Fluconazole differs from ketoconazole in that:
A. It is not active by the oral route
B. It is a more potent inhibitor of drug metabolism
C. It is not effective in cryptococcal meningitis
D. It is unlikely to produce anti-androgenic
side effects

1 Answer

Answer :

D. It is unlikely to produce anti-androgenic
side effects

Related questions

Description : Fluconazole is more effective than intraconazole in the following systemic fungal disease: A. Pulmonary histoplasmosis B. Cryptococcal meningitis C. Nonmeningeal blastomycosis D. Disseminated sporotrichosis

Last Answer : B. Cryptococcal meningitis

Description : Fluconazole offers the following advantage(s) over ketoconazole: A. It is longer acting B. Its absorption from stomach is not dependent on gastric acidity C. It produces fewer side effects D. All of the above

Last Answer : D. All of the above

Description : The only azole antifungal drug which has some activity against moulds like Aspergillus is: A. Itraconazole B. Fluconazole C. Miconazole D. Ketoconazole

Last Answer : A. Itraconazole

Description : Choose the azole antifungal drug which is used only topically: A. Ketoconazole B. Fluconazole C. Itraconazole D. Econazole

Last Answer : D. Econazole

Description : Select the antifungal drug which is administered only by the oral route: A. Amphotericin B B. Ketoconazole C. Griseofulvin D. Tolnaftate

Last Answer : C. Griseofulvin

Description : The progestin used in combined oral contraceptive pill is a 19-nortestosterone derivative because: A. They have potent antiovulatory action of their own B. They do not produce any metabolic effects C. They produce fewer side effects D. They are longer acting

Last Answer : A. They have potent antiovulatory action of their own

Description : The following is applicable to itraconazole except: A. It has largely replaced ketoconazole for treatment of systemic mycosis B. It does not inhibit human steroid hormone synthesis C. It is ... the treatment of fungal meningitis D. It can interact with terfenadine to produce ventricular arrhythmias

Last Answer : C. It is preferred for the treatment of fungal meningitis

Description : Carbimazole differs from propylthiouracil in that: A. It is dose to dose less potent B. It has a shorter plasma half life C. It does not produce an active metabolite D. It does not inhibit peripheral conversion of thyroxine to triiodothyronine

Last Answer : D. It does not inhibit peripheral conversion of thyroxine to triiodothyronine

Description : Sulbactam differs from clavulanic acid in that: A. It is not a progressive inhibitor of β-lactamase B. It does not inhibit β-lactamase produced by gram negative bacilli C. It is quantitatively more potent D. It per se inhibits N.gonorrhoeae

Last Answer : D. It per se inhibits N.gonorrhoeae

Description : The following statement is true about ketoconazole except: A. It is less toxic than amphotericin B B. It produces a slower response than amphotericin B in systemic mycosis C. Given orally it is the first line treatment for vaginal candidiasis D. It is not effective in fungal meningitis

Last Answer : C. Given orally it is the first line treatment for vaginal candidiasis

Description : Pentazocine differs from morphine in that: A. It is inactive by the oral route B. It does not produce physical dependence C. It has a lower ceiling of analgesic effect D. Its action is not blocked by naloxone

Last Answer : C. It has a lower ceiling of analgesic effec

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : A. They have potent antiovulatory action of their own

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : B. They produce many side effects

Description : Enalapril differs from captopril in the following features except: A. It is dose to dose more potent B. Its oral absorption is not affected by food in stomach C. It acts more rapidly D. It has longer duration of action

Last Answer : D. Lisinopri

Description : Mifepristone possesses the following activities: A. Potent antiprogestin + weak androgenic B. Potent antiprogestin + weak antiglucocorticoid C. Potent antiestrogenic + weak antiprogestin D. Potent antiestrogenic + weak glucocorticoid

Last Answer : Mifepristone possesses the following activities: A. Potent antiprogestin + weak androgenic B. Potent antiprogestin + weak antiglucocorticoid C. Potent antiestrogenic + weak antiprogestin D. Potent antiestrogenic + weak glucocorticoid

Description : The 19-Norprogestins differ from progesterone derivatives in that they: A. Have potent antiovulatory activity B. Have no additional androgenic activity C. Have no additional estrogenic activity D. Are preferred for use in endometriosi

Last Answer : A. Have potent antiovulatory activity

Description : Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor

Last Answer : A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis

Description : Out of two anticholinesterases, drug X' is a tertiary amine while drug Y' is a quarternary ammonium compound. Then: A. Drug X' is likely to be more potent than Y' B. Drug X' will be more ... a miotic C. Drug Y' will be completely metabolized in the body D. Drug Y' will produce CNS effects

Last Answer : B. Drug ‘X’ will be more suitable to be used as a miotic

Description : Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity

Last Answer : A. Exerts depressant effects on the CNS at relatively low doses

Description : The following second generation anti-histaminic is not likely to produce ventricular arrhythmias when administered along with ketoconazole: A. Mizolastine B. Ebastine C. Terfenadine D. Astemizole

Last Answer : A. Mizolastine

Description : Olanzapine has the following features except: A. It is an antipsychotic drug with weak D2 receptor blocking action B. It has potent 5-HT2 blocking and antimuscarinic actions C. It lowers seizure threshold D. It produces prominent extrapyramidal side effects

Last Answer : D. It produces prominent extrapyramidal side effect

Description : Ranitidine differs from cimetidine in the following respect: A. It is less potent B. It is shorter acting C. It does not have antiandrogenic action D. It produces more CNS side effect

Last Answer : C. It does not have antiandrogenic action

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

Description : Which of the following is a nonselective but very potent and efficacious bonchodilator that is not active by the oral route? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol

Last Answer : Ans: C

Description : What is true about use of amphotericin B in kala azar: A. It is currently the drug of choice B. It is more effective than ketoconazole C. It is indicated only in cases not responding to sodium stibogluconate D. Both 'B' and 'C' are correct

Last Answer : D. Both 'B' and 'C' are correct

Description : In the treatment of parkinsonism, bromocriptine differs from levodopa in the following respects except: A. It does not need conversion to an active metabolite B. It has a longer duration of ... with little/antagonistic action on D1 receptors D. It does not produce behavioral/psychiatric side effect

Last Answer : D. It does not produce behavioral/psychiatric side effects

Description : Select the progestin preparation for coadministration with estrogen for hormone replacement therapy that does not counteract the beneficial effect of the latter on lipid profile due to lack of ... oral progesterone B. Norethindrone C. Lynestrenol D. Medroxyprogesterone acetate (p. 281-282)

Last Answer : Select the indication for which a progestin is used alone without combining with an estrogen: A. Threatened abortion B. Dysfunctional uterine bleeding C. Hormone replacement therapy D. Premenstrual tension

Description : Tinidazole differs from metronidazole in that: A. It is not active against anaerobic bacteria B. It has a broader spectrum of activity C. It has a longer elimination half life D. It has better oral absorption

Last Answer : C. It has a longer elimination half life

Description : Pentazocine differs from morphine in that (a) It is inactive by the oral route (b) It does not produce physical dependence (c) It has a lower ceiling of analgesic effect (d) Its action is not blocked by naloxone

Last Answer : Ans: C

Description : A progestin and an estrogen are combined in oral contraceptive pill because: A. The estrogen blocks the side effects of the progestin B. The progestin blocks the side effects of the estrogen C. Both synergise to suppress ovulation D. Both synergise to produce hostile cervical mucus

Last Answer : C. Both synergise to suppress ovulation

Description : Choose the correct statement(s) about cefepime: A. It is a 4th generation cephalosporin B. It is active against many bacteria resistant to 3rd generation celphalosporins C. It is active by the oral route D. Both 'A' and 'B' are correct

Last Answer : D. Both 'A' and 'B' are correct

Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because: A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents ... the microbes of the normal gut flora D. It is a potent tetracycline and inhibits

Last Answer : A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low

Description : Pyridostigmine differs from neostigmine in that (a) More potent orally (b) Longer acting (c) Less muscarinic side effects (d) All of the above

Last Answer : Ans: B

Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

Last Answer : B. It is longer acting

Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

Last Answer : B. It is longer acting

Description : Cimetidine interacts with more drugs than ranitidine because; a) It is subjected to greater first pass metabolism b) It is a more potent enzyme inducer c) It is a more potent enzyme inhibitor d) It has better oral absorption

Last Answer : c) It is a more potent enzyme inhibitor  

Description : Features of atorvastatin include the following: A. Dose to dose most potent HMG-CoA reductase inhibitor B. Higher ceiling of LDL-cholesterol lowering action than lovastatin C. Antioxidant property D. All of the above

Last Answer : D. All of the above

Description : Choose the most potent and most efficacious LDLcholesterol lowering HMG-CoA reductase inhibitor: A. Lovastatin B. Simvastatin C. Pravastatin D. Atorvastatin

Last Answer : D. Atorvastatin

Description : Choose the correct statement about ondansetron: A. It is a dopamine D2 receptor antagonist B. It suppresses postoperative nausea and vomiting C. It is the most effective antiemetic for motion sickness D. It is not effective by oral route

Last Answer : B. It suppresses postoperative nausea and vomitin

Description : Zolpidem differs from diazepam in that: A. It is safer in overdose than diazepam B. Its hypnotic action shows little fading on repeated nightly use C. It causes more marked suppression of REM sleep D. It has more potent muscle relaxant action

Last Answer : B. Its hypnotic action shows little fading on repeated nightly use

Description : Dexamethasone differs from prednisolone in that it is: A. Longer acting B. More potent C. More selective D. All of the above

Last Answer : D. All of the above

Description : riiodothyronine differs from thyroxine in that: A. It is more avidly bound to plasma proteins B. It has a shorter plasma half life C. It is less potent D. It has a longer latency of action

Last Answer : B. It has a shorter plasma half life

Description : 17.2 Triiodothyronine differs from thyroxine in that: A. It is more avidly bound to plasma proteins B. It has a shorter plasma half life C. It is less potent D. It has a longer latency of action (

Last Answer : B. It has a shorter plasma half life

Description : Dihydroergotamine (DHE) differs from ergotamine in the following respect: A. It is a more potent oxytocic B. It has antiemetic property C. It has high oral bioavailability D. It is a more potent α adrenergic blocker and less potent vasoconstrictor

Last Answer : D. It is a more potent α adrenergic blocker and less potent vasoconstrictor

Description : Choose the correct statement about codeine: A. It has a lower oral: parenteral activity ratio than morphine B. It is devoid of abuse liability C. It is a weaker analgesic than morphine D. It is a more potent antitussive than morphine

Last Answer : C. It is a weaker analgesic than morphine

Description : Adverse effects of ketoconazole include the following except: A. Gynaecomastia B. Oligozoospermia C. Kidney damage D. Menstrual irregularities

Last Answer : C. Kidney damage

Description : The drug of choice for Kala azar is: A. Pentamidine B. Amphotericin B C. Sodium stibogluconate D. Ketoconazole

Last Answer : C. Sodium stibogluconat

Description : Select the drug that is fungicidal and acts by inhibiting fungal squalene epoxidase enzyme: A. Ketoconazole B. Terbinafine C. Tolnaftate D. Hamycin

Last Answer : B. Terbinafine

Description : The drug of choice for monilial diarrhoea is: A. Flucytosine B. Nystatin C. Natamycin D. Ketoconazole

Last Answer : B. Nystatin

Description : The following prokinetic drug has been implicated in causing serious ventricular arrhythmias, particularly in patients concurrently receiving erythromycin or ketoconazole: A. Domperidone B. Cisapride C. Mosapride D. Metoclopramide

Last Answer : B. Cisapride