Advil contains ibuprofen which can have some major side effects if taken too long. Furthermore, you shouldn't be taking this more than twice a day or two tablets every 6 to 8 hours. If you take this over a long period of time you risk the chance of: Stomachaches Heartburn Dizziness Rash Drowsiness Nausea Vomiting Constipation Ringing in your ears Over a long period of time you will have other medical problems that could lead to or cause: Liver failure or inflammation in the liver Low platelet count Blood in your urine Stroke Heart attacks Sever or life-threatening skin reactions Blood pressure Kidney damage If you are looking for a painkiller to help ease the pain don't take this more than a few days before switching over to Tylenol or another type of painkiller that doesn't have ibuprofen in it. Furthermore, if you are taking this for a long-time and have any of the symptoms listed above, then you need to see a doctor immediately. This isn't safe to take for an extended period of time. Most doctors will tell you to limit this or stop taking it after 5 to 7 days and won't advise you to continue taking this after that time frame.