Morphine produces analgesia by acting at: A. Peripheral pain receptors B. A spinal site C. Supraspinal sites D. Both spinal and supraspinal sites

Morphine produces analgesia by acting at:
A. Peripheral pain receptors
B. A spinal site
C. Supraspinal sites
D. Both spinal and supraspinal sites
by

1 Answer

Answer :

D. Both spinal and supraspinal sites
by

Related questions

Morphine produces analgesia by acting at (a) Peripheral pain receptors (b) A spinal site (c) Suspraspinal sites (d) Both (b) and (c)

Description : Morphine produces analgesia by acting at (a) Peripheral pain receptors (b) A spinal site (c) Suspraspinal sites (d) Both (b) and (c)

Last Answer : Ans: B

Aspirin produces analgesia by (a) Preventing sensitization of peripheral pain receptors (b) Affecting gating of pain impulses at spinal level (c) Raising pain threshold at subcortical level (d) Both (a) and (b)

Description : Aspirin produces analgesia by (a) Preventing sensitization of peripheral pain receptors (b) Affecting gating of pain impulses at spinal level (c) Raising pain threshold at subcortical level (d) Both (a) and (b)

Last Answer : Ans: D

Aspirin produces analgesia by: A. Preventing sensitization of peripheral pain receptors B. Affecting gating of pain impulses at spinal level C. Raising pain threshold at subcortical level D. Both ‘A’ and ‘C’ are correct

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Last Answer : D. Both ‘A’ and ‘C’ are correct

The following are true about pain: a. in disseminated cancer can be effectively relieved by hypophysectomy b. does not ascend through the dorsal column of the spinal cord c. is transmitted faster through the C fibres than the A delta fibres d. stimulation of the ß receptors in the brain produces analgesia

Description : The following are true about pain: a. in disseminated cancer can be effectively relieved by hypophysectomy b. does not ascend through the dorsal column of the spinal cord c. is transmitted faster ... fibres than the A delta fibres d. stimulation of the ß receptors in the brain produces analgesia

Last Answer : stimulation of the ß receptors in the brain produces analgesia

Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia

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Last Answer : C. Mediates low ceiling respiratory depression

Morphine analgesia differs from that produced by aspirin in the following respect(s): A. It has a higher ceiling B. It covers both perception as well as psychic processing of the pain C. Visceral and ischaemic pain is relieved better than somatic inflammatory pain D. All of the above are correct

Description : Morphine analgesia differs from that produced by aspirin in the following respect(s): A. It has a higher ceiling B. It covers both perception as well as psychic processing of the pain C. Visceral and ischaemic pain is relieved better than somatic inflammatory pain D. All of the above are correct

Last Answer : D. All of the above are correct

Which action of morphine is incompletely reversed by naloxone: A. Analgesia B. Respiratory depression C. Sedation D. Miosis

Description : Which action of morphine is incompletely reversed by naloxone: A. Analgesia B. Respiratory depression C. Sedation D. Miosis

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Low concentration of bupivacaine is preferred for spinal / epidural obstetric analgesia because: A. It has a longer duration of action B. It can produce sensory blockade without paralysing abdominal muscles C. It distributes more in maternal tissues so that less reaches the foetus D. All of the above are correct

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The following statement is true about endogenous opioid peptides: A. They activate only μ opioid recepors B. They do not occur in peripheral tissues C. They mediate stress induced analgesia D. Naloxone fails to antagonise their actio

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A. It is a clonidine congener used in spasticity due to stroke or spinal injury B. It reduces muscle tone by activating GABAB receptors C. It inhibits release of excitatory amino-acids in spinal interneurones D. It reduces muscle spasms without producing weaknes

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Methyldopa lowers BP by: A. Inhibiting dopa decarboxylase in adrenergic nerve endings B. Generating α-methyl noradrenaline in brain which reduces sympathetic tone C. Generating α-methyl noradrenaline which acts as a false transmitter in peripheral adrenergic nerve endings D. Activating vascular dopamine receptors

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General anaesthetics produce immobility in response to painful surgical stimuli by acting primarily at the: A. Motor cortex B. Basal ganglia C. Thalamus D. Spinal cord

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Last Answer : D. Spinal cord

Choose the correct statement(s) about ipratropium bromide: A. It preferentially dilates peripheral bronchioles B. It produces additional bronchodilatation when added to nebulized salbutamol C. As metered dose inhaler it is used for terminating asthma attacks D. Both 'B' and 'C'

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Entacapone differs from tolcapone in the following respect/respects: A. It is shorter acting B. It acts only by inhibiting peripheral metabolism of levodopa C. It is not hepatotoxic D. All of the above are correct

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Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It is a synthetic atropine substitute used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation

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Last Answer : A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms

The following is not true of naltrexone: A. It produces agonistic actions of its own in the absence of morphine B. It is active orally C. It has a long duration of action D. It can reduce craving for alcohol in chronic alcoholics

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The following is true of buprenorphine: A. It is an agonist-antagonist type of opioid analgesic B. Its subjective effects are different from those of morphine C. Naloxone is largely ineffective in reversing its effects D. It produces mydriasis

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Last Answer : C. Naloxone is largely ineffective in reversing its effects

Nalorphine is nearly equipotent analgesic as morphine, but is not used clinically as an analgesic because: A. It causes more marked respiratory depression B. It has higher abuse potential C. It antagonises the action of morphine D. It produces prominent dysphoric effects

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The following is true of pethidine except: A. At equianalgesic doses it causes less respiratory depression than morphine B. It is less constipating than morphine C. It is a poor antitussive D. In overdose it often produces excitatory effect

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Ropinirole differs from bromocriptine in the following respect: A. It does not directly activate dopamine D2 receptors B. It produces milder gastrointestinal side effects C. In early cases of parkinsonism, it is less likely to need levodopa supplementation D. Both 'B' and 'C' are correct

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Last Answer : D. Both 'B' and 'C' are correct

Which action of morphine is incompletely reversed by naloxone ? (a) Analgesia (b) Respiratory depression (c) Sedation (d) Miosis

Description : Which action of morphine is incompletely reversed by naloxone ? (a) Analgesia (b) Respiratory depression (c) Sedation (d) Miosis

Last Answer : Ans: C

Significant tolerance does not develop to the following action of morphine: A. Analgesia B. Euphoria C. Sedation D. Miosis

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Last Answer : D. Miosis

Prostaglandins are chemical substances thought to a) increase sensitivity of pain receptors. Prostaglandins are believed to increase sensitivity to pain receptors by enhancing the pain-provoking effect of bradykinin. b) reduce the perception of pain. Endorphins and enkephalins reduce or inhibit transmission or perception of pain. c) inhibit the transmission of pain. Endorphins and enkephalins reduce or inhibit transmission or perception of pain. d) inhibit the transmission of noxious stimuli. Morphine and other opioid medications inhibit the transmission of noxious stimuli by mimicking enkephalin and endorphin.

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Last Answer : a) increase sensitivity of pain receptors. Prostaglandins are believed to increase sensitivity to pain receptors by enhancing the pain-provoking effect of bradykinin.

Epidural anaesthesia differs from spinal anaesthesia in that: A. Epidural anaesthesia produces less cardiovascular complications B. Headache is more common after epidural anaesthesia C. Blood concentrations of the local anaesthetic are lower after epidural anaesthesia D. Greater separation between sensory and motor blockade can be obtained with epidural anaesthes

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The following antihypertensive drug has been found to suppress certain manifestations of morphine withdrawal syndrome and to block postoperative pain when injected intrathecally: A. Prazosin B. Clonidine C. Reserpine D. Ketanserin

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Indicate the opioid analgesic that is used as transdermal patch for chronic and cancer pain: A. Morphine B. Pentazocine C. Fentanyl D. Tramadol

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Last Answer : The distinctive feature(s) of methadone compared to morphine is/are: A. High oral bioavailability B. High plasma protein and tissue binding C. Delayed and milder withdrawal symptoms in dependent subjects D. All of the above

Morphine is contraindicated in head injury because: A. It does not relieve the pain of head injury B. It can raise intracranial tension C. It can cause constipation D. It is liable to cause addiction

Description : Morphine is contraindicated in head injury because: A. It does not relieve the pain of head injury B. It can raise intracranial tension C. It can cause constipation D. It is liable to cause addiction

Last Answer : B. It can raise intracranial tension

Use of morphine in preanaesthetic medication: A. Is routine except in the presence of contraindications B. Is restricted to patients being anaesthetised with ether C. Should be made only in combination with atropine D. Is restricted mostly to patients in pain preoperativel

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Last Answer : D. Is restricted mostly to patients in pain preoperatively

Select the drug which inhibits cyclooxygenase in the brain but not at peripheral sites of inflammation: A. Nimesulide B. Paracetamol C. Ketorolac D. Mephenamic acid

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Strychnine produces convulsions by: A. Stimulating NMDA receptors B. Facilitating the excitatory transmitter glutamate C. Blocking the inhibitory transmitter GABA D. Blocking the inhibitory transmitter glycine

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Last Answer : D. Blocking the inhibitory transmitter glycine

Though bromocriptine acts directly on dopamine receptors, it is used in parkinsonism only as a supplement to levodopa because: A. It has low efficacy B. It produces marked dyskinesias C. Used alone, its effective doses produce intolerable side effects D. Its therapeutic effect takes long time to develop

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Last Answer : C. Used alone, its effective doses produce intolerable side effect

Which one of the following statements about dextromethorphan is accurate? (a) Activates kappa receptors (b) Analgesia equivalent to pentazocine (c) Highly effective antiemetic (d) Less constipation than codeine (e) Use requires a prescription

Description : Which one of the following statements about dextromethorphan is accurate? (a) Activates kappa receptors (b) Analgesia equivalent to pentazocine (c) Highly effective antiemetic (d) Less constipation than codeine (e) Use requires a prescription

Last Answer : Ans: D

Choose the correct statement about nonopioid analgesics: A. All have antiinflammatory property B. All lack dependence producing liability C. All act exclusively at peripheral pain mechanisms D. All inhibit prostaglandin synthesis

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Last Answer : B. All lack dependence producing liability

Norpethidine produced as a metabolite of pethidine is responsible for the following effect: A. Euphoria B. Excitement C. Analgesia D. Respiratory depression

Description : Norpethidine produced as a metabolite of pethidine is responsible for the following effect: A. Euphoria B. Excitement C. Analgesia D. Respiratory depression

Last Answer : B. Excitement

Intravenous fentanyl is used in balanced anaesthesia to afford: A. Relaxation of chest muscles B. Analgesia C. Unconsciousness D. Suppression of gastric acid secretion

Description : Intravenous fentanyl is used in balanced anaesthesia to afford: A. Relaxation of chest muscles B. Analgesia C. Unconsciousness D. Suppression of gastric acid secretion

Last Answer : B. Analgesia

The anaesthetic action of thiopentone sodium is characterised by: A. Good muscle relaxation B. Poor analgesia C. Sensitization of heart to adrenaline D. No postoperative residual CNS depression

Description : The anaesthetic action of thiopentone sodium is characterised by: A. Good muscle relaxation B. Poor analgesia C. Sensitization of heart to adrenaline D. No postoperative residual CNS depression

Last Answer : B. Poor analgesia

Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

Last Answer : B. It is longer acting

Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

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Last Answer : B. It is longer acting

The site of action of d-tubocurarine is: A. Spinal internuncial neurone B. Motor nerve ending C. Muscle end-plate D. Sodium channels in the muscle fibre

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Fluconazole offers the following advantage(s) over ketoconazole: A. It is longer acting B. Its absorption from stomach is not dependent on gastric acidity C. It produces fewer side effects D. All of the above

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Last Answer : D. All of the above

Ranitidine differs from cimetidine in the following respect: A. It is less potent B. It is shorter acting C. It does not have antiandrogenic action D. It produces more CNS side effect

Description : Ranitidine differs from cimetidine in the following respect: A. It is less potent B. It is shorter acting C. It does not have antiandrogenic action D. It produces more CNS side effect

Last Answer : C. It does not have antiandrogenic action

The following statement is correct about buspirone: A. It interacts with benzodiazepine receptor as an inverse agonist B. It is a rapidly acting anxiolytic, good for panic states C. It produces physical dependence and suppresses barbiturate withdrawal syndrome D. It has anxiolytic but no anticonvulsant or muscle relaxant propert

Description : The following statement is correct about buspirone: A. It interacts with benzodiazepine receptor as an inverse agonist B. It is a rapidly acting anxiolytic, good for panic states C. ... suppresses barbiturate withdrawal syndrome D. It has anxiolytic but no anticonvulsant or muscle relaxant propert

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Methyldopa differs from clonidine in the following respect: A. It is less likely to cause rebound hypertension on sudden discontinuation B. It does not reduce plasma renin activity C. It has a central as well as peripheral site of antihypertensive action D. It does not produce central side effect

Description : Methyldopa differs from clonidine in the following respect: A. It is less likely to cause rebound hypertension on sudden discontinuation B. It does not reduce plasma renin activity C. It has a central as well as peripheral site of antihypertensive action D. It does not produce central side effect

Last Answer : A. It is less likely to cause rebound hypertension on sudden discontinuation

Identify the molecules (A) and (B) shown below and select the right option giving their source and use.(a) (A) Cocaine Erythroxylum Accelerates coca the transport of dopamine (b) (B) Heroin Cannabis Depressant sativa and slows down body functions (c) (B) Cannabi- Atropa Produces noid belladonna hallucinations (d) (A) Morphine Papaver Sedative and somniferum pain killer

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Last Answer : (d) (A) Morphine Papaver Sedative and somniferum pain killer

Morphine dependence is characterized by: A. Marked drug seeking behaviour B. Physical dependence without psychic dependence C. Physical as well as psychic dependence D. Both ‘A’ and ‘C’ are correc

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Last Answer : D. Both ‘A’ and ‘C’ are correc

The greatest threat from morphine poisoning is (a) Renal shutdown (b) Paralysis of spinal cord (c) Respiratory depression (d) Cardiovascular collapse (e) None of the above

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Last Answer : Ans: C

All the following statements about βendorphin are true except µ : (A) It is a polypeptide (B) Its precursor is pro-opio-melanocortin (C) Its receptors are represent in brain (D) Its action is blocked by morphine

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The following is true of clarithromycin except: A. It produces less gastric irritation and pain than erythromycin B. It is the most active macrolide antibiotic against Helicobacter pylori C. It does not interact with terfenadine or cisapride to cause cardiac arrhythmias D. It exhibits dose dependent elimination kinetics

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The following statement is true about misoprostol: A. It relieves peptic ulcer pain, but does not promote ulcer healing B. It heals nonsteroidal antiinflammatory drug induced gastric ulcer not responding to H2 blockers C. It produces fewer side effects than H2 blockers D. It is the most effective drug for preventing ulcer relapse

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2 In a conscious patient of poisoning, use of an emetic is permissible in case the ingested poison is: A. Ferrous sulfate B. Sodium hydroxide C. Kerosine D. Morphine

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