Low concentration of bupivacaine is preferred for spinal / epidural obstetric analgesia because: A. It has a longer duration of action B. It can produce sensory blockade without paralysing abdominal muscles C. It distributes more in maternal tissues so that less reaches the foetus D. All of the above are correct

Low concentration of bupivacaine is preferred for
spinal / epidural obstetric analgesia because:
A. It has a longer duration of action
B. It can produce sensory blockade without
paralysing abdominal muscles
C. It distributes more in maternal tissues so
that less reaches the foetus
D. All of the above are correct
by

1 Answer

Answer :

D. All of the above are correct
by

Related questions

Epidural anaesthesia differs from spinal anaesthesia in that: A. Epidural anaesthesia produces less cardiovascular complications B. Headache is more common after epidural anaesthesia C. Blood concentrations of the local anaesthetic are lower after epidural anaesthesia D. Greater separation between sensory and motor blockade can be obtained with epidural anaesthes

Description : Epidural anaesthesia differs from spinal anaesthesia in that: A. Epidural anaesthesia produces less cardiovascular complications B. Headache is more common after epidural anaesthesia C. Blood ... . Greater separation between sensory and motor blockade can be obtained with epidural anaesthes

Last Answer : D. Greater separation between sensory and motor blockade can be obtained with epidural anaesthesia

Which of the following is not the reason for greater susceptibility of smaller sensory fibres to blockade by local anaesthetics than larger motor fibres: A. Sensory fibres are inherently more sensitive than motor fibres B. More slender fibres have shorter internodal distances C. Small sensory fibres generate higher frequency longer lasting action potential D. Smaller fibres have shorter critical lengths for blockade

Description : Which of the following is not the reason for greater susceptibility of smaller sensory fibres to blockade by local anaesthetics than larger motor fibres: A. Sensory fibres are inherently ... higher frequency longer lasting action potential D. Smaller fibres have shorter critical lengths for blockade

Last Answer : A. Sensory fibres are inherently more sensitive than motor fibres

n which of the following techniques the concentration of the local anaesthetic used is the lowest: A. Infiltration anaesthesia B. Nerve block anaesthesia C. Spinal anaesthesia D. Epidural anaesthesia

Description : n which of the following techniques the concentration of the local anaesthetic used is the lowest: A. Infiltration anaesthesia B. Nerve block anaesthesia C. Spinal anaesthesia D. Epidural anaesthesia

Last Answer : A. Infiltration anaesthesia

Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : A. They have potent antiovulatory action of their own

Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : B. They produce many side effects

Sensitivity of a nerve fibre to blockade by lignocaine depends on: A. Whether the fibre is sensory or motor B. Whether the fibre is myelinated or nonmyelinated C. Internodal distances in the fibre D. Both ‘B’ and ‘C’ are correct

Description : Sensitivity of a nerve fibre to blockade by lignocaine depends on: A. Whether the fibre is sensory or motor B. Whether the fibre is myelinated or nonmyelinated C. Internodal distances in the fibre D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Low molecular weight heparins differ from unfractionated heparin in that: A. They selectively inhibit factor Xa B. They do not significantly prolong clotting time C. They are metabolized slowly and have longer duration of action D. All of the above are correct

Description : Low molecular weight heparins differ from unfractionated heparin in that: A. They selectively inhibit factor Xa B. They do not significantly prolong clotting time C. They are metabolized slowly and have longer duration of action D. All of the above are correct

Last Answer : D. All of the above are correct

In the treatment of parkinsonism, bromocriptine differs from levodopa in the following respects except: A. It does not need conversion to an active metabolite B. It has a longer duration of action C. It activates dopamine D2 receptors, with little/antagonistic action on D1 receptors D. It does not produce behavioral/psychiatric side effect

Description : In the treatment of parkinsonism, bromocriptine differs from levodopa in the following respects except: A. It does not need conversion to an active metabolite B. It has a longer duration of ... with little/antagonistic action on D1 receptors D. It does not produce behavioral/psychiatric side effect

Last Answer : D. It does not produce behavioral/psychiatric side effects

The duration of spinal anaesthesia depends on each of the following except: A. Which local anaesthetic is used B. Concentration of the local anaesthetic used C. Posture of the patient D. Whether adrenaline has been added to the local anaesthetic

Description : The duration of spinal anaesthesia depends on each of the following except: A. Which local anaesthetic is used B. Concentration of the local anaesthetic used C. Posture of the patient D. Whether adrenaline has been added to the local anaesthetic

Last Answer : C. Posture of the patient

Morphine produces analgesia by acting at: A. Peripheral pain receptors B. A spinal site C. Supraspinal sites D. Both spinal and supraspinal sites

Description : Morphine produces analgesia by acting at: A. Peripheral pain receptors B. A spinal site C. Supraspinal sites D. Both spinal and supraspinal sites

Last Answer : D. Both spinal and supraspinal sites

Succinylcholine is the preferred muscle relaxant for tracheal intubation because: A. It produces rapid and complete paralysis of respiratory muscles with quick recovery B. It does not alter heart rate or blood pressure C. It does not cause histamine release D. It does not produce postoperative muscle soreness

Description : Succinylcholine is the preferred muscle relaxant for tracheal intubation because: A. It produces rapid and complete paralysis of respiratory muscles with quick recovery B. It does not alter heart rate or ... C. It does not cause histamine release D. It does not produce postoperative muscle soreness

Last Answer : A. It produces rapid and complete paralysis of respiratory muscles with quick recovery

The following statement is true about endogenous opioid peptides: A. They activate only μ opioid recepors B. They do not occur in peripheral tissues C. They mediate stress induced analgesia D. Naloxone fails to antagonise their actio

Description : The following statement is true about endogenous opioid peptides: A. They activate only μ opioid recepors B. They do not occur in peripheral tissues C. They mediate stress induced analgesia D. Naloxone fails to antagonise their actio

Last Answer : C. They mediate stress induced analgesia

Intravenous fentanyl is used in balanced anaesthesia to afford: A. Relaxation of chest muscles B. Analgesia C. Unconsciousness D. Suppression of gastric acid secretion

Description : Intravenous fentanyl is used in balanced anaesthesia to afford: A. Relaxation of chest muscles B. Analgesia C. Unconsciousness D. Suppression of gastric acid secretion

Last Answer : B. Analgesia

Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia

Description : Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia

Last Answer : C. Mediates low ceiling respiratory depression

Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate

Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate

Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Last Answer : C. It is less liable to cause abrupt first dose hypotension

Advantages of epidural analgesia include: A. Earlier mobilization after surgery. B. Earlier return of bowel function. C. Shorter hospitalizations. D. Decreased stress response to surgery. E. All of the above.

Description : Advantages of epidural analgesia include: A. Earlier mobilization after surgery. B. Earlier return of bowel function. C. Shorter hospitalizations. D. Decreased stress response to surgery. E. All of the above.

Last Answer : Answer: E DISCUSSION: Epidural analgesia include excellent pain relief, decreased sedation with more rapid recovery to presurgical levels of consciousness, earlier mobilization after surgery ... , shorter hospitalizations, and decreased morbidity have all been associated with epidural analgesia

In spinal anaesthesia the segmental level of: A. Sympathetic block is lower than the sensory block B. Sympathetic block is higher than the sensory block C. Motor block is higher than the sensory block D. Sympathetic, motor and sensory block has the same level

Description : In spinal anaesthesia the segmental level of: A. Sympathetic block is lower than the sensory block B. Sympathetic block is higher than the sensory block C. Motor block is higher than the sensory block D. Sympathetic, motor and sensory block has the same level

Last Answer : B. Sympathetic block is higher than the sensory block

The following is correct about antipsychotic drugs except: A. They only control symptoms of schizophrenia without affecting the basic disorder B. Combination of two or more antipsychotic drugs is more efficacious than any single drug C. In treating psychosis high potency drugs are preferred over low potency drugs D. They donot produce dependence

Description : The following is correct about antipsychotic drugs except: A. They only control symptoms of schizophrenia without affecting the basic disorder B. Combination of two or more antipsychotic drugs is ... psychosis high potency drugs are preferred over low potency drugs D. They donot produce dependence

Last Answer : B. Combination of two or more antipsychotic drugs is more efficacious than any single drug

The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case

Description : The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case

Last Answer : D. They are the preferred drugs in advanced cases

Select the opioid antagonist that is preferred for long term opioid blockade therapy of post addicts: A. Nalorphine B. Naloxone C. Naltrexone D. Nalbuphine

Description : Select the opioid antagonist that is preferred for long term opioid blockade therapy of post addicts: A. Nalorphine B. Naloxone C. Naltrexone D. Nalbuphine

Last Answer : C. Naltrexone

Enalapril differs from captopril in the following features except: A. It is dose to dose more potent B. Its oral absorption is not affected by food in stomach C. It acts more rapidly D. It has longer duration of action

Description : Enalapril differs from captopril in the following features except: A. It is dose to dose more potent B. Its oral absorption is not affected by food in stomach C. It acts more rapidly D. It has longer duration of action

Last Answer : D. Lisinopri

'Diffusion hypoxia’ is likely to occur only after use of nitrous oxide because it: A. Is a respiratory depressant B. Has low blood solubility and is used in high concentration C. Is a very potent anaesthetic D. Interferes with diffusion of oxygen into the tissues

Description : 'Diffusion hypoxia’ is likely to occur only after use of nitrous oxide because it: A. Is a respiratory depressant B. Has low blood solubility and is used in high concentration C. Is a very potent anaesthetic D. Interferes with diffusion of oxygen into the tissues

Last Answer : B. Has low blood solubility and is used in high concentration

Compared to erythromycin, azithromycin has: A. Extended antimicrobial spectrum B. Better gastric tolerance C. Longer duration of action D. All of the above

Description : Compared to erythromycin, azithromycin has: A. Extended antimicrobial spectrum B. Better gastric tolerance C. Longer duration of action D. All of the above

Last Answer : D. All of the above

Injection of adrenaline along with a local anaesthetic serves the following purpose: A. Lowers the concentration of the local anaesthetic to produce nerve block B. Prolongs the duration of local anaesthesia C. Increases the anaesthetised area D. Reduces the local toxicity of the local anaesthetic

Description : Injection of adrenaline along with a local anaesthetic serves the following purpose: A. Lowers the concentration of the local anaesthetic to produce nerve block B. Prolongs the duration of local anaesthesia C. Increases the anaesthetised area D. Reduces the local toxicity of the local anaesthetic

Last Answer : B. Prolongs the duration of local anaesthesia

The local anaesthetic having high cardiotoxic and arrhythmogenic potential is: A. Lignocaine B. Procaine C. Bupivacaine D. Ropivacaine

Description : The local anaesthetic having high cardiotoxic and arrhythmogenic potential is: A. Lignocaine B. Procaine C. Bupivacaine D. Ropivacaine

Last Answer : C. Bupivacaine

Signals for parturition originate from (1) Fully developed foetus only (2) Both placenta as well as fully developed foetus (3) Oxytocin released from maternal pituitary (4) Placenta only

Description : Signals for parturition originate from (1) Fully developed foetus only (2) Both placenta as well as fully developed foetus (3) Oxytocin released from maternal pituitary (4) Placenta only

Last Answer : (2) Both placenta as well as fully developed foetus

Which action of morphine is incompletely reversed by naloxone: A. Analgesia B. Respiratory depression C. Sedation D. Miosis

Description : Which action of morphine is incompletely reversed by naloxone: A. Analgesia B. Respiratory depression C. Sedation D. Miosis

Last Answer : C. Sedation

The anaesthetic action of thiopentone sodium is characterised by: A. Good muscle relaxation B. Poor analgesia C. Sensitization of heart to adrenaline D. No postoperative residual CNS depression

Description : The anaesthetic action of thiopentone sodium is characterised by: A. Good muscle relaxation B. Poor analgesia C. Sensitization of heart to adrenaline D. No postoperative residual CNS depression

Last Answer : B. Poor analgesia

The progestin used in combined oral contraceptive pill is a 19-nortestosterone derivative because: A. They have potent antiovulatory action of their own B. They do not produce any metabolic effects C. They produce fewer side effects D. They are longer acting

Description : The progestin used in combined oral contraceptive pill is a 19-nortestosterone derivative because: A. They have potent antiovulatory action of their own B. They do not produce any metabolic effects C. They produce fewer side effects D. They are longer acting

Last Answer : A. They have potent antiovulatory action of their own

Choose the correct statement about tetracyclines: A. Being broad spectrum antibioics they are dependable for empirical treatment of lifethreatening infections B. Currently, they are not the first choice antibiotic for any specific infection C. They reduce stool volume and duration of diarrhoea in cholera D. The are preferred for treatment of anaerobic bacterial infections

Description : Choose the correct statement about tetracyclines: A. Being broad spectrum antibioics they are dependable for empirical treatment of lifethreatening infections B. Currently, they are not the first ... of diarrhoea in cholera D. The are preferred for treatment of anaerobic bacterial infections

Last Answer : C. They reduce stool volume and duration of diarrhoea in cholera

Oxytocin is preferred over ergometrine for augmenting labour because: A. It has brief and titratable action B. It is less likely to cause foetal anoxia C. It is less likely to impede foetal descent D. All of the above

Description : Oxytocin is preferred over ergometrine for augmenting labour because: A. It has brief and titratable action B. It is less likely to cause foetal anoxia C. It is less likely to impede foetal descent D. All of the above

Last Answer : D. All of the above

The preferred route of administration of medication in the most acute care situations is which of the following routes? a) Intravenous The IV route is the preferred parenteral route in most acute care situations because it is much more comfortable for the patient, and peak serum levels and pain relief occur more rapidly and reliably. b) Epidural Epidural administration is used to control postoperative and chronic pain. c) Subcutaneous Subcutaneous administration results in slow absorption of medication. d) Intramuscular Intramuscular administration of medication is absorbed more slowly than intravenously administered medication.

Description : The preferred route of administration of medication in the most acute care situations is which of the following routes? a) Intravenous The IV route is the preferred ... ) Intramuscular Intramuscular administration of medication is absorbed more slowly than intravenously administered medication.

Last Answer : a) Intravenous The IV route is the preferred parenteral route in most acute care situations because it is much more comfortable for the patient, and peak serum levels and pain relief occur more rapidly and reliably.

Neostigmine is beneficial in cobra envenomation because: A. It binds to and inactivates cobra toxin B. It reverses coma due to cobra toxin C. It counteracts the cardio-depressant action of cobra toxin D. It antagonizes the paralysing action of cobra toxin

Description : Neostigmine is beneficial in cobra envenomation because: A. It binds to and inactivates cobra toxin B. It reverses coma due to cobra toxin C. It counteracts the cardio-depressant action of cobra toxin D. It antagonizes the paralysing action of cobra toxin

Last Answer : D. It antagonizes the paralysing action of cobra toxin

Neostigmine is beneficial in cobra envenomation because: A. It binds to and inactivates cobra toxin B. It reverses coma due to cobra toxin C. It counteracts the cardio-depressant action of cobra toxin D. It antagonizes the paralysing action of cobra toxin

Description : Neostigmine is beneficial in cobra envenomation because: A. It binds to and inactivates cobra toxin B. It reverses coma due to cobra toxin C. It counteracts the cardio-depressant action of cobra toxin D. It antagonizes the paralysing action of cobra toxin

Last Answer : D. It antagonizes the paralysing action of cobra toxin

Aspirin produces analgesia by: A. Preventing sensitization of peripheral pain receptors B. Affecting gating of pain impulses at spinal level C. Raising pain threshold at subcortical level D. Both ‘A’ and ‘C’ are correct

Description : Aspirin produces analgesia by: A. Preventing sensitization of peripheral pain receptors B. Affecting gating of pain impulses at spinal level C. Raising pain threshold at subcortical level D. Both ‘A’ and ‘C’ are correct

Last Answer : D. Both ‘A’ and ‘C’ are correct

Anthelmintic action of piperazine is due to: A. Interference with ATP generation in the worm B. Blockade of glucose uptake by the worm C. Hyperpolarization of nematode muscle by GABA agonistic action D. Depolarization of nematode muscle by activating nicotinic receptors

Description : Anthelmintic action of piperazine is due to: A. Interference with ATP generation in the worm B. Blockade of glucose uptake by the worm C. Hyperpolarization of nematode muscle by GABA agonistic action D. Depolarization of nematode muscle by activating nicotinic receptors

Last Answer : C. Hyperpolarization of nematode muscle by GABA agonistic action

The principal action common to all class I antiarrhythmic drugs is: A. Na+ channel blockade B. K+ channel opening C. Depression of impulse conduction D. Prolongation of effective refractory period

Description : The principal action common to all class I antiarrhythmic drugs is: A. Na+ channel blockade B. K+ channel opening C. Depression of impulse conduction D. Prolongation of effective refractory period

Last Answer : A. Na+ channel blockade

Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes little myocardial depression and hypotension C. It has broad spectrum antiarrhythmic efficacy in atrial as well as ventricular arrhythmias D. Both ‘A’ and ‘B’ are correct

Description : Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes ... atrial as well as ventricular arrhythmias D. Both A' and B' are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

Did you know the cortisone used in the spinal epidural is not approved by the FDA for disc problems? Has it helped your back pain?

Description : Did you know the cortisone used in the spinal epidural is not approved by the FDA for disc problems? Has it helped your back pain?

Last Answer : answer:I know two people who have had this sort of thing done. One had significant relief, the other had a very negative experience. Drugs are administered every day off label, which basically means not ... I have no opinion about whether she should try it, only information about drugs and the FDA.

Spinal and epidural anesthesia?

Description : Spinal and epidural anesthesia?

Last Answer : DefinitionSpinal and epidural anesthesia are medicines that numb parts of your body to block pain. They are given through shots in or around the spine. You will stay awake during both of these types of ... just outside of the sac of fluid around your spinal cord. This called the epidural space.The m

In a lower segment caesarean section, which of the following techniques of anesthesia is desirable A. Spinal anesthesia B. Caudal anesthesia C. Combined Spinal Epidural D. General anesthesia

Description : In a lower segment caesarean section, which of the following techniques of anesthesia is desirable A. Spinal anesthesia B. Caudal anesthesia C. Combined Spinal Epidural D. General anesthesia

Last Answer : Ans: C

Morphine analgesia differs from that produced by aspirin in the following respect(s): A. It has a higher ceiling B. It covers both perception as well as psychic processing of the pain C. Visceral and ischaemic pain is relieved better than somatic inflammatory pain D. All of the above are correct

Description : Morphine analgesia differs from that produced by aspirin in the following respect(s): A. It has a higher ceiling B. It covers both perception as well as psychic processing of the pain C. Visceral and ischaemic pain is relieved better than somatic inflammatory pain D. All of the above are correct

Last Answer : D. All of the above are correct

Chlorpropamide is not a preferred sulfonylurea because: A. Hypoglycaemic reaction is more common with it B. Incidence of alcohol intolerance reaction is higher with it C. It can produce cholestatic jaundice D. All of the above

Description : Chlorpropamide is not a preferred sulfonylurea because: A. Hypoglycaemic reaction is more common with it B. Incidence of alcohol intolerance reaction is higher with it C. It can produce cholestatic jaundice D. All of the above

Last Answer : D. All of the above

A resting nerve is relatively resistant to blockade by lignocaine compared to one which is repeatedly stimulated because: A. Lignocaine penetrates resting nerve membrane poorly B. Lignocaine binds more avidly to the inactivated Na+ channel C. Nerve impulse promotes ionization of lignocaine D. Nodes of Ranvier are inaccessible in the resting state

Description : A resting nerve is relatively resistant to blockade by lignocaine compared to one which is repeatedly stimulated because: A. Lignocaine penetrates resting nerve membrane poorly B. Lignocaine binds ... promotes ionization of lignocaine D. Nodes of Ranvier are inaccessible in the resting state

Last Answer : B. Lignocaine binds more avidly to the inactivated Na+ chan

Tolerance does not develop to the vasodilator action of sodium nitroprusside while it develops to glyceryl trinitrate because: A. Intact sod. nitroprusside molecule acts like nitric oxide B. Enzymes which generate nitric oxide from nitroprusside are different C. Sod. nitroprusside has a long duration of action D. Sod. nitroprusside has additional K+ channel opening action

Description : Tolerance does not develop to the vasodilator action of sodium nitroprusside while it develops to glyceryl trinitrate because: A. Intact sod. nitroprusside molecule acts like nitric oxide B. Enzymes which ... a long duration of action D. Sod. nitroprusside has additional K+ channel opening action

Last Answer : B. Enzymes which generate nitric oxide from nitroprusside are different

Use of adenosine for terminating an episode of paroxysmal supraventricular tachycardia has the following advantages except: A. It does not produce any side effect B. It can be given to patients with low blood pressure C. Its action lasts less than 1 min after bolus intravenous injection D. It is effective in patients not responding to verapamil

Description : Use of adenosine for terminating an episode of paroxysmal supraventricular tachycardia has the following advantages except: A. It does not produce any side effect B. It can be given to patients ... 1 min after bolus intravenous injection D. It is effective in patients not responding to verapamil

Last Answer : A. It does not produce any side effect

Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH

Description : Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH

Last Answer : A. They do not cross the blood-brain barrier