What are monoclonal antibodies?

What are monoclonal antibodies?
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A type of protein made in the laboratory that can bind to substances in the body, including cancer cells. There are many kinds of monoclonal antibodies. A monoclonal antibody is made so that it binds to only one substance. Monoclonal antibodies are being used to treat some types of cancer. They can be used alone or to carry drugs, toxins, or radioactive substances directly to cancer cells.
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Are you hearing that people who won’t get vaccinated are instead getting monoclonal antibodies?

Description : Are you hearing that people who won’t get vaccinated are instead getting monoclonal antibodies?

Last Answer : And the monoclonal antibodies don’t work that well anyway.

Am I correct that people against fetal stem cell research are ok taking monoclonal antibodies?

Description : Am I correct that people against fetal stem cell research are ok taking monoclonal antibodies?

Last Answer : I smell discreet advertisement… This is a tactics employed in my country when the antivax became a trend here. Vaccines are harmful, so buy our stuff instead!

Assertion: The antibodies separated from serum are homogenous. Reason : Monoclonal antibodies are homogenous immunological reagents.

Description : Assertion: The antibodies separated from serum are homogenous. Reason : Monoclonal antibodies are homogenous immunological reagents.

Last Answer : Assertion: The antibodies separated from serum are homogenous. Reason : Monoclonal antibodies are ... both the assertion and reason are false

What medical conditions require the use of monoclonal antibodies?

Description : What medical conditions require the use of monoclonal antibodies?

Last Answer : Monoclonal antibodies work on specific cells. They are used in cancer treatment and in the treatment of autoimmune diseases.

What diseases are being treated with monoclonal antibodies?

Description : What diseases are being treated with monoclonal antibodies?

Last Answer : Uses for monoclonal antibodies include: Cancer Rheumatoid Arthritis Multiple sclerosis Cardiovascular disease Systemic lupus erythematosus Crohn's disease Ulcerative colitis Psoriasis

Monoclonal antibodies are prepared by cloning (A) Myeloma cells (B) Hybridoma cells (C) T-Lymphocytes (D) B-Lymphocytes

Description : Monoclonal antibodies are prepared by cloning (A) Myeloma cells (B) Hybridoma cells (C) T-Lymphocytes (D) B-Lymphocytes

Last Answer : Answer : B

Antibodies produced by a single clone of myeloma cells are referred to as _____ antibodies. a. Chimeric b. Monoclonal c. Polyclonal d. Hybrid

Description : Antibodies produced by a single clone of myeloma cells are referred to as _____ antibodies. a. Chimeric b. Monoclonal c. Polyclonal d. Hybrid

Last Answer : b. Monoclonal

A hybridoma cell a. Secretes monoclonal antibodies. b. Presents antigens on its surface. c. Secretes polyclonal antibodies. d. Is an antigen-presenting cell

Description : A hybridoma cell a. Secretes monoclonal antibodies. b. Presents antigens on its surface. c. Secretes polyclonal antibodies. d. Is an antigen-presenting cell

Last Answer : d. Is an antigen-presenting cell

The drug, Interleukin-2, is an example of which type of biologic response modifier? a) Cytokine Other cytokines include interferon alfa and filgrastim. b) Monoclonal antibodies Monoclonal antibodies include rituximab, trastuzumab, and gemtuzumab. c) Retinoids Retinoic acid is an example of a retinoid. d) Antimetabolites Antimetabolites are cell cycle-specific antineoplastic agents.

Description : The drug, Interleukin-2, is an example of which type of biologic response modifier? a) Cytokine Other cytokines include interferon alfa and filgrastim. b) Monoclonal antibodies Monoclonal ... an example of a retinoid. d) Antimetabolites Antimetabolites are cell cycle-specific antineoplastic agents.

Last Answer : a) Cytokine Other cytokines include interferon alfa and filgrastim.

Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin's Lymphoma? (A) Infliximab (B) Abciximab (C) Gemtuzumab (D) Rituximab

Description : Which of the following monoclonal antibodies is prescribed for patients with non-Hodgkin's Lymphoma? (A) Infliximab (B) Abciximab (C) Gemtuzumab (D) Rituximab

Last Answer : (D) Rituximab

Uses of monoclonal antibodies

Description : Uses of monoclonal antibodies

Last Answer : 1) Monoclonal antibodies help in immunodiagnosis by detection of a particular antigen or antibody. 2) Many tumor-specific antibodies help in tumor detection. 3) Some of the monoclonal antibodies ... in the purification of cells in order to generate the info about their features and functions.

How Monoclonal Antibody differs from Polyclonal Antibody?

Description : How Monoclonal Antibody differs from Polyclonal Antibody?

Last Answer : If an antigen is injected into an animal, a number of antibody-producing cells will bind that antigen albeit with varying degrees of affinity, and so the antibody which appears in the ... as therapeutic tools, for example to inactivate bacterial toxins and to treat certain forms of cancer.

How Monoclonal Antibody differs from Polyclonal Antibody?

Description : How Monoclonal Antibody differs from Polyclonal Antibody?

Last Answer : If an antigen is injected into an animal, a number of antibody-producing cells will bind that antigen albeit with varying degrees of affinity, and so the antibody which appears in the ... therapeutic tools, for example to inactivate bacterial toxins and to treat certain forms of cancer. 

The following is true of abciximab except: A. It is a monoclonal antibody against GPIIb/IIIa B. It inhibits platelet aggregation induced by a variety of platelet agonists C. It is antigenic D. It is used to reduce the risk of restenosis in patients undergoing PTCA

Description : The following is true of abciximab except: A. It is a monoclonal antibody against GPIIb/IIIa B. It inhibits platelet aggregation induced by a variety of platelet agonists C. It is antigenic D. It is used to reduce the risk of restenosis in patients undergoing PTCA

Last Answer : C. It is antigenic

A monoclonal antibody is specific for how many different proteins?

Description : A monoclonal antibody is specific for how many different proteins?

Last Answer : ANSWER: ONE

Do you know about thyroid antibodies/Hashimoto testing?

Description : Do you know about thyroid antibodies/Hashimoto testing?

Last Answer : Need Answer

If you contract West Nile virus do you develope antibodies for future exposure?

Description : If you contract West Nile virus do you develope antibodies for future exposure?

Last Answer : Yes. This was extremely helpful to Marty McFly when he met Biff in the future as Biff was a carrier of the Wet Nile Virus. That’s how the movies went, right?

Has anyone treated or been treated for thyroid antibodies?

Description : Has anyone treated or been treated for thyroid antibodies?

Last Answer : answer:If you would, please post info or links for alt treatments. I’m a Hashimoto’s case myself and would be interested in alt treatment info. (I’ve only done Synthroid and denial.) Also, Mary Shomon is a patient advocate type with a book or two about thyroid issues that you may find worthwhile.

What is the function of IgM Antibodies? -Biology

Description : What is the function of IgM Antibodies? -Biology

Last Answer : answer:

What is the function of IgG Antibodies? -Biology

Description : What is the function of IgG Antibodies? -Biology

Last Answer : answer:

What is the function of IgA Antibodies? -Biology

Description : What is the function of IgA Antibodies? -Biology

Last Answer : answer:

What is the function of IgD Antibodies? -Biology

Description : What is the function of IgD Antibodies? -Biology

Last Answer : answer:

What is the function of IgE Antibodies? -Biology

Description : What is the function of IgE Antibodies? -Biology

Last Answer : answer:

what is the difference between blood group A and group B (types of antibodies and antigens) ? -Biology

Description : what is the difference between blood group A and group B (types of antibodies and antigens) ? -Biology

Last Answer : answer:

What are antibodies ?

Last Answer : There are two main constituents in the blood, one of which is antibody

Assertion : Artificially acquired passive immunity results when antibodies or lymphocytes produced outside the host are introduced into a host. Reason

Description : Assertion : Artificially acquired passive immunity results when antibodies or lymphocytes produced outside the host are introduced into a host. Reason

Last Answer : Assertion : Artificially acquired passive immunity results when antibodies or lymphocytes produced outside ... both the assertion and reason are false

Assertion : Interferons are a type of antibodies produced by body cells infected by bacteria. Reason : Interferons stimulate inflammation at the site

Description : Assertion : Interferons are a type of antibodies produced by body cells infected by bacteria. Reason : Interferons stimulate inflammation at the site

Last Answer : Assertion : Interferons are a type of antibodies produced by body cells infected by bacteria. Reason ... . If both the assertion and reason are false

Lysis of foreign cell is initiated by antibodies of:

Description : Lysis of foreign cell is initiated by antibodies of:

Last Answer : Lysis of foreign cell is initiated by antibodies of: A. IgM B. IgA C. IgE D. IgM and IgG

If you suspect major deficiency of antibodies in a person, to which of the following would you look for confirmatory evidence

Description : If you suspect major deficiency of antibodies in a person, to which of the following would you look for confirmatory evidence

Last Answer : If you suspect major deficiency of antibodies in a person, to which of the following would ... Haemocytes C. Serum globulins D. Fibrinogen in plasma

In which blood group,antibodies are absent ?

Description : In which blood group,antibodies are absent ?

Last Answer : In which blood group,antibodies are absent ? A. A B. B C. AB D. O

The Rh antibodies from the mother (Rh-ve) can leak into the blood of the foetus (Rh `+ve)` and destroy the `:-`

Description : The Rh antibodies from the mother (Rh-ve) can leak into the blood of the foetus (Rh `+ve)` and destroy the `:-`

Last Answer : The Rh antibodies from the mother (Rh-ve) can leak into the blood of the foetus (Rh `+ve)` and destroy ... RBCs C. Foetal WBCs D. both (1) and (2)

The most abundant antibodies are

Description : The most abundant antibodies are

Last Answer : The most abundant antibodies are A. IgG B. IgA C. IgE D. IgM

What cells produce antibodies to help fight infection?

Description : What cells produce antibodies to help fight infection?

Last Answer : Need answer

What of these allows the body to develop antibodies that keep it from catching the same disease again?

Description : What of these allows the body to develop antibodies that keep it from catching the same disease again?

Last Answer : Need answer

Platelet associated antibodies?

Description : Platelet associated antibodies?

Last Answer : DefinitionA test for platelet-associated antibodies shows whether you have antibodies that are directed against platelets in your blood.How the test is performedBlood is typically drawn from a vein, usually from ... site is covered to stop any bleeding.In infants or young children, a sharp tool call

Antiparietal cells antibodies test?

Description : Antiparietal cells antibodies test?

Last Answer : DefinitionThe antiparietal cells antibodies test measures the presence of antibodies against the parietal cells of the stomach. The parietal cells make and release intrinsic factor and stomach acid. Intrinsic factor ... an airtight vial or tube attached to the needle. The elastic band is removed fr

What kind of antibodies are found in 0 negative blood?

Description : What kind of antibodies are found in 0 negative blood?

Last Answer : Type O negative blood has antibodies against both A and B type blood. This means that you can give blood to any type of blood (A, B, O) but can only receive your exact blood type. Type O negative is one of the most rare types, and is known as the "universal donor".

How do plasma cells produce antibodies?

Description : How do plasma cells produce antibodies?

Last Answer : Plasma cell, short-lived antibody-producing cell derived from a type of leukocyte (white blood cell) called a B cell. B cells differentiate into plasma cells that produce antibody molecules closely ... production gradually decreases as the stimulus is removed (e.g., by recovery from infection)

Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies

Description : Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies

Last Answer : Answer : B

Proteins which are responsible for defence mechanism are called (A) Antimetabolites (B) Antibodies (C) Antimycins (D) Apoproteins

Description : Proteins which are responsible for defence mechanism are called (A) Antimetabolites (B) Antibodies (C) Antimycins (D) Apoproteins

Last Answer : Answer : B

The antibodies raised against a pure protein will show only one sharp spike on this technique: (A) Solubility curve (B) Solvent precipitation (C) Molecular weight determination (D) Immuno electrophoresis

Description : The antibodies raised against a pure protein will show only one sharp spike on this technique: (A) Solubility curve (B) Solvent precipitation (C) Molecular weight determination (D) Immuno electrophoresis

Last Answer : Answer : D

T cells can recognise (A) Free antigens (B) Antigens bound to cells (C) Antigens bound to antibodies (D) Antigens bound to MHC proteins

Description : T cells can recognise (A) Free antigens (B) Antigens bound to cells (C) Antigens bound to antibodies (D) Antigens bound to MHC proteins

Last Answer : Answer : D

Which of the following statement(s) is/are true concerning ischemia reperfusion injury? a. During ischemia, ATP degradation results in increased plasma and intracellular levels of hypoxanthine and xanthene b. Oxygen free radicals such as the superoxide radical are involved in the expression of the proinflammatory phenotype of endothelial cells, macrophages and neutrophils c. The intracellular adhesion molecule-1 (ICAN-1) contributes to injury and disruption of the endothelial lining, with extensive capillary leak and resultant interstitial edema d. Animal models have demonstrated that passive immunization with antibodies to neutrophil adhesive complex lessen the ischemic/reperfusion microvascular injury

Description : Which of the following statement(s) is/are true concerning ischemia reperfusion injury? a. During ischemia, ATP degradation results in increased plasma and intracellular levels of ... immunization with antibodies to neutrophil adhesive complex lessen the ischemic/reperfusion microvascular injury

Last Answer : Answer: a, b, c, d During the ischemia and hypoperfusion phase, degradation of ATP stores essential to maintain cell integrity and significant loss of diffusible ... either the neutrophil adhesive complex or the endothelial selectins dramatically lessens ischemia/reperfusion microvascular injury

Which of the following statement(s) is/are true concerning the antibody response to an invading antigen? a. All antibodies are composed of one type of heavy and one type of light protein chain b. The carboxyl terminus of the heavy chain is the antigen binding site c. Antibody of the immunoglobulin G class is the initial antibody produced in response to an antigenic stimulus d. Immunoglobulins A, D, and E play an active role in the circulating humoral response

Description : Which of the following statement(s) is/are true concerning the antibody response to an invading antigen? a. All antibodies are composed of one type of heavy and one type of light protein chain b. ... stimulus d. Immunoglobulins A, D, and E play an active role in the circulating humoral response

Last Answer : Answer: a Humoral defenses consist of antibody (immunoglobulin; Ig) and complement. All Ig classes (IgM, IgG, IgA, IgE, IgD) and IgG subclasses are composed of one type (M, G, A, E, D ... exist in smaller amounts in the circulation and do not appear to play a major role as host defense components

Which of the following statements regarding TNFa are true? a. TNFa has a marked procoagulant effect b. Passive immunization of patients with neutralizing antibodies to TNFa improves survival from multi-organ system failure c. TNFa upregulates E-selectin expression d. The most potent known stimulus for TNFa production and release is IL-1

Description : Which of the following statements regarding TNFa are true? a. TNFa has a marked procoagulant effect b. Passive immunization of patients with neutralizing antibodies to TNFa improves survival from multi-organ ... expression d. The most potent known stimulus for TNFa production and release is IL-1

Last Answer : Answer: a, c TNFa has a marked procoagulant effect on endothelial cells, precipitating intravascular thrombosis. TNFa causes endothelial cells to release procoagulant activity (tissue factor), ... to produce TNFa, however the most potent stimulus for TNFa production and release is endotoxin

Which of the following statements about septic shock are true? A. A circulating myocardial depressant factor may account for the cardiac dysfunction sometimes seen with shock due to sepsis or SIRS. B. A cardiac index (CI) of 6 liters per minute per square meter of body surface, a pulmonary capillary wedge pressure of 15 mm. Hg, and a systemic vascular resistance index (SVRI) of 800 dynes-sec/(cm 5-m 2) is a hemodynamic profile consistent with septic shock. C. An increase in SvO 2 in septic patients may be explained by the finding of anatomic arteriovenous shunts. D. Results of human trials employing antimediator therapy, such as antiendotoxin antibodies, IL-1 receptor antagonist, and tumor necrosis factor (TNF) antibodies, have confirmed animal studies that demonstrate a significant im

Description : Which of the following statements about septic shock are true? A. A circulating myocardial depressant factor may account for the cardiac dysfunction sometimes seen with shock due to sepsis or ... animal studies that demonstrate a significant improvement in survival with the use of such agents.

Last Answer : Answer: AB DISCUSSION: Shock due to sepsis or SIRS frequently manifests as a hyperdynamic cardiovascular response, consisting of an elevated CI and a decreased SVR or SVRI. Occasionally, ... been encouraging thus far in human clinical trials, despite the promising results from many animal studies

Which of the following is the drug of choice in treating suicidal overdose of digitoxin ? (a) Digoxin antibodies (b) Lidocaine (c) Magnesium (d) Potassium (e) Quinidine

Description : Which of the following is the drug of choice in treating suicidal overdose of digitoxin ? (a) Digoxin antibodies (b) Lidocaine (c) Magnesium (d) Potassium (e) Quinidine

Last Answer : Ans: A

If a fibrinolytic drug is used for treatment of acute myocardial infarction, the adverse drug effect that is most likely to occur is (a) Acute renal failure (b) Development of antiplatelet antibodies (c) Encephalitis secondary to liver dysfunction (d) Hemorrhagic stroke (e) Neutropenia

Description : If a fibrinolytic drug is used for treatment of acute myocardial infarction, the adverse drug effect that is most likely to occur is (a) Acute renal failure (b) Development of antiplatelet antibodies (c) Encephalitis secondary to liver dysfunction (d) Hemorrhagic stroke (e) Neutropenia

Last Answer : Ans: D

What are the enzymes used for labeling of antibodies ?

Description : What are the enzymes used for labeling of antibodies ?

Last Answer : Enzymes used for labeling of antibodies are horseradish peroxidase, alkaline phosphatase, ?- galactosidase, lacto preoxidase, etc.