Select the compound which used for hormone replacement therapy in postmenopausal women serves the purpose of both estrogen and progestin with weak androgenic activity: A. Tibolone B. Mestranol C. Desogestrel D. Gestodene

Select the compound which used for hormone replacement therapy in postmenopausal women serves
the purpose of both estrogen and progestin with
weak androgenic activity:
A. Tibolone
B. Mestranol
C. Desogestrel
D. Gestodene
by

1 Answer

Answer :

A. Tibolone
by

Related questions

Select the correct statement about tibolone: A. It is an antiestrogen used for palliative treatment of carcinoma breast B. It is an estrogenic + progestational steroid used for hormone replacement therapy in postmenopausal women C. It is an antiandrogen used for male pattern baldness D. It is a nonsteroidal estrogen used topically for senile vaginitis

Description : Select the correct statement about tibolone: A. It is an antiestrogen used for palliative treatment of carcinoma breast B. It is an estrogenic + progestational steroid used for hormone replacement ... for male pattern baldness D. It is a nonsteroidal estrogen used topically for senile vaginitis

Last Answer : B. It is an estrogenic + progestational steroid used for hormone replacement therapy in postmenopausal women

Select the progestin preparation for coadministration with estrogen for hormone replacement therapy that does not counteract the beneficial effect of the latter on lipid profile due to lack of androgenic activity: A. Micronized oral progesterone B. Norethindrone C. Lynestrenol D. Medroxyprogesterone acetate (p. 281-282)

Description : Select the progestin preparation for coadministration with estrogen for hormone replacement therapy that does not counteract the beneficial effect of the latter on lipid profile due to lack of ... oral progesterone B. Norethindrone C. Lynestrenol D. Medroxyprogesterone acetate (p. 281-282)

Last Answer : Select the indication for which a progestin is used alone without combining with an estrogen: A. Threatened abortion B. Dysfunctional uterine bleeding C. Hormone replacement therapy D. Premenstrual tension

The distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile

Description : The distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile

Last Answer : C. It has additional androgenic acitivity

he distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile

Description : he distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile

Last Answer : C. It has additional androgenic acitivity

The daily dose of estrogen for hormone replacement therapy in postmenopausal women is: A. Same as for contraception B. Higher than that for contraception C. Lower than that for contraception D. Variable depending on the age of the woman

Description : The daily dose of estrogen for hormone replacement therapy in postmenopausal women is: A. Same as for contraception B. Higher than that for contraception C. Lower than that for contraception D. Variable depending on the age of the woman

Last Answer : C. Lower than that for contraception

Estrogen replacement therapy for postmenopausal women is contraindicated in subjects with: A. Leg vein thrombosis B. Undiagnosed vaginal bleeding C. Migraine D. All of the above

Description : Estrogen replacement therapy for postmenopausal women is contraindicated in subjects with: A. Leg vein thrombosis B. Undiagnosed vaginal bleeding C. Migraine D. All of the above

Last Answer : D. All of the above

Estrogen therapy in postmenopausal women has been implicated in increasing the risk of the following disorders except: A. Gall stones B. Osteoporosis C. Endometrial carcinoma D. Breast cancer

Description : Estrogen therapy in postmenopausal women has been implicated in increasing the risk of the following disorders except: A. Gall stones B. Osteoporosis C. Endometrial carcinoma D. Breast cancer

Last Answer : B. Osteoporosis

Addition of a progestin for 10-12 days each month to estrogen replacement therapy in menopausal women is recommended because the progestin: A. Blocks the increased risk of myocardial infarction due to estrogen B. Blocks the increased risk of endometrial carcinoma due to estrogen C. Reverses vulval atrophy occurring in postmenopausal women D. Enhances the metabolic benefits of estrogen treatment

Description : Addition of a progestin for 10-12 days each month to estrogen replacement therapy in menopausal women is recommended because the progestin: A. Blocks the increased risk of myocardial ... vulval atrophy occurring in postmenopausal women D. Enhances the metabolic benefits of estrogen treatment

Last Answer : The estrogen commonly used for hormone replacement therapy in menopausal women is: A. Ethinylestradiol B. Estradiol benzoate C. Diethylstilbestrol D. Conjugated estrogens

What is true of tamoxifen: A. It can induce endometrial proliferation in postmenopausal women B. It exerts antiestrogenic activity in bone C. It raises LDL-cholesterol levels D. It is ineffective in estrogen receptor-negative breast cancer

Description : What is true of tamoxifen: A. It can induce endometrial proliferation in postmenopausal women B. It exerts antiestrogenic activity in bone C. It raises LDL-cholesterol levels D. It is ineffective in estrogen receptor-negative breast cancer

Last Answer : A. It can induce endometrial proliferation in postmenopausal women

Addition of a progestin for 10-12 days every month to cyclic estrogen replacement therapy during menopause is recommended because the progestin: A. Prevents osteoporosis B. Prevents irregular bleeding C. Blocks increased risk of endometrial carcinoma D. Both ‘B’ and ‘C’ are correct

Description : Addition of a progestin for 10-12 days every month to cyclic estrogen replacement therapy during menopause is recommended because the progestin: A. Prevents osteoporosis B. Prevents irregular bleeding C. Blocks increased risk of endometrial carcinoma D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Which of the following is a selective estrogen receptor modulator that improves bone mineral density in postmenopausal women: A. Clomiphene citrate B. Raloxifene C. Ormeloxifene D. Alendronate

Description : Which of the following is a selective estrogen receptor modulator that improves bone mineral density in postmenopausal women: A. Clomiphene citrate B. Raloxifene C. Ormeloxifene D. Alendronate

Last Answer : B. Raloxifene

The purpose/purposes served by the progestin component of the combined estrogen + progestin contraceptive pill is/are: A. Suppression of ovulation B. Prompt bleeding at the end of the course C. Blockade of increased risk of endometrial carcinoma D. All of the above

Description : The purpose/purposes served by the progestin component of the combined estrogen + progestin contraceptive pill is/are: A. Suppression of ovulation B. Prompt bleeding at the end of the course C. Blockade of increased risk of endometrial carcinoma D. All of the above

Last Answer : D. All of the above

Choose the correct statement about anabolic steroids: A. They are testosterone congeners having anabolic but no androgenic activity B. They are androgens with relatively selective anabolic activity C. They are suitable for long-term therapy in children D. Both ‘B’ and ‘C’ are correct

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The estrogen commonly used for hormone replacement therapy in menopausal women is: A. Ethinylestradiol B. Estradiol benzoate C. Diethylstilbestrol D. Conjugated estrogens

Description : The estrogen commonly used for hormone replacement therapy in menopausal women is: A. Ethinylestradiol B. Estradiol benzoate C. Diethylstilbestrol D. Conjugated estrogens

Last Answer : D. Conjugated estrogen

The currently used injectable hormonal contraceptive contains: A. Long acting progestin B. Long acting estrogen C. Both long acting estrogen and progestin D. Chorionic gonadotropin

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Last Answer : A. Long acting progestin

A progestin and an estrogen are combined in oral contraceptive pill because: A. The estrogen blocks the side effects of the progestin B. The progestin blocks the side effects of the estrogen C. Both synergise to suppress ovulation D. Both synergise to produce hostile cervical mucus

Description : A progestin and an estrogen are combined in oral contraceptive pill because: A. The estrogen blocks the side effects of the progestin B. The progestin blocks the side effects of the estrogen C. Both synergise to suppress ovulation D. Both synergise to produce hostile cervical mucus

Last Answer : C. Both synergise to suppress ovulation

The following contraceptive acts primarily by interfering with implantation of blastocyst: A. Gossypol B. Centchroman C. Combined estrogen-progestin pill D. Phased pill

Description : The following contraceptive acts primarily by interfering with implantation of blastocyst: A. Gossypol B. Centchroman C. Combined estrogen-progestin pill D. Phased pill

Last Answer : B. Centchroman

On stoppage of the combined estrogen-progestin contraceptive pill, fertility returns after: A. 1–2 months B. 4–6 months C. 6–12 months D. Uncertain period

Description : On stoppage of the combined estrogen-progestin contraceptive pill, fertility returns after: A. 1–2 months B. 4–6 months C. 6–12 months D. Uncertain period

Last Answer : A. 1–2 months

The primary mechanism of action of the combined estrogen-progestin oral contraceptive pill is: A. Production of cervical mucus hostile to sperm penetration B. Suppression of FSH and LH release C. Making endometrium unsuitable for implantation D. Enhancing uterine contractions to dislodge the fertilized ovum

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The most popular form of hormonal contraception is: A. Combined estrogen + progestin oral pill B. Phased estrogen + progestin oral pill C. Postcoital estrogen + progestin pill D. Depot progestin injection

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Last Answer : A. Combined estrogen + progestin oral pill

In which of the following conditions estrogen is not the primary drug but is added to progestin as adjuvant: A. Dysfunctional uterine bleeding B. Menopausal syndrome C. Osteoporosis D. Atrophic vaginitis

Description : In which of the following conditions estrogen is not the primary drug but is added to progestin as adjuvant: A. Dysfunctional uterine bleeding B. Menopausal syndrome C. Osteoporosis D. Atrophic vaginitis

Last Answer : A. Dysfunctional uterine bleeding

Mifepristone possesses the following activities: A. Potent antiprogestin + weak androgenic B. Potent antiprogestin + weak antiglucocorticoid C. Potent antiestrogenic + weak antiprogestin D. Potent antiestrogenic + weak glucocorticoid

Description : Mifepristone possesses the following activities: A. Potent antiprogestin + weak androgenic B. Potent antiprogestin + weak antiglucocorticoid C. Potent antiestrogenic + weak antiprogestin D. Potent antiestrogenic + weak glucocorticoid

Last Answer : Mifepristone possesses the following activities: A. Potent antiprogestin + weak androgenic B. Potent antiprogestin + weak antiglucocorticoid C. Potent antiestrogenic + weak antiprogestin D. Potent antiestrogenic + weak glucocorticoid

Side effects of cyclic progestin therapy include the following except: A. Headache B. Gastroesophageal reflux C. Breast dyscomfort D. Irregular bleeding

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Last Answer : D. Irregular bleeding

Addition of pyrazinamide and ethambutol for the first two months to the isoniazid + rifampin therapy of tuberculosis serves the following purpose(s): A. Reduces the total duration of therapy to 6 months B. Produces more rapid sputum conversion C. Permits reduction of rifampin dose D. Both ‘A’ and ‘B’ are correct

Description : Addition of pyrazinamide and ethambutol for the first two months to the isoniazid + rifampin therapy of tuberculosis serves the following purpose(s): A. Reduces the total duration of therapy to 6 months B. ... sputum conversion C. Permits reduction of rifampin dose D. Both A' and B' are correct

Last Answer : D. Both ‘A’ and ‘B’ are correc

The 19-Norprogestins differ from progesterone derivatives in that they: A. Have potent antiovulatory activity B. Have no additional androgenic activity C. Have no additional estrogenic activity D. Are preferred for use in endometriosi

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Does postmenopausal hormone therapy cause continuation of menses?

Description : Does postmenopausal hormone therapy cause continuation of menses?

Last Answer : answer:This is a really complicated question; having a light period is the least of concerns when considering HRT. Check out Webmd: http://www.webmd.com/menopause/features/HRT-revisiting-the-hormone- ... hand fan worked just fine. Also I found thatdancing around in the snow in underwear was cooling,

Tamoxifen citrate is used for palliative treatment of carcinoma breast in: A. Premenopausal women B. Postmenopausal women C. Mastectomized patients D. All of the above

Description : Tamoxifen citrate is used for palliative treatment of carcinoma breast in: A. Premenopausal women B. Postmenopausal women C. Mastectomized patients D. All of the above

Last Answer : D. All of the above

Which of the following statements most closely reflects the current status of estrogens in postmenopausal women: A. Estrogens should be prescribed routinely to all menopausal women B. Estrogens should be prescribed when menopausal symptoms are severe C. Estrogens should be prescribed only when there is radiological evidence of osteoporosis D. Estrogens should be prescribed along with a progestin after considering risk:benefit ratio in individual patients

Description : Which of the following statements most closely reflects the current status of estrogens in postmenopausal women: A. Estrogens should be prescribed routinely to all menopausal women B. ... should be prescribed along with a progestin after considering risk:benefit ratio in individual patients

Last Answer : . Estrogens should be prescribed along with a progestin after considering risk:benefit ratio in individual patients

Urinary 17 ketosteroids (A) Are not found in women (B) Reflect the total production of androgenic substances (C) Indicate the total production of sex hormone (D) Are highly active androgens

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Last Answer : Answer : B

Young women are protected against myocardial infaracation because of the activity of (A) Estrogen (B) Progesterone (C) Growth hormone (D) Oxytocin

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Last Answer : Answer : A

Estrogen therapy can worsen the following associated conditions except: A. Migraine B. Cholelithiasis C. Acne vulgaris D. Endometriosis

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Transdermal estradiol differs from oral estrogen therapy in that it: A. Causes less induction of hepatic synthesis of clotting factors B. Does not inhibit FSH secretion C. Does not affect vaginal cytology D. All of the above are correct

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Select the compound that is preferred for high dose intravenous corticosteroid pulse therapy: A. Cortisone B. Hydrocortisone C. Triamcinolone D. Methyl prednisolone

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Last Answer : D. Methyl prednisolone

Fluconazole differs from ketoconazole in that: A. It is not active by the oral route B. It is a more potent inhibitor of drug metabolism C. It is not effective in cryptococcal meningitis D. It is unlikely to produce anti-androgenic side effects

Description : Fluconazole differs from ketoconazole in that: A. It is not active by the oral route B. It is a more potent inhibitor of drug metabolism C. It is not effective in cryptococcal meningitis D. It is unlikely to produce anti-androgenic side effects

Last Answer : D. It is unlikely to produce anti-androgenic side effects

The progestin used in combined oral contraceptive pill is a 19-nortestosterone derivative because: A. They have potent antiovulatory action of their own B. They do not produce any metabolic effects C. They produce fewer side effects D. They are longer acting

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Last Answer : A. They have potent antiovulatory action of their own

The following antipsychotic drug has weak dopamine D2 but additional 5-HT2 blocking activity and benefits both positive and negative symptoms of schizophrenia: A. Loxapine B. Clozapine C. Pimozide D. Penfluridol

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Last Answer : B. Clozapin

Compared to other antipsychotic drugs, the distinctive feature of penfluridol is: A. Very long duration of action B. Weak dopamine D2 blocking activity C. Lack of extrapyramidal side effects D. Additional 5-HT2 receptor blocking activity

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Last Answer : A. Very long duration of action

The following drug has potent antiandrogenic and weak progestational activity: A. Ethylestrenol B. Clomiphene citrate C. Cyproterone acetate D. Magestrol acetate

Description : The following drug has potent antiandrogenic and weak progestational activity: A. Ethylestrenol B. Clomiphene citrate C. Cyproterone acetate D. Magestrol acetate

Last Answer : D. Magestrol acetate

Injection of adrenaline along with a local anaesthetic serves the following purpose: A. Lowers the concentration of the local anaesthetic to produce nerve block B. Prolongs the duration of local anaesthesia C. Increases the anaesthetised area D. Reduces the local toxicity of the local anaesthetic

Description : Injection of adrenaline along with a local anaesthetic serves the following purpose: A. Lowers the concentration of the local anaesthetic to produce nerve block B. Prolongs the duration of local anaesthesia C. Increases the anaesthetised area D. Reduces the local toxicity of the local anaesthetic

Last Answer : B. Prolongs the duration of local anaesthesia

Chlorpromazine therapy increases the secretion of the following hormone: A. Prolactin B. Gonadotropin C. Corticotropin D. Antidiuretic hormone

Description : Chlorpromazine therapy increases the secretion of the following hormone: A. Prolactin B. Gonadotropin C. Corticotropin D. Antidiuretic hormone

Last Answer : A. Prolactin

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Last Answer : (b) Posterior Vasopressin Stimulates pituitary reabsorption of water in the distal tubules in the nephron

Select the option which correctly matches the endocrine gland with its hormone and its function. Endocrine Hormone Function gland (a) Placenta Estrogen Initiates secretion of the milk (b) Corpus Estrogen Essential for luteum maintenance of endometrium (c) Leydig’s Androgen Initiates the cells production of sperms (d) Ovary FSH Stimulates follicular development and the secretion of estrogens

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Last Answer : (c) Leydig’s Androgen Initiates the cells production of sperms

Long-term thiazide therapy can cause hyperglycaemia by: A. Reducing insulin release B. Interfering with glucose utilization in tissues C. Increasing sympathetic activity D. Increasing corticosteroid secretion

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Last Answer : A. Reducing insulin release

Select the correct option describing gonadotropin activity in a normal pregnant female. (a) High level of FSH and LH stimulates the thickening of endometrium. (b) High level of FSH and LH facilitates implantation of the embryo. (c) High level of hCG stimulates the synthesis of estrogen and progesterone. (d) High level of hCG stimulates the thickening of endometrium.

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Last Answer : (c) High level of hCG stimulates the synthesis of estrogen and progesterone.

Select the condition for which 3 days treatment with pyrantel pamoate is recommended in place of single dose therapy for others: A. Ascariasis B. Ancylostomiasis C. Necatoriasis D. Enterobiasis

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Last Answer : C. Necatoriasis

A 40-year-old politician suffered from attacks of chest pain diagnosed as angina pectoris. He had a tense personality, resting heart rate was 96/min, blood pressure 170/104 mm Hg, but blood sugar level and lipid profile were normal. Select the most suitable antihypertensive for initial therapy in his case: A. Nifedipine B. Hydrochlorothiazide C. Atenolol D. Methyldopa

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Last Answer : C. Atenolol

Select the opioid antagonist that is preferred for long term opioid blockade therapy of post addicts: A. Nalorphine B. Naloxone C. Naltrexone D. Nalbuphine

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Select the most appropriate drug for regular prophylactic therapy in a 10 year old child who suffers from exercise induced asthma: A. Oral salbutamol B. Oral theophylline C. Inhaled sodium cromoglycate D. Inhaled salmeterol

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Select the correct statement in relation to drug therapy of migraine: A. Simple analgesics like paracetamol are ineffective in migraine B. Ergot alkaloids are used for prophylaxis as well as treatment of migraine attacks C. Use of ergot alkaloids is restricted to severe or resistant cases D. Ergot alkaloids should be given till 24 hours after an attack has subsided

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What is true of docetaxel: A. It is used as a reserve drug for refractory breast and ovarian cancer B. It is a selective estrogen receptor modulator used for breast cancer C. It is effective only in estrogen receptor positive breast cancer D. Both 'B' and 'C' are correct

Description : What is true of docetaxel: A. It is used as a reserve drug for refractory breast and ovarian cancer B. It is a selective estrogen receptor modulator used for breast cancer C. It is effective only in estrogen receptor positive breast cancer D. Both 'B' and 'C' are correct

Last Answer : A. It is used as a reserve drug for refractory breast and ovarian cancer