Description : Which action of morphine is incompletely reversed by naloxone ? (a) Analgesia (b) Respiratory depression (c) Sedation (d) Miosis
Last Answer : Ans: C
Description : Morphine produces analgesia by acting at (a) Peripheral pain receptors (b) A spinal site (c) Suspraspinal sites (d) Both (b) and (c)
Last Answer : Ans: B
Description : In a comatose patient suspected of poisoning, which of the following findings would be against the drug being morphine (a) Selegiline (b) Chlorgiline (c) Moclobemide (d) Tranylcypromine
Last Answer : Ans: A
Description : Which of the following categories of medications may result in seizure activity if withdrawn suddenly? a) Tranquilizers Abrupt withdrawal of tranquilizers may result in anxiety, tension, ... may cause excessive respiratory depression during anesthesia due to an associated electrolyte imbalance.
Last Answer : a) Tranquilizers Abrupt withdrawal of tranquilizers may result in anxiety, tension, and even seizures if withdrawn suddenly.
Description : Fentanyl transdermal patches have been used postoperatively to provide transdermal analgesia. The most dangerous adverse effect of this mode of administration is (a) Cutaneous reactions (b) Diarrhea (c) Hypertension (d) Relaxation of skeletal muscle (e) Respiratory depression
Last Answer : Ans: E
Description : In a comatose patient suspected of poisoning, which of the following findings would be against the drug being morphine: A. Mydriasis B. Marked respiratory depression C. Cyanosis D. Fall in blood pressure
Last Answer : A. Mydriasis
Description : A very common side effect of morphine is (a) Allergic response (b) Blood dyscrasias (c) Constipation (d) Liver damage (e) Visceral pain
Description : The emetic action of morphine is due to (a) Irritation of gastrointestinal tract (b) Stimulation of cerebral cortex (c) Stimulation of medullary vomiting center (d) Stimulation of emetic chemoreceptor trigger zone (e) None of the above
Last Answer : Ans: D
Description : Which of the following narcotics has the longest duration of effect? (a) Methadone (b) Controlled-release morphine (c) Levorphanol (d) Transdermal fentanyl (e) Dihydromorphone
Description : A drug that decreases blood pressure and has analgesic and spasmolytic effects when given intrathecally is (a) Atenolol (b) Clonidine (c) Morphine (d) Nitroprusside (e) Prazosin
Description : Opioid analgesics are either contraindicated or must be used with extreme caution in several clinical situations. For morphine, such situations do not include (a) Aqueous diffusion (b) Aqueous hydrolysis (c) Lipid diffusion (d) Pinocytosis or endocytosis (e) Special carrier transport
Description : Lower dose of naloxone is required to (a) Antagonise the actions of nalorphine (b) Antagonise the actions of pentazocine (c) Precipitate withdrawal in mildly morphine dependent subjects (d) Precipitate withdrawal in highly morphine dependent subjects
Description : Pentazocine differs from morphine in that (a) It is inactive by the oral route (b) It does not produce physical dependence (c) It has a lower ceiling of analgesic effect (d) Its action is not blocked by naloxone
Description : Morphine has high affinity for the following opioid receptor(s). (a) µ (Mu) (b) k (Kappa) (c) d (Delta) (d) All of the above
Description : Which of the following opioids is more potent than morphine ? (a) Pethidine (b) Fentanyl (c) Dextropropoxyphene (d) Tramadol
Description : Morphine is contraindicated in head injury because (a) It does not relieve the pain of head injury (b) It can raise intracranial tension (c) It can cause constipation (d) It is liable to cause addiction
Description : Morphine dependence is characterized by (a) Marked drug seeking behavior (b) Physical dependence without psychic dependence (c) Physical as well as psychic dependence (d) Both (a) and (c)
Description : Instead of depressing, morphine stimulates (a) Vasomotor centre (b) Edinger westphal nucleus (c) Temperature regulating centre (d) Cough centre
Description : In man sedation caused by morphine is characterized by (a) Initial excitement (b) Little or no motor incoordination (c) Rise in seizure threshold (d) All of the above
Description : Aspirin produces analgesia by (a) Preventing sensitization of peripheral pain receptors (b) Affecting gating of pain impulses at spinal level (c) Raising pain threshold at subcortical level (d) Both (a) and (b)
Description : Select the analgesic which acts through opioids as well as additional spinal monoaminergic mechanisms. (a) Tramadol (b) Ethoheptazine (c) Dextropropoxyphene (d) Alfentanil
Description : Potential adverse effects associated with aspirin include all of the following except (a) Gastrointestinal ulceration (b) Renal dysfunction (c) Enhanced methotrexate toxicity (d) Cardiac arrhythmias (e) Hypersensitivity asthma
Description : The main advantage of ketorolac over aspirin is that ketorolac (a) Can be combined more safely with an opioid such as codeine (b) Can be obtained as an over-the-counter agent (c) Does not ... (e) Is less likely to cause acute renal failure in patients with some preexisting degree of renal impairment
Description : What advancements have been made in using spinal cord surgery to treat paralysis in the last 5 years?
Last Answer : In the past 5 years there has been many different advancements in the use of spinal cord surgery. This treatment is designed to help reform broken pieces of the spine.
Description : Corticosteroid therapy is practically mandatory in the following condition. (a) Septic shock (b) Renal transplant (c) Rheumatoid arthritis (d) Ulcerative colitis
Description : The toxicity spectrum of aspirin does not include (a) Increased risk of encephalopathy in children with viral infections (b) Increased risk of peptic ulcers (c) Hyperprothrombinemia (d) Metabolic acidosis (e) Respiratory alkalosis
Description : Which one of the following effects does not occur in salicylate intoxication ? (a) Hyperventilation (b) Hypothemia (c) Metabolic acidosis (d) Respiratory alkalosis (e) Tinnitus
Description : Morphine poisoning causes (A) Metabolic acidosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Respiratory alkalosis
Last Answer : Answer : B
Description : The respiratory centres, which control inspiration and expiration, are located in (a) diencephalon (b) medulla oblongata (c) cerebellum (d) spinal cord.
Last Answer : b) medulla oblongata
Description : The nurse anticipates that the immunosuppressed patient is at greatest risk for which type of shock? a) Septic Septic shock is associated with immunosuppression, extremes of age, ... disease of the heart. d) Anaphylactic Anaphylactic shock is associated with hypersensitivity reactions.
Last Answer : a) Septic Septic shock is associated with immunosuppression, extremes of age, malnourishment, chronic illness, and invasive procedures.
Description : Respiratory acidosis occurs in (A) Any disease which impairs respiration like emphysema (B) Renal disease (C) Poisoning by an acid (D) Pyloric stenosis
Last Answer : Answer : A
Description : Regarding morphine, all are true Except A. Respiratory depression ... effect B. Can be IV subcutaneously, rectally and epidurally C. Can cause nausea and vomiting D. Less effective against pain of myocardial ischemia
Description : Which action of morphine is incompletely reversed by naloxone: A. Analgesia B. Respiratory depression C. Sedation D. Miosis
Last Answer : C. Sedation
Description : Morphine affords symptomatic relief of dyspnoea in acute left ventricular failure by the following mechanisms except: A. Bronchodilatation B. Depression of respiratory centre C. Reduction in cardiac preload D. Shift of blood from pulmonary to systemic circuit
Last Answer : A. Bronchodilatation
Description : Respiratory alkalosis occurs in (A) Hysterical hyperventilation (B) Depression of respiratory centre (C) Renal diseases (D) Loss of intestinal fluids
Description : Which of the following durgs is a monamine oxidase inhibitor, but is used to treat hypertension? (a) Tranylcypromine (Parnate) (b) Reserpine (c) Propranolol (Inderal) (d) Pargyline (Eutonyl) (e) Imipramine (Tofranil)
Description : Codeine acts as a cough sedative by (a) Producing mild nausea (b) Depressing bronchiolar secretions (c) Depressing pulmonary action (d) Depressing cough center (e) Paralyzing sensory nerves of bronchi
Description : Which type of patient is most likely to hypersensitive to aspirin? (a) Intrinsic asthamatic (b) Extrinsic asthamatic (c) Chronic bronchitic (d) Patient with viral injection (e) Both (c) and (d)
Description : Colchicine is used mainly to treat (a) Gout (b) Arthiritis (c) Diabetes (d) Carcinomas (e) High blood pressure
Description : All of the following facts are true about non-steroidal anti-inflammatory drugs (NSAIDs) except (a) They are antipyretic (b) There is a celling effect to their analgesia (c) They can cause tolerance (d) They do not cause dependence (e) They are anti-inflammatory
Description : All of the following statements concerning an acute gouty arthritis attack are correct except (a) The diagonosis of gout is assured by a good therapeutic response to colchicines because no ... attack usually involves only one joint, most frequently the big toe (first metatarsophalangeal joint)
Description : Which of the following statements best describes the usual course of rheumatoid arthritis? (a) It is an acute exacerbation of joint pain treated with short-term anti-inflammatory therapy (b) It is ... characterized by a marked loss of calcium from the bones and a resultant thinning of the bones
Description : All of the following medications should not be used routinely in pregnant patients during the third trimester except (a) Acetaminophen (b) Nonsteroidal anti-inflammatory drugs (c) Warfarin (d) Lithium (e) Aspirin
Description : A 65-year-old is interested in taking ginkgo. Which of the following statements is correct regarding ginkgo? (a) Ginkgo is contraindicated in diabetes and pregnancy (b) There is a ... drug-herb interaction between ginkgo and phenelzine (e) Ginkgo is contraindicated in patients with gallstone pain
Description : A FDA – approved ingredient for protection against painful sensitivity of the teeth due to cold, heat, acids, sweets or contact is (a) Dicalcium phosphate (b) Sodium lauryl sulfate (c) 5% potassium nitrate (d) Zinc chloride (e) Calcium carbonate
Description : The termination of heparin activity by protamine sulfate is due to (a) A chelating action (b) The inhibition of gastrointestinal absorption of heparin (c) The displacement of heparin-plasma protein binding (d) An acid-base interaction (e) The prothrombin-like activity of protamine
Description : In addition to their ability to decrease inflammatory prostaglandin synthesis, some non-steroidal anti-inflammatory drugs (NSAIDs) may owe part of their effects to their ability to (a) Inhibit leukocyte migration (b ... (c) Stabilize lysosmal membranes (d) All of the above (e) None of the above
Description : Which of the following medications would represent arthritis therapy that is least likely to cause gastric ulceration? (a) Aspirin (b) Acetaminophen (c) Piroxicam (d) Meclofenamate (e) Rofecoxib
Description : Patients taking chronic doses of nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) should periodically be screened for which of the following toxicities? (a) Nephrotoxicity (b) Peripheral neuropathy (c) Cardiotoxicity (d) All of the above (e) None of the above
Description : Acute or chronic colchicine toxicity may be identified by which of the following signs/symptoms? (a) Alopecia (b) Blood dyscrasias (c) Severe gastrointestinal upset (d) All of the above (e) None of the above