answer:No, there’s not. In fact, because of the versatility of a regular tablet over a Nook-brand tablet, there are some pretty good arguments for going with the tablet. The only things that might sway me, if I had to make the choice, would be: 1) weight. How much does the Nook tablet weigh versus the tablet of your choice? You’ll be holding it and carrying it around. Depending on your arm strength, this might make a difference. 2) cost. If the Nook tablet is seriously significantly less expensive than the corresponding tablet, that might make a difference. I personally got rid of my Nook device (not a nook tablet) and use the app on my tablet 100% of the time.