Description : Nonsteroidal antiinflammatory drugs are more commonly used than colchicine in acute gout because: A. They are more effective B. They act more rapidly C. They have additional uricosuric action D. They are better tolerated
Last Answer : D. They are better tolerated
Description : Select the drug which is used in chronic gout but is not uricosuric: A. Probenecid B. Phenylbutazone C. Sulfinpyrazone D. Allopurinol
Last Answer : D. Allopurinol
Description : Probenecid has the following action(s): A. Uricosuric B. Analgesic C. Antiinflammatory D. Both ‘A’ and ‘C’
Last Answer : A. Uricosuric
Description : A 35-year-old male presented with an attack of acute gout. He was treated with a 10 day course of naproxen. His blood uric acid level is high. What future line of treatment is ... treatment with allopurinol D. Start with allopurinol + naproxen for 2 months followed by long-term allopurinol treatment
Last Answer : D. Start with allopurinol + naproxen for 2 months followed by long-term allopurinol treatment
Description : The patient taking the following non-steroidal antiinflammatory drug should be cautioned not to drive motor vehicle: A. Celecoxib B. Indomethacin C. Naproxen D. Diclofenac sodium
Last Answer : B. Indomethacin
Description : Select the first choice drug for acute gout: A. Cochicine B. Indomethacin C. Allopurinol D. Dexamethasone
Description : Select the drug which inhibits cyclooxygenase irreversibly: A. Aspirin B. Mephenamic acid C. Naproxen D. Diclofenac
Last Answer : A. Aspirin
Description : Selective COX-2 inhibitors differ from nonselective COX-1/COX-2 inhibitors in that they: A. Are antiinflammatory but not analgesic B. Donot bring down fever C. Have no renal effects D. Do not inhibit platelet aggregation
Last Answer : D. Do not inhibit platelet aggregation
Description : Phenylbutazone should be used only in patients not responding to other nonsteroidal antiinflammatory drugs (NSAIDs) because: A. It has lower antiinflammatory efficacy than other NSAIDs B. It has potential ... It has weak analgesic action D. It alters the protein binding and metabolism of many drugs
Last Answer : B. It has potential to cause agranulocytosis
Description : Sulfinpyrazone has the following action(s): A. Antiplatelet aggregatory B. Uricosuric C. Antiinflammatory D. Both ‘A’ and ‘B’
Last Answer : D. Both ‘A’ and ‘B’
Description : The most important dose-limiting adverse effect of colchicine is: A. Sedation B. Kidney damage C. Diarrhoea D. Muscle paralysis
Last Answer : C. Diarrhoea
Description : Select the drug that is neither bronchodilator nor antiinflammatory, but has antihistaminic and mast cell stabilizing activity: A. Sodium cromoglycate B. Ketotifen C. Beclomethasone dipropionate D. Chlorpheniramine
Last Answer : B. Ketotifen
Description : Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in ... with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure
Last Answer : Answers-2 Hyperuricaemia may be due to increased purine intake, urate production or reduced urate clearance, and is most commonly due to the latter. Therefore it can occur in association with enhanced ... . Many of the uricosuric drugs may be detrimental in renal failure and may not be effective.
Description : Allopurinol is indicated in the following category of chronic gout patients: A. Over producers of uric acid B. Under excretors of uric acid C. Those with tophi and/or renal urate stones D. All of the above
Last Answer : D. All of the above
Description : The NSAIDs aggravate the following diseases except: A. Hypertension B. Congestive heart failure C. Peptic ulcer D. Chronic gout
Last Answer : D. Chronic gout
Description : Which of the following is an efficacious antiinflammatory drug but a relatively weak inhibitor of cyclooxygenase: A. Nimesulide B. Paracetamol C. Ketoprofen D. Indomethacin
Last Answer : A. Nimesulide
Description : Which of the following drugs may be effective in the treatment of gouty arthritis by acting by two separate and distinct mechanisms? (a) Allopurinol (b) Probenecid (c) Colchicine (d) Indomethacin (e) Sulfinpyrazone
Last Answer : Ans: D
Description : Allopurinol has a therapeutic effect in the following conditions except: A. Radiotherapy induced hyperuricaemia B. Hydrochlorothiazide induced hyperuricaemia C. Acute gouty arthritis D. Kala-azar
Last Answer : C. Acute gouty arthritis
Description : Which one of the following drugs is not useful in dysmenorrhea? (a) Aspirin (b) Colchicine (c) Ibuprofen (d) Rofecoxib (e) Naproxen
Last Answer : Ans: B
Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition. (a) Acute gout (b) Burn (c) Toothache (d) Neuralgia
Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition: A. Acute gout B. Burn C. Toothache D. Neuralgi
Last Answer : B. Burn
Description : Which analgesic-antiinflammatory drug is more appropriate in musculo-skeletal disorder where pain is more prominent than inflammation: A. Ibuprofen B. Piroxicam C. Indomethacin D. Nimesulide
Last Answer : A. Ibuprofen
Description : Which drug can not be use in acute cholysystits Naproxen Morphine Mepriden Acetamenophin Perdoxyphen
Last Answer : Morphine
Description : The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug
Last Answer : D. Ratio of H1:H2 blockade produced by the drug
Description : What is true of disease modifying antirheumatic drugs: A. Their beneficial effect is manifest only after 1-3 months of therapy B. The disease does not recurr once they induce remission C. They are to be used life long D. Concurrent use of more than one disease modifying drug is not recommended
Last Answer : A. Their beneficial effect is manifest only after 1-3 months of therapy
Description : The following drug is used for cervical priming to facilitate labour: A. Oxytocin B. Clomiphene C. Progesterone D. Prostaglandin E2
Last Answer : D. Prostaglandin E2
Description : Select the β blocker which does not afford prophylaxis in migraine: A. Propranolol B. Timolol C. Atenolol D. Pindolol
Last Answer : D. Pindolol
Description : Select the H1 antihistaminic which is used topically in the nose for allergic rhinitis: A. Loratadine B. Cetirizine C. Fexofenadine D. Azelastine
Last Answer : D. Azelastine
Description : The preferred drug for controlling an acute exacerbation of ulcerative colitis is: A. Prednisolone B. Sulfasalazine C. Mesalazine D. Vancomycin
Last Answer : . Prednisolone
Description : Choose the correct statement about nonsteroidal antiinflammatory drugs (NSAIDs): A. NSAIDs attenuate hypoglycaemic action of sulfonylureas B. NSAIDs potentiate antihypertensive action of ACE inhibitors C. ... D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding
Last Answer : D. Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding
Description : If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is: A. Highly potent B. Highly efficacious C. Highly toxic D. Highly selective
Last Answer : D. Highly selective
Description : Colchicine is used mainly to treat (a) Gout (b) Arthiritis (c) Diabetes (d) Carcinomas (e) High blood pressure
Last Answer : Ans: A
Description : The following antiinflammatory analgesic has been cleared for pediatric use: A. Indomethacin B. Ibuprofen C. Ketorolac D. Piroxicam
Last Answer : B. Ibuprofen
Description : Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor
Last Answer : A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis
Description : Choose the action for which the dose of aspirin required is the lowest: A. Analgesic B. Antipyretic C. Antiinflammatory D. Antiplatelet aggregatory
Last Answer : D. Antiplatelet aggregatory
Description : The plasma half life of aspirin (along with salicylic acid released from it): A. Remains constant irrespective of dose B. Is longer for antiinflammatory doses compared to that for analgesic ... for antiinflammatory doses compared to that for analgesic dose D. Can be shortened by acidifying urine
Last Answer : B. Is longer for antiinflammatory doses compared to that for analgesic dose
Description : The following analgesic lacks antiinflammatory action: A. Paracetamol B. Ibuprofen C. Diclofenac sodium D. Piroxicam
Last Answer : A. Paracetamol
Description : Select the drug which tends to reverse insulin resistance by increasing cellular glucose transporters: A. Glibenclamide B. Rosiglitazone C. Acarbose D. Prednisolone
Last Answer : B. Rosiglitazone
Description : Prophylactic therapy of migraine: A. Is recommended in all cases B. Benefits upto 70% patients of moderate to severe migraine C. Needs to be continued lifelong without interruption D. Reduces the severity but increases the frequency of migraine attacks
Last Answer : B. Benefits upto 70% patients of moderate to severe migraine
Description : All of the following statements concerning an acute gouty arthritis attack are correct except (a) The diagonosis of gout is assured by a good therapeutic response to colchicines because no ... attack usually involves only one joint, most frequently the big toe (first metatarsophalangeal joint)
Description : While prescribing a first generation H1 antihistaminic the patient should be advised to avoid: A. Driving motor vehicles B. Consuming processed cheese C. Strenuous physical exertion D. All of the above
Last Answer : A. Driving motor vehicles
Description : The conventional H1 antihistaminics possess the following additional properties except: A. Local anaesthetic B. Vasopressor C. Antiarrhythmic D. Catecholamine potentiating
Last Answer : B. Vasopressor
Description : The following H1 antihistaminic has additional anti 5-HT, anticholinergic, sedative and appetite stimulating properties: A. Promethazine B. Terfenadine C. Cyproheptadine D. Hydroxyzine
Last Answer : C. Cyproheptadine
Description : High anticholinergic property is present in the following antihistaminic: A. Diphenhydramine B. Astemizole C. Cetirizine D. Terfenadine
Last Answer : A. Diphenhydramine
Description : The action of histamine that is not mediated through H1 receptors is: A. Release of EDRF from vascular endothelium resulting in vasodilatation B. Direct action on vascular smooth muscle causing vasodilatation C. Bronchoconstriction D. Release of catecholamines from adrenal medulla
Last Answer : B. Direct action on vascular smooth muscle causing vasodilatation
Description : Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine
Last Answer : C. 2-Thiazolyl ethylamine
Description : Autacoids differ from hormones in that: A. Autacoids are involved only in the causation of pathological states B. Autacoids do not have a specific cell/tissue of origin C. Autacoids generally act locally at the site of generation and release D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Disease modifying antirheumatic drugs are indicated in rheumatoid arthritis: A. In place of NSAIDs in patients who donot tolerate the latter B. Along with NSAIDs in patients with progressive ... to afford symptomatic relief D. In all patients irrespective of disease status/ concurrent medication
Last Answer : B. Along with NSAIDs in patients with progressive disease