Description : Estrogen replacement therapy for postmenopausal women is contraindicated in subjects with: A. Leg vein thrombosis B. Undiagnosed vaginal bleeding C. Migraine D. All of the above
Last Answer : D. All of the above
Description : Features of clindamycin include the following: A. It is primarily active against aerobic gram negative bacilli B. It can be used topically to treat infected acne vulgaris C. It is not absorbed orally D. It is used to treat pseudomembranous enterocolitis
Last Answer : B. It can be used topically to treat infected acne vulgaris
Description : Estrogen therapy in postmenopausal women has been implicated in increasing the risk of the following disorders except: A. Gall stones B. Osteoporosis C. Endometrial carcinoma D. Breast cancer
Last Answer : B. Osteoporosis
Description : Parenteral testosterone therapy in a boy can cause the following adverse effects except: A. Gynaecomastia B. Acne C. Cholestatic jaundice D. Precocious puberty
Last Answer : C. Cholestatic jaundice
Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance
Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs
Description : Clomiphene citrate is indicated for the following condition/conditions: A. Female infertility due to anovular cycles B. Male infertility due to oligozoospermia C. Endometriosis D. Both 'A' and 'B'
Last Answer : D. Both 'A' and 'B'
Description : Danazol is used for the following disorders except: A. Amenorrhoea B. Endometriosis C. Fibrocystic breast disease D. Precocious puberty in male children
Last Answer : A. Amenorrhoea
Description : Select the correct statement in relation to drug therapy of migraine: A. Simple analgesics like paracetamol are ineffective in migraine B. Ergot alkaloids are used for prophylaxis as well as treatment ... resistant cases D. Ergot alkaloids should be given till 24 hours after an attack has subsided
Last Answer : C. Use of ergot alkaloids is restricted to severe or resistant cases
Description : Addition of a progestin for 10-12 days every month to cyclic estrogen replacement therapy during menopause is recommended because the progestin: A. Prevents osteoporosis B. Prevents irregular bleeding C. Blocks increased risk of endometrial carcinoma D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Select the progestin preparation for coadministration with estrogen for hormone replacement therapy that does not counteract the beneficial effect of the latter on lipid profile due to lack of ... oral progesterone B. Norethindrone C. Lynestrenol D. Medroxyprogesterone acetate (p. 281-282)
Last Answer : Select the indication for which a progestin is used alone without combining with an estrogen: A. Threatened abortion B. Dysfunctional uterine bleeding C. Hormone replacement therapy D. Premenstrual tension
Description : Select the correct statement about tibolone: A. It is an antiestrogen used for palliative treatment of carcinoma breast B. It is an estrogenic + progestational steroid used for hormone replacement ... for male pattern baldness D. It is a nonsteroidal estrogen used topically for senile vaginitis
Last Answer : B. It is an estrogenic + progestational steroid used for hormone replacement therapy in postmenopausal women
Description : Select the compound which used for hormone replacement therapy in postmenopausal women serves the purpose of both estrogen and progestin with weak androgenic activity: A. Tibolone B. Mestranol C. Desogestrel D. Gestodene
Last Answer : A. Tibolone
Description : The daily dose of estrogen for hormone replacement therapy in postmenopausal women is: A. Same as for contraception B. Higher than that for contraception C. Lower than that for contraception D. Variable depending on the age of the woman
Last Answer : C. Lower than that for contraception
Description : The estrogen commonly used for hormone replacement therapy in menopausal women is: A. Ethinylestradiol B. Estradiol benzoate C. Diethylstilbestrol D. Conjugated estrogens
Last Answer : D. Conjugated estrogen
Description : Addition of a progestin for 10-12 days each month to estrogen replacement therapy in menopausal women is recommended because the progestin: A. Blocks the increased risk of myocardial ... vulval atrophy occurring in postmenopausal women D. Enhances the metabolic benefits of estrogen treatment
Last Answer : The estrogen commonly used for hormone replacement therapy in menopausal women is: A. Ethinylestradiol B. Estradiol benzoate C. Diethylstilbestrol D. Conjugated estrogens
Description : Transdermal estradiol differs from oral estrogen therapy in that it: A. Causes less induction of hepatic synthesis of clotting factors B. Does not inhibit FSH secretion C. Does not affect vaginal cytology D. All of the above are correct
Last Answer : A. Causes less induction of hepatic synthesis of clotting factors
Description : Empiric therapy with chloramphenicol is valid in the following conditions except: A. Urinary tract infection B. Pelvic abscess C. Endophthalmitis D. Meningitis in a 4-year-old child
Last Answer : A. Urinary tract infection
Description : Thrombolytic therapy is indicated in the following conditions except: A. Acute myocardial infarction B. Stroke due to cerebral thrombosis C. Deep vein thrombosis D. Large pulmonary embolism
Last Answer : B. Stroke due to cerebral thrombosis
Description : Along with effective antimicrobial therapy, corticosteroids are indicated in the following infective conditions except: A. Tubercular meningitis B. Severe P. carinii pneumonia in AIDS patient C. Herpes simplex keratitis D. Erythema nodosum leprosum
Last Answer : C. Herpes simplex keratitis
Description : Thyroxine therapy is indicated in the following conditions except: A. Euthyroid status with raised TSH level B. Diffuse nontoxic goiter C. Nonfunctional thyroid nodule D. Benign functioning thyroid nodule
Last Answer : C. Nonfunctional thyroid nodule
Description : Indications of tricyclic antidepressants include the following except: A. Attention deficit-hyperactive disorder in children B. Mania C. Prophylaxis of migraine D. Panic disorder
Last Answer : B. Mania
Description : 5-HT appears to play a role in the following except: A. Regulation of normal BP B. Regulation of intestinal peristalsis C. Haemostasis D. Causation of migraine
Last Answer : A. Regulation of normal BP
Description : Follicular dilation involving the nose and portions of the cheeks, erythema, papules, and pustules are classic signs of this dermatologic disorder. A. acne cosmetica B. acne pustulosa C. acne rosacea D. acne vulgaris
Last Answer : Ans: C
Description : An acute eruption of intensely itchy papules or wheals is called A. acne vulgaris B. pityriasis rosea C. psoriasis D. urticaria (hives.
Last Answer : Ans: D
Description : Choose the most suitable antihypertensive drug for a 45-year-old male company executive who has a travelling job. His blood pressure is 160/100 mm Hg, and he is a diabetic ... → rebound hypertension. Hydrochlorothiazide: May worsen diabetes; more likely to produce weakness, fatigue and impotenc
Last Answer : B. Enalapril
Description : In which of the following conditions estrogen is not the primary drug but is added to progestin as adjuvant: A. Dysfunctional uterine bleeding B. Menopausal syndrome C. Osteoporosis D. Atrophic vaginitis
Last Answer : A. Dysfunctional uterine bleeding
Description : The distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile
Last Answer : C. It has additional androgenic acitivity
Description : he distinctive features of desogestrel include the following except: A. It is a prodrug B. It has both strong progestational and strong antiovulatory activities C. It has additional androgenic acitivity D. It does not counteract the beneficial effect of estrogen on lipid profile
Description : The following is true of raloxifene except: A. It acts as an estrogen agonist in bone B. It exerts estrogen antagonistic action on endometrium C. It increases risk of developing breast cancer D. It can induce/aggravate menopausal hot flushes
Description : The most important indication of mifepristone is: A. Endometriosis B. Cushing's syndrome C. First term abortion D. Second term abortion
Last Answer : C. First term abortion
Description : The following is/are beneficial in endometriosis: A. Norethindrone B. Nafarelin C. Danazol D. All of the above
Description : The primary indication of tamoxiphen citrate is: A. Female infertility B. Endometrial carcinoma C. Carcinoma breast D. Endometriosis
Last Answer : C. Carcinoma breast
Description : Danazol produces the following side effects in premenopausal women except: A. Acne B. Menorrhagia C. Amenorrhoea D. Hot flashes
Last Answer : B. Menorrhagia
Description : The following is true of multidrug therapy of leprosy except: A. It has been highly successful in paucibacillary but not in multibacillary cases B. Relapse rate is very low in both paucibacillary ... use once a month D. Prevalence of lepra reaction is not higher compared to dapsone monotherapy
Last Answer : A. It has been highly successful in paucibacillary but not in multibacillary cases
Description : Combination therapy with two (or more) antimicrobials is superior to monotherapy with any single effective drug in case of the following diseases except: A. Typhoid fever B. Leprosy C. AIDS D. Subacute bacterial endocarditis
Last Answer : A. Typhoid fever
Description : Bacteriostatic drugs are unlikely to effect cure of bacterial infection in the following category of patients except: A. Diabetic patients B. Patients with allergic disorders C. Patients on corticosteroid therapy D. Subacute bacterial endocarditis patient
Last Answer : B. Patients with allergic disorders
Description : The following is true of anti-H.pylori therapy except: A. It is indicated in all patients of peptic ulcer B. Resistance to any single antimicrobial drug develops rapidly C. Concurrent ... efficacy of the regimen D. Colloidal bismuth directly inhibits H.pylori but has poor patient acceptability
Last Answer : A. It is indicated in all patients of peptic ulcer
Description : Streptokinase therapy of myocardial infarction is contraindicated in the presence of the following except: A. Peptic ulcer B. Ventricular extrasystoles C. History of recent trauma D. Severe hypertension
Last Answer : B. Ventricular extrasystoles
Description : The following is true of heparin except: A. Sudden stoppage of continuous heparin therapy causes rebound increase in blood coagulability B. High doses of heparin inhibit platelet aggregation ... active circulating anticoagulant D. Heparin clears lipemic plasma in vivo but not in vitro
Last Answer : C. Heparin is the physiologically active circulating anticoagulant
Description : Choose the correct statement about iron therapy: A. Haemoglobin response to intramuscular iron is faster than with oral iron therapy B. Iron must be given orally except in pernicious anaemia C. ... iron therapy must be given during pregnancy D. Infants on breastfeeding do not require medicinal iron
Last Answer : C. Prophylactic iron therapy must be given during pregnancy
Description : The principles of antihypertensive drug usage enunciated in JNC VI and WHO-ISH guidelines include the following except: A. Therapy for grade I and II hypertension should be initiated with a single drug ... initially fails to lower BP, it should be replaced by a drug/combination from another class
Last Answer : C. All subjects with BP higher than 140/90 mmHg should be put on antihypertensive medication immediately
Description : The antihypertensive action of calcium channel blockers is characterized by the following except: A. Delayed onset; blood pressure starts falling after 1–2 weeks therapy B. Lack of central side effects C. No compromise of male sexual function D. Safety in peripheral vascular diseases
Last Answer : A. Delayed onset; blood pressure starts falling after 1–2 weeks therapy
Description : The following apply to use of spironolactone in CHF except: A. It is indicated only in NYHA class III/IV cases as additional drug to conventional therapy B. It affords prognostic benefit in ... by ACE inhibitors C. It helps overcome refractoriness to diuretics D. It affords rapid symptomatic relief
Last Answer : D. It affords rapid symptomatic relief
Description : ndications of piracetam include the following except: A. Apnoea in preterm infant B. Learning defects in children C. Confusional states in the elderly D. Memory impairment following electroconvulsive therapy
Last Answer : A. Apnoea in preterm infant
Description : The following is true of topiramate except: A. It is a broad spectrum antiepileptic drug B. It inhibits the enzyme carbonic anhydrase C. It is used as add-on therapy in refractory partial seizures D. It is not effective in generalized tonic-clonic seizures
Last Answer : D. It is not effective in generalized tonic-clonic seizures
Description : Indications of centrally acting muscle relaxants include all of the following except: A. Balanced anaesthesia B. Traumatic muscle spasms C. Torticollis D. Electroconvulsive therapy
Last Answer : A. Balanced anaesthesia
Description : Side effects of cyclic progestin therapy include the following except: A. Headache B. Gastroesophageal reflux C. Breast dyscomfort D. Irregular bleeding
Last Answer : D. Irregular bleeding
Description : Benefits of tamoxifen citrate therapy include the following except: A. Reduction in recurrence rate of breast cancer B. Improved bone mass C. Suppression of menopausal hot flushes D. Improved lipid profile
Last Answer : C. Suppression of menopausal hot flushes
Description : The calcium channel blocker used for prophylaxis of migraine but not for angina pectoris is: A. Verapamil B. Diltiazem C. Flunarizine D. Amlodipine
Last Answer : C. Flunarizine
Description : The most important risk in the use of sumatriptan for treatment of migraine is: A. Precipitation of seizures B. Precipitation of psychosis C. Development of hypertension D. Coronary vasospasm
Last Answer : D. Coronary vasospasm