Description : Piperacillin differs from carbenicillin in the following respect(s): A. It is more active against Pseudomonas aeruginosa B. It is active against Klebsiella as well C. It is acid resistant D. Both ‘A’ and ‘B’ are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : All of the following drugs are suitable oral therapy for a lower urinary tract infection due to Pseudomonas aeruginosa except (a) Norfloxacin (b) Trimethoprim-sulfamethxazole (c) Ciprofloxacin (d) Carbenicillin (e) Methenamine mandelate
Last Answer : Ans: B
Description : Cefotaxime has the following properties except (a) It is highly active against aerobic gram negative bacteria (b) It is the most active cephalosporin against Pseudomonas aeruginosa (c) It produces an active metabolite (d) It has achieved high cure rates in serious hospital acquired infections
Description : This drug has activity against many strains of Pseudomomas aeruginosa. However, when it is used alone, resistance has emerged during the course of treatment. The drug should not be used in ... with tazobactam (a) Amoxicillin (b) Aztreonam (c) Imipenem (d) Piperacillin (e) Vancomycin
Last Answer : Ans: D
Description : Beta - lactamase production by strains of Haemophilus influenzae, Moraxella catarrhalis, and Neissera gonorrhoeae confers resistance against penicillin G.which one of the following antibiotics is most likely to be ... ? (a) Ampicillin (b) Ceftriaxone (c) Clindamycin (d) Gentamicin (e) Piperacillin
Description : Amoxicillin + Clavulanic acid is active against the following organism except (a) Methicillin resistant Staph. aureus (b) Penicillinase producing Staph. aureus (c) Penicillinase producing n. gonorrhoeae (d) ß-lactamase producing E. coli
Last Answer : Ans: A
Description : Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it (a) Eradicates mycoplasmal infections in a single dose (b ... not inhibit live drug-metabolizing enzymes (e) Acts on methicillin-resistant strains of staphylococci
Last Answer : Ans: C
Description : Which of the following is not a semisynthetic penicillin ? (a) Procaine penicillin (b) Ampicillin (c) Cloxacillin (d) Carbenicillin
Description : Tetracyclines are active against the following gram negative bacteria: A. Salmonella typhi B. Pseudomonas aeruginosa C. Yersinia pestis D. All of the above
Last Answer : C. Yersinia pestis
Description : Cefotaxime has the following properties except: A. It is highly active against aerobic gram negative bacteria B. It is the most active cephalosporin against Pseudomonas aeruginosa C. It produces an active metabolite D. It has achieved high cure rates in serious hospital acquired infections
Last Answer : B. It is the most active cephalosporin against Pseudomonas aeruginosa
Description : The β-lactam antibiotic(s) that prolong(s) bleeding time by altering surface receptors on platelets is/are: A. Carbenicillin B. Piperacillin C. Cefotaxime D. Both `A’ and `B’ are correct
Last Answer : A. Carbenicillin
Description : Which one of the following drugs is most likely to be effective against multidrug – resistant strains of M tuberculosis, including those resistant to streptomycin? (a) Amikacin (b) Clarithromycin (c) Gentamicin (d) Meropenem (e) Spectinomycin
Description : Choose the semisynthetic penicillin which has an extended spectrum of activity against many gram negative bacilli, is acid resistant but not penicillinase resistant: A. Cloxacillin B. Amoxicillin C. Phenoxymethyl penicillin D. Piperacillin
Last Answer : B. Amoxicillin
Description : Aminoglycoside antibiotics have the following common property (a) They are primarily active against gramnegative bacilli (b) They are more active in acidic medium (c) They readily enter cells and are distributed in total body water (d) They are nearly completely metabolized in liver
Description : Chloramphenicol is more active than tetracyclines against (a) Bateroides fragilis (b) Treponema pallidum (c) Streptococci (d) Staphylococci
Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic ... (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well
Description : Which one of the following statements about cefotetan is accurate? (a) It is active against MRSA strains (b) It is the drug of choice in community-acquired pneumonia (c) ... fourth-generation cephalosporin (d) It decreases prothrombin time (e) Its antibacterial spectrum include Bacteroides fragilis
Last Answer : Ans: E
Description : The drug of choice for treatment of methicillin resistant Staphylococcus aureus infection is (a) Cloxacillin (b) Vancomycin (c) Erythromycin (d) Amikacin
Description : What is break point concentration of an antibiotic ? (a) Concentration at which the antibiotic lyses the bacteria (b) Concentration of the antibiotic which demarks between sensitive ... which overcomes bacterial resistance (d) Concentration at which a bacteriostatic antibiotic becomes bactericidal
Description : Methicillin resistant staphylococci do not respond to ß-lactam antibiotics because (a) They produce a ß-lactamase which destroys methicillin and related drugs (b) They elaborate an amidase which destroys ... low affinity for ß-lactam antibiotics (d) They are less permeable to ß-lactam antibiotics
Description : Widespread and prolonged used of an antibiotic leads to emergence of drug resistant strains because antibiotics (a) Induce mutation in the bacteria (b) Promote conjugation among bacteria (c) Allow resistant strains to propagate preferentially (d) All of the above
Description : Spectinomycin is an aminoglycoside-like antibiotic indicated for the treatment of (a) Gram-negative bacillary septicemia (b) Tuberculosis (c) Penicillin-resistant gonococcal infections (d) Syphilis (e) Gram-negative meningitis due to susceptible organisms
Description : Select the semisynthetic penicillin which is not acid resistant: A. Phenoxymethyl penicillin B. Ampicillin C. Carbenicillin D. Cloxacillin
Last Answer : C. Carbenicillin
Description : : All the following are among the opportunistic organisms that may cause nosocomial disease except: a. Pseudomonas aeruginosa. b. Escherichia coli. c. Staphylococcus aureus. d. Mycobacterium leprae.
Last Answer : d. Mycobacterium leprae.
Description : The most common cause of an invasive wound infection, such as a burn, is a. gram-positive bacterial species. b. treponema pallidum. c. Pseudomonas aeruginosa. d. Escherichia coli.
Last Answer : c. Pseudomonas aeruginosa.
Description : What bacterial species is most often associated with cystitis? a. Treponemo pallidum b. Escherichia coIi c. Chlamydia trachomatis d. Pseudomonas aeruginosa
Last Answer : b. Escherichia coIi
Description : Pseudomonas aeruginosa forms a blue water soluble pigment called A-pyocyanin B- chlororaphin C- pyoverdin D-β-carotene
Last Answer : pyocyanin
Description : Which of the following bacteria dies quickly after drying? A- .Treponema palladium B- Mycobacterium tuberculosis C- Staphylococcus aureus D- Pseudomonas aeruginosa
Last Answer : .Treponema palladium
Description : The following organisms are frequently responsible for superinfections except: A. Pseudomonas aeruginosa B. Salmonella typhi C. Clostridium difficile D. Candida albicans
Last Answer : B. Salmonella typhi
Description : In the empiric treatment of severe bacterial infections of unidentified entiology, this drug, often used in combination with an aminoglycoside, provides coverage against many staphylococci (a) Amoxicillin (b) Clavulanic acid (c) Erythromycin (d) Nafcillin (e) Tetracycline
Description : Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellular(MAI)? (a) Vancomycin (b) Clarithromycin (c) Erythromycin base (d) Troleandomycin (e) Erythromycin estolate
Description : Which fluoroquinolone has markedly enhanced activity against gram positive bacteria and anaerobes ? (a) Pefloxacin (b) Ciprofloxacin (c) Sparfloxacin (d) Norfloxacin
Description : Do anti-vaxxers also eschew things like tetanus shots and antibiotics?
Last Answer : Some do I am sure. I am anti- OVER vaccinating, and this is why I won't be re-vaccinating my 7 and 10 yr. old cats that are indoors only at this time. They have enough immunity ... horses. Horses are highly susceptible to Tetanus, more so than other farm animals, though they are vaccinated as well.
Description : Streptomycin sulfate is not absorbed orally because it is (a) Degraded by gastrointestinal enzymes (b) Destroyed by gastric acid (c) Highly ionized at a wide range of pH values (d) Insoluble in water
Description : Clavulanic acid is combined with amoxicillin because (a) It kills bacteria that are not killed by-moxicillin (b) It reduces renal clearance of amoxicillin (c) It counteracts the adverse effects of amoxicillin (d) It inhibits beta lactamases that destroy amoxicillin
Description : Penicillins interfere with bacterial cell wall synthesis by (a) Inhibiting synthesis of N-acetyl muramic acid pentapeptide (b) Inhibiting conjugation between N-acetyl muramic acid and N-acetyl ... link the peptidoglycan residues (d) Counterfeiting for D-alanine in the bacterial cell wall
Description : A 36-year-old woman recently treated for leukemia is admitted to hospital with malaise, chills and high fever. Gram stain of blood reveals the presence of gramnegative bacilli. The initial diagnosis is ... (b) Aztreonam (c) Cefazolin (d) Imipenem plus cilastatin (e) Ticarcillin plus clavulanic acid
Description : Gentamicin differs from streptomycin in that: A. It is less nephrotoxic B. It is used for pseudomonas infections C. It is not effective in tuberculosis D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Cloxacillin is indicated in infections caused by the following organism(s) (a) Staphylococci (b) Streptococci (c) Gonococci (d) All of the above
Description : In the treatment of typhoid fever, ciprofloxacin has the following advantage(s) (a) It is effective in nearly all cases (b) Early abetment of fever and other symptoms (c) Development of carrier state is less likely (d) All of the above
Description : Superinfections are more common with (a) Use of narrow spectrum antibiotics (b) Short courses of antibiotics (c) Use of antibiotics that are completely absorbed from the small intestines (d) Use of antibiotic combinations covering both gram positive and gram negative bacteria
Description : Select the sulfonamide drug which is active against Pseudomonas and is used by topical application for prophylaxis of infection in burn cases: A. Sulfadiazine B. Silver sulfadiazine C. Sulfadoxine D. Sulfamethoxazole
Last Answer : B. Silver sulfadiazine
Description : Gram negative organisms are largely insensitive to benzyl penicillin because (a) They produce large quantities of penicillinase (b) They do not utilize D-alanine whose incorporation in the cell wall is ... lipoprotein-peptidoglycan multiplayer cell wall of gram-negative bacteria (d) Both (a) and (b)
Description : An advantage of bleomycin over most antineoplastic drugs is its (a) Rapid onset of action (b) Lack of toxicity to all normal cells (c) Relative lack of bone marrow toxicity (d) Very broad spectrum of activity (e) Both (a) and (b)
Description : Choose the correct statement(s) about cefepime: A. It is a 4th generation cephalosporin B. It is active against many bacteria resistant to 3rd generation celphalosporins C. It is active by the oral route D. Both 'A' and 'B' are correct
Last Answer : D. Both 'A' and 'B' are correct
Description : Roxithromycin has the following advantages over erythromycin except (a) It is more effective in whooping cough (b) It causes less gastric irritation (c) It has longer plasma half-life (d) It is unlikely to precipitate theophylline toxicity
Description : Which aminoglycoside antibiotic causes more hearing loss than vestibular disturabance as toxic effect ? (a) Streptomycin (b) Gentamicin (c) Kanamycin (d) Sisomicin
Description : Benzathine penicillin injected once every 4 weeks for 5 years or more is the drug of choice for (a) Agranulocytosis patients (b) Prophylaxis of bacterial endocarditis in patients with valvular defects (c) Prophylaxis of rheumatic fever (d) Treatment of anthrax
Description : Which of the following is not true of sulfonamides ? (a) They are primarily metabolized by acetylation (b) They are more likely to produce crystalluria in alkaline urine in which they are ... in the urinary tract (d) Used alone, they have become therapeutically unreliable for serious infections
Description : An advantge of betamethasone acetate over betamethasone sodium phosphate is (a) Fewer allergic reactions (b) Prompter action (c) More sustained action (d) Greater solubility (e) There is no advantage