Select the ergot compound which is primarily used for dementia: A. Bromocriptine B. Ergotamine C. Codergocrine D. Methysergide

Select the ergot compound which is primarily used for dementia: A. Bromocriptine B. Ergotamine C. Codergocrine D. Methysergide
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C. Codergocrine
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Choose the ergot alkaloid that is well absorbed orally, has weak vascular but prominent uterine stimulant action: A. Ergometrine B. Ergotamine C. Dihydroergotamine D. Dihydroergotoxine

Description : Choose the ergot alkaloid that is well absorbed orally, has weak vascular but prominent uterine stimulant action: A. Ergometrine B. Ergotamine C. Dihydroergotamine D. Dihydroergotoxine

Last Answer : A. Ergometrine

The following drug claimed to have a therapeutic effect in senile dementia has α adrenergic blocking activity: A. Piracetam B. Pyritinol C. Codergocrine D. Methylphenidate

Description : The following drug claimed to have a therapeutic effect in senile dementia has α adrenergic blocking activity: A. Piracetam B. Pyritinol C. Codergocrine D. Methylphenidate

Last Answer : C. Codergocrine

Which of the following drugs is most commonly used for prophylaxis of migraine: A. Ergotamine B. Propranolol C. Methysergide D. Sumatriptan

Description : Which of the following drugs is most commonly used for prophylaxis of migraine: A. Ergotamine B. Propranolol C. Methysergide D. Sumatriptan

Last Answer : B. Propranolol

Select the correct statement in relation to drug therapy of migraine: A. Simple analgesics like paracetamol are ineffective in migraine B. Ergot alkaloids are used for prophylaxis as well as treatment of migraine attacks C. Use of ergot alkaloids is restricted to severe or resistant cases D. Ergot alkaloids should be given till 24 hours after an attack has subsided

Description : Select the correct statement in relation to drug therapy of migraine: A. Simple analgesics like paracetamol are ineffective in migraine B. Ergot alkaloids are used for prophylaxis as well as treatment ... resistant cases D. Ergot alkaloids should be given till 24 hours after an attack has subsided

Last Answer : C. Use of ergot alkaloids is restricted to severe or resistant cases

Which of the following is most useful in the treatment of hyperprolactinemia ? (a) Bromocriptine (b) Cimetidine (c) Ergotamine (d) Ketanserin (e) LSD

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Methysergide has lost popularity as a prophylactic drug for migraine because of its: A. Poor efficacy B. Potential to cause visceral fibrosis C. Oxytocic action D. Potential to aggravate ischaemic heart disease

Description : Methysergide has lost popularity as a prophylactic drug for migraine because of its: A. Poor efficacy B. Potential to cause visceral fibrosis C. Oxytocic action D. Potential to aggravate ischaemic heart disease

Last Answer : B. Potential to cause visceral fibrosis

Select the drug that improves some symptoms in Alzheimer’s dementia by increasing brain acetylcholine levels: A. Pemoline B. Donepezil C. Nicergoline D. Piribedi

Description : Select the drug that improves some symptoms in Alzheimer’s dementia by increasing brain acetylcholine levels: A. Pemoline B. Donepezil C. Nicergoline D. Piribedi

Last Answer : B. Donepezi

Ergotamine relieves migraine by: A. Blocking vascular α adrenergic receptors B. Blocking vascular 5-HT2 receptors C. Dilating cranial arterio-venous shunt channels D. Constricting cranial vessels and reducing perivascular neurogenic inflammation

Description : Ergotamine relieves migraine by: A. Blocking vascular α adrenergic receptors B. Blocking vascular 5-HT2 receptors C. Dilating cranial arterio-venous shunt channels D. Constricting cranial vessels and reducing perivascular neurogenic inflammation

Last Answer : D. Constricting cranial vessels and reducing perivascular neurogenic inflammation

The nonsteroidal antiinflammatory drugs are more effective in migraine: A. Without aura B. With aura C. Than ergotamine D. When combined with propranolol

Description : The nonsteroidal antiinflammatory drugs are more effective in migraine: A. Without aura B. With aura C. Than ergotamine D. When combined with propranolol

Last Answer : A. Without aura

The drug which produces vasoconstriction despite being an α adrenergic blocker is: A. Phenoxybenzamine B. Ergotamine C. Dihydroergotoxine D. Tolazoline

Description : The drug which produces vasoconstriction despite being an α adrenergic blocker is: A. Phenoxybenzamine B. Ergotamine C. Dihydroergotoxine D. Tolazoline

Last Answer : B. Ergotamine

The most dependable emetic used to expel ingested poisons is: A. Intramuscular emetine B. Oral syrup ipecacuanha C. Intramuscular apomorphine D. Oral bromocriptine

Description : The most dependable emetic used to expel ingested poisons is: A. Intramuscular emetine B. Oral syrup ipecacuanha C. Intramuscular apomorphine D. Oral bromocriptine

Last Answer : C. Intramuscular apomorphine

Gynaecomastia can occur as a side effect of: A. Bromocriptine B. Cimetidine C. Famotidine D. Levodopa

Description : Gynaecomastia can occur as a side effect of: A. Bromocriptine B. Cimetidine C. Famotidine D. Levodopa

Last Answer : B. Cimetidine

For majority of patients of parkinsonism the standard drug therapy is: A. Levodopa B. Levodopa + carbidopa C. Levodopa + trihexiphenidyl D. Bromocriptine

Description : For majority of patients of parkinsonism the standard drug therapy is: A. Levodopa B. Levodopa + carbidopa C. Levodopa + trihexiphenidyl D. Bromocriptine

Last Answer : B. Levodopa + carbidopa

The following drug is effective in chlorpromazine induced parkinsonism: A. Trihexyphenidyl B. Selegiline C. Bromocriptine D. Levodopa + carbidopa

Description : The following drug is effective in chlorpromazine induced parkinsonism: A. Trihexyphenidyl B. Selegiline C. Bromocriptine D. Levodopa + carbidopa

Last Answer : A. Trihexyphenidyl

Tolerance to the antiparkinsonian action develops most rapidly in the case of: A. Levodopa B. Levodopa + carbidopa C. Amantadine D. Bromocriptine

Description : Tolerance to the antiparkinsonian action develops most rapidly in the case of: A. Levodopa B. Levodopa + carbidopa C. Amantadine D. Bromocriptine

Last Answer : C. Amantadine

The antiparkinsonian drug which acts by inhibiting the degradation of dopamine in the brain is: A. Carbidopa B. Amantadine C. Selegiline D. Bromocriptine

Description : The antiparkinsonian drug which acts by inhibiting the degradation of dopamine in the brain is: A. Carbidopa B. Amantadine C. Selegiline D. Bromocriptine

Last Answer : C. Selegiline

The following drug combination should not be used in parkinsonism: A. Levodopa + anticholinergics B. Levodopa + amantadine C. Bromocriptine + levodopa D. Amantadine + anticholinergics

Description : The following drug combination should not be used in parkinsonism: A. Levodopa + anticholinergics B. Levodopa + amantadine C. Bromocriptine + levodopa D. Amantadine + anticholinergics

Last Answer : D. Amantadine + anticholinergics

Ropinirole differs from bromocriptine in the following respect: A. It does not directly activate dopamine D2 receptors B. It produces milder gastrointestinal side effects C. In early cases of parkinsonism, it is less likely to need levodopa supplementation D. Both 'B' and 'C' are correct

Description : Ropinirole differs from bromocriptine in the following respect: A. It does not directly activate dopamine D2 receptors B. It produces milder gastrointestinal side effects C. In early cases of parkinsonism, it is less likely to need levodopa supplementation D. Both 'B' and 'C' are correct

Last Answer : D. Both 'B' and 'C' are correct

In the treatment of parkinsonism, bromocriptine differs from levodopa in the following respects except: A. It does not need conversion to an active metabolite B. It has a longer duration of action C. It activates dopamine D2 receptors, with little/antagonistic action on D1 receptors D. It does not produce behavioral/psychiatric side effect

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Last Answer : D. It does not produce behavioral/psychiatric side effects

Though bromocriptine acts directly on dopamine receptors, it is used in parkinsonism only as a supplement to levodopa because: A. It has low efficacy B. It produces marked dyskinesias C. Used alone, its effective doses produce intolerable side effects D. Its therapeutic effect takes long time to develop

Description : Though bromocriptine acts directly on dopamine receptors, it is used in parkinsonism only as a supplement to levodopa because: A. It has low efficacy B. It produces marked dyskinesias C. ... its effective doses produce intolerable side effects D. Its therapeutic effect takes long time to develop

Last Answer : C. Used alone, its effective doses produce intolerable side effect

The dopamine D2 receptor has the following feature: A. It is excitatory in nature B. It is negatively coupled to adenyl cyclase C. It is selectively blocked by bromocriptine D. It is not blocked by metoclopramide

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Last Answer : B. It is negatively coupled to adenyl cyclase

The most effective drug in parkinsonism is: A. Bromocriptine B. Selegiline C. Levodopa + carbidopa D. Biperiden

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Last Answer : C. Bromocriptine

6.12 The most prominent action of bromocriptine is: A. Dopamine D2 agonism B. Dopamine D2 antagonism C. Dopamine D1 antagonism D. α adrenergic antagonism

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Last Answer : A. Dopamine D2 agonism

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Last Answer : B. Vomiting

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Last Answer : A. Pentazocine

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Last Answer : C. It is primarily used as a carrier and adjuvant to other anaesthetics

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Description : Select the compound that is preferred for high dose intravenous corticosteroid pulse therapy: A. Cortisone B. Hydrocortisone C. Triamcinolone D. Methyl prednisolone

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The ‘amine’ ergot alkaloid differs from ‘amino acid’ ergot alkaloid in that it has: A. High oral bioavailability B. Better CNS penetrability C. Weaker oxytocic action D. Strong anti-5-HT action

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Last Answer : A. High oral bioavailability

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Last Answer : C. It is excreted unchanged, mainly by glomerular filtration

Aminoglycoside antibiotics have the following property common to all members: A. They are primarily active against aerobic gram negative bacilli B. They are more active in acidic medium C. They readily enter cells and are distributed in total body water D. They are nearly completely metabolized in liver

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Last Answer : A. They are more likely to produce crystalluria in alkaline urine in which they are less soluble

2 Which antibiotic is primarily bacteriostatic but becomes bactericidal at higher concentrations: A. Erythromycin B. Tetracycline C. Chloramphenicol D. Ampicillin

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Activation of the following type of receptors present on myenteric neurones by metoclopramide is primarily responsible for enhanced acetylcholine release improving gastric motility: A. Muscarinic M1 B. Serotonergic 5-HT3 C. Serotonergic 5-HT4 D. Dopaminergic D2

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Last Answer : C. Serotonergic 5-HT4

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Last Answer : A. Prompt pain relief

The side effect which primarily limits acceptability of oral iron therapy is: A. Epigastric pain and bowel upset B. Black stools C. Staining of teeth D. Metallic taste

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Last Answer : A. Epigastric pain and bowel upset