Description : The antidotal action of sodium nitrite in cyanide poisoning is based on: A. Physical antagonism B. Chemical antagonism C. Physiological antagonism D. Noncompetitive antagonism
Last Answer : B. Chemical antagonism
Description : The antidotal effect of sodium nitrite in cyanide poisoning is dependent upon: A. Chemical combination of sodium nitrite with cyanide B. Vasodilatation caused by sodium nitrite C. ... haemoglobin to methaemoglobin by sodium nitrite D. Facilitation of cyanocobalamine formation by sodium nitrite
Last Answer : C. Conversion of haemoglobin to methaemoglobin by sodium nitrite
Description : A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a: A. Physiological antagonist B. Competitive antagonist C. Noncompetitive antagonist D. Partial agonist
Last Answer : C. Noncompetitive antagonist
Description : The antagonism between adrenaline and histamine is called ‘physiological antagonism’ because: A. Both are physiologically present in the body B. They act on physiological receptors C. Both affect many physiological processes D. They have opposite physiological effects
Last Answer : D. They have opposite physiological effects
Description : Which of the following drug can result in result in cyanide poisoning? A. Amyl nitrite B. Hydroxycobalamine C. Sodium nitroprusside D. Sodium thiosulphate
Last Answer : C. Sodium nitroprusside
Description : Drugs acting through receptors exhibit the following features except: A. Structural specificity B. High potency C. Competitive antagonism D. Dependence of action on lipophilicity
Last Answer : D. Dependence of action on lipophilicity
Description : Which of the following terms best describes the antagonism of leukotriene's bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with ... ) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist
Last Answer : Ans: C
Description : The following is a competitive antagonist of GABA but a noncompetitive antagonist of diazepam: A. Picrotoxin B. Muscimol C. Flumazenil D. Bicuculline
Last Answer : D. Bicuculline
Description : A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a: A. Partial agonist B. Inverse agonist C. Competitive antagonist D. Noncompetitive antagonist
Last Answer : C. Competitive antagonist
Description : The following statement is not true of log dose-response curve: A. It is almost linear except at the ends B. It is a rectangular hyperbola C. It facilitates comparison of different agonists D. It can help in discriminating between competitive and noncompetitive antagonists
Last Answer : B. It is a rectangular hyperbola
Description : If the effect of combination of two drugs is equal to the sum of their individual effects, the two drugs are exhibiting: A. Potentiation B. Synergism C. Cross tolerance D. Antagonism
Last Answer : B. Synergism
Description : The following attribute of a drug tends to reduce its volume of distribution: A. High lipid solubility B. Low ionisation at physiological pH values C. High plasma protein binding D. High tissue binding
Last Answer : C. High plasma protein binding
Description : The dose of the following class of drugs has to be adjusted by repeated measurement of the affected physiological parameter: A. Oral contraceptives B. Antiepileptics C. Antidepressants D. Oral anticoagulants
Last Answer : D. Oral anticoagulants
Description : The following statement is true in relation to drug toxicity' and poisoning': A. The two terms are synonymous B. When a toxic effect requires specific treatment, it is called poisoning C. ... is called poisoning D. Toxicity is caused by drugs while poisoning is caused by other harmful chemicals
Last Answer : C. A toxic effect which endangers life by markedly affecting vital functions is called poisoning
Description : The following is a proven human teratogen: A. Chloroquine B. Warfarin sodium C. Dicyclomine D. Methyldopa
Last Answer : B. Warfarin sodium
Description : Which of the following is a weakly acidic drug: A. Atropine sulfate B. Chloroquine phosphate C. Ephedrine hydrochloride D. Phenytoin sodium
Last Answer : D. Phenytoin sodium
Description : Which of the following drugs is most likely to be absorbed from the stomach: A. Morphine sulfate B. Diclofenac sodium C. Hyoscine hydrobromide D. Quinine dihydrochloride
Last Answer : B. Diclofenac sodium
Description : A drug which produces qualitatively different actions when administered through different routes is: A. Phenytoin sodium B. Hydralazine C. Magnesium sulfate D. Nitroglycerine
Last Answer : C. Magnesium sulfate
Description : What is the chemical name for `Baking Soda'? (1) Sodium carbonate (2) Sodium bicarbonate (3) Sodium nitrite (4) Sodium nitrate
Last Answer : (2) Sodium bicarbonate Explanation: Sodium bicarbonate or sodium hydrogen carbonate is the chemical compound with the formula NaHCO3. Sodium bicarbonate is a white solid that is crystalline but often ... It has a slightly salty, alkaline taste resembling that of washing soda (sodium carbonate).
Description : What is the chemical name for ‘Baking Soda’ ? (1) Sodium carbonate (2) Sodium bicarbonate (3) Sodium nitrite (4) Sodium nitrate
Last Answer : Sodium bicarbonate
Description : What is the chemical name for ‘baking soda’? (1) Sodium carbonate (2) Sodium bicarbonate (3) Sodium nitrite (4) Sodium nitrate
Description : An addicting drug which produces little or no physical dependence is: A. Diazepam B. Phenobarbitone C. Amphetamine D. Methadone
Last Answer : C. Amphetamine
Description : Which of the following is a type B (unpredictable) adverse drug reaction: A. Side effect B. Toxic effect C. Idiosyncrasy D. Physical dependence
Last Answer : A. Side effect
Description : Adaptive neurophysiological changes produced by repeated administration of a drug, which result in the appearance of characteristic withdrawal syndrome on discontinuation of the drug is called: A. Drug addiction B. Drug abuse C. Psychological dependence D. Physical dependence
Last Answer : D. Physical dependence
Description : The essential feature in drug addiction is: A. Physical dependence B. Psychological dependence C. Both physical and psychological dependence D. Psychiatric abnormality
Last Answer : B. Psychological dependence
Last Answer : C. Idiosyncrasy
Description : Microsomal enzyme induction can be a cause of: A. Tolerance B. Physical dependence C. Psychological dependence D. Idiosyncrasy
Last Answer : A. Tolerance
Description : In congestive heart failure patients: A. Volume of distribution of all drugs is increased B. Hepatic clearance of drugs is unaffected C. Orally administered diuretics may not be effective, but the same may work parenterally D. Inotropic action of digoxin is attenuated
Last Answer : C. Orally administered diuretics may not be effective, but the same may work parenterally
Description : Study of drug-receptor interaction has now shown that: A. Maximal response occurs only when all receptors are occupied by the drug B. Drugs exert an all or none' action on a ... lock and key' structural features D. Properties of affinity' and intrinsic activity' are independently variable
Last Answer : D. Properties of ‘affinity’ and ‘intrinsic activity’ are independently variable
Description : A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution
Last Answer : D. Redistribution
Description : Which of the following drugs is administered by intranasal spray/application for systemic action: A. Phenylephrine B. Desmopressin C. Azelastine D. Beclomethasone dipropionate
Last Answer : B. Desmopressin
Description : Agonistic action on which of the following adrenergic receptors located on ciliary epithelial cells reduces aqueous secretion: A. β1 receptor B. β2 receptor C. α1 receptor D. α2 receptor
Last Answer : D. α2 receptor
Description : Beta adrenergic blockers lower intraocular tension by: A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors B. Constricting ciliary blood vessels ... action on trabecular meshwork D. Reducing aqueous formation unrelated to beta adrenoceptor mediation
Last Answer : A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors
Description : The site of action of miotics for therapeutic effect in angle closure glaucoma is: A. Canal of Schlemm B. Ciliary body C. Ciliary muscle D. Sphincter pupillae muscle
Last Answer : D. Sphincter pupillae muscle
Description : Edrophonium is more suitable for differentiating myasthenic crisis from cholinergic crisis because of its: A. Shorter duration of action B. Longer duration of action C. Direct action on muscle end-plate D. Selective inhibition of true cholinesterase
Last Answer : A. Shorter duration of action
Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors
Last Answer : B. It is longer acting
Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier
Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate