Description : The bladder trigone and prostatic muscles are relaxed by: A. Adrenergic α1 agonists B. Adrenergic α1 antagonists C. Adrenergic α2 agonists D. Adrenergic α2 antagonists
Last Answer : B. Adrenergic α1 antagonists
Description : Which of the following is not the basis for subclassifying β adrenergic receptors into β1 and β2 : A. Selectivity of agonists B. Selectivity of antagonists C. Transducer pathway of response effectuation D. Organ selective location
Last Answer : C. Transducer pathway of response effectuation
Description : Which of the following is not the basis for subclassifying β adrenergic receptors into β 1 and β 2: A. Selectivity of agonists B. Selectivity of antagonists C. Transducer pathway of response effectuation D. Organ selective location
Description : Currently, the first choice drug for open angle glaucoma is: A. Miotic eye drops B. Ocular α2 adrenergic agonists C. Ocular prostaglandin analogues D. Ocular β adrenergic blockers
Last Answer : D. Ocular β adrenergic blockers
Description : The smooth muscle structure that is relaxed by cholinergic drugs is: A. Colon B. Gastric fundus C. Major bronchi D. Bladder trigone
Last Answer : D. Bladder trigone
Description : Phosphoinositide cascade is activated on binding of catecholamines to (A) α1-Adrenergic receptors (B) α2-Adrenergic receptors (C) β1-Adrenergic receptors (D) β2-Adrenergic receptors
Last Answer : Answer : A
Description : Astimulatory G-protein transduces the signals from (A) α1-and β1-adrenergic receptors (B) α2-and β2-adrenergic receptors (C) α1-and α2-adrenergic receptors (D) β1-and β2-adrenergic receptors
Last Answer : Answer : D
Description : The primary reason for preferring phentolamine as the α adrenergic blocker for performing diagnostic test for pheochromocytoma is: A. It produces rapid and short lasting α-adrenergic blockade B. It equally ... It is the most potent α blocker D. It has no additional β adrenergic blocking property
Last Answer : A. It produces rapid and short lasting α-adrenergic blockade
Description : Agonistic action on which of the following adrenergic receptors located on ciliary epithelial cells reduces aqueous secretion: A. β1 receptor B. β2 receptor C. α1 receptor D. α2 receptor
Last Answer : D. α2 receptor
Description : The following statement is not true of log dose-response curve: A. It is almost linear except at the ends B. It is a rectangular hyperbola C. It facilitates comparison of different agonists D. It can help in discriminating between competitive and noncompetitive antagonists
Last Answer : B. It is a rectangular hyperbola
Description : Down regulation of receptors can occur as a consequence of: A. Continuous use of agonists B. Continuous use of antagonists C. Chronic use of CNS depressants D. Denervation
Last Answer : A. Continuous use of agonists
Description : Receptors perform the following function/functions: A. Ligand recognition B. Signal transduction C. Both ligand recognition and signal transduction D. Disposal of agonists and antagonists
Last Answer : C. Both ligand recognition and signal transduction
Description : Leukotriene antagonists are used in bronchial asthma: A. For terminating acute attacks B. As monotherapy in place of β2 agonists C. As adjuvants to β2 agonists for avoiding corticosteroids D. As nebulized powder in refractory cases
Last Answer : C. As adjuvants to β2 agonists for avoiding corticosteroids
Description : Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy
Last Answer : C. It does not concurrently enhance noradrenaline release
Description : Low dose therapy with the following category of antihypertensive drugs has been found to be more advantageous in the long-term than high dose therapy with the same drugs: A. β adrenergic blockers B. α1 adrenergic blockers C. Central sympatholytics D. Diuretics
Last Answer : D. Diuretics
Description : Rapid intravenous injection of clonidine causes rise in BP due to: A. Stimulation of vasomotor centre B. Release of noradrenaline from adrenergic nerve endings C. Agonistic action on vascular α2 adrenergic receptors D. Cardiac stimulation
Last Answer : C. Agonistic action on vascular α2 adrenergic receptors
Description : The following is a skeletal muscle relaxant that acts as a central α2 adrenergic agonist: A. Tizanidine B. Brimonidine C. Chlormezanone D. Quinine
Last Answer : A. Tizanidine
Description : Insulin release from pancreatic β cells is augmented by the following except: A. Ketone bodies B. Glucagon C. Vagal stimulation D. Alfa adrenergic agonists
Last Answer : D. Alfa adrenergic agonist
Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve
Last Answer : C. Do not block any effect of injected adrenaline
Description : Adrenergic β2 agonists produce muscle tremor by: A. Facilitating neuromuscular transmission B. Incomplete fusion of contractile response of individual fibres C. Enhanced firing of muscle spindles D. Both (b) and (c) are correct
Last Answer : D. Both (b) and (c) are correct
Description : The α2 adrenoceptors are: A. Located exclusively on the adrenergic nerve endings B. Prejunctional, postjunctional as well as extrajunctional in location C. Selectively activated by phenylephrine D. Selectively blocked by clonidine
Last Answer : B. Prejunctional, postjunctional as well as extrajunctional in location
Description : The following is an α2 adrenergic agonist used as eyedrops to lower intraocular pressure: A. Brinzolamide B. Bambuterol C. Brimonidine D. Latanoprost
Last Answer : C. Brimonidine
Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve stimulation
Description : A specific cortisol binding protein, transcortin is a (A) Albumin (B) α1-Globulin (C) α2-Globulin (D) β-Globulin
Last Answer : Answer : C
Description : In the blood the vitamin esters are attached to (A) α1-lipoproteins (B) α2-lipoproteins (C) β-lipoproteins (D) γ-lipoproteins
Description : Retinol is transported to the blood as retinol attached to (A) α1-globulin (B) α2-globulin (C) β-globulin (D) γ-globulin
Description : In Thymol turbidity test the protein involved is mainly (A) Albumin (B) α1-Globulin (C) α2-Globulin (D) β Globulin
Description : Ceruloplasmin is (A) α1-globulin (B) α2-globulin (C) β-globulin (D) None of these
Description : The following sympathomimetic amine has agonistic action on α1 + α2 + β1 + β3 adrenoceptors, but not on β2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine
Last Answer : B. Noradrenaline
Description : Prazosin is an effective antihypertensive while nonselective a adrenergic blockers are not because (a) It is the only orally active a blocker (b) It improves plasma lipid profile (c) It does not concurrently enhance noradrenaline release (d) It improves urine flow in males with prostatic hypertrophy
Last Answer : Ans: C
Description : Select the β-adrenergic blocker that has additional α1 blocking, vasodilator and antioxidant properties: A. Carvedilol B. Celiprolol C. Acebutolol D. Metoprolol
Last Answer : A. Carvedilol
Description : Continuous exposure of ctecholaminesensitive cells and tissues to adrenergic agonists causes a progressive diminition in their capacity to respond, this phenomenon is called as (a) Refractoriness (b) Desensitization (c) Tachyphylaxis (d) All of the above
Last Answer : Ans: D
Description : Choose the correct statement from the following about a1 – adrenergic receptor agonists (a) Norepinephrine > isoproterenol > epinephrine (b) Norepinephrine < epinephrine > isoproterenol (c) Epinephrine = norepinephrine >> isoproterenol (d) Epinephrine > isoproterenol > norepinephrine
Description : Select the correct statement from the following about a1 – adrenergic receptor agonists (a) Isoproterenol > epinephrine = norepinephrine (b) Epinephrine > isoproterenol > norepinephrine (c) Isoproterenol = epinephrine = norepinephrine (d) Epinephrine = norepinephrine > isoproterenol
Last Answer : Ans: A
Description : In comparison to inhaled β 2 adrenergic agonists, the inhaled anticholinergics: A. Are more effective in bronchial asthma B. Are better suited for control of an acute attack of asthma C. Produce slower response in bronchial asthma D. Produce little benefit in chronic obstructive lung disease
Last Answer : C. Produce slower response in bronchial asthma
Description : The obstructive and irritative symptom complex caused by benign prostatic hypertrophy is termed a) prostatism. Symptoms of prostatism include increased frequency of urination, nocturia, urgency, dribbling, ... . d) prostatectomy. Prostatectomy refers to the surgical removal of the prostate gland.
Last Answer : a) prostatism. Symptoms of prostatism include increased frequency of urination, nocturia, urgency, dribbling, and a sensation that the bladder has not completely emptied.
Description : The following drug has been found to improve urine flow in elderly males with benign prostatic hypertrophy: A. Nifedipine B. Prazosin C. Disopyramide D. Imipramine
Last Answer : B. Prazosin
Description : he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to ... release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori
Last Answer : B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect
Description : In patients with benign prostatic hypertrophy, finasteride exerts the following action/actions: A. Reduces size of the prostate gland B. Increases peak urinary flow rate C. Relaxes vesical sphincter D. Both 'A' and 'B' are correct
Last Answer : D. Both 'A' and 'B' are correct
Description : Finasteride acts by: A. Blocking testosterone receptors in the prostate gland B. Reducing testosterone secretion from testes C. Reducing LH secretion from pituitary D. Lowering circulating as well as prostatic dihydrotestosterone concentration
Last Answer : D. Lowering circulating as well as prostatic dihydrotestosterone concentration
Description : Which of the following is a steroid 5α-reductase inhibitor that has been found useful in benign prostatic hypertrophy and male pattern baldness: A. Flutamide B. Finasteride C. Prazosin D. Minoxidil
Last Answer : B. Finasteride