndrome (B) Addison’s disease (C) Myxoedema (D) Thyrotoxicosis

Last Answer : Answer : A

ACTH stimulates the secretion of (A) Glucocorticoids (B) Epinephrine (C) Thyroxine (D) Luteinizing hormone

Description : ACTH stimulates the secretion of (A) Glucocorticoids (B) Epinephrine (C) Thyroxine (D) Luteinizing hormone

Last Answer : Answer : A

Biological activity of ACTH requires (A) 10-N-terminal amino acid (B) 24-N-terminal amino acid (C) 24-C-terminal amino acid (D) 15-C-terminal amino acid

Description : Biological activity of ACTH requires (A) 10-N-terminal amino acid (B) 24-N-terminal amino acid (C) 24-C-terminal amino acid (D) 15-C-terminal amino acid

Last Answer : Answer : B

Adrenocorticotropic hormone (ACTH) is a single polypeptide containing (A) 25 amino acid (B) 39 amino acid (C) 49 amino acid (D) 52 amino acid 208 MCQs IN BIOCHEMISTRY

Description : Adrenocorticotropic hormone (ACTH) is a single polypeptide containing (A) 25 amino acid (B) 39 amino acid (C) 49 amino acid (D) 52 amino acid 208 MCQs IN BIOCHEMISTRY

Last Answer : Answer : B

The hormone activating the glycogen synthase activity is (A) Insulin (B) Glucagon (C) Epinephrine (D) ACTH

Description : The hormone activating the glycogen synthase activity is (A) Insulin (B) Glucagon (C) Epinephrine (D) ACTH

Last Answer : Answer : A

Protein anabolism is stimulated by (A) ACTH (B) Testosterone (C) Glucagon (D) Epinephrine

Description : Protein anabolism is stimulated by (A) ACTH (B) Testosterone (C) Glucagon (D) Epinephrine

Last Answer : Answer : B

Protein anabolism is stimulated by (A) ACTH (B) Testosterone (C) Glucagon (D) Epinephrine

Description : Protein anabolism is stimulated by (A) ACTH (B) Testosterone (C) Glucagon (D) Epinephrine

Last Answer : Answer : B

Which of the following hormones is not involved in carbohydrate metabolism? (A) Cortisol (B) ACTH (C) Glucogen (D) Vasopressin

Description : Which of the following hormones is not involved in carbohydrate metabolism? (A) Cortisol (B) ACTH (C) Glucogen (D) Vasopressin

Last Answer : D

Reactivation of inactive liver phosphorylase is normally favoured by (A) Insulin (B) Epinephrine (C) ACTH (D) Glucagon

Description : Reactivation of inactive liver phosphorylase is normally favoured by (A) Insulin (B) Epinephrine (C) ACTH (D) Glucagon

Last Answer : D

Which of the following techniques would be most useful in the differential diagnosis between ectopic Cushing's syndrome and pituitary dependent Cushing's disease. 1) Urine free cortisol 2) High dose Dexamethasone suppression test 3) ACTH concentrations 4) Inferior petrosal sinus sampling 5) CRF test

Description : Which of the following techniques would be most useful in the differential diagnosis between ectopic Cushing's syndrome and pituitary dependent Cushing's disease. 1) Urine free cortisol 2) ... Dexamethasone suppression test 3) ACTH concentrations 4) Inferior petrosal sinus sampling 5) CRF test

Last Answer : Answers-4 Inferior petrosal sinus sampling with an elevated central ACTH concentration compared with the peripheral value is the most valuable test in the differential diagnosis of either Cushing's disease or ectopic Cushing's syndrome. The other tests are far less useful in comparison.

ACTH is secreted by

Description : ACTH is secreted by

Last Answer : ACTH is secreted by A. Thyroid gland B. Thymus gland C. Pituitary gland D. Islets of Langerhans

ACTH (cosyntropin) stimulation test?

Description : ACTH (cosyntropin) stimulation test?

Last Answer : DefinitionACTH (cosyntropin) stimulation test measures how well the adrenal glands respond to the hormone ACTH. ACTH is a hormone produced in the pituitary gland that stimulates the adrenal glands to release ... .Next, the health care provider gently inserts a needle into the vein. The blood collec

Which of the following statement(s) is/are true concerning hypoadrenal shock? a. In the United States, idiopathic adrenal atrophy (Addison’s disease) is the most common cause b. Laboratory abnormalities include hyponatremia, hypochloremia, and hyperkalemia c. Fever may be seen with hypoadrenal shock d. ACTH stimulation test is the diagnostic test of choice to confirm hypoadrenal shock

Description : Which of the following statement(s) is/are true concerning hypoadrenal shock? a. In the United States, idiopathic adrenal atrophy (Addison's disease) is the most common cause b. Laboratory ... hypoadrenal shock d. ACTH stimulation test is the diagnostic test of choice to confirm hypoadrenal shock

Last Answer : Answer: b, c, d Shock of a dramatic nature, poorly responsive to resuscitation, may develop as a consequence of adrenal insufficiency. In this country, adrenal insufficiency most ... of an ACTH stimulation test. A significant major cortisol response should be elicited by ACTH administration

A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic hormone (ACTH) is secreted from the anterior pituitary gland b. ACTH stimulation results in elevation of serum cortisol levels for up to a week after the operation c. An increased secretion of aldosterone and ADH may contribute to postoperative fluid retention d. An increase in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis

Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis

Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained

True statements concerning hypoadrenal shock include which of the following? A. Adrenocortical insufficiency may manifest itself as severe shock refractory to volume and pressor therapy. B. The presence of hyperglycemia and hypotension may suggest the diagnosis of shock due to adrenocortical insufficiency. C. Hydrocortisone does not interfere with the serum cortisol assay and should be given to hemodynamically unstable patients suspected of having hypoadrenal shock. D. The rapid adrenocorticotropic hormone (ACTH) stimulation test should be performed to help establish the diagnosis of acute adrenocortical insufficiency.

Description : True statements concerning hypoadrenal shock include which of the following? A. Adrenocortical insufficiency may manifest itself as severe shock refractory to volume and pressor therapy. B. ... test should be performed to help establish the diagnosis of acute adrenocortical insufficiency.

Last Answer : Answer: AD DISCUSSION: Shock due to acute adrenocortical insufficiency is relatively uncommon but must be considered when shock refractory to volume replacement and pressor therapy is present. ... and it is the corticosteroid of choice while the ACTH stimulation test is being performed

The following are true about the hormones secreted by the adrenal cortex: a. zona fasciculata secretes cortisol b. zona glomerulosa secretes aldosterone c. secretion of aldosterone is stimulated by ACTH d. all

Description : The following are true about the hormones secreted by the adrenal cortex: a. zona fasciculata secretes cortisol b. zona glomerulosa secretes aldosterone c. secretion of aldosterone is stimulated by ACTH d. all

Last Answer : all

True statements about aldosterone include: a. secretion is mainly under the control of adrenocorticotrophic (ACTH) hormone secretion b. increases hepatic gluconeogenesis c. its secretion is stimulated by angiotensin d. in the kidney, mainly acts on the proximal convoluted tubules

Description : True statements about aldosterone include: a. secretion is mainly under the control of adrenocorticotrophic (ACTH) hormone secretion b. increases hepatic gluconeogenesis c. its secretion is stimulated by angiotensin d. in the kidney, mainly acts on the proximal convoluted tubules

Last Answer : its secretion is stimulated by angiotensin

The following are true about the antidiuretic hormone: a. it is produced by the anterior pituitary gland b. it reduces the cardiac output c. it increases the renal absorption of sodium d. it decreases the release of ACTH

Description : The following are true about the antidiuretic hormone: a. it is produced by the anterior pituitary gland b. it reduces the cardiac output c. it increases the renal absorption of sodium d. it decreases the release of ACTH

Last Answer : it increases the renal absorption of sodium

The followings are steroid hormones: a. corticotrophic hormone (ACTH) b. aldosterone c. thyroxine d. growth hormone

Description : The followings are steroid hormones: a. corticotrophic hormone (ACTH) b. aldosterone c. thyroxine d. growth hormone

Last Answer : aldosterone

Which hormone causes dilation of blood vessels, increased oxygen consumption and glucogenesis? (a) Glucagon (b) ACTH (c) Insulin (d) Adrenaline

Description : Which hormone causes dilation of blood vessels, increased oxygen consumption and glucogenesis? (a) Glucagon (b) ACTH (c) Insulin (d) Adrenaline

Last Answer : (d) Adrenaline

A middle aged female presented with following symptoms - Hirsutism, fragility of skin, with easy bruising, broad purplish striae and signs of proximal myopathy. The first step in confirming the diagnosis will be Options: 1) Advice 24 hours urinary free cortisol excretion 2) Exclude exogenous Glucocorticoid use 3) Advice plasma ACTH estimation 4) Advice dexamethasone overnight test

Description : A middle aged female presented with following symptoms - Hirsutism, fragility of skin, with easy bruising, broad purplish striae and signs of proximal myopathy. The first step in ... Exclude exogenous Glucocorticoid use 3) Advice plasma ACTH estimation 4) Advice dexamethasone overnight test

Last Answer : Correct Answer: 2) Exclude exogenous Glucocorticoid use