The blood - brain barrier: a. is permeable to bilirubin at birth b. is formed by the tight junctions between endothlial cells and the end feet processes of astrocytes c. is permeable to glucose d. all above

The blood - brain barrier:
a. is permeable to bilirubin at birth
b. is formed by the tight junctions between endothlial cells and the end feet processes of astrocytes
c. is permeable to glucose
d. all above
by

1 Answer

Answer :

all above
by

Related questions

The blood - brain barrier: a. is permeable to bilirubin at birth b. is formed by the tight junctions between endothlial cells and the end feet processes of astrocytes c. is permeable to glucose d. all above

Description : The blood - brain barrier: a. is permeable to bilirubin at birth b. is formed by the tight junctions between endothlial cells and the end feet processes of astrocytes c. is permeable to glucose d. all above

Last Answer : all above

The following are true about blood-brain barrier: a. it is permeable at birth b. it involves tight junction between endothelial cells and end feet processes of astrocytes c. it is absent in the posterior pituitary d. all above

Description : The following are true about blood-brain barrier: a. it is permeable at birth b. it involves tight junction between endothelial cells and end feet processes of astrocytes c. it is absent in the posterior pituitary d. all above

Last Answer : all above

The blood-brain-barrier: a. contains the foot processes of astrocytes b. contains endothelial cells with tight junction c. allows transport in one direction only ie from the vascular system into the brain d. does not allow diffusion of water

Description : The blood-brain-barrier: a. contains the foot processes of astrocytes b. contains endothelial cells with tight junction c. allows transport in one direction only ie from the vascular system into the brain d. does not allow diffusion of water

Last Answer : does not allow diffusion of water

Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage of lipid soluble drugs into the brain C. It limits entry of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Description : Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage ... of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Last Answer : D. It regulates passage of substances from brain into blood

6 The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Description : 6 The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Last Answer : D. All of the above

Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage of lipid soluble drugs into the brain C. It limits entry of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Description : Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage ... of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Last Answer : D. It regulates passage of substances from brain into blood

The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Description : The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Last Answer : D. All of the above

Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage of lipid soluble drugs into the brain C. It limits entry of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Description : Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage ... of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Last Answer : D. It regulates passage of substances from brain into blood

The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Description : The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Last Answer : D. All of the above

With regard to the blood retina barrier: a. the outer blood retina is formed by the retinal pigment epithelium cells and their junctions b. the blood retina barrier is typically defective in the immediate perpapillary region c. the retinal vascular endothelial cells can actively transport fluid and anions from the extracellular space of the retina into the circulation d. all above

Description : With regard to the blood retina barrier: a. the outer blood retina is formed by the retinal pigment epithelium cells and their junctions b. the blood retina barrier is typically defective in the ... fluid and anions from the extracellular space of the retina into the circulation d. all above

Last Answer : all above

Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH

Description : Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH

Last Answer : A. They do not cross the blood-brain barrier

Which of the following statement(s) is/are correct concerning cell junctions? a. The major occluding junction is the tight junction or zonula occludens b. Tight junctions are usually located near the basal pole of the cell c. Desmosomes are button-like points of attachment which serve to weld together adjacent cells d. Gap junctions are a type of cell junction specialized for cell communication

Description : Which of the following statement(s) is/are correct concerning cell junctions? a. The major occluding junction is the tight junction or zonula occludens b. Tight junctions are usually located near ... adjacent cells d. Gap junctions are a type of cell junction specialized for cell communication

Last Answer : Answer: a, c, d Cell junctions are classified as occluding, anchoring, and communicating. The major occluding junction is the tight junction or zonula occludens which connects ... gap junction which is specialized for communication. This junction mediates both electrical and chemical coupling

At low blood glucose concentration, brain but not liver will take up glucose. It is due to the (A) Low Km of hexokinase (B) Low Km of glucokinase (C) Specificity of glucokinase (D) Blood brain barrier

Description : At low blood glucose concentration, brain but not liver will take up glucose. It is due to the (A) Low Km of hexokinase (B) Low Km of glucokinase (C) Specificity of glucokinase (D) Blood brain barrier

Last Answer : Answer : A

Read the following (A - D) stetements :- (A) Tight junctions help to stop substances from leaking across a tissue (B) Adhering junctions perform cemen

Description : Read the following (A - D) stetements :- (A) Tight junctions help to stop substances from leaking across a tissue (B) Adhering junctions perform cemen

Last Answer : Read the following (A - D) stetements :- (A) Tight junctions help to stop substances from leaking across a ... correct A. Four B. Three C. Two D. One

Cell junctions called tight , adhering and gap junctions are found in

Description : Cell junctions called tight , adhering and gap junctions are found in

Last Answer : Cell junctions called tight , adhering and gap junctions are found in A. Neural tissue B. Muscular tissue C. Connective tissue D. Epithelium tissue

The cell junctions called tight, adhering and gap junctions are found in (a) connective tissue (b) epithelial tissue (c) neural tissue (d) muscular tissue

Description : The cell junctions called tight, adhering and gap junctions are found in (a) connective tissue (b) epithelial tissue (c) neural tissue (d) muscular tissue

Last Answer : (b) epithelial tissue

Which type of jaundice in adults is the result of increased destruction of red blood cells? a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot excrete the bilirubin as quickly as it is formed.

Description : Which type of jaundice in adults is the result of increased destruction of red blood cells? a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot ... is the result of liver disease. d) Non-obstructive Non-obstructive jaundice occurs with hepatitis.

Last Answer : a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot excrete the bilirubin as quickly as it is formed.

The following are true about tight junction: a. it forms a barrier to water b. it is found in the blood-aqueous barrier of the ciliary body c. it is found in the blood-retinal barrier at the apex of the retinal pigment epithelium d. all above

Description : The following are true about tight junction: a. it forms a barrier to water b. it is found in the blood-aqueous barrier of the ciliary body c. it is found in the blood-retinal barrier at the apex of the retinal pigment epithelium d. all above

Last Answer : all above

Consider the following statements regarding the formation of P-N junctions: 1. Holes diffuse across the junction from P-side to N—side 2. The depletion layer is wiped out. 3. There is continuous flow of current across the junction 4. A barrier potential is set up across the junction Which of the above statements are correct? (a) 1 and 3 (b) 2 and 3 (c) 1 and 4 (d) 2 and 4

Description : Consider the following statements regarding the formation of P-N junctions: 1. Holes diffuse across the junction from P-side to N-side 2. The depletion layer is wiped out. 3. There is continuous flow of current across the junction 4 ... correct? (a) 1 and 3 (b) 2 and 3 (c) 1 and 4 (d) 2 and 4

Last Answer : Ans: (c) When a pn-junction is formed, there will be diffusion of carries across the junctions followed by recombination, and the creation of a depletion layer across which a ... potential is established, which will prevent further diffusion of carries across the junction, leading to equilibrium

A tube of uniform cross sectional sectional area `1 cm^(2)` is closed at one end with semi permeable membrane. A solution having 6g glucose per 100 ml

Description : A tube of uniform cross sectional sectional area `1 cm^(2)` is closed at one end with semi permeable membrane. A solution having 6g glucose per 100 ml

Last Answer : A tube of uniform cross sectional sectional area `1 cm^(2)` is closed at one end with semi permeable membrane. A ... k^(-1)`, density of Hg=13.8 g/cc)

Myelin sheath is produced by (a) astrocytes and Schwann cells (b) oligodendrocytes and osteoclasts (c) osteoclasts and astrocytes (d) Schwann cells and oligodendrocytes.

Description : Myelin sheath is produced by (a) astrocytes and Schwann cells (b) oligodendrocytes and osteoclasts (c) osteoclasts and astrocytes (d) Schwann cells and oligodendrocytes.

Last Answer : (d) Schwann cells and oligodendrocytes.

Myelin sheath is produced by : (1) Astrocytes and Schwann cells (2) Oligodendrocytes and Osteoclasts (3) Osteoclasts and Astrocytes (4) Schwann cells and Oligodendrocytes

Description : Myelin sheath is produced by : (1) Astrocytes and Schwann cells (2) Oligodendrocytes and Osteoclasts (3) Osteoclasts and Astrocytes (4) Schwann cells and Oligodendrocytes

Last Answer : (4) Schwann cells and Oligodendrocytes

Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate

Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate

On average red blood cells live around 120 days. The spleen is the main organ where old red blood cells are destroyed. During the red blood cell destruction the heme groups turn into bilirubin and this substance is then captured by the liver and later excreted in the bowels as part of the bile.

Description : On average red blood cells live around 120 days. The spleen is the main organ where old red blood cells are destroyed. During the red blood cell destruction the heme groups turn into bilirubin and this substance is then captured by the liver and later excreted in the bowels as part of the bile.

Last Answer : What are the functions of the spleen?

Unconjugated bilirubin is derived principally from: C A. glucuronyl transferase activity B. toxic liver injury C. breakdown of senescent red blood cells D. None of these

Description : Unconjugated bilirubin is derived principally from: C A. glucuronyl transferase activity B. toxic liver injury C. breakdown of senescent red blood cells D. None of these

Last Answer : breakdown of senescent red blood cells

A lipid bilayer is permeable to (A) Urea (B) Fructose (C) Glucose (D) Potassium

Description : A lipid bilayer is permeable to (A) Urea (B) Fructose (C) Glucose (D) Potassium

Last Answer : A

Cell membranes a. consist almost entirely of protein molecules b. are impermeable to fat-soluble substances c. in some tissues permit the transport of glucose at a greater rate in the presence of insulin d. are freely permeable to electrolytes but not to proteins e. have a stable composition throughout the life of the cell

Description : Cell membranes a. consist almost entirely of protein molecules b. are impermeable to fat-soluble substances c. in some tissues permit the transport of glucose at a greater rate in the presence of ... to electrolytes but not to proteins e. have a stable composition throughout the life of the cell

Last Answer : in some tissues permit the transport of glucose at a greater rate in the presence of insulin

The main purpose of the Project Management Plan is to: a. provide justification for undertaking the project in terms of evaluating the benefit, cost and risk of alternative options. b. ensure the project sponsor has tight control of the project manager’s activity. c. document the outcomes of the planning process and provide the reference document for managing the project. d. document the outcome of the risk, change and configuration management processes.

Description : The main purpose of the Project Management Plan is to: a. provide justification for undertaking the project in terms of evaluating the benefit, cost and risk of  alternative options. b. ensure ... the  project. d. document the outcome of the risk, change and configuration management processes.

Last Answer : c. document the outcomes of the planning process and provide the reference document for managing the  project.

The main purpose of the Project Management Plan is to: a. provide justification for undertaking the project in terms of evaluating the benefit, cost and risk of alternatd. document the outcome of the risk, change and configuration management processes.ive options. b. ensure the project sponsor has tight control of the project manager’s activity. c. document the outcomes of the planning process and provide the reference document for managing the project.

Description : The main purpose of the Project Management Plan is to:  a. provide justification for undertaking the project in terms of evaluating the benefit, cost and risk  of alternative options.  b ... managing the project. d. document the outcome of the risk, change and configuration management processes.

Last Answer : c. document the outcomes of the planning process and provide the reference document for  managing the project.

Blood brain barrier can be crossed by (A) Epinephrine (B) Dopamine (C) Dopa (D) All of these

Description : Blood brain barrier can be crossed by (A) Epinephrine (B) Dopamine (C) Dopa (D) All of these

Last Answer : Answer : C

A hormone which cannot cross the blood brain barrier is (A) Epinephrine (B) Aldosterone (C) ACTH (D) TSH

Description : A hormone which cannot cross the blood brain barrier is (A) Epinephrine (B) Aldosterone (C) ACTH (D) TSH

Last Answer : Answer : A

Ephedrine is similar to adrenaline in the following feature (a) Potency (b) Inability to penetrate blood-brain barrier (c) Duration of action (d) Producing both a and ß adrenergic effects

Description : Ephedrine is similar to adrenaline in the following feature (a) Potency (b) Inability to penetrate blood-brain barrier (c) Duration of action (d) Producing both a and ß adrenergic effects

Last Answer : Ans: D

Dobutamine differs from dopamine in that (a) It does not activate peripheral dopaminergic receptors (b) It does not activate adrenergic ß receptors (c) It causes pronounced tachycardia (d) It has good blood-brain barrier penetrability

Description : Dobutamine differs from dopamine in that (a) It does not activate peripheral dopaminergic receptors (b) It does not activate adrenergic ß receptors (c) It causes pronounced tachycardia (d) It has good blood-brain barrier penetrability

Last Answer : Ans: A

The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug

Description : The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug

Last Answer : Ans: D

Sulfamethoxypyridazine and other related long acting sulfonamides have now gone into disuse because (a) They have produced serious cutaneous reactions (b) They have produced high incidence of crystalluria (c) They interact with many drugs (d) They do not penetrate blood-brain barrier

Description : Sulfamethoxypyridazine and other related long acting sulfonamides have now gone into disuse because (a) They have produced serious cutaneous reactions (b) They have produced high incidence of crystalluria (c) They interact with many drugs (d) They do not penetrate blood-brain barrier

Last Answer : Ans: A

Why is the blood-brain barrier important?

Description : Why is the blood-brain barrier important? 

Last Answer : The blood-brain barrier is formed by the contacts of special glial cells, called astrocytes, with blood vessels. It is essential for maintaining homeostasis in the brain. In general, only ... the assistance of specific carrier molecules. Some substances cannot pass through the barrier at all. 

The following is not true of morphine: A. Its 2-glucuronide metabolite is an active analgesic B. Its active metabolite penetrates blood-brain barrier better than morphine C. Its oral: parenteral activity ratio is 1:4 D. It undergoes enterohepatic cycling

Description : The following is not true of morphine: A. Its 2-glucuronide metabolite is an active analgesic B. Its active metabolite penetrates blood-brain barrier better than morphine C. Its oral: parenteral activity ratio is 1:4 D. It undergoes enterohepatic cycling

Last Answer : B. Its active metabolite penetrates blood-brain barrier better than morphine

Compared to ****/beef insulins, the human insulins: A. Are more potent B. Have a faster kinetics of absorption and elimination C. Have longer biological action half life D. Penetrate blood-brain barrier more efficiently

Description : Compared to pork/beef insulins, the human insulins: A. Are more potent B. Have a faster kinetics of absorption and elimination C. Have longer biological action half life D. Penetrate blood-brain barrier more efficiently

Last Answer : B. Have a faster kinetics of absorption and elimination

The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Description : The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Last Answer : D. Ratio of H1:H2 blockade produced by the drug

Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects

Description : Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects

Last Answer : D. Producing both α and β adrenergic effects

Dobutamine differs from dopamine in that: A. It does not activate peripheral dopaminergic receptors B. It does not activate adrenergic β receptors C. It causes pronounced tachycardia D. It has good blood-brain barrier penetrability

Description : Dobutamine differs from dopamine in that: A. It does not activate peripheral dopaminergic receptors B. It does not activate adrenergic β receptors C. It causes pronounced tachycardia D. It has good blood-brain barrier penetrability

Last Answer : A. It does not activate peripheral dopaminergic receptors

Weakly acidic drugs: A. Are bound primarily to α1 acid glycoprotein in plasma B. Are excreted faster in alkaline urine C. Are highly ionized in the gastric juice D. Do not cross blood-brain barrier

Description : Weakly acidic drugs: A. Are bound primarily to α1 acid glycoprotein in plasma B. Are excreted faster in alkaline urine C. Are highly ionized in the gastric juice D. Do not cross blood-brain barrier

Last Answer : B. Are excreted faster in alkaline urine

08. What does the term “bioavailability” mean? a) Plasma protein binding degree of substance b) Permeability through the brain-blood barrier c) Fraction of an uncharged drug reaching the systemic circulation following any route administration d) Amount of a substance in urine relative to the initial doze

Description : 08. What does the term bioavailability mean? a) Plasma protein binding degree of substance b) Permeability through the brain-blood barrier c) Fraction of an uncharged drug reaching the systemic ... following any route administration d) Amount of a substance in urine relative to the initial doze

Last Answer : C

06. A hydrophilic medicinal agent has the following property: a) Low ability to penetrate through the cell membrane lipids b) Penetrate through membranes by means of endocytosis c) Easy permeation through the blood-brain barrier d) High reabsorption in renal tubules

Description : 06. A hydrophilic medicinal agent has the following property: a) Low ability to penetrate through the cell membrane lipids b) Penetrate through membranes by means of endocytosis c) Easy permeation through the blood-brain barrier d) High reabsorption in renal tubules

Last Answer : a) Low ability to penetrate through the cell membrane lipids

Weakly acidic drugs: A. Are bound primarily to α1 acid glycoprotein in plasma B. Are excreted faster in alkaline urine C. Are highly ionized in the gastric juice D. Do not cross blood-brain barrier

Description : Weakly acidic drugs: A. Are bound primarily to α1 acid glycoprotein in plasma B. Are excreted faster in alkaline urine C. Are highly ionized in the gastric juice D. Do not cross blood-brain barrier

Last Answer : B. Are excreted faster in alkaline urine

The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Description : The capacity of an antihistaminic to produce sedation depends on the following except: A. Relative affinity for central versus peripheral H1 receptors B. Ability to penetrate blood-brain barrier C. Individual susceptibility D. Ratio of H1:H2 blockade produced by the drug

Last Answer : D. Ratio of H1:H2 blockade produced by the drug

Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects

Description : Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects

Last Answer : D. Producing both α and β adrenergic effects

Dobutamine differs from dopamine in that: A. It does not activate peripheral dopaminergic receptors B. It does not activate adrenergic β receptors C. It causes pronounced tachycardia D. It has good blood-brain barrier penetrability

Description : Dobutamine differs from dopamine in that: A. It does not activate peripheral dopaminergic receptors B. It does not activate adrenergic β receptors C. It causes pronounced tachycardia D. It has good blood-brain barrier penetrability

Last Answer : A. It does not activate peripheral dopaminergic receptors