Amoxicillin + Clavulanic acid is active against the following organism except (a) Methicillin resistant Staph. aureus (b) Penicillinase producing Staph. aureus (c) Penicillinase producing n. gonorrhoeae (d) ß-lactamase producing E. coli

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Ans: A

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Description : Amoxicillin + Clavulanic acid is active against the following organisms except: A. Methicillin resistant Staph. aureus B. Penicillinase producing Staph. aureus C. Penicillinase producing N.gonorrhoeae D. β-lactamase producing E.coli

Last Answer : A. Methicillin resistant Staph. aureus

Description : Methicillin resistant staphylococci do not respond to ß-lactam antibiotics because (a) They produce a ß-lactamase which destroys methicillin and related drugs (b) They elaborate an amidase which destroys ... low affinity for ß-lactam antibiotics (d) They are less permeable to ß-lactam antibiotics

Last Answer : Ans: C

Description : The following statement is not true of sulbactam: A. It is a broad spectrum β-lactamase inhibitor B. It does not augment the activity of ampicillin against bacteria that are sensitive ... β-lactamases D. Combined with ampicillin, it is highly effective against penicillinase producing N. gonorrhoeae

Last Answer : C. It induces chromosomal β-lactamases

Description : Beta - lactamase production by strains of Haemophilus influenzae, Moraxella catarrhalis, and Neissera gonorrhoeae confers resistance against penicillin G.which one of the following antibiotics is most likely to be ... ? (a) Ampicillin (b) Ceftriaxone (c) Clindamycin (d) Gentamicin (e) Piperacillin

Last Answer : Ans: B

Description : In the empiric treatment of severe bacterial infections of unidentified entiology, this drug, often used in combination with an aminoglycoside, provides coverage against many staphylococci (a) Amoxicillin (b) Clavulanic acid (c) Erythromycin (d) Nafcillin (e) Tetracycline

Last Answer : Ans: D

Description : The drug of choice for treatment of methicillin resistant Staphylococcus aureus infection is (a) Cloxacillin (b) Vancomycin (c) Erythromycin (d) Amikacin

Last Answer : Ans: B

Description : Sulbactam differs from clavulanic acid in that: A. It is not a progressive inhibitor of β-lactamase B. It does not inhibit β-lactamase produced by gram negative bacilli C. It is quantitatively more potent D. It per se inhibits N.gonorrhoeae

Last Answer : D. It per se inhibits N.gonorrhoeae

Description : Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it (a) Eradicates mycoplasmal infections in a single dose (b ... not inhibit live drug-metabolizing enzymes (e) Acts on methicillin-resistant strains of staphylococci

Last Answer : Ans: C

Description : The drug of choice for penicillinase producing Neisseria gonorrhoeae urethritis is: A. Amoxicillin B. Erythromycin C. Ceftriaxone D. Doxycycline

Last Answer : C. Ceftriaxone

Description : Clavulanic acid is combined with amoxicillin because (a) It kills bacteria that are not killed by-moxicillin (b) It reduces renal clearance of amoxicillin (c) It counteracts the adverse effects of amoxicillin (d) It inhibits beta lactamases that destroy amoxicillin

Last Answer : Ans: D

Description : Choose the semisynthetic penicillin which has an extended spectrum of activity against many gram negative bacilli, is acid resistant but not penicillinase resistant: A. Cloxacillin B. Amoxicillin C. Phenoxymethyl penicillin D. Piperacillin

Last Answer : B. Amoxicillin

Description : Piperacillin differs from carbenicillin in the following respect(s) (a) It is more active against pseudomonas aeruginosa (b) It is active against Klebsiella also (c) It is acid resistant (d) Both (a) and (b)

Last Answer : Ans: D

Description : Methicillin resistant staphylococci do not respond to β-lactam antibiotics because: A. They produce a β-lactamase which destroys methicillin and related drugs B. They elaborate an amidase which destroys ... low affinity for β-lactam antibiotics D. They are less permeable to β-lactam antibiotics

Last Answer : C. They have acquired penicillin binding protein which has low affinity for β-lactam antibioti

Description : This drug has activity against many strains of Pseudomomas aeruginosa. However, when it is used alone, resistance has emerged during the course of treatment. The drug should not be used in ... with tazobactam (a) Amoxicillin (b) Aztreonam (c) Imipenem (d) Piperacillin (e) Vancomycin

Last Answer : Ans: D

Description : Which of the following statements about vancomycin is accurate? (a) It is bacteriostatic (b) It binds to PBPs (c) It is not susceptible to penicillinase (d) It has the advantage of oral bioavailability (e) Staphylococcal enterocolitis occurs commonly with its use

Last Answer : Ans: C

Description : Select the antimicrobial agent that can be used to treat with both methicillin resistant and vancomycin resistant Staphylococcus aureus infection: A. Clarithromycin B. Clindamycin C. Linezolid D. Lincomycin

Last Answer : C. Linezolid

Description : A woman’s neglected hangnail has developed into a mild staphylococcal cellulites. Which of the following regimens would be appropriate oral therapy? (a) Dicloxacillin 125 mg q6h (b) Vancomycin 250 mg q6h (c) Methicillin 500 mg q6h (d) Cefazolin 1 g q8h (e) Penicillin V 500 mg q6h

Last Answer : Ans: A

Description : Gram negative organisms are largely insensitive to benzyl penicillin because (a) They produce large quantities of penicillinase (b) They do not utilize D-alanine whose incorporation in the cell wall is ... lipoprotein-peptidoglycan multiplayer cell wall of gram-negative bacteria (d) Both (a) and (b)

Last Answer : Ans: C

Description : Which of the following organism can penetrate intact corneal epithelium? A. Strept pyogenes B. Staph aureus C. Pseudomonas pyocyanaea D. Corynebacterium diphtheriae 

Last Answer : ANSWER: D

Description : Cefotaxime has the following properties except (a) It is highly active against aerobic gram negative bacteria (b) It is the most active cephalosporin against Pseudomonas aeruginosa (c) It produces an active metabolite (d) It has achieved high cure rates in serious hospital acquired infections

Last Answer : Ans: B

Description : A woman has an upper respiratory infection. Six years ago, she experienced an episode of bronchospasm follwing penicillin V therapy. The cultures now reveal a strain of streptococcus pneumoniae that is ... ? (a) Amoxicillin/clavulanate (b) Erythromycin (c) Ampicillin (d) cefaclor (e) Cyclacillin

Last Answer : Ans: B

Description : Your 23-year-old female patient is pregnant and has gonorrhea. The past medical history includes anaphylaxis following exposure to amoxicillin. Worried about compliance, you would like to treat this patient ... chose (a) Cefixime (b) Ceftriaxone (c) Ciprofloxacin (d) Spectinomycin (e) Tetracycline

Last Answer : Ans: D

Description : A patient needs antibiotic treatment for native valve, culture-positive infective enterococcal endocarditis. His medical history includes a severe anaphylactic reaction to penicillin G during the past year. ... /clavulanate (b) Aztreonam (c) Cefazolin plus genatamicin (d) Meropenem (e) Vancomycin

Last Answer : Ans: E

Description : Medical Jellies: has Amoxicillin fallen out of favor for treatment of bronchial infections?

Last Answer : answer:I'm thinking your probably take Amoxicillin Clauvanate? If so, patients and doctors tend to prescribe other drugs that don't destroy the normal flora in the intestines and vagina as much. Also, amox clauv is ... still take it, because it is so good for the rest of my body, but I request it.

Description : Amoxicillin is inferior to ampicillin for the treatment of the following infection (a) Typhoid (b) Shigella enteritis (c) Subacute bacterial endocarditis (d) Gonorrhoea

Last Answer : Ans: B

Description : Which one of the following drugs is most likely to be effective against multidrug – resistant strains of M tuberculosis, including those resistant to streptomycin? (a) Amikacin (b) Clarithromycin (c) Gentamicin (d) Meropenem (e) Spectinomycin

Last Answer : Ans: A

Description : Clavulanic acid is combined with amoxicillin because: A. It kills bacteria that are not killed by amoxicillin B. It retards renal excretion of amoxicillin C. It counteracts the adverse effects of amoxicillin D. It inhibits beta lactamases that destroy amoxicillin

Last Answer : D. It inhibits beta lactamases that destroy amoxicillin

Description : Select the drug combination which does not exhibit supraadditive synergism: A. Nalidixic acid + Nitrofurantoin B. Amoxicillin + Clavulanic acid C. Pyrimethamine + Sulfadoxine D. Sulfamethoxazole + Trimethoprim

Last Answer : A. Nalidixic acid + Nitrofurantoin

Description : A man has an Escherichia coli bacteremia with a low-grade fever (101.6°F). Appropriate management of his fever would be (a) Give acetaminophen 650 mg orally every 4 hours (b) Give aspirin 650 ... fever curve to monitor his response to antibiotic therapy (e) Use tepid water baths to reduce the fever

Last Answer : Ans: D

Description : Which one of the following statements about cefotetan is accurate? (a) It is active against MRSA strains (b) It is the drug of choice in community-acquired pneumonia (c) ... fourth-generation cephalosporin (d) It decreases prothrombin time (e) Its antibacterial spectrum include Bacteroides fragilis

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Description : Which of the following organisms is notorious for developing antimicrobial resistance rapidly ? (a) Streptococcus pyogenes (b) Meningococcus (c) Treponema pallidum (d) Escherichia coli

Last Answer : Ans: D

Description : Aminoglycoside antibiotics have the following common property (a) They are primarily active against gramnegative bacilli (b) They are more active in acidic medium (c) They readily enter cells and are distributed in total body water (d) They are nearly completely metabolized in liver

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Description : Chloramphenicol is more active than tetracyclines against (a) Bateroides fragilis (b) Treponema pallidum (c) Streptococci (d) Staphylococci

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Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic ... (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well

Last Answer : Ans: A

Description : Spectinomycin is an aminoglycoside-like antibiotic indicated for the treatment of (a) Gram-negative bacillary septicemia (b) Tuberculosis (c) Penicillin-resistant gonococcal infections (d) Syphilis (e) Gram-negative meningitis due to susceptible organisms

Last Answer : Ans: C

Description : What is break point concentration of an antibiotic ? (a) Concentration at which the antibiotic lyses the bacteria (b) Concentration of the antibiotic which demarks between sensitive ... which overcomes bacterial resistance (d) Concentration at which a bacteriostatic antibiotic becomes bactericidal

Last Answer : Ans: B

Description : Widespread and prolonged used of an antibiotic leads to emergence of drug resistant strains because antibiotics (a) Induce mutation in the bacteria (b) Promote conjugation among bacteria (c) Allow resistant strains to propagate preferentially (d) All of the above

Last Answer : Ans: C

Description : : All the following are among the opportunistic organisms that may cause nosocomial disease except: a. Pseudomonas aeruginosa. b. Escherichia coli. c. Staphylococcus aureus. d. Mycobacterium leprae.

Last Answer : d. Mycobacterium leprae.

Description : The drug of choice for treatment of methicillin resistant Staphylococcus aureus infection is: A. Cloxacillin B. Vancomycin C. Erythromycin D. Amikacin

Last Answer : B. Vancomycin

Description : Will there be Salmonella and Staph. aureus found in my plate counts from raw, refrigerated pork after incubation? Which bacteria am I expected to see in this type of meat? Thanks.

Last Answer : Listera.

Description : Staph aureus food poisoning?

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Description : In chicken, Staph. aureus is mainly responsible for A A. Purulent arthritis B. Enteritis C. Pneumonia D. None of the these

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Description : Semisynthetic penicillins developed so far have overcome the following drawbacks of benzylpenicillin except: A. Lack of efficacy against gram negative bacilli B. Susceptibility to bacterial penicillinase C. Inactivation by gastric acid D. Potential to cause hypersensitivity reactions

Last Answer : D. Potential to cause hypersensitivity reactions

Description : Cloxacillin is indicated in infections caused by the following organism(s) (a) Staphylococci (b) Streptococci (c) Gonococci (d) All of the above

Last Answer : Ans: A

Description : Which type of antimicrobial drug combination is most likely to exhibit antagonism ? (a) Bactericidal + Bactericidal (b) Bactericidal + Bacteriostatic for a highly sensitive organism (c) Bactericidal + Bacteriostatic for a marginally sensitive organism (d) Bacteriostatic + Bacteriostatic

Last Answer : Ans: B

Description : Penicillins interfere with bacterial cell wall synthesis by (a) Inhibiting synthesis of N-acetyl muramic acid pentapeptide (b) Inhibiting conjugation between N-acetyl muramic acid and N-acetyl ... link the peptidoglycan residues (d) Counterfeiting for D-alanine in the bacterial cell wall

Last Answer : Ans: C

Description : All of the following drugs are suitable oral therapy for a lower urinary tract infection due to Pseudomonas aeruginosa except (a) Norfloxacin (b) Trimethoprim-sulfamethxazole (c) Ciprofloxacin (d) Carbenicillin (e) Methenamine mandelate

Last Answer : Ans: B

Description : All of the following factors may increase the risk of nephrotoxicity from gentamicin therapy except (a) age over 70 years (b) prolonged courses of gentamicin therapy (c) concurrent amphotericin B therapy (d) trough gentamicin levels below 2 mg/ml (e) concurrent cisplatin therapy

Last Answer : Ans: D

Description : Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellular(MAI)? (a) Vancomycin (b) Clarithromycin (c) Erythromycin base (d) Troleandomycin (e) Erythromycin estolate

Last Answer : Ans: B