Description : The drug, Interleukin-2, is an example of which type of biologic response modifier? a) Cytokine Other cytokines include interferon alfa and filgrastim. b) Monoclonal antibodies Monoclonal ... an example of a retinoid. d) Antimetabolites Antimetabolites are cell cycle-specific antineoplastic agents.
Last Answer : a) Cytokine Other cytokines include interferon alfa and filgrastim.
Description : The following is true of abciximab except: A. It is a monoclonal antibody against GPIIb/IIIa B. It inhibits platelet aggregation induced by a variety of platelet agonists C. It is antigenic D. It is used to reduce the risk of restenosis in patients undergoing PTCA
Last Answer : C. It is antigenic
Description : Which one of the following drugs is prescribed for the treatment of Philadelphia chromosome positive patients with Chronic myeloid Leukemia? (A) Pentostatin (B) Methotrexate (C) Imatinib (D) L-Asparaginase
Last Answer : (C) Imatinib
Description : What is the lifestyle like of someone with non Hodgkins lymphoma?
Last Answer : There is life after non-Hodgkin’s Lymphoma.
Description : Do you mind telling me everything you know about Non-Hodgkin's Lymphoma? If you or anyone you know has had it, please share your stories.
Last Answer : A niece was treated for it when she was in her 20s. Don’t know much about it but she is now in her 40s. She had a treatment that could possibly have rendered her infertile but went on to have three healthy children.
Description : Signs Of Non-Hodgkin's Lymphoma?
Last Answer : To understand cancer better, one must first understand the origin if it is identifiable. Cancers of the lymphatic system are best understood by knowing about that particular system and its function ... With proper, prompt treatment, this disease is manageable, and the prognosis is often favorable.
Description : Select the correc: combination of drugs for the treatment of patients suffering from Hepatitis C : (A) Interferon with Ribavirin (B) Interferon with Zidovudine (C) Interferon with Stavudine (D) Interferon with Lamivudine
Last Answer : (B) Interferon with Zidovudine
Description : Has any one have/had a friend with hodgkin's lymphoma stage 3? If so how did you deal with it?
Last Answer : answer:I want to show him he's still heathy just in other ways. Anyone have ideas of certain activities that are safe for Cancer patients? Careful. Your friend probably won't appreciate being dragged ... type of cancer, but through my own experiences with illness in general, I suspect I am right.
Description : Hodgkin's Lymphoma Symptoms?
Last Answer : Hodgkin's lymphoma is a cancer in the cells of the immune system. As the disease progresses, it attacks both the lymph vessels and the lymph fluid in the body. This leads to a host of symptoms ... are not often alarming, patients who have a family history of this disease should stay on the lookout.
Description : What are the symptoms and treatments for hodgkins lymphoma?
Last Answer : Symptoms of hodgkins lymphoma are fever and chills, constant itching, loss of appetite, night sweats, painless swelling of the lymph nodes (neck,armpits, and groin), and major weightloss. To ... the severity of the symptoms. The most wideley used methods of treatment are chemotherapy and radiation.
Description : Are there risk factors that up your chances for hodgkins lymphoma?
Last Answer : Those between the ages of 15 and 40 are most likely to get this disease. It is slightly more common in males and in those with a compromised immune system from HIV or AIDS.
Description : In patients with chronic granulomatous disease which of the following agents increases the synthesis of tumor necrosis factor, leading to activation of phagocytosis? (a) Aldesleukin (b) Cyclosporine (c) Filgrastim (d) Infliximab (e) Interferon gamma
Last Answer : Ans: E
Description : Are you hearing that people who won’t get vaccinated are instead getting monoclonal antibodies?
Last Answer : And the monoclonal antibodies don’t work that well anyway.
Description : Am I correct that people against fetal stem cell research are ok taking monoclonal antibodies?
Last Answer : I smell discreet advertisement… This is a tactics employed in my country when the antivax became a trend here. Vaccines are harmful, so buy our stuff instead!
Description : Assertion: The antibodies separated from serum are homogenous. Reason : Monoclonal antibodies are homogenous immunological reagents.
Last Answer : Assertion: The antibodies separated from serum are homogenous. Reason : Monoclonal antibodies are ... both the assertion and reason are false
Description : What medical conditions require the use of monoclonal antibodies?
Last Answer : Monoclonal antibodies work on specific cells. They are used in cancer treatment and in the treatment of autoimmune diseases.
Description : What diseases are being treated with monoclonal antibodies?
Last Answer : Uses for monoclonal antibodies include: Cancer Rheumatoid Arthritis Multiple sclerosis Cardiovascular disease Systemic lupus erythematosus Crohn's disease Ulcerative colitis Psoriasis
Description : What are monoclonal antibodies?
Last Answer : A type of protein made in the laboratory that can bind to substances in the body, including cancer cells. There are many kinds of monoclonal antibodies. A monoclonal antibody is made so that it ... They can be used alone or to carry drugs, toxins, or radioactive substances directly to cancer cells.
Description : Monoclonal antibodies are prepared by cloning (A) Myeloma cells (B) Hybridoma cells (C) T-Lymphocytes (D) B-Lymphocytes
Last Answer : Answer : B
Description : Antibodies produced by a single clone of myeloma cells are referred to as _____ antibodies. a. Chimeric b. Monoclonal c. Polyclonal d. Hybrid
Last Answer : b. Monoclonal
Description : A hybridoma cell a. Secretes monoclonal antibodies. b. Presents antigens on its surface. c. Secretes polyclonal antibodies. d. Is an antigen-presenting cell
Last Answer : d. Is an antigen-presenting cell
Description : Uses of monoclonal antibodies
Last Answer : 1) Monoclonal antibodies help in immunodiagnosis by detection of a particular antigen or antibody. 2) Many tumor-specific antibodies help in tumor detection. 3) Some of the monoclonal antibodies ... in the purification of cells in order to generate the info about their features and functions.
Description : Drugs in suspensions and semi-solid formulations always degrade by (A) first order kinetics (B)second order kinetics (C) zero order kinetics (D) non-linear kinetics
Last Answer : (C) zero order kinetics
Description : Drugs following one compartment open model pharmacokinetics eliminate (A) bi-exponentially (B) tri-exponentially (C) non-exponentially (D) mono-exponentially
Last Answer : (D) mono-exponentially
Description : The characteristic of non-linear pharmacokinetics include : (A) Area under the curve is proportional to the dose (B) Elimination half-life remains constant, (C) Area under the curve is not proportional to the dose (D) Amount of drug excreted through remains constant
Last Answer : (C) Area under the curve is not proportional to the dose
Description : Which of the following non-opioid analgesics is a prodrug? (A) Piroxicam (B) Celecoxib (C)Nabumetone (D) Ketorolac
Last Answer : (C)Nabumetone
Description : The following is true about use of prednisolone in malignant diseases except: A. It is curative in acute childhood leukaemia B. It is used in Hodgkin’s disease C. It controls hypercalcaemia in patients with bony metastasis D. It affords symptomatic relief in most cancer patients
Last Answer : A. It is curative in acute childhood leukaemia
Description : In which of the following techniques the sample is kept below triple point? (A) Lyophilization (B) Spray drying (C) Spray congealing (D) Centrifugation
Last Answer : (A) Lyophilization
Description : Which one of the following is NOT an ex-officio member of Pharmacy Council of India? (A) The Director General of Health Services (B) The Director of Central Drugs Laboratory (C) The Drugs Controller General of India (D) The Director of Pharmacopoeia Laboratory
Last Answer : (D) The Director of Pharmacopoeia Laboratory
Description : It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 hr and Vd of 5 L. The dose required in a sustained release product will be (A) 600 mg (B) 300 mg (C) 30 mg (D) 60 mg
Last Answer : (B) 300 mg
Description : The Volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be (A)10 L (B) 100 L (C) 1.0 L (D) 0.10 L
Last Answer : (A)10 L
Description : How many mL of a 1:500 w/v stock solution should be used to make 5 liters of 1:2000 w/v solution? (A) 750 mL (B) 1000 mL (c) 1250 mL (D) 1500 mL
Last Answer : (c) 1250 mL
Description : Class 100 area is referred to (A) Manufacturing area (B) Aseptic area (C) Clean room (D) Ware house
Last Answer : (B) Aseptic area
Description : Geriatric population should be included in the following Phase of clinical trials (A) Phase I (B) Phase II (C) Phase III (D) Phase
Last Answer : (B) Phase II
Description : A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is : (A) 125% (B) 250 % (C) 12.5% (D) 1.25%
Last Answer : (C) 12.5%
Description : Rabies vaccine (living) is prepared using (A) Sheep blood (B) Mice lymph (C) Horse plasma (D) Fertile eggs
Last Answer : (D) Fertile eggs
Description : In nail polish, following polymer is used as a film-former : (A) Nitrocellulose (B) Polylactic acid (C) Hydroxypropyl methylcellulose (D) Cellulose acetate phthalate
Last Answer : (A) Nitrocellulose
Description : The following protein/polypeptide has a quaternary structure : (A) cc-Chymotrypsin (B) Hemoglobin (C) Insulin (D) Myoglobin
Last Answer : (B) Hemoglobin
Description : Many xenobiotics are oxidized by cytochrome P450 in order to (A) increase their biological activity (B) increase their disposition in lipophilic compartments of the body (C) increase their aqueous solubility (D) all of the above
Last Answer : (D) all of the above
Description : The temperature condition for storage of drug products under cold temperature is given as : (A) temperature between 8°C and 25°C (B) temperature below 20 C (C) temperature at 0°C (D) temperature between 2c C and S: C
Last Answer : (D) temperature between 2c C and S: C
Description : Coulter counter is used in determination of (A) particle surface area (B) particle size (C) particle volume (D)all of A, B, C
Last Answer : (D)all of A, B, C
Description : Oxidative phosphorylation involves (A) Electron transport system (B) Substrate level phosphorylation (C) Reaction catalyzed by succinic thiokinase in TCA cycle (D) None of the above
Last Answer : (A) Electron transport system
Description : In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their (A) volatility (B) solubility (C)thermal conductivity (D) polarizability
Last Answer : (D) polarizability
Description : Glass transition temperature is detected through (A) X-Ray diffractometery (B) Solution calorimetery (C) Differential scanning calorimetery (D) Thermogravimetric analysis
Last Answer : (C) Differential scanning calorimetery
Description : In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than (A) 350 nm (B) 200 nm (C) 300 nm (D) 250 nm
Last Answer : (A) 350 nm
Description : Streptomycin can NOT be given orally for treatment of tuberculosis because (A) it gets degraded in the GIT (B) it causes severe diarrhoea (C) it causes metallic taste in the mouth (D) it is not absorbed from the GIT
Last Answer : (D) it is not absorbed from the GIT
Description : In thiazides following substituent is essential for diuretic activity : (A) Chloro group at position 6 (B) Methyl group at position 2 (C) Sulphamoyl group at position 7 (D) Hydrophobic group at position 3
Last Answer : (C) Sulphamoyl group at position 7
Description : One of the following statements is NOT true : (A) Accuracy expresses the correctness of measurement (B) Precision represents reproducibility of measurement (C) High degree of precision implies high degree of accuracy also (D) High degree of accuracy implies high degree of precesion also
Last Answer : (C) High degree of precision implies high degree of accuracy also
Description : Indicate the HPLC detector that is most sensitive to change in temperature : (A) PDA detector (B) Refractive Index detector (C) Electrochemical detector (D) Fluorescence detector
Last Answer : (B) Refractive Index detector
Description : Artemisinin contains the following group in its structure : (A) an endoperoxide (B) an exoperoxide (C) an epoxide (D) an acid hydrazide
Last Answer : (A) an endoperoxide