Aminoglycoside antibiotics have the following common property (a) They are primarily active against gramnegative bacilli (b) They are more active in acidic medium (c) They readily enter cells and are distributed in total body water (d) They are nearly completely metabolized in liver

Aminoglycoside antibiotics have the following common property (a) They are primarily active against gramnegative bacilli (b) They are more active in acidic medium (c) They readily enter cells and are distributed in total body water (d) They are nearly completely metabolized in liver
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Aminoglycoside antibiotics have the following property common to all members: A. They are primarily active against aerobic gram negative bacilli B. They are more active in acidic medium C. They readily enter cells and are distributed in total body water D. They are nearly completely metabolized in liver

Description : Aminoglycoside antibiotics have the following property common to all members: A. They are primarily active against aerobic gram negative bacilli B. They are more active in acidic medium C. They ... cells and are distributed in total body water D. They are nearly completely metabolized in liver

Last Answer : A. They are primarily active against aerobic gram negative bacilli

Which toxic effect of aminoglycoside antibiotics is most irreversible in nature ? (a) Vestibular damage (b) Hearing loss (c) Neuromuscular blockade (d) Kidney damage

Description : Which toxic effect of aminoglycoside antibiotics is most irreversible in nature ? (a) Vestibular damage (b) Hearing loss (c) Neuromuscular blockade (d) Kidney damage

Last Answer : Ans: B

Which of the following is not true of sulfonamides ? (a) They are primarily metabolized by acetylation (b) They are more likely to produce crystalluria in alkaline urine in which they are less soluble (c) They may exert bactericidal action in the urinary tract (d) Used alone, they have become therapeutically unreliable for serious infections

Description : Which of the following is not true of sulfonamides ? (a) They are primarily metabolized by acetylation (b) They are more likely to produce crystalluria in alkaline urine in which they are ... in the urinary tract (d) Used alone, they have become therapeutically unreliable for serious infections

Last Answer : Ans: B

This drug has activity against many strains of Pseudomomas aeruginosa. However, when it is used alone, resistance has emerged during the course of treatment. The drug should not be used in penicillinallergic patients. Its activity against gramnegative rods is enhanced if it is given in combination with tazobactam (a) Amoxicillin (b) Aztreonam (c) Imipenem (d) Piperacillin (e) Vancomycin

Description : This drug has activity against many strains of Pseudomomas aeruginosa. However, when it is used alone, resistance has emerged during the course of treatment. The drug should not be used in ... with tazobactam (a) Amoxicillin (b) Aztreonam (c) Imipenem (d) Piperacillin (e) Vancomycin

Last Answer : Ans: D

Superinfections are more common with (a) Use of narrow spectrum antibiotics (b) Short courses of antibiotics (c) Use of antibiotics that are completely absorbed from the small intestines (d) Use of antibiotic combinations covering both gram positive and gram negative bacteria

Description : Superinfections are more common with (a) Use of narrow spectrum antibiotics (b) Short courses of antibiotics (c) Use of antibiotics that are completely absorbed from the small intestines (d) Use of antibiotic combinations covering both gram positive and gram negative bacteria

Last Answer : Ans: D

In the empiric treatment of severe bacterial infections of unidentified entiology, this drug, often used in combination with an aminoglycoside, provides coverage against many staphylococci (a) Amoxicillin (b) Clavulanic acid (c) Erythromycin (d) Nafcillin (e) Tetracycline

Description : In the empiric treatment of severe bacterial infections of unidentified entiology, this drug, often used in combination with an aminoglycoside, provides coverage against many staphylococci (a) Amoxicillin (b) Clavulanic acid (c) Erythromycin (d) Nafcillin (e) Tetracycline

Last Answer : Ans: D

Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low (b) It is inactivated by the gut microflora (c) It is not active against the microbes of the normal gut flora (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well

Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic ... (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well

Last Answer : Ans: A

Which aminoglycoside antibiotic causes more hearing loss than vestibular disturabance as toxic effect ? (a) Streptomycin (b) Gentamicin (c) Kanamycin (d) Sisomicin

Description : Which aminoglycoside antibiotic causes more hearing loss than vestibular disturabance as toxic effect ? (a) Streptomycin (b) Gentamicin (c) Kanamycin (d) Sisomicin

Last Answer : Ans: C

An aminoglycoside antibiotic should not be used concurrently with the following drug (a) Ampicillin (b) Vancomycin (c) Ciprofloxacin (d) Rifampin

Description : An aminoglycoside antibiotic should not be used concurrently with the following drug (a) Ampicillin (b) Vancomycin (c) Ciprofloxacin (d) Rifampin

Last Answer : Ans: B

The aminoglycoside antibiotic which is distinguished by its resistance to bacterial aminoglycoside inactivating enzymes is (a) Kanamycin (b) Sisomicin (c) Amikacin (d) Tobramycin

Description : The aminoglycoside antibiotic which is distinguished by its resistance to bacterial aminoglycoside inactivating enzymes is (a) Kanamycin (b) Sisomicin (c) Amikacin (d) Tobramycin

Last Answer : Ans: C

The most important mechanism of bacterial resistance to an aminoglycoside antibiotic is (a) Plasmid mediated acquisition of aminoglycoside conjugating enzyme (b) Mutational acquisition of aminoglycoside hydrolyzing enzyme (c) Mutation reducing affinity of ribosomal protein for the antibiotic (d) Mutational loss of porin channels

Description : The most important mechanism of bacterial resistance to an aminoglycoside antibiotic is (a) Plasmid mediated acquisition of aminoglycoside conjugating enzyme (b) Mutational acquisition of aminoglycoside ... affinity of ribosomal protein for the antibiotic (d) Mutational loss of porin channels

Last Answer : Ans: A

Spectinomycin is an aminoglycoside-like antibiotic indicated for the treatment of (a) Gram-negative bacillary septicemia (b) Tuberculosis (c) Penicillin-resistant gonococcal infections (d) Syphilis (e) Gram-negative meningitis due to susceptible organisms

Description : Spectinomycin is an aminoglycoside-like antibiotic indicated for the treatment of (a) Gram-negative bacillary septicemia (b) Tuberculosis (c) Penicillin-resistant gonococcal infections (d) Syphilis (e) Gram-negative meningitis due to susceptible organisms

Last Answer : Ans: C

The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is (a) Decreased permeability into the bacterial cell (b) Acquisition of a plasmid encoded for chloramphenicol acetyl transferase (c) Lowered affinity of the bacterial ribosome for chloramphenicol (d) Switching over from ribosomal to mitochondrial protein synthesis

Description : The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is (a) Decreased permeability into the bacterial cell (b) Acquisition of a plasmid encoded ... bacterial ribosome for chloramphenicol (d) Switching over from ribosomal to mitochondrial protein synthesis

Last Answer : Ans: B

Beta – lactamase production by strains of Haemophilus influenzae, Moraxella catarrhalis, and Neissera gonorrhoeae confers resistance against penicillin G.which one of the following antibiotics is most likely to be effective against all strains of each of the above organisms? (a) Ampicillin (b) Ceftriaxone (c) Clindamycin (d) Gentamicin (e) Piperacillin

Description : Beta - lactamase production by strains of Haemophilus influenzae, Moraxella catarrhalis, and Neissera gonorrhoeae confers resistance against penicillin G.which one of the following antibiotics is most likely to be ... ? (a) Ampicillin (b) Ceftriaxone (c) Clindamycin (d) Gentamicin (e) Piperacillin

Last Answer : Ans: B

Features of clindamycin include the following: A. It is primarily active against aerobic gram negative bacilli B. It can be used topically to treat infected acne vulgaris C. It is not absorbed orally D. It is used to treat pseudomembranous enterocolitis

Description : Features of clindamycin include the following: A. It is primarily active against aerobic gram negative bacilli B. It can be used topically to treat infected acne vulgaris C. It is not absorbed orally D. It is used to treat pseudomembranous enterocolitis

Last Answer : B. It can be used topically to treat infected acne vulgaris

Nalidixic acid is primarily active against: A. Cocci B. Bacilli C. Gram positive bacteria D. Gram negative bacteria

Description : Nalidixic acid is primarily active against: A. Cocci B. Bacilli C. Gram positive bacteria D. Gram negative bacteria

Last Answer : D. Gram negative bacteria

Chloramphenicol is more active than tetracyclines against (a) Bateroides fragilis (b) Treponema pallidum (c) Streptococci (d) Staphylococci

Description : Chloramphenicol is more active than tetracyclines against (a) Bateroides fragilis (b) Treponema pallidum (c) Streptococci (d) Staphylococci

Last Answer : Ans: A

Piperacillin differs from carbenicillin in the following respect(s) (a) It is more active against pseudomonas aeruginosa (b) It is active against Klebsiella also (c) It is acid resistant (d) Both (a) and (b)

Description : Piperacillin differs from carbenicillin in the following respect(s) (a) It is more active against pseudomonas aeruginosa (b) It is active against Klebsiella also (c) It is acid resistant (d) Both (a) and (b)

Last Answer : Ans: D

Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it (a) Eradicates mycoplasmal infections in a single dose (b) Is active against strains of streptococci that are resistant to erythromycin (c) Is more active against Mycobacterium avium complex (d) Does not inhibit live drug-metabolizing enzymes (e) Acts on methicillin-resistant strains of staphylococci

Description : Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it (a) Eradicates mycoplasmal infections in a single dose (b ... not inhibit live drug-metabolizing enzymes (e) Acts on methicillin-resistant strains of staphylococci

Last Answer : Ans: C

Cefotaxime has the following properties except (a) It is highly active against aerobic gram negative bacteria (b) It is the most active cephalosporin against Pseudomonas aeruginosa (c) It produces an active metabolite (d) It has achieved high cure rates in serious hospital acquired infections

Description : Cefotaxime has the following properties except (a) It is highly active against aerobic gram negative bacteria (b) It is the most active cephalosporin against Pseudomonas aeruginosa (c) It produces an active metabolite (d) It has achieved high cure rates in serious hospital acquired infections

Last Answer : Ans: B

Amoxicillin + Clavulanic acid is active against the following organism except (a) Methicillin resistant Staph. aureus (b) Penicillinase producing Staph. aureus (c) Penicillinase producing n. gonorrhoeae (d) ß-lactamase producing E. coli

Description : Amoxicillin + Clavulanic acid is active against the following organism except (a) Methicillin resistant Staph. aureus (b) Penicillinase producing Staph. aureus (c) Penicillinase producing n. gonorrhoeae (d) ß-lactamase producing E. coli

Last Answer : Ans: A

Which one of the following statements about cefotetan is accurate? (a) It is active against MRSA strains (b) It is the drug of choice in community-acquired pneumonia (c) It is a fourth-generation cephalosporin (d) It decreases prothrombin time (e) Its antibacterial spectrum include Bacteroides fragilis

Description : Which one of the following statements about cefotetan is accurate? (a) It is active against MRSA strains (b) It is the drug of choice in community-acquired pneumonia (c) ... fourth-generation cephalosporin (d) It decreases prothrombin time (e) Its antibacterial spectrum include Bacteroides fragilis

Last Answer : Ans: E

The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes and inhibit bacterial protein synthesis (c) They bind to 50S ribosomes and interfere with translocation of the growing peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria

Description : The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes ... peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria

Last Answer : Ans: B

Methicillin resistant staphylococci do not respond to ß-lactam antibiotics because (a) They produce a ß-lactamase which destroys methicillin and related drugs (b) They elaborate an amidase which destroys methicillin and related drugs (c) They have acquired a penicillin binding protein which has low affinity for ß-lactam antibiotics (d) They are less permeable to ß-lactam antibiotics

Description : Methicillin resistant staphylococci do not respond to ß-lactam antibiotics because (a) They produce a ß-lactamase which destroys methicillin and related drugs (b) They elaborate an amidase which destroys ... low affinity for ß-lactam antibiotics (d) They are less permeable to ß-lactam antibiotics

Last Answer : Ans: C

Anyone else terrified of taking antibiotics? How do you cope?

Description : Anyone else terrified of taking antibiotics? How do you cope?

Last Answer : KEEP TAKING IT! If the bad bacteria in your system doesn’t get killed off by the antibiotics you’re taking, they could come back stronger that ever! So strong that no antibiotic will kill them and then they will kill YOU!!! So KEEP TAKING IT like the good doctor said!!!

Anyone else scared of taking antibiotics due to reactions?

Description : Anyone else scared of taking antibiotics due to reactions?

Last Answer : Every single freaking thing you put in your mouth can have side effects. No, I’m not going to beat myself up over something so unlikely to happen.

Had anyone got rid of strep throat without taking antibiotics?

Description : Had anyone got rid of strep throat without taking antibiotics?

Last Answer : I’ve had them on and off since I had mono in junior high. I burn it out with scalding tea, then soothe with gargling salt water. Good luck. Go see a doctor though for real please.

Do anti-vaxxers also eschew things like tetanus shots and antibiotics?

Description : Do anti-vaxxers also eschew things like tetanus shots and antibiotics?

Last Answer : Some do I am sure. I am anti- OVER vaccinating, and this is why I won't be re-vaccinating my 7 and 10 yr. old cats that are indoors only at this time. They have enough immunity ... horses. Horses are highly susceptible to Tetanus, more so than other farm animals, though they are vaccinated as well.

Antibiotics causing swollen lymph nodes under jawline?

Description : Antibiotics causing swollen lymph nodes under jawline?

Last Answer :

Can a course of antibiotics leave you feeling very run down?

Description : Can a course of antibiotics leave you feeling very run down?

Last Answer : Absolutely.

Ear Infection - to take or not to take antibiotics?

Description : Ear Infection - to take or not to take antibiotics?

Last Answer : Any delay in treating an ear infection increases the odds of permanent damage. If I were you, I’d start the azithromycin immediately. Take the front load with food. It will be easier on your stomach.

Are there any kinds of drinks that can counteract the effect of antibiotics?

Description : Are there any kinds of drinks that can counteract the effect of antibiotics?

Last Answer : Anything with alcohol in it. Depending on the tablet milk can slow the rate of absorption

Can you smoke marijuana while on antibiotics?

Description : Can you smoke marijuana while on antibiotics?

Last Answer : Not legally.

Which out of the following antibiotics penetrates blood-CSF barrier the best (a) Erythromycin (b) Gentamicin (c) Tetracycline (d) Chloramphenicol

Description : Which out of the following antibiotics penetrates blood-CSF barrier the best (a) Erythromycin (b) Gentamicin (c) Tetracycline (d) Chloramphenicol

Last Answer : Ans: D

Widespread and prolonged used of an antibiotic leads to emergence of drug resistant strains because antibiotics (a) Induce mutation in the bacteria (b) Promote conjugation among bacteria (c) Allow resistant strains to propagate preferentially (d) All of the above

Description : Widespread and prolonged used of an antibiotic leads to emergence of drug resistant strains because antibiotics (a) Induce mutation in the bacteria (b) Promote conjugation among bacteria (c) Allow resistant strains to propagate preferentially (d) All of the above

Last Answer : Ans: C

Which one of the following antibiotics is a potent inducer of hepatic drug-metabolizing enzymes? (a) Ciprofloxacin (b) Cyclosporine (c) Erythromycin (d) Rifampin (e) Tetracycline

Description : Which one of the following antibiotics is a potent inducer of hepatic drug-metabolizing enzymes? (a) Ciprofloxacin (b) Cyclosporine (c) Erythromycin (d) Rifampin (e) Tetracycline

Last Answer : Ans: D

Which one of the following antibiotics is likely to be most effective agent in the treatment of an infection due to enterococci if used in conjuction with penicillin G? (a) Amikacin (b) Gentamicin (c) Netilmicin (d) Streptomycin (e) Tobramycin

Description : Which one of the following antibiotics is likely to be most effective agent in the treatment of an infection due to enterococci if used in conjuction with penicillin G? (a) Amikacin (b) Gentamicin (c) Netilmicin (d) Streptomycin (e) Tobramycin

Last Answer : Ans: D

The primary mechanism underlying the resistance of gram-positive organisms to macrolide antibiotics is (a) Methylation of binding sites on the 50S ribosomal subunit (b) Formation of esterases that hydrolyze the lactone ring (c) Increased activity of efflux mechanisms (d) Formation of drug-inactivating acetyltranferases (e) Decreased drug permeability of the cytoplasmic membrane

Description : The primary mechanism underlying the resistance of gram-positive organisms to macrolide antibiotics is (a) Methylation of binding sites on the 50S ribosomal subunit (b) Formation of ... ) Formation of drug-inactivating acetyltranferases (e) Decreased drug permeability of the cytoplasmic membrane

Last Answer : Ans: A

The antibacterial action of aminoglycoside antibiotics is characterized by: A. Concentration dependent rate of bacterial cell killing B. Concentration dependent prolonged postantibiotic effect C. More pronounced bactericidal effect in anaerobic medium D. Both 'A' and 'B' are correct

Description : The antibacterial action of aminoglycoside antibiotics is characterized by: A. Concentration dependent rate of bacterial cell killing B. Concentration dependent prolonged postantibiotic effect C. More pronounced bactericidal effect in anaerobic medium D. Both 'A' and 'B' are correct

Last Answer : D. Both 'A' and 'B' are correct

In the treatment of typhoid fever, ciprofloxacin has the following advantage(s) (a) It is effective in nearly all cases (b) Early abetment of fever and other symptoms (c) Development of carrier state is less likely (d) All of the above

Description : In the treatment of typhoid fever, ciprofloxacin has the following advantage(s) (a) It is effective in nearly all cases (b) Early abetment of fever and other symptoms (c) Development of carrier state is less likely (d) All of the above

Last Answer : Ans: D

Indicate the sulfonamide whose sodium salt yields a nearly neutral solution which is suitable for topical use in the eye (a) Sulfadiazine (b) Sulfacetamide (c) Sulfamerazine (d) Sulfamethizole

Description : Indicate the sulfonamide whose sodium salt yields a nearly neutral solution which is suitable for topical use in the eye (a) Sulfadiazine (b) Sulfacetamide (c) Sulfamerazine (d) Sulfamethizole

Last Answer : Ans: B

Adverse effects of ciprofloxacin are referable primarily to the following except (a) Gastrointestinal tract (b) Kidney (c) Skin (d) Nervous system

Description : Adverse effects of ciprofloxacin are referable primarily to the following except (a) Gastrointestinal tract (b) Kidney (c) Skin (d) Nervous system

Last Answer : Ans: B

The following is true for gentamicin: A. It is more active in acidic medium B. It has a wide margin of safety C. It is excreted unchanged, mainly by glomerular filtration D. It primarily inhibits gram positive bacteria

Description : The following is true for gentamicin: A. It is more active in acidic medium B. It has a wide margin of safety C. It is excreted unchanged, mainly by glomerular filtration D. It primarily inhibits gram positive bacteria

Last Answer : C. It is excreted unchanged, mainly by glomerular filtration

Which antimicrobial should be avoided in patients of liver disease ? (a) Chlortetracycline (b) Cotrimoxazole (c) Cephalexin (d) Ethambutol

Description : Which antimicrobial should be avoided in patients of liver disease ? (a) Chlortetracycline (b) Cotrimoxazole (c) Cephalexin (d) Ethambutol

Last Answer : Ans: A

Adrenaline is inactive orally because it is: A. Not absorbed from the gastrointestinal tract B. Destroyed by gastric acid C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation D. Taken up by adrenergic nerve endings of the intestinal wall, liver and lungs

Description : Adrenaline is inactive orally because it is: A. Not absorbed from the gastrointestinal tract B. Destroyed by gastric acid C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation D. Taken up by adrenergic nerve endings of the intestinal wall, liver and lungs

Last Answer : C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation

Adrenaline is inactive orally because it is: A. Not absorbed from the gastrointestinal tract B. Destroyed by gastric acid C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation D. Taken up by adrenergic nerve endings of the intestinal wall, liver and lungs

Description : Adrenaline is inactive orally because it is: A. Not absorbed from the gastrointestinal tract B. Destroyed by gastric acid C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation D. Taken up by adrenergic nerve endings of the intestinal wall, liver and lungs

Last Answer : C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation

The following are true about calcium regulating hormones: a. calcitonin increases the plasma calcium concentration b. vitamin D is produced in the skin c. vitamin D is metabolized to its active form in the liver and kidney. d. vitamin D increases calcium absorption from the gut

Description : The following are true about calcium regulating hormones: a. calcitonin increases the plasma calcium concentration b. vitamin D is produced in the skin c. vitamin D is metabolized to its active form in the liver and kidney. d. vitamin D increases calcium absorption from the gut

Last Answer : vitamin D increases calcium absorption from the gut

Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellular(MAI)? (a) Vancomycin (b) Clarithromycin (c) Erythromycin base (d) Troleandomycin (e) Erythromycin estolate

Description : Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellular(MAI)? (a) Vancomycin (b) Clarithromycin (c) Erythromycin base (d) Troleandomycin (e) Erythromycin estolate

Last Answer : Ans: B