The NSAIDs aggravate the following diseases except: A. Hypertension B. Congestive heart failure C. Peptic ulcer D. Chronic gout

 The NSAIDs aggravate the following diseases except: A. Hypertension B. Congestive heart failure C. Peptic ulcer D. Chronic gout
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D. Chronic gout
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Allopurinol is indicated in the following category of chronic gout patients: A. Over producers of uric acid B. Under excretors of uric acid C. Those with tophi and/or renal urate stones D. All of the above

Description : Allopurinol is indicated in the following category of chronic gout patients: A. Over producers of uric acid B. Under excretors of uric acid C. Those with tophi and/or renal urate stones D. All of the above

Last Answer : D. All of the above

Select the drug which is used in chronic gout but is not uricosuric: A. Probenecid B. Phenylbutazone C. Sulfinpyrazone D. Allopurinol

Description : Select the drug which is used in chronic gout but is not uricosuric: A. Probenecid B. Phenylbutazone C. Sulfinpyrazone D. Allopurinol

Last Answer : D. Allopurinol

Streptokinase therapy of myocardial infarction is contraindicated in the presence of the following except: A. Peptic ulcer B. Ventricular extrasystoles C. History of recent trauma D. Severe hypertension

Description : Streptokinase therapy of myocardial infarction is contraindicated in the presence of the following except: A. Peptic ulcer B. Ventricular extrasystoles C. History of recent trauma D. Severe hypertension

Last Answer : B. Ventricular extrasystoles

In the treatment of chronic inflammatory diseases, the most important limitation of aspirin is: A. Acid-base and electrolyte disturbances B. Hypersensitivity and idiosyncratic reactions C. Gastric mucosal damage D. Salicylism

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Disease modifying antirheumatic drugs are indicated in rheumatoid arthritis: A. In place of NSAIDs in patients who donot tolerate the latter B. Along with NSAIDs in patients with progressive disease C. Only when NSAIDs fail to afford symptomatic relief D. In all patients irrespective of disease status/ concurrent medication

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Phenylbutazone should be used only in patients not responding to other nonsteroidal antiinflammatory drugs (NSAIDs) because: A. It has lower antiinflammatory efficacy than other NSAIDs B. It has potential to cause agranulocytosis C. It has weak analgesic action D. It alters the protein binding and metabolism of many drugs

Description : Phenylbutazone should be used only in patients not responding to other nonsteroidal antiinflammatory drugs (NSAIDs) because: A. It has lower antiinflammatory efficacy than other NSAIDs B. It has potential ... It has weak analgesic action D. It alters the protein binding and metabolism of many drugs

Last Answer : B. It has potential to cause agranulocytosis

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Last Answer : B. Amiodarone

Restriction of salt intake is generally recommended in (A) Diabetes mellitus (B) Hypertension (C) Cirrhosis of liver (D) Peptic ulcer

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Last Answer : B

A 35-year-old male presented with an attack of acute gout. He was treated with a 10 day course of naproxen. His blood uric acid level is high. What future line of treatment is most appropriate: A. No regular medication. Treat attacks of acute gout when they occur with naproxen. B. Regular long-term treatment with naproxen C. Regular long-term treatment with allopurinol D. Start with allopurinol + naproxen for 2 months followed by long-term allopurinol treatment

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Last Answer : B. Colchicine

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Last Answer : D. They are better tolerated

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Last Answer : B. Indomethacin

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Last Answer : D. Congestive heart failure

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Last Answer : Answer : C

The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent suppression of gastric acid enhances efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability

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Last Answer : A. It is indicated in all patients of peptic ulcer

The general principles in the use of hypnotics include the following except: A. A hypnotic may be used intermittently for upto 2-3 weeks in short-term insomnia due to emotional stress B. In patients with chronic insomnia a hypnotic should be used regularly C. All hypnotics aggravate sleep apnoea D. A hypnotic with slow elimination is preferred in patients with early morning awakening

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The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

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Last Answer : B. Vasopressor

Allopurinol has a therapeutic effect in the following conditions except: A. Radiotherapy induced hyperuricaemia B. Hydrochlorothiazide induced hyperuricaemia C. Acute gouty arthritis D. Kala-azar

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Last Answer : C. Acute gouty arthritis

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Last Answer : B. Prolongation of prothrombin time

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Last Answer : B. Bronchoconstriction

The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

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Last Answer : D. Ratio of H1:H2 blockade produced by the drug

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Peptic ulcer?

Description : Peptic ulcer?

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Last Answer : Answer : D

A bland diet is recommended in (A) Peptic ulcer (B) Atherosclerosis (C) Diabetes (D) Liver disease

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ibuprofen is contraindicated in -htn -dm -peptic ulcer

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Last Answer : Leakage aortic aneurysm

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Last Answer : C. Antiemetic for cancer chemotherapy

Choose the correct statement about colloidal bismuth subcitrate: A. It causes prolonged neutralization of gastric acid B. It has anti-H.pylori activity C. It relieves peptic ulcer pain promptly D. All of the above are correct

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Last Answer : B. It has anti-H.pylori activity

In peptic ulcer, antacids are now primarily used for: A. Prompt pain relief B. Ulcer healing C. Preventing ulcer relapse D. Control of bleeding from the ulcer

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Last Answer : A. Prompt pain relief

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Last Answer : B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding to H2 blockers

What is true of acid control therapy with H2 blockers: A. It generally heals duodenal ulcers faster than gastric ulcers B. It checks bleeding in case of bleeding peptic ulcer C. It prevents gastroesophageal reflux D. Both ‘A’ and ‘B’ are correct

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Last Answer : A. It generally heals duodenal ulcers faster than gastric ulcers

Vitamin K is indicated for the treatment of bleeding occurring in patients: A. Being treated with heparin B. Being treated with streptokinase C. Of obstructive jaundice D. Of peptic ulcer

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Last Answer : C. Of obstructive jaundice

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Description : For a patient of peptic ulcer, the safest nonopioid analgesic is: A. Celecoxib B. Diclofenac sodium C. Paracetamol D. Ibuprofen

Last Answer : C. Paracetamol

While prescribing a first generation H1 antihistaminic the patient should be advised to avoid: A. Driving motor vehicles B. Consuming processed cheese C. Strenuous physical exertion D. All of the above

Description : While prescribing a first generation H1 antihistaminic the patient should be advised to avoid: A. Driving motor vehicles B. Consuming processed cheese C. Strenuous physical exertion D. All of the above

Last Answer : A. Driving motor vehicles

The following H1 antihistaminic has additional anti 5-HT, anticholinergic, sedative and appetite stimulating properties: A. Promethazine B. Terfenadine C. Cyproheptadine D. Hydroxyzine

Description : The following H1 antihistaminic has additional anti 5-HT, anticholinergic, sedative and appetite stimulating properties: A. Promethazine B. Terfenadine C. Cyproheptadine D. Hydroxyzine

Last Answer : C. Cyproheptadine

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Description : High anticholinergic property is present in the following antihistaminic: A. Diphenhydramine B. Astemizole C. Cetirizine D. Terfenadine

Last Answer : A. Diphenhydramine

The action of histamine that is not mediated through H1 receptors is: A. Release of EDRF from vascular endothelium resulting in vasodilatation B. Direct action on vascular smooth muscle causing vasodilatation C. Bronchoconstriction D. Release of catecholamines from adrenal medulla

Description : The action of histamine that is not mediated through H1 receptors is: A. Release of EDRF from vascular endothelium resulting in vasodilatation B. Direct action on vascular smooth muscle causing vasodilatation C. Bronchoconstriction D. Release of catecholamines from adrenal medulla

Last Answer : B. Direct action on vascular smooth muscle causing vasodilatation

Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine

Description : Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine

Last Answer : C. 2-Thiazolyl ethylamine

Autacoids differ from hormones in that: A. Autacoids are involved only in the causation of pathological states B. Autacoids do not have a specific cell/tissue of origin C. Autacoids generally act locally at the site of generation and release D. Both ‘B’ and ‘C’ are correct

Description : Autacoids differ from hormones in that: A. Autacoids are involved only in the causation of pathological states B. Autacoids do not have a specific cell/tissue of origin C. Autacoids generally act locally at the site of generation and release D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

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Description : Probenecid has the following action(s): A. Uricosuric B. Analgesic C. Antiinflammatory D. Both ‘A’ and ‘C’

Last Answer : A. Uricosuric