Description : What is the role of NADP reductase enzyme in proton gradient development? -Biology
Last Answer : answer:
Description : For reduction enzyme HMG-CoA reductase requires cofactor: (A) NADPH (B) NADP (C) NAD (D) FAD
Last Answer : Answer : A
Description : Retinal is reduced to retinol by retinene reductase in presence of the coenzyme (A) NAD+ (B) NADP+ (C) NADH + H+ (D) NADPH + H+
Last Answer : Answer : C
Description : Retinol and retinal are interconverted requiring dehydrogenase or reductase in the presence of (A) NAD or NADP (B) NADH + H+ (C) NADPH (D) FAD
Description : Cancer cells may become resistant to amethopterin by (A) Developing mechanisms to destroy amethopterin (B) Amplification of dihydrofolate reducatse gene (C) Mutation in the dihydrofolate reductase ... is no longer inhibited by amethopterin (D) Developing alternate pathway of thymidylate synthesis
Last Answer : Answer : B
Description : Methotrexate blocks the synthesis of thymidine monophosphate by inhibiting the activity of the enzyme: (A) Dihydrofolate reductase (B) Orotate phosphoribosyl transferase (C) Ribonucleotide reductase (D) Dihydroorotase
Description : Conversion of deoxyuridine monophosphate to thymidine monophosphate is catalysed by the enzyme: (A) Ribonucleotide reductase (B) Thymidylate synthetase (C) CTP synthetase (D) Orotidylic acid decarboxylase
Description : In biosynthesis of cholesterol triparanol inhibits the activity of the enzyme: (A) ∆24 Reductase (B) Oxidosqualene-lanosterol cyclase (C) Isomerase (D) Squalene epoxidase ENZYMES 155
Description : In the biosynthesis of cholesterol, the rate limiting enzyme is (A) Mevalonate kinase (B) HMG-CoA synthetase (C) HMG-CoA reductase (D) Cis-prenyl transferase
Description : Synthesis of polyunsaturated fatty acids involves the enzyme systems: (A) Acyl transferase and hydratase (B) Desaturase and elongase (C) Ketoacyl-CoA reductase and hydratase (D) Dihydroxyacetone phosphate
Description : Conversion of fructose to sorbitol is catalysed by the enzyme: (A) Sorbitol dehydrogenase (B) Aldose reductase (C) Fructokinase (D) Hexokinase
Description : The enzyme involved in essential pentosuria is (A) Reductase (B) Hydroxylase (C) Isomerase (D) Racemase
Description : An enzyme required for the synthesis of ketone bodies as well as cholesterol is (A) Acetyl CoA carboxylase (B) HMG CoA synthetase (C) HMG CoA reductase (D) HMG CoA lyase
Description : A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is (A) Fluvastatin (B) Cerivastatin (C) Lovastatin (D) Somatostatin
Last Answer : (C) Lovastatin
Description : Trimethoprim inhibits bacteria without affecting mammalian cells because: A. It does not penetrate mammalian cells B. It has high affinity for bacterial but low affinity for mammalian dihydrofolate ... bacterial folate synthetase as well as dihydrofolate reductase enzymes D. All of the above
Last Answer : B. It has high affinity for bacterial but low affinity for mammalian dihydrofolate reductase enzyme
Description : Conversion of testosterone to dihydrotestosterone by the enzyme 5α-reductase is required for the following actions except: A. Formation of male external genitalia in the foetus B. Prostatic hypertrophy in elderly males C. Pubertal changes in the male adolescent D. Spermatogenesis
Last Answer : D. Spermatogenesis
Description : Name the given reaction and enzyme involved in it. `alpha`-etoglutaric acid `+NH_(4)^(+)+NADPH overset("Enzyme")to"glutamate"+H_(2)O+NADP`
Last Answer : Name the given reaction and enzyme involved in it. `alpha`-etoglutaric acid `+NH_(4)^(+)+NADPH overset("Enzyme")to"glutamate"+H_(2)O+NADP`
Description : A cofactor in the conversion of dihydroorotate to orotic acid, catalysed by the enzyme dihydroorotate dehydrogenase is (A) FAD (B) FMN (C) NAD (D) NADP
Description : Thyroproxidase requires hydrogen peroxide as oxidizing agent. The H2O2 is produced by (A) FADH2 dependent enzyme (B) NADH dependent enzyme (C) NADP dependent enzyme (D) NADPH dependent enzyme
Last Answer : Answer : D
Description : The example of hydrogen transferring Co-enzyme is: (A) B6-PO4 (B) NADP+ (C) TPP (D) ATP
Description : Group transferring Co-enzyme is (A) CoA (B) NAD+ (C) NADP+ (D) FAD+
Description : Malic enzyme convers malic acid, in the presence of NADP+ to Pyruvic acid. This reaction is a/an (A) Decarboxylation (B) Decarboxylation and Dehydrogenation (C) Dehydrogenation (D) Oxidation
Description : Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+
Description : The following co-enzyme is needed for the oxidative decarboxylation of ketoacids: (A) NADP+ (B) TPP (C) Folate coenzyme (D) Biotin coenzyme
Last Answer : B
Description : Amplification of dihydrofolate reductase gene in a cancer cell makes the cell (A) Susceptible to folic acid deficiency (B) Less malignant (C) Resistant to amethopterin therapy (D) Responsive to amethopterin therapy
Description : Amplification of dihydrofolate reductase gene may be brought about by (A) High concentrations of folic acid (B) Deficiency of folic acid (C) Low concentration of thymidylate (D) Amethopterin
Description : All of the following statements about thioredoxin reductase are true except: (A) It requires NADH as a coenzyme (B) Its substrates are ADP, GDP, CDP and UDP (C) It is activated by ATP (D) It is inhibited by dADP
Description : Conversion of uridine diphosphate into deoxyuridine diphosphate requires all the following except (A) Ribonucleotide reductase (B) Thioredoxin (C) Tetrahydrobiopterin (D) NADPH
Description : Ceruloplasmin shows the activity (A) As ferroxidase (B) As reductase (C) As ligase (D) As transferase
Description : Selenium is a constituent of (A) Glutathione reductase (B) Glutathione peroxidase (C) Catalase (D) Superoxide dismutase
Description : Which mineral element controls the activity of Nitrate reductase ? (A) Fe (B) Mo (C) Zn (D) Ca
Description : Pyruvate dehydrogenase is a/an (A) Isomerase (B) Lyase (C) Ligase (D) Oxido reductase
Description : HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids
Description : The activity of HMG-CoA reductase is inhibited by (A) A fungal inhibitor mevastatin (B) Probucol (C) Nicotinic acid (D) Clofibrate
Description : Cholesterol by a feed back mechanism inhibits the activity of (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Thilase (D) Mevalonate kinase
Description : HMG-CoA is converted to mevalonate by reduction catalysed by (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Mevalonate kinase (D) Thiolase
Description : Two molecules of acetyl-CoA condense to form acetoacetyl-CoA catalysed by (A) Thiolase (B) Kinase (C) Reductase (D) Isomerase
Description : The rate limiting reaction in the lipogenic pathway is (A) Acetyl-CoA carboxylase step (B) Ketoacyl synthase step (C) Ketoacyl reductase step (D) Hydratase step
Description : Retinal is converted into retinoic acid in the presence of (A) Retinal oxidase (B) Retinal carboxylase (C) Retinene reductase(D) Spontaneously
Description : FAD is a coenzyme for (A) Succinate dehydrogenase (B) Glycerol-3-phosphate dehydrogenase (C) Sphingosine reductase (D) All of these
Description : Retinal is reduced to retinol in intestinal mucosa by a specific retinaldehyde reductase utilising (A) NADPH + H+ (B) FAD (C) NAD (D) NADH + H+
Description : The rage limiting step cholesterol biosynthesis is (A) Squalene synthetase (B) Mevalonate kinase (C) HMG CoA synthetase (D) HMG CoA reductase
Description : Lovastatin is a (A) Competitive inhibitor of acetyl CoA carboxylase (B) Competitive inhibitor of HMG CoA synthetase (C) Non-competitive inhibitor of HMG CoA reductase (D) Competitive inhibitor of HMG CoA reductase
Description : Insulin degradation of disulfide bond formation is effected by (A) Pyruvate dehydrogenase (B) Xylitol reductase (C) Gutathione reductase (D) Xanthine oxidase
Description : Oxaloacetate is converted to aspartic acid by (A) Reductase (B) Oxidase (C) Transminase (D) Catalase
Description : Activity of ceruloplasmin shown in vitro: (A) Reductase (B) Hydrolase (C) Ligase (D) Oxidase
Description : Neogenesis of methyl group is (A) The availability of methyl group form δ adenosyl methionine (B) The availability of methyl group from betaine (C) Interaction between N5 N10 methylene tetra hydrofolate with a NAD+ dependent reductase (D) Availability of methyl group from methyl B12
Description : The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL
Description : A 70-year-old man has severe urinary hesitancy associated with benign prostatic hyperplasia. He has tried alpha blockers with little relief. His physician recommends a drug that blocks 5a - reductase in ... prescription for (a) Atropine (b) Clonidine (c) Hydralazine (d) Neostigmine (e) Propranolol
Last Answer : Ans: B
Description : Molybdenum deficiency affects the activity of – (1) All of the given options (2) Chlorate reductase (3) Nitrogenase (4) Nitrate reductase
Last Answer : (4) Nitrate reductase Explanation: Numerous investigators have shown that nitrate nitrogen accumulates in higher plants and fungi which are deficient in molybdenum. In molybdenum-deficient plants grown in the ... in the decrease of free amino acids in the plants in comparison to normal plants.