Which of the following drug can result in result in cyanide poisoning?
A. Amyl nitrite
B. Hydroxycobalamine
C. Sodium nitroprusside
D. Sodium thiosulphate
Description : The antidotal effect of sodium nitrite in cyanide poisoning is dependent upon: A. Chemical combination of sodium nitrite with cyanide B. Vasodilatation caused by sodium nitrite C. ... haemoglobin to methaemoglobin by sodium nitrite D. Facilitation of cyanocobalamine formation by sodium nitrite
Last Answer : C. Conversion of haemoglobin to methaemoglobin by sodium nitrite
Description : The antidotal action of sodium nitrite in cyanide poisoning is based on: A. Physical antagonism B. Chemical antagonism C. Physiological antagonism D. Noncompetitive antagonism
Last Answer : B. Chemical antagonism
Description : Which of the following is a vasodilator drug used for hypertension that lacks a direct effect on autonomic receptors but may provoke anginal attacks? (a) Amyl nitrite (b) Hydralazine (c) Isosorbide mononitrate (d) Nifedipine (e) Nimodipine
Last Answer : Ans: B
Description : Which of the following drugs used for the treatment of angina by inhalation has a very rapid onset and a brief duration of effect ? (a) Amyl nitrite (b) Hydralazine (c) Isosorbide mononitrate (d) Nifedipine (e) Nimodipine
Last Answer : Ans: A
Description : Which of the following is approved for the treatment of hemorrhagic stroke ? (a) Amyl nitrite (b) Hydralazine (c) Isosorbide moninitrate (d) Nifedipine (e) Nimodipine
Last Answer : Ans: E
Description : The agent given sublingually in an acute attack of angina pectoris is (a) Glyceryl trinitrate (b) Amyl nitrite (c) Erythrital tetranitrate (d) Pentaerythritol tetranitrate
Description : Which of the following statements best describes a lead compound? a) A compound that contains the element lead b) A compound from the research laboratory that is chosen to go forward for preclinical and ... of a drug. d) The first compound of a structural class of compounds to reach the market.
Last Answer : c) A molecule that shows some activity or property of interest and serves as the starting point for the development of a drug.
Description : Which of the following patients are at the highest risk of suffering from an adverse drug reaction? a) An 8 month year old infant receiving a prescription for an antibiotic. b) A 22 year old patient ... ACE Inhibitor. d) A 68 year old patient who has oedema receiving a prescription for a diuretic.
Last Answer : d) A 68 year old patient who has oedema receiving a prescription for a diuretic.
Description : Which of the following adverse drug reactions would you report to the Medicines and Healthcare Products regulatory Agency (MHRA) via the yellow card system for reporting? a) A patient ... started taking ramipril. d) A patient complains they have experienced diarrhoea since taking azilsartan.
Last Answer : d) A patient complains they have experienced diarrhoea since taking azilsartan.
Description : Pharmacovigilance is done for monitoring of a) Drug price b) Unethical practises c) Drug safety d) Pharmacy students
Last Answer : c) Drug safety
Description : Patient counselling helps to a) Know chemical structure of drug b) Develop business relations with pharmacist c) Motivate the patient to take medicine for improvement of his/her health status. d) Pass time at old age
Last Answer : c) Motivate the patient to take medicine for improvement of his/her health status.
Description : Which of the following drug is not needed to be TDM? a) Carbamazepine. b) Penicillin. c) Digoxin. d) Gentamicin.
Last Answer : b) Penicillin.
Description : A 75-year-old man had been receiving gentamicin (an aminoglycoside antibiotic) to treat an urinary tract infection. After three months of therapy patient's serum creatinine levels were 10 mg/ ... Type II allergic reaction b)Type III allergic reaction c) Pseudo allergic reaction d) Overdose toxicity
Last Answer : d) Overdose toxicity
Description : Which of the following terms does not describe an Adverse Drug Reaction? a) Idiosyncrasy b) Anaphylaxis c) Teratogenic effect d) Placebo effect
Last Answer : d) Placebo effect
Description : The purpose of preclinical testing is: a. To verify that a drug is sufficiently safe and effective to be tested in humans. b. To undergo preliminary testing in healthy humans to monitor the ... for the larger scale future tests on a widespread population. d. To develop method of drug analysis
Last Answer : a. To verify that a drug is sufficiently safe and effective to be tested in humans.
Description : Case control studies is called as A. Drug-oriented systems. B. Dose-oriented systems. C. Disease-oriented systems. D. Complication-oriented systems.
Last Answer : B. Dose-oriented systems.
Description : Which of the following drug is implicated in the causation of osteomalacia of the bone? A. Steroid B. Estrogen C. Heparin D. Phenytoin
Last Answer : D. Phenytoin
Description : The highest serum drug concentration following a single dose or at a steady state within a dosing interval is called ………. A. Lead B. Peak C. Poison D. Mechanisms
Last Answer : B. Peak
Description : _________ drug is avoided in children’s under 4 years with diarrhea. a) bisacodyl b) loperamide c) Bismuth subsalicylate d) Ciprofloxacin
Last Answer : d) Ciprofloxacin
Description : ___________ drug is usually avoided with breastfeeding. a) Ibuprofen b) propranalol c) Methotrexate d) Naproxe
Last Answer : c) Methotrexate
Description : ___________ antidiabetic drug is preferred for elderly patient a) Gliclazide b) Glibencamide c) Metformin d) Pioglitazone
Last Answer : a) Gliclazide
Description : ___________ is an example of latent adverse drug reactions. a) Antibiotic-associated diarrhea b) Tardive dyskinesia c) Serum sickness d) Severe bronchoconstriction
Last Answer : D
Description : Which of the following drug does not require therapeutic drug monitoring? a) Digitoxin. b) Gentamycin. c) Phenytoin. d) Paracetamol
Last Answer : d) Paracetamol
Description : ________________ causes pharmacodynamic drug interaction. a) Gastric motility changes. b) Stimulation of metabolism. c) Alteration of pH of GIT. d)Interactions at receptor site.
Last Answer : d)Interactions at receptor site.
Description : Which one of these is a genetically determined adverse drug reactions? a) Addication. b) Teratogenecity. c) Carcinogenicity. d) Idiosyncracy.
Last Answer : b) Teratogenecity.
Description : Which of the following reaction is called Augmented adverse drug reactions? a) Genetically determined effects. b) Idiosyncracy. c) Rebound effect on discontinuation d) Allergic reactions & anaphylaxis.
Last Answer : c) Rebound effect on discontinuation
Description : The most specific & sensitive method for assessment of compliance can be used to detect potent therapeutic agent in body fluids is a) Drug analysis. b) Interrogation. c) Urine marker. d) Residual Tablet counting.
Last Answer : a) Drug analysis.
Description : Which of the following responsibility of community pharmacist is in dispensing area? a) Reviews all doses missed, reschedule the doses as necessary & signs all drugs not given notices. b ... of each patient's drug administration forms periodically to ensure all doses have been administered.
Last Answer : b) Supervision of drug administration.
Description : Which of the following responsibility of the clinical pharmacist is in direct patient care area? a) Supervision of drug administration techniques. b) Providing drug information to physicians and ... of each patient's drug administration forms periodically to ensure all doses have been administered.
Last Answer : d) Reviewing of each patient’s drug administration forms periodically to ensure all doses have been administered.
Description : ___________ drug can cause lactic acidosis. a) Metformin b) Pioglitazone c) Repaglinide d) Glibenclamide
Last Answer : a) Metformin
Description : Select the drug which is a potassium channel opener as well as nitric oxide donor: A. Diazoxide B. Sodium nitroprusside C. Minoxidil D. Nicorandil
Last Answer : D. Nicorandil
Description : You are asked to compare the cost of four different antibacterial medicines. Which of the following treatment courses is the lowest cost? a) Medicine A costs £17.00 for 28 tablets. The adult dose is one ... 14 tablets. The adult dose is one tablet each day and the usual treatment duration is 5 days.
Last Answer : c) Medicine C costs £20.00 for 25 tablets. The adult dose is one tablet twice a day and the usual treatment duration is 5 days.
Description : GCP are seen in all of the following except a) Phase I trial b) Phase II trial c) Preclinical trials d) Phase IV trial
Last Answer : c) Preclinical trials
Description : Which of the following is Type B ADRS? a) Hypoglycaemia caused by Insulin b) Dryness of mouth caused by Atropine c) Anaemia in patient with G6PD deficiency caused by Primaquine d) Hyperglycaemia caused by thiazide diuretics
Last Answer : c) Anaemia in patient with G6PD deficiency caused by Primaquine
Description : Which of the following would you classify as a pharmacodynamics interaction? a) ACE inhibitors with potassium-sparing diuretics cause life-threatening hyperkalaemia b) Antacids reduce the absorption ... Increased bleeding due to cimetidine and warfarin d) Probenecid increases half-life of penicillin
Last Answer : a) ACE inhibitors with potassium-sparing diuretics cause life-threatening hyperkalaemia
Description : When tetracycline is given with antacids the absorption of tetracycline ----------------. a) Increases b) Decreases c) Minimally altered d) Not altered at all
Last Answer : b) Decreases
Description : Absorption of Griseofulvin increases with --------------diet. a) Carbohydrate b) Fatty c) protein d) vitamin
Last Answer : b) Fatty
Description : Gary baby syndrome occur in new born with a) Tetracycline b) Chloramphenicol c) Penicillin d) Erythromycin
Last Answer : b) Chloramphenicol
Description : Idiosyncrasy is_______________. a) Type A ADRs b) Type B ADRs c) Type C ADRs d) Type D ADRs
Last Answer : b) Type B ADRs
Description : Which of the following is a technique pharmacists can use to humanize themselves to their patients? a) Using the patient's preferred name in conversation b) Delegating as many tasks as possible to an ... the text of a medication bottle verbatim to a patient d) Providing business cards at the desk
Last Answer : c) Reading the text of a medication bottle verbatim to a patient
Description : GCP provides public assurance that a) Rights and safety of participants are protected b) The rights, safety and wellbeing of research participants are protected and that research data are reliable. c) Results are reliable d) Safety of participant is observed and results are reliable
Last Answer : b) The rights, safety and wellbeing of research participants are protected and that research data are reliable.
Description : Which is person responsible for the conduct of the clinical trial at a trial site? a) Clinical Research Coordinator b) Monitor c) Investigator d) Sponsor
Last Answer : c) Investigator
Description : What are Good Clinical Practices? a. Regulations set in place by Government that how clinical trials are supposed to be managed. b. Clinical practices that adhere to the best standards of ... practice during clinical trials d. The FDA's requirements for how trials are conducted and documented
Last Answer : d. The FDA’s requirements for how trials are conducted and documented
Description : Cimetidine interacts with more drugs than ranitidine because; a) It is subjected to greater first pass metabolism b) It is a more potent enzyme inducer c) It is a more potent enzyme inhibitor d) It has better oral absorption
Last Answer : c) It is a more potent enzyme inhibitor
Description : ______________ of clinical trial involves first time human trial in a small number of patients. a Phase I b Phase II c Phase III d Phase IV
Last Answer : a Phase I
Description : A 92-year-old woman is an inpatient in the geriatric unit. She has multivascular dementia. She is more confused and agitated. She has been given lorazepam 4 mg intramuscularly. She is now unconscious ... A. Activated charcoal B. Flumazenil C. N-acetyl cysteine D. Naloxone E. Protamine sulphate
Last Answer : B. Flumazenil
Description : Which of the following medication is safe to use in the third trimester of pregnancy? A. Acetaminophen B. Warfarin C. Aspirin D. Oxycodone
Last Answer : A. Acetaminophen
Description : Which of the following antihypertensive agents should be avoided in the elderly patients? A. Amlodipine B. Atenolol C. Benazepril D. Methyldopa
Last Answer : D. Methyldopa
Description : Which of the following is a valid therapeutic use of interaction? A. Use of Probenecid with Penicillin B. Giving Aspirin with warfarin C. Instructing patient to take levofloxacin with milk or antacid D. Treatment of depression of MAO Inhibitor and Citalopram
Last Answer : A. Use of Probenecid with Penicillin