Description : Which of the following is an agonist-antagonist type of opioid analgesic: A. Pethidine B. Pentazocine C. Fentanyl D. Buprenorphine
Last Answer : B. Pentazocine
Description : The following opioid is more potent than morphine: A. Pethidine B. Fentanyl C. Dextropropoxyphene D. Tramadol
Last Answer : B. Fentanyl
Description : Which of the following is an agonistantagonist type of opioid analgesic (a) Pethidine (b) Pentazocine (c) Fentanyl (d) Buprenorphine
Last Answer : Ans: B
Description : Select the opioid analgesic which acts primarily through κ (kappa) opioid receptor: A. Pentazocine B. Methadone C. Buprenorphine D. Pethidine
Last Answer : A. Pentazocine
Description : Select the analgesic which acts through opioid as well as additional spinal monoaminergic mechanisms: A. Tramadol B. Ethoheptazine C. Dextropropoxyphene D. Alfentanil
Last Answer : A. Tramado
Description : Pentazocine differs from morphine in that: A. It is inactive by the oral route B. It does not produce physical dependence C. It has a lower ceiling of analgesic effect D. Its action is not blocked by naloxone
Last Answer : C. It has a lower ceiling of analgesic effec
Description : The following is true of buprenorphine: A. It is an agonist-antagonist type of opioid analgesic B. Its subjective effects are different from those of morphine C. Naloxone is largely ineffective in reversing its effects D. It produces mydriasis
Last Answer : C. Naloxone is largely ineffective in reversing its effects
Description : Which of the following narcotics has the longest duration of effect? (a) Methadone (b) Controlled-release morphine (c) Levorphanol (d) Transdermal fentanyl (e) Dihydromorphone
Last Answer : Ans: D
Description : Which of the following opioids is more potent than morphine ? (a) Pethidine (b) Fentanyl (c) Dextropropoxyphene (d) Tramadol
Description : Fentanyl (Sublimaze) is categorized as which type of intravenous anesthetic agent? a) Neuroleptanalgesic Fentanyl is 75-100 times more potent than morphine and has about 25% of the duration ... morphine and meperidine hydrochloride (Demerol). d) Dissociative agent Ketamine is a dissociative agent.
Last Answer : a) Neuroleptanalgesic Fentanyl is 75-100 times more potent than morphine and has about 25% of the duration of morphine (IV).
Description : Pentazocine differs from morphine in that (a) It is inactive by the oral route (b) It does not produce physical dependence (c) It has a lower ceiling of analgesic effect (d) Its action is not blocked by naloxone
Last Answer : Ans: C
Description : Lower dose of naloxone is required to: A. Antagonise the actions of nalorphine B. Antagonise the actions of pentazocine C. Precipitate withdrawal in mildly morphine dependent subjects D. Precipitate withdrawal in highly morphine dependent subjects
Last Answer : D. Precipitate withdrawal in highly morphine dependent subjects
Description : Choose the correct statement about pentazocine: A. It causes bradycardia and fall in blood pressure B. Its subjective effects are pleasurable at low doses but turn unpleasant at high doses C. It induces vomiting frequently D. It substitutes for morphine in dependent subjects
Last Answer : B. Its subjective effects are pleasurable at low doses but turn unpleasant at high doses
Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition: A. Acute gout B. Burn C. Toothache D. Neuralgi
Last Answer : B. Burn
Description : The following opioid analgesic is similar to codeine in pharmacological profile but is less constipating: A. Methadone B. Buprenorphine C. Butorphanol D. Dextropropoxyphene
Last Answer : D. Dextropropoxyphene
Description : Apraclonidine is a clonidine congener which is used: A. To suppress opioid withdrawal syndrome B. To suppress menopausal syndrome C. As Analgesic D. To reduce intraocular tension
Last Answer : D. To reduce intraocular tension
Description : Choose the correct statement about nefopam: A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B. It is an orally active opioid analgesic C. It is an analgesic with potent antiinflammatory activity D. It is a preferential COX-2 inhibitor
Last Answer : A. It is a nonopioid analgesic which does not inhibit prostaglandin synthesis
Description : Morphine has high affinity for the following opioid receptor(s): A. μ (Mu) B. κ (Kappa) C. δ (Delta) D. All of the above
Last Answer : A. μ (Mu
Description : Fentanyl transdermal patches have been used postoperatively to provide transdermal analgesia. The most dangerous adverse effect of this mode of administration is (a) Cutaneous reactions (b) Diarrhea (c) Hypertension (d) Relaxation of skeletal muscle (e) Respiratory depression
Last Answer : Ans: E
Description : Nalorphine is nearly equipotent analgesic as morphine, but is not used clinically as an analgesic because: A. It causes more marked respiratory depression B. It has higher abuse potential C. It antagonises the action of morphine D. It produces prominent dysphoric effects
Last Answer : D. It produces prominent dysphoric effects
Description : Choose the correct statement about codeine: A. It has a lower oral: parenteral activity ratio than morphine B. It is devoid of abuse liability C. It is a weaker analgesic than morphine D. It is a more potent antitussive than morphine
Last Answer : C. It is a weaker analgesic than morphine
Description : The following is not true of morphine: A. Its 2-glucuronide metabolite is an active analgesic B. Its active metabolite penetrates blood-brain barrier better than morphine C. Its oral: parenteral activity ratio is 1:4 D. It undergoes enterohepatic cycling
Last Answer : B. Its active metabolite penetrates blood-brain barrier better than morphine
Description : Prostaglandins are chemical substances thought to a) increase sensitivity of pain receptors. Prostaglandins are believed to increase sensitivity to pain receptors by enhancing the pain-provoking ... opioid medications inhibit the transmission of noxious stimuli by mimicking enkephalin and endorphin.
Last Answer : a) increase sensitivity of pain receptors. Prostaglandins are believed to increase sensitivity to pain receptors by enhancing the pain-provoking effect of bradykinin.
Description : The following is not true of naltrexone: A. It produces agonistic actions of its own in the absence of morphine B. It is active orally C. It has a long duration of action D. It can reduce craving for alcohol in chronic alcoholics
Last Answer : A. It produces agonistic actions of its own in the absence of morphin
Description : Ran out of medical tape. How can I secure this transdermal nicotine patch in place?
Last Answer : You could lightly wrap gauze around. A rubber band (or two) if it's on the inside of the wrist. Place it on the inside of your waistline so the elastic of your underwear can help hold it in place for ... was my upper arm, and even then only for about two hours. The gum works a lot better for me.
Description : Lower dose of naloxone is required to (a) Antagonise the actions of nalorphine (b) Antagonise the actions of pentazocine (c) Precipitate withdrawal in mildly morphine dependent subjects (d) Precipitate withdrawal in highly morphine dependent subjects
Description : Select the analgesic which acts through opioids as well as additional spinal monoaminergic mechanisms. (a) Tramadol (b) Ethoheptazine (c) Dextropropoxyphene (d) Alfentanil
Last Answer : Ans: A
Description : Which analgesic-antiinflammatory drug is more appropriate in musculo-skeletal disorder where pain is more prominent than inflammation: A. Ibuprofen B. Piroxicam C. Indomethacin D. Nimesulide
Last Answer : A. Ibuprofen
Description : Indicate the drug(s) that is/are used to treat chronic hepatitis B: A. Human interferon α B. Lamivudine C. Amantadine D. Both 'A' and 'B'
Last Answer : D. Both 'A' and 'B'
Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition. (a) Acute gout (b) Burn (c) Toothache (d) Neuralgia
Description : The following opioids are κ (kappa) receptor analgesics except: A. Buprenorphine B. Butorphanol C. Nalbuphine D. Pentazocine
Last Answer : A. Buprenorphine
Description : Nitrate tolerance is least likely to develop with the use of: A. Sustained release oral glyceryl trinitrate B. Sublingual glyceryl trinitrate C. Transdermal glyceryl trinitrate D. Oral pentaerythritol tetranitrate
Last Answer : B. Sublingual glyceryl trinitrate
Description : Transdermal estradiol differs from oral estrogen therapy in that it: A. Causes less induction of hepatic synthesis of clotting factors B. Does not inhibit FSH secretion C. Does not affect vaginal cytology D. All of the above are correct
Last Answer : A. Causes less induction of hepatic synthesis of clotting factors
Description : For the treatment of hypogonadism and impotence, testosterone/dihydrotestosterone can be administered by the following route/routes: A. Oral B. Intramuscular C. Transdermal D. Both 'B' and 'C
Last Answer : D. Both 'B' and 'C'
Description : The following antihypertensive drug has been found to suppress certain manifestations of morphine withdrawal syndrome and to block postoperative pain when injected intrathecally: A. Prazosin B. Clonidine C. Reserpine D. Ketanserin
Last Answer : B. Clonidine
Description : Morphine is contraindicated in head injury because: A. It does not relieve the pain of head injury B. It can raise intracranial tension C. It can cause constipation D. It is liable to cause addiction
Last Answer : B. It can raise intracranial tension
Description : Morphine produces analgesia by acting at: A. Peripheral pain receptors B. A spinal site C. Supraspinal sites D. Both spinal and supraspinal sites
Last Answer : D. Both spinal and supraspinal sites
Description : Morphine analgesia differs from that produced by aspirin in the following respect(s): A. It has a higher ceiling B. It covers both perception as well as psychic processing of the pain C. Visceral and ischaemic pain is relieved better than somatic inflammatory pain D. All of the above are correct
Last Answer : D. All of the above are correct
Description : Use of morphine in preanaesthetic medication: A. Is routine except in the presence of contraindications B. Is restricted to patients being anaesthetised with ether C. Should be made only in combination with atropine D. Is restricted mostly to patients in pain preoperativel
Last Answer : D. Is restricted mostly to patients in pain preoperatively
Description : Intravenous fentanyl is used in balanced anaesthesia to afford: A. Relaxation of chest muscles B. Analgesia C. Unconsciousness D. Suppression of gastric acid secretion
Last Answer : B. Analgesia
Description : Select the anaesthetic that increases cardiac output and blood pressure: A. Halothane B. Fentanyl C. Ketamine D. Diazepam
Last Answer : C. Ketamine
Description : The drug/drugs used mainly for induction of general anaesthesia is/are: A. Thiopentone sodium B. Fentanyl + droperidol C. Ketamine D. All of the above
Last Answer : A. Thiopentone sodium
Description : Morphine has high affinity for the following opioid receptor(s). (a) µ (Mu) (b) k (Kappa) (c) d (Delta) (d) All of the above
Description : Opioid analgesics are either contraindicated or must be used with extreme caution in several clinical situations. For morphine, such situations do not include (a) Aqueous diffusion (b) Aqueous hydrolysis (c) Lipid diffusion (d) Pinocytosis or endocytosis (e) Special carrier transport
Description : A drug that decreases blood pressure and has analgesic and spasmolytic effects when given intrathecally is (a) Atenolol (b) Clonidine (c) Morphine (d) Nitroprusside (e) Prazosin
Description : Out of morphine, N-Acetyl-para-aminophenol, Diazepam and tetrahydrocatenol, which can be used as analgesic without causing addiction ?
Last Answer : Ans. N-Acetyl-para-aminophenol.
Description : Which one of the following is correct match? (a) Reserpine – tranquilliser (b) Cocaine – opiatic narcotic (c) Morphine – hallucinogenic (d) Bhang – analgesic
Last Answer : (a) Reserpine – tranquilliser
Description : The following is true of loperamide except: A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action B. It acts on the opioid receptors in the gut C. It increases ... of the intestines D. It inhibits intestinal secretion by binding to calmodulin in the mucosal cells
Last Answer : A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action
Description : 4 Choose the correct statement about the role of opioid antimotility drugs in the management of diarrhoeas: A. They are used to control diarrhoea irrespective of its etiology B. They should ... antimicrobial therapy of diarrhoea D. They are the drugs of choice in irritable bowel syndrome diarrhoea
Last Answer : B. They should be used only as a short-term measure after ensuring that enteroinvasive organisms are not involved