Low Platelet Count: Treatment?

Low Platelet Count: Treatment?
by

1 Answer

Answer :

When a person has a low platelet count, this means that the blood does not have enough platelets, or thrombocytes, to help them clot the blood in order to heal wounds. Another term for the condition is known as thrombocytopenia, and depending on the amount of platelets and the reason the condition exists, it can either be mild or extremely dangerous. The cause and the severity of the illness will also ultimately determine what course of treatment will be taken. Low platelet count can occur due to a number of natural reasons, such as pregnancy and other similar conditions. Normally, a reduction in the amount of platelets that a person has is not a cause for concern, so doctors do not treat it when the reduction is mild, instead using the wait and watch approach to see what happens. Thrombocytopenia caused by pregnancy will usually result in a normal recovery without worry. Children will also have an easier time recovering from the condition due to their young marrow being able to quickly produce platelets. In other situations, however, medications are needed to treat a low platelet count, especially with the instance of ITP, where the body mistakenly considers platelets to be a foreign substance in the body, causing it to attack the platelets and destroy them. Medications can cause this stance as well. In these cases, doctors will provide medications to disable the auto-immune response to destroying the platelets. Treating ITP can also include removing the spleen, which can be greatly encouraging the response to destroying the thrombocytes. One of the primary approaches to treating this condition includes blood or platelet transfusions, with both potentially being necessary. When a person experiences very low platelet counts, there can be internal bleeding, meaning blood must be replaced. Transmitting more platelets would also be a good preventative to keep internal bleeding from occurring. Due to the risk of low platelet count with cancer, patients who are also undergoing the treatment of cancer will also often have to include platelet transfusions in their course of treatment to prevent internal bleeding and other complications from chronic low platelet count and similar problems.
by

Related questions

Which of the following statement(s) concerning laboratory studies used in monitoring a patient with intravenous heparinization is/are correct? a. The platelet count should be followed because of the risk of heparin-associated thrombocytopenia b. The prothrombin time should be observed if prolonged treatment is necessary c. The activated partial thromboplastin time (aPTT) should be maintained at approximately 1.5 times normal d. The serum creatinine should be measured daily to allow adjustments in dose based on renal function

Description : Which of the following statement(s) concerning laboratory studies used in monitoring a patient with intravenous heparinization is/are correct? a. The platelet count should be followed because of the ... serum creatinine should be measured daily to allow adjustments in dose based on renal function

Last Answer : Answer: a, c In monitoring the effect of heparin, an activated partial thromboplastin time (aPTT) of 1.5 control or a thrombin clotting time (TCT) of 2 times control reflects adequate ... system. Therefore the dose of heparin need not be adjusted in cases of liver or renal dysfunction

What is the reason for a low platelet count?

Description : What is the reason for a low platelet count?

Last Answer : There are many reasons for a low platelet count, or Thrombocytopenia. Perhaps your body has decided to not produce as much, or maybe they are trapped in an organ. There could also be an increased amount of damage to them, causing your body to not be able to keep up producing them.

What does a low blood platelet count mean - Topix?

Description : What does a low blood platelet count mean - Topix?

Last Answer : This is called Thrombocytopenia and means that the body is low on platelets, a type of blood cell that helps your blood to clot when damage occurs to blood vessels. Depending on ... the platelet count is, individuals with Thrombocytopenia may bruise easily and experience nosebleeds or bleeding gums.

What happens when you have a low platelet count?

Description : What happens when you have a low platelet count?

Last Answer : Depending of the severity it may simply mean that you bruise more easily than most, however a low platelet count can also be a sight of hemophilia which means that you blood finds it hard to ... of spontaneous bleeding which can be very serious. You need to discuss this further with your doctor.

What factors lead to a low platelet count?

Description : What factors lead to a low platelet count?

Last Answer : No, it does not mean these issues are related because having a low platelet count can mean many diseases, sicknesses, and illnesses. I advise you to seek a doctor to find out.

What is a really low platelet count?

Description : What is a really low platelet count?

Last Answer : A low platelet count, called thrombocytopenia, causes the blood to fail to clot easily. A healthy platelet count should be between 150,000 and 450,000 platelets per micro liter of blood. A level lower than 150,000 platelets indicates thrombocytopenia.

Important Information Needed to Understand Low Platelet Count?

Description : Important Information Needed to Understand Low Platelet Count?

Last Answer : In the most simplistic terms, platelets are the cells in your blood stream that have the function of promoting clotting. These platelets must exist in the blood stream in large numbers. If the ... but with certain illnesses, the spleen may be removing platelets too soon, causing low platelet counts.

Critical count of Platelet is `:-`

Description : Critical count of Platelet is `:-`

Last Answer : Critical count of Platelet is `:-` A. `40,000//m m^(3)` B. 1 lac `// m m^(3)` C. 2 lac `// m m^(3)` D. 4 lac `// m m^(3)`

What are the Complications of below platelet count?

Description : What are the Complications of below platelet count?

Last Answer : Feel Free to Answer

After giving blood, how long does it take for the platelet count to return to normal?

Description : After giving blood, how long does it take for the platelet count to return to normal?

Last Answer : If you give blood it really doesn't take long for your platelet to get back. It really just takes a few miniatures depending upon your body weight.

Platelet count?

Description : Platelet count?

Last Answer : DefinitionA platelet count is a test to measure how many platelets you have in your blood. Platelets help the blood clot. They are smaller than red or white blood cells.Alternative NamesThrombocyte countHow ... the blood has been collected, the needle is removed, and the puncture site is covered to

Laboratory monitoring of coagulation and anticoagulation includes testing of platelet function. Which of the following statements is/are true concerning tests of platelet function? a. A platelet count of 50,000/µL or more usually ensures hemostasis b. Bleeding time assays assessibility of platelets to perform hemostatic plugs and is determined from a sample of blood drawn in an EDTA coated test tube c. Aspirin therapy can be associated with a bleeding time in the range of 8–15 minutes d. Tests of platelet aggregation should be part of the standard preoperative evaluation of patients using aspirin

Description : Laboratory monitoring of coagulation and anticoagulation includes testing of platelet function. Which of the following statements is/are true concerning tests of platelet function? a. A ... platelet aggregation should be part of the standard preoperative evaluation of patients using aspirin

Last Answer : Answer: a, c Tests of platelet function include peripheral platelet counts, bleeding times, and platelet aggregation. Usually, a platelet count of 50,000/mL or more ensures adequate hemostasis ... is not available in most laboratories, probably because of the observer-dependent nature of the test

A 67-year-old male with advanced cholangiocarcinoma develops gram-negative sepsis. Excessive bleeding is noted around vascular catheters and from needle puncture sites. The diagnosis of disseminated intervascular coagulation (DIC) is considered. Which of the following laboratory test(s) is/are indicative of DIC? a. Decreased platelet count b. Decreased fibrinogen level c. Normal prothrombin time d. Elevated fibrin split products

Description : A 67-year-old male with advanced cholangiocarcinoma develops gram-negative sepsis. Excessive bleeding is noted around vascular catheters and from needle puncture sites. The diagnosis of disseminated ... b. Decreased fibrinogen level c. Normal prothrombin time d. Elevated fibrin split products

Last Answer : Answer: a, b, d Disseminated intravascular coagulation (DIC) is the primary form of acute thrombosis. Causes of this syndrome include abruptio placenta, gram-positive and gram-negative sepsis, ... decline in the platelet count and fibrinogen level, along with an elevation of fibrin split products

Which of the following statement(s) is/are true concerning heparin-associated thrombocytopenia? a. Heparin-associated thrombocytopenia occurs only in the face of over anticoagulation with heparin b. Severe thrombocytopenia (platelet count less than 100,000) is seen in less than 10% of patients treated with heparin c. Heparin-associated thrombocytopenia is due to the aggregation of platelets and may result in thrombosis or embolic episodes d. Heparin-associated thrombocytopenia may be seen within hours of initiation of heparin therapy

Description : Which of the following statement(s) is/are true concerning heparin-associated thrombocytopenia? a. Heparin-associated thrombocytopenia occurs only in the face of over anticoagulation with heparin b. ... d. Heparin-associated thrombocytopenia may be seen within hours of initiation of heparin therapy

Last Answer : Answer: b, c Heparin-associated thrombocytopenia occurs in 0.6% to 30% of patients who receive heparin, although severe thrombocytopenia (platelet counts less than 100,000) is seen in ... as coating on pulmonary artery catheters or low rate infusion into arterial catheters may cause this syndrome

The evaluation of a patient scheduled for elective surgery should always include the following as tests of hemostasis and coagulation: A. History and physical examination. B. Complete blood count (CBC), including platelet count. C. Prothrombin time (PT) and activated partial thromboplastin time (APTT). D. Studies of platelet aggregation with adenosine diphosphate (ADP) and epinephrine.

Description : The evaluation of a patient scheduled for elective surgery should always include the following as tests of hemostasis and coagulation: A. History and physical examination. B. Complete blood count ( ... (APTT). D. Studies of platelet aggregation with adenosine diphosphate (ADP) and epinephrine.

Last Answer : Answer: A DISCUSSION: The evaluation of most patients scheduled for elective surgery who do not have a history of significant bleeding disorders is somewhat controversial. An adequate history and ... suspected of having qualitative defects of platelet function (e.g., von Willebrand's disease)

In 70 kg patient one unit of platelet concentrate should increase platelet count A. 2000 - 5000 mm3 B. 5000 - 10000 mm3 C. 10000 - 20000 mm3 D. More than 20000 mm3

Description : In 70 kg patient one unit of platelet concentrate should increase platelet count A. 2000 - 5000 mm3 B. 5000 - 10000 mm3 C. 10000 - 20000 mm3 D. More than 20000 mm3

Last Answer : Ans: B

Which of the following terms refers to an abnormal decrease in white blood cells, red blood cells, and platelets? a) Pancytopenia Pancytopenia may be congenital or acquired. b) Anemia Anemia refers to decreased red cell mass. c) Leukopenia Leukopenia refers to a less-than-normal amount of WBCs in circulation. d) Thrombocytopenia Thrombocytopenia refers to a lower-than-normal platelet count.

Description : Which of the following terms refers to an abnormal decrease in white blood cells, red blood cells, and platelets? a) Pancytopenia Pancytopenia may be congenital or acquired. b) Anemia ... of WBCs in circulation. d) Thrombocytopenia Thrombocytopenia refers to a lower-than-normal platelet count.

Last Answer : a) Pancytopenia Pancytopenia may be congenital or acquired.

The patient whom you are about to treat states that he has Von Willebrand’s disease. Which one of the following preoperative haematological analyses may reflect this disease: A. Bleeding time and factor VIII level ptt also prolonged decreased platelet count. B. Bleeding time and factor IX level C. Bleeding time and factor X level D. Platelet count E. Thromboplastin generation time

Description : The patient whom you are about to treat states that he has Von Willebrand's disease. Which one of the following preoperative haematological analyses may reflect this disease: A. Bleeding time and ... C. Bleeding time and factor X level D. Platelet count E. Thromboplastin generation time

Last Answer : A. Bleeding time and factor VIII level ptt also prolonged decreased platelet count

Which cell count tends to be elevated when an individual has an allergy or parasitic worms? a) red blood cells b) erythrocyte c) eosinophil (pron: e-o-sin-o-fill) d) platelet

Description : Which cell count tends to be elevated when an individual has an allergy or parasitic worms? a) red blood cells b) erythrocyte c) eosinophil (pron: e-o-sin-o-fill) d) platelet

Last Answer : ANSWER: C -- eosinophil

What is the characteristic feature of gingivitis in AIDS patient:** A. Red band on the free gingiva associated with platelet. B. Correlating with other pathogenesic lesions of AIDS and does not resolve to periodontal conventional treatment. C. Sever pain

Description : What is the characteristic feature of gingivitis in AIDS patient:**  A. Red band on the free gingiva associated with platelet.   B. Correlating with other pathogenesic lesions of AIDS and does not resolve to periodontal  conventional treatment.  C. Sever pain 

Last Answer : A. Red band on the free gingiva associated with platelet.  

Mini-dose heparin has been shown to be useful in the prophylaxis of postoperative venous thrombosis. Mechanism(s) by which low-dose heparin is/are thought to protect against venous thrombosis include: a. Enhancement of antithrombin III activity b. A decrease in thrombin availability c. Inhibition of platelet aggregation and subsequent platelet release action d. A mild prolongation of activated partial thromboplastin time

Description : Mini-dose heparin has been shown to be useful in the prophylaxis of postoperative venous thrombosis. Mechanism(s) by which low-dose heparin is/are thought to protect against venous ... aggregation and subsequent platelet release action d. A mild prolongation of activated partial thromboplastin time

Last Answer : Answer: a, b, c Low-dose heparin is thought to protect against venous thrombosis through three different mechanisms. First, antithrombin III activity with its inhibition of activated Factor X is ... release reaction. The standard doses of heparin administered (5000 units bid) does not affect aPTT

Aspirin in low doses produces longlasting inhibition (a) Platelets contain low quantity of COX (b) Platelets cannot synthesize fresh COX molecules (c) Platelets bind aspirin with high affinity (d) Platelet COX is inducible

Description : Aspirin in low doses produces longlasting inhibition (a) Platelets contain low quantity of COX (b) Platelets cannot synthesize fresh COX molecules (c) Platelets bind aspirin with high affinity (d) Platelet COX is inducible

Last Answer : Ans: B

Aspirin in low doses produces longlasting inhibition of platelet cyclooxygenase (COX) because: A. Platelets contain low quantity of COX B. Platelets cannot synthesize fresh COX molecules C. Platelets bind aspirin with high affinity D. Platelet COX is inducible

Description : Aspirin in low doses produces longlasting inhibition of platelet cyclooxygenase (COX) because: A. Platelets contain low quantity of COX B. Platelets cannot synthesize fresh COX molecules C. Platelets bind aspirin with high affinity D. Platelet COX is inducible

Last Answer : B. Platelets cannot synthesize fresh COX molecules

Low doses of aspirin prolong bleeding time by selectively inhibiting synthesis of the following mediator in the platelets: A. Thromboxane A2 B. 5-Hydroxytryptamine C. Platelet activating factor D. Prostacyclin

Description : Low doses of aspirin prolong bleeding time by selectively inhibiting synthesis of the following mediator in the platelets: A. Thromboxane A2 B. 5-Hydroxytryptamine C. Platelet activating factor D. Prostacyclin

Last Answer : A. Thromboxane

What is the thread count on the Concord Window Treatment Tie-Up Balloon Shade?

Description : What is the thread count on the Concord Window Treatment Tie-Up Balloon Shade?

Last Answer : I think the thread count is just 200.

Which of the following statements reflect the treatment of HIV infection? a) Treatment of HIV infection for an individual patient is based on the clinical condition of the patient, CD4 T cell count level, and HIV RNA (viral load). Although specific therapies vary, treatment of HIV infection for an individual patient is based on three factors: the clinical condition of the patient, CD4 T cell count level, and HIV RNA (viral load).

Description : Which of the following statements reflect the treatment of HIV infection? a) Treatment of HIV infection for an individual patient is based on the clinical condition of the patient, CD4 T cell count level, and ... CD4+ T cells/mm3 or plasma HIV RNA levels exceeding 55,000 copies/mL (RT-PCR assay).

Last Answer : a) Treatment of HIV infection for an individual patient is based on the clinical condition of the patient, CD4 T cell count level, and HIV RNA (viral load). Although specific therapies vary, treatment of ... : the clinical condition of the patient, CD4 T cell count level, and HIV RNA (viral load).

A patient on dicoumarol treatment needs extraction. Which of the following is MOST valuable in evaluating surgical risks: A. Clotting time B. Bleeding time C. Prothrombin time D. Sedimentation rate E. Complete blood cell count

Description : A patient on dicoumarol treatment needs extraction. Which of the following is MOST valuable in evaluating surgical risks: A. Clotting time B. Bleeding time C. Prothrombin time D. Sedimentation rate E. Complete blood cell count

Last Answer : C. Prothrombin time

If the count of Echinochloa in weedy check is 70 and that in a treatment 25/m2, weed control efficiency will be a). 54.3% b). 64.3% c). 73.4% d). 79.6%

Description : If the count of Echinochloa in weedy check is 70 and that in a treatment 25/m2, weed control efficiency will be a). 54.3% b). 64.3% c). 73.4% d). 79.6%

Last Answer : b). 64.3%

Antiretroviral treatment affords the following benefit(s) in HIV infection: A. Increases CD4 leucocyte count B. Reduces the incidence of opportunistic infections in AIDS patients C. Increases survival time in AIDS patients D. All of the above

Description : Antiretroviral treatment affords the following benefit(s) in HIV infection: A. Increases CD4 leucocyte count B. Reduces the incidence of opportunistic infections in AIDS patients C. Increases survival time in AIDS patients D. All of the above

Last Answer : D. All of the above

Does frequent blood/platelet donation harm your veins?

Description : Does frequent blood/platelet donation harm your veins?

Last Answer : answer:No, because you're not putting anything other than blood and saline back in. From what I understand, it's pushing something into your vein that is not normally full strength in the blood ... her vein. That's because of the strength of the cocktail interacting with the walls of the vein.

What is Platelet ?

Description : What is Platelet ?

Last Answer : : The nucleus is called platelet. They can be round oval or rod shaped.

What are my platelet counts with Leukemia?

Description : What are my platelet counts with Leukemia?

Last Answer : Need answer

What protein forms a bridge between exposed vessel wall collagen and platelet surface receptors?

Description : What protein forms a bridge between exposed vessel wall collagen and platelet surface receptors?

Last Answer : Need answer

Platelet associated antibodies?

Description : Platelet associated antibodies?

Last Answer : DefinitionA test for platelet-associated antibodies shows whether you have antibodies that are directed against platelets in your blood.How the test is performedBlood is typically drawn from a vein, usually from ... site is covered to stop any bleeding.In infants or young children, a sharp tool call

What is Platelet-Rich Plasma (PRP) and What are PRP Injections?

Description : What is Platelet-Rich Plasma (PRP) and What are PRP Injections?

Last Answer : Platelet-rich plasma (PRP) therapy employs injections of a concentration of a patient’s own platelets to optimize the healing of injured tendons, ligaments, muscles, and joints. Through this ... generates growth factors that induce and strengthen the number of reparative cells the body produces.

One of the important functions of prostacyclins is (A) Inhibition of platelet aggregation (B) Contraction of uterus (C) Decrease of gastric secretion (D) Relieving osthma

Description : One of the important functions of prostacyclins is (A) Inhibition of platelet aggregation (B) Contraction of uterus (C) Decrease of gastric secretion (D) Relieving osthma

Last Answer : Answer : A

Prostaglandins decrease all of the following except (A) Gastric acid secretion (B) Blood pressure (C) Uterine contraction (D) Platelet aggregation

Description : Prostaglandins decrease all of the following except (A) Gastric acid secretion (B) Blood pressure (C) Uterine contraction (D) Platelet aggregation

Last Answer : Answer : C

Dipalmitoyl lecithin acts as (A) Platelet activating factor (B) Second messenger for hormones (C) Lung surfactant (D) Anti-ketogenic compound

Description : Dipalmitoyl lecithin acts as (A) Platelet activating factor (B) Second messenger for hormones (C) Lung surfactant (D) Anti-ketogenic compound

Last Answer : Answer : C

Thromboxanes cause (A) Vasodilation (B) Bronchoconstriction (C) Platelet aggregation (D) All of these

Description : Thromboxanes cause (A) Vasodilation (B) Bronchoconstriction (C) Platelet aggregation (D) All of these

Last Answer : Answer : C

Which of the following statement(s) is/are correct concerning the immunoinflammatory response to shock? a. The anaphylactoxins, C3a and C5a, are products of activation of only the classical pathway of the compliment cascade b. Eicosanoids, such as prostaglandins are stored in platelets and endothelial cells and released in response to inflammatory stimuli c. Thromboxane and PGI2 have similar effects d. Platelet-activating factor can be released by both circulating and fixed tissue cells

Description : Which of the following statement(s) is/are correct concerning the immunoinflammatory response to shock? a. The anaphylactoxins, C3a and C5a, are products of activation of only the classical pathway ... effects d. Platelet-activating factor can be released by both circulating and fixed tissue cells

Last Answer : Answer: d Inflammatory mediators have recently been recognized as playing a significant role in the clinical manifestations and progression of shock and the development ... increased pulmonary vascular resistance, bronchoconstriction, peripheral vasodilatation, and increased vascular permeability

Platelet activating factor is: a. Generated by the action of phospholipase A2 on membrane phospholipids b. Antiinflammatory in most of its actions c. Synthesized by endothelial and other cells d. Exerts a variety of biologic effects which are platelet-independent

Description : Platelet activating factor is: a. Generated by the action of phospholipase A2 on membrane phospholipids b. Antiinflammatory in most of its actions c. Synthesized by endothelial and other cells d. Exerts a variety of biologic effects which are platelet-independent

Last Answer : Answer: a, c, d Like the eicosanoids, platelet-activating factor (PAF) is not stored in cells but is rapidly produced during inflammation. PAF exerts a variety of biologic effects ... and LTB4. There is considerable overlap and redundancy in the effects produced by PAF and eicosanoids

Cytokines with clearly defined actions in acute inflammation and early tissue injury include which of the following? a. Cysteine-X-Cysteine (C-X-C) chemokines b. Tumor Necrosis Factor (TNFa) c. Transforming Growth Factor-b (TGF-b) d. Interleukin-6 (IL-6) e. Platelet Derived Growth Factor (PDGF)

Description : Cytokines with clearly defined actions in acute inflammation and early tissue injury include which of the following? a. Cysteine-X-Cysteine (C-X-C) chemokines b. Tumor Necrosis Factor (TNFa) c. Transforming Growth Factor-b (TGF-b) d. Interleukin-6 (IL-6) e. Platelet Derived Growth Factor (PDGF)

Last Answer : Answer: a, b, c, d, e Polypeptide mediators, such as TNFa and IL-1, are considered early response cytokines and are actively involved in the initiation of the ... of tissue repair. Thus, coagulation and platelet activation provide the initial foundation for subsequent cellular recruitment

Which of the following substances, not normally present in the circulation, trigger the initiating events in the hemostatic process? a. Thrombin b. Platelet factor 3 c. Tissue factor d. Collagen

Description : Which of the following substances, not normally present in the circulation, trigger the initiating events in the hemostatic process? a. Thrombin b. Platelet factor 3 c. Tissue factor d. Collagen

Last Answer : Answer: c, d The initiating agents for hemostasis involve two substances that are not normally present in the circulation-collagen and tissue factor. Tissue factor is released from ... phospholipid surface to form the so-called prothrombinase complex which catalyzes the formation of thrombin

Which of the following statement(s) is/are true concerning hemophilia A? a. Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII b. A positive family history for bleeding disorders present in all patients c. Laboratory tests reveal a prolongation of aPTT, prothrombin time (PT), thrombin clotting time and platelet aggregation d. Spontaneous bleeding is unusual with factor VIII levels greater than 10% of normal

Description : Which of the following statement(s) is/are true concerning hemophilia A? a. Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII b. A positive family history for ... platelet aggregation d. Spontaneous bleeding is unusual with factor VIII levels greater than 10% of normal

Last Answer : Answer: a, d Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII although 0% of cases are secondary to spontaneous mutation. The incidence of this abnormality is ... factor levels as low as 1% have been noted and patients are at risk for spontaneous bleeding

Which of the following statement(s) is/are true concerning pharmacologic agents used to accelerate wound healing? a. A number of these agents are now currently approved for use in this country b. PDGF (platelet-derived growth factor) promotes fibroblast proliferation, chemotaxis, and collagenase synthesis c. PDGF has been demonstrated in a number of clinical trials to promote healing in chronic wounds d. Growth hormone functions by promoting fibroblast proliferation and collagen synthesis

Description : Which of the following statement(s) is/are true concerning pharmacologic agents used to accelerate wound healing? a. A number of these agents are now currently approved for use in ... healing in chronic wounds d. Growth hormone functions by promoting fibroblast proliferation and collagen synthesis

Last Answer : Answer: b, c Currently there are no approved clinical agents that accelerate normal healing. Although a number of clinical trials are in progress, no agents are currently ... hormone administration significantly accelerates donor site healing, presumably due to its effects in minimizing catabolism

Products of platelet degranulation include: a. Tumor necrosis factor b. Interleukin-1 c. Transforming growth factor b d. Platelet-derived growth factor

Description : Products of platelet degranulation include: a. Tumor necrosis factor b. Interleukin-1 c. Transforming growth factor b d. Platelet-derived growth factor

Last Answer : Answer: c, d The initial response to injury and disruption of a blood vessel is bleeding. The hemostatic response to this is clot formation to stop hemorrhage. Platelet plug ... . Tumor necrosis factor and interleukin-1 also stimulate fibroblast proliferation, however are produced by macrophages

Which of the following cell types are not crucial for healing a clean, incisional wound? A. Macrophage. B. Platelet. C. Fibroblast. D. Polymorphonuclear leukocyte. E. Myofibroblast.

Description : Which of the following cell types are not crucial for healing a clean, incisional wound? A. Macrophage. B. Platelet. C. Fibroblast. D. Polymorphonuclear leukocyte. E. Myofibroblast.

Last Answer : Answer: DE DISCUSSION: Experimental studies have shown that healing may progress normally in the absence of polymorphonuclear leukocytes in an uninfected wound. In contrast, depletion of monocytes and ... wound contraction in open defects but have little if any role in clean, incisional wounds

True statements regarding eicosanoids include which of the following? A. Prostaglandins and thromboxanes are synthesized via the cyclo-oxygenase pathway. B. The vasoconstricting, platelet-aggregating, and bronchoconstricting effects of thromboxane A 2 are balanced by the actions of prostacyclin, which produces the opposite effects. C. Leukotriene synthesis is inhibited by the action of nonsteroidal anti-inflammatory drugs (NSAIDs). D. The principal prostaglandins have a short circulation half-life and exert most of their effects locally.

Description : True statements regarding eicosanoids include which of the following? A. Prostaglandins and thromboxanes are synthesized via the cyclo-oxygenase pathway. B. The vasoconstricting, platelet-aggregating, ... prostaglandins have a short circulation half-life and exert most of their effects locally.

Last Answer : Answer: ABD DISCUSSION: The eicosanoids are a group of compounds arising from the metabolism of arachidonic acid. The prostaglandins and thromboxanes are synthesized via the cyclo-oxygenase ... effects and may be involved in the physiologic responses associated with anaphylactic and septic shock

Which of the following statements regarding cytokines is incorrect? A. Cytokines act directly on target cells and may potentiate the actions of one another. B. Interleukin 1 (IL-1) is a major proinflammatory mediator with multiple effects, including regulation of skeletal muscle proteolysis in patients with sepsis or significant injury. C. Platelet-activating factor (PAF) is a major cytokine that results in platelet aggregation, bronchoconstriction, and increased vascular permeability. D. Tumor necrosis factor alpha (TNF-a), despite its short plasma half-life, appears to be a principal mediator in the evolution of sepsis and the multiple organ dysfunction syndrome because of its multiple actions and the secondary cascades that it stimulates.

Description : Which of the following statements regarding cytokines is incorrect? A. Cytokines act directly on target cells and may potentiate the actions of one another. B. Interleukin 1 (IL-1) ... organ dysfunction syndrome because of its multiple actions and the secondary cascades that it stimulates.

Last Answer : Answer: C DISCUSSION: Cytokines are soluble peptide molecules that are synthesized and secreted by a number of cell types in response to injury, inflammation, and infection. Cytokines, which ... is thought to play a central role in the stress response, particularly in response to endotoxemia

The action of 5-Hydroxy tryptamine mediated by the 5-HT3 receptor is (a) Vasoconstriction (b) Bradycardia (c) EDRF release (d) Platelet aggregation

Description : The action of 5-Hydroxy tryptamine mediated by the 5-HT3 receptor is (a) Vasoconstriction (b) Bradycardia (c) EDRF release (d) Platelet aggregation

Last Answer : Ans: B