Description : Chloramphenicol is more active than tetracyclines against: A. Bateroides fragilis B. Treponema pallidum C. Streptococci D. Staphylococci
Last Answer : a
Description : Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it (a) Eradicates mycoplasmal infections in a single dose (b ... not inhibit live drug-metabolizing enzymes (e) Acts on methicillin-resistant strains of staphylococci
Last Answer : Ans: C
Description : Cloxacillin is indicated in infections caused by the following organism(s) (a) Staphylococci (b) Streptococci (c) Gonococci (d) All of the above
Last Answer : Ans: A
Description : Which of the following organisms is notorious for developing antimicrobial resistance rapidly ? (a) Streptococcus pyogenes (b) Meningococcus (c) Treponema pallidum (d) Escherichia coli
Last Answer : Ans: D
Description : Which one of the following statements about cefotetan is accurate? (a) It is active against MRSA strains (b) It is the drug of choice in community-acquired pneumonia (c) ... fourth-generation cephalosporin (d) It decreases prothrombin time (e) Its antibacterial spectrum include Bacteroides fragilis
Last Answer : Ans: E
Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic ... (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well
Description : In the empiric treatment of severe bacterial infections of unidentified entiology, this drug, often used in combination with an aminoglycoside, provides coverage against many staphylococci (a) Amoxicillin (b) Clavulanic acid (c) Erythromycin (d) Nafcillin (e) Tetracycline
Description : Methicillin resistant staphylococci do not respond to ß-lactam antibiotics because (a) They produce a ß-lactamase which destroys methicillin and related drugs (b) They elaborate an amidase which destroys ... low affinity for ß-lactam antibiotics (d) They are less permeable to ß-lactam antibiotics
Description : Tetracyclines are still the first choice drugs for the following disease. (a) Granuloma linguinale (b) Chancroid (c) Syphilis (d) Gonorrhoea in patients allergic to penicillin
Description : Highest incidence of antibiotic associated pseudo membranous enterocolitis has been noted with the use of (a) Ampicillin (b) Chloramphenicol (c) Vancomycin (d) Clindamycin
Description : What is the most important reason for restricted clinical use of chloramphenicol ? (a) Its narrow spectrum of activity (b) Emergence of chloramphenicol resistance (c) Its potential to cause bone marrow depression (d) Its potential to cause superinfections
Description : The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is (a) Decreased permeability into the bacterial cell (b) Acquisition of a plasmid encoded ... bacterial ribosome for chloramphenicol (d) Switching over from ribosomal to mitochondrial protein synthesis
Last Answer : Ans: B
Description : Which out of the following antibiotics penetrates blood-CSF barrier the best (a) Erythromycin (b) Gentamicin (c) Tetracycline (d) Chloramphenicol
Description : An 8-year-old child presented with brownish discoloured and deformed anterior teeth. History of having received an antibiotic about 4 years earlier was obtained. Which antibiotic could be responsible for the condition ? (a) Chloramphenicol (b) Tetracycline (c) Erythromycin (d) Genetamicin
Description : Currently the drug of choice for emperic treatment of typhoid fever is (a) Chloramphenicol (b) Cotrimoxaxole (c) Ciprofloxacin (d) Ampicillin
Description : Select the antibiotic whose dose must be reduced in patients with renal insufficiency (a) Ampicillin (b) Chloramphenicol (c) Tobramycin (d) Erythromycin
Description : Chloramphenicol is particularly effective in the treatment of (a) Diphtheria (b) Tuberculosis (c) Emphysema (d) Rickettsial diseases (e) Streptomyces pyogenes infections
Description : The appearance of markedly vacuolated, nucleated red cells in the marrow, anemia, and reticulocytopenia are characteristic dose-dependent side effects of (a) Azithromycin (b) Chloramphenicol (c) Clindamycin (d) Doxycycline (e) Linezolid
Description : Which of the following skin conditions is caused by staphylococci, streptococci, or multiple bacteria? a) Impetigo Impetigo is seen at all ages, but is particularly common among children living under poor ... ivy is a contact dermatitis caused by the oleoresin given off by a particular form of ivy.
Last Answer : a) Impetigo Impetigo is seen at all ages, but is particularly common among children living under poor hygienic conditions.
Description : Cloxacillin is indicated in infections caused by the following organism(s): A. Staphylococci B. Streptococci C. Gonococci D. All of the above
Last Answer : A. Staphylococc
Description : Which one of the following does correctly match a sexually transmitted disease with its pathogen? (a) Syphilis-Treponema pallidum (b) Gonorrhoea-Entamoeba histolytica (c) Urethritis-Bacillus anthracis (d) Softsore-Bacillus brevis
Last Answer : a) Syphilis-Treponema pallidum
Description : Which is showing accurate pairing? (a) Syphilis - Treponema pallidum (b) AIDS - Bacillus conjugalis (c) Gonorrhoea - Leishmania donovani (d) Typhoid - Mycobacterium leprae
Last Answer : (a) Syphilis - Treponema pallidum
Description : Match the disease in column I with the appropriate items (pathogen / prevention / treatment) in column II. Column I Column II A. Amoebiasis (i) Treponema pallidum B. Diphtheria (ii) Use only sterilised food and water C. Cholera (iii)DPT ... D - (iv) (d) A - (ii), B - (iv), C - (i), D - (iii)
Last Answer : (b) A – (ii), B – (iii), C – (iv), D – (i)
Description : Organisms that normally inhabit the body a. include Treponema pallidum. b. cause endogenous diseases. c. may be detected by Donovan bodies. d. resist the effects of antibiotics.
Last Answer : b. cause endogenous diseases.
Description : The most common cause of an invasive wound infection, such as a burn, is a. gram-positive bacterial species. b. treponema pallidum. c. Pseudomonas aeruginosa. d. Escherichia coli.
Last Answer : c. Pseudomonas aeruginosa.
Description : Aminoglycoside antibiotics have the following common property (a) They are primarily active against gramnegative bacilli (b) They are more active in acidic medium (c) They readily enter cells and are distributed in total body water (d) They are nearly completely metabolized in liver
Description : Piperacillin differs from carbenicillin in the following respect(s) (a) It is more active against pseudomonas aeruginosa (b) It is active against Klebsiella also (c) It is acid resistant (d) Both (a) and (b)
Description : Cefotaxime has the following properties except (a) It is highly active against aerobic gram negative bacteria (b) It is the most active cephalosporin against Pseudomonas aeruginosa (c) It produces an active metabolite (d) It has achieved high cure rates in serious hospital acquired infections
Description : Amoxicillin + Clavulanic acid is active against the following organism except (a) Methicillin resistant Staph. aureus (b) Penicillinase producing Staph. aureus (c) Penicillinase producing n. gonorrhoeae (d) ß-lactamase producing E. coli
Description : The following antibiotic is highly active against anaerobic bacteria including Bacteroides fragilis: A. Ciprofloxacin B. Clarithromycin C. Clindamycin D. Tobramycin
Last Answer : C. Clindamycin
Description : Ciprofloxacin is not active against: A. H.influenzae B. E.coli C. Enterobacter spp. D. Bacteroides fragilis
Last Answer : D. Bacteroides fragilis
Description : Drug destroying type of bacterial resistance is important for the following antibiotics except: A. Cephalosporins B. Tetracyclines C. Chloramphenicol D. Aminoglycosides
Last Answer : B. Tetracyclines
Description : Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellular(MAI)? (a) Vancomycin (b) Clarithromycin (c) Erythromycin base (d) Troleandomycin (e) Erythromycin estolate
Description : Which fluoroquinolone has markedly enhanced activity against gram positive bacteria and anaerobes ? (a) Pefloxacin (b) Ciprofloxacin (c) Sparfloxacin (d) Norfloxacin
Description : Beta - lactamase production by strains of Haemophilus influenzae, Moraxella catarrhalis, and Neissera gonorrhoeae confers resistance against penicillin G.which one of the following antibiotics is most likely to be ... ? (a) Ampicillin (b) Ceftriaxone (c) Clindamycin (d) Gentamicin (e) Piperacillin
Description : Which one of the following drugs is most likely to be effective against multidrug – resistant strains of M tuberculosis, including those resistant to streptomycin? (a) Amikacin (b) Clarithromycin (c) Gentamicin (d) Meropenem (e) Spectinomycin
Description : This drug has activity against many strains of Pseudomomas aeruginosa. However, when it is used alone, resistance has emerged during the course of treatment. The drug should not be used in ... with tazobactam (a) Amoxicillin (b) Aztreonam (c) Imipenem (d) Piperacillin (e) Vancomycin
Description : Tetracyclines are active against the following gram negative bacteria: A. Salmonella typhi B. Pseudomonas aeruginosa C. Yersinia pestis D. All of the above
Last Answer : C. Yersinia pestis
Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because: A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents ... the microbes of the normal gut flora D. It is a potent tetracycline and inhibits
Last Answer : A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low
Description : Which aminoglycoside antibiotic causes more hearing loss than vestibular disturabance as toxic effect ? (a) Streptomycin (b) Gentamicin (c) Kanamycin (d) Sisomicin
Description : Bleomycin is used in most effective drug combination regiment for the chemotherapy of testicular carcinoma. Which one of the following statements about the drug is accurate? (a) Acts mainly in the ... neuropathy occurs in more than 50% of patients (e) Pulmonary infiltrates and fibrosis may occur
Description : Regarding the recently introduced lipid formulation of amphotericin B, which one of the following statements is accurate? (a) Affinity of amphotericin B for these lipids is greater than ... (e) They have wider spectrums of antifungal activity than conventional formulations of amphotericin B
Description : Which one of the following statements about one daily dosing with aminoglycosides is false ? (a) It is convenient for outpatient therapy (b) Adjustment of dosage is less important in renal ... often less toxic than conventional (multiple)dosing regimens (e) Under-dosing is less of a problem
Description : Regarding the antibacterial action of gentamicin, which one of the following statements is most accurate? (a) Efficacy is directly proportionate to the time that the plasma level of the drug is ... an inhibitor of cell wall synthesis (e) The antibacterial action of gentamicin is time - dependent
Description : Roxithromycin has the following advantages over erythromycin except (a) It is more effective in whooping cough (b) It causes less gastric irritation (c) It has longer plasma half-life (d) It is unlikely to precipitate theophylline toxicity
Description : Benzathine penicillin injected once every 4 weeks for 5 years or more is the drug of choice for (a) Agranulocytosis patients (b) Prophylaxis of bacterial endocarditis in patients with valvular defects (c) Prophylaxis of rheumatic fever (d) Treatment of anthrax
Description : Which of the following is not true of sulfonamides ? (a) They are primarily metabolized by acetylation (b) They are more likely to produce crystalluria in alkaline urine in which they are ... in the urinary tract (d) Used alone, they have become therapeutically unreliable for serious infections
Description : Superinfections are more common with (a) Use of narrow spectrum antibiotics (b) Short courses of antibiotics (c) Use of antibiotics that are completely absorbed from the small intestines (d) Use of antibiotic combinations covering both gram positive and gram negative bacteria
Description : An advantge of betamethasone acetate over betamethasone sodium phosphate is (a) Fewer allergic reactions (b) Prompter action (c) More sustained action (d) Greater solubility (e) There is no advantage