Acetyl salicylic acid is soluble in (a) An aqueous base (b) Water (c) An aqueous acid

Acetyl salicylic acid is soluble in (a) An aqueous base (b) Water (c) An aqueous acid
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Ans: A
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Decomposition of the acetyl salicylic acid at room temperature most likely would occur by (a) Oxidation of the ester (b) Reduction of the carboxylic acid (c) Hydrolysis of the ester

Description : Decomposition of the acetyl salicylic acid at room temperature most likely would occur by (a) Oxidation of the ester (b) Reduction of the carboxylic acid (c) Hydrolysis of the ester

Last Answer : Ans: C

Opioid analgesics are either contraindicated or must be used with extreme caution in several clinical situations. For morphine, such situations do not include (a) Aqueous diffusion (b) Aqueous hydrolysis (c) Lipid diffusion (d) Pinocytosis or endocytosis (e) Special carrier transport

Description : Opioid analgesics are either contraindicated or must be used with extreme caution in several clinical situations. For morphine, such situations do not include (a) Aqueous diffusion (b) Aqueous hydrolysis (c) Lipid diffusion (d) Pinocytosis or endocytosis (e) Special carrier transport

Last Answer : Ans: E

In the treatment of chronic inflammatory diseases, the most important limitation of aspirin is (a) Acid – base and electrolytc disturbances (b) Hypersensitivity and idiosyncratic reactions (c) Gastric mucosal damage (d) Salicylism

Description : In the treatment of chronic inflammatory diseases, the most important limitation of aspirin is (a) Acid – base and electrolytc disturbances (b) Hypersensitivity and idiosyncratic reactions (c) Gastric mucosal damage (d) Salicylism

Last Answer : Ans: C

The termination of heparin activity by protamine sulfate is due to (a) A chelating action (b) The inhibition of gastrointestinal absorption of heparin (c) The displacement of heparin-plasma protein binding (d) An acid-base interaction (e) The prothrombin-like activity of protamine

Description : The termination of heparin activity by protamine sulfate is due to (a) A chelating action (b) The inhibition of gastrointestinal absorption of heparin (c) The displacement of heparin-plasma protein binding (d) An acid-base interaction (e) The prothrombin-like activity of protamine

Last Answer : Ans: D

Acetyl salicylic acid is 1. Used as a tear gas 2. Aspirin 3. A pain killer 4. A sedative The correct answers are: (a) 1 and 4 (b) 1 and 2 (c) 2 and 3 (d) 2 and 4

Description : Acetyl salicylic acid is 1. Used as a tear gas 2. Aspirin 3. A pain killer 4. A sedative The correct answers are: (a) 1 and 4 (b) 1 and 2 (c) 2 and 3 (d) 2 and 4

Last Answer : Ans:(c)

Chemically aspirin is (a) phenol (b) salicylic acid (c) acetyl salicylic acid (d) benzoic acid

Description : Chemically aspirin is (a) phenol (b) salicylic acid (c) acetyl salicylic acid (d) benzoic acid

Last Answer : Ans:(c)

Aspirin is common name of – (1) Salicylic Acid (2) Salicylate (3) Methyl Salicylate (4) Acetyl Salicylic Acid

Description : Aspirin is common name of – (1) Salicylic Acid (2) Salicylate (3) Methyl Salicylate (4) Acetyl Salicylic Acid

Last Answer : (4) Acetyl Salicylic Acid Explanation: Aspirin (USAN), also known as acetylsalicylic acid, is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an ... under normal circumstances binds platelet molecules together to create a patch over damaged walls of blood vessels.

Acetyl salicylic acid is commonly used as which medicine?

Description : Acetyl salicylic acid is commonly used as which medicine?

Last Answer : A pain killer

What is the common name for the drug acetyl salicylic acid? A. Paracetamol B. Analgin C. Aspirin (Answer) D. Penicillin

Description : What is the common name for the drug acetyl salicylic acid? A. Paracetamol B. Analgin C. Aspirin (Answer) D. Penicillin

Last Answer : C. Aspirin (Answer)

When taking Mono Amino Oxidase Inhibitors (MAOI); which drugs are contra indicated: I. Barbiturate II. Local anaesthetic III. Pethidine IV. Acetyl salicylic acid A. All of the above B. None of the above C. I, II and III D. II, III and IV

Description : When taking Mono Amino Oxidase Inhibitors (MAOI); which drugs are contra indicated: I. Barbiturate II. Local anaesthetic III. Pethidine IV. Acetyl salicylic acid A. All of the above B. None of the above C. I, II and III D. II, III and IV

Last Answer : C. I, II and III

Aspirin is common name of (1) Salicylic Acid (2) Salicylate (3) Methyl Salicylate (4) Acetyl Salicylic Acid

Description : Aspirin is common name of (1) Salicylic Acid (2) Salicylate (3) Methyl Salicylate (4) Acetyl Salicylic Acid

Last Answer : Acetyl Salicylic Acid

Why is CuSO4 more soluble in water than in an organic solvent and why is the reverse true salicylic acid?

Description : Why is CuSO4 more soluble in water than in an organic solvent and why is the reverse true salicylic acid?

Last Answer : Water and copper sulfate are both polar compound; polar compounds are dissolved better in polar solvents. Salycilic acid is also polar but the solubility is lower because the benzene ring has a negative effect.

The action of aspirin that results in its greater efficacy as an antithrombotic (anti-platelet) drug is its ability to (a) Inhibit lipoxygenase as well as cyclooxygenase (b) Selectively inhibit cyclooxygenase I (c) Inhibit leukocyte migration (d) Promote uric acid excretion (e) Acetylate cyclooxygenase

Description : The action of aspirin that results in its greater efficacy as an antithrombotic (anti-platelet) drug is its ability to (a) Inhibit lipoxygenase as well as cyclooxygenase (b) Selectively inhibit ... I (c) Inhibit leukocyte migration (d) Promote uric acid excretion (e) Acetylate cyclooxygenase

Last Answer : Ans: E

Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in inflammatory processes are produced from arachidonic acid by (a) Cyclooxygenase 1 (b) Cyclooxygenase 2 (c) Glutathione – S – transferase (d) Lipoxygenase (e) Phospholipase A2

Description : Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in inflammatory processes are produced from arachidonic acid by (a) ... 2 (c) Glutathione - S - transferase (d) Lipoxygenase (e) Phospholipase A2

Last Answer : Ans: B

For limiting cerebral edema due to brain tumour, the preferred corticosteroids are betamenthasone/dexamethasone because (a) They do not cause Na+ and water retention (b) They are more potent (c) They can be administered intravenously (d) They inhibit brain tumours

Description : For limiting cerebral edema due to brain tumour, the preferred corticosteroids are betamenthasone/dexamethasone because (a) They do not cause Na+ and water retention (b) They are more potent (c) They can be administered intravenously (d) They inhibit brain tumours

Last Answer : Ans: A

Generally the earliest manifestation of salicylism is (a) Visual disturbance (b) Excitement (c) Hyperventillation (d) Tinnitus

Description : Generally the earliest manifestation of salicylism is (a) Visual disturbance (b) Excitement (c) Hyperventillation (d) Tinnitus

Last Answer : Ans: D

Aspirin reduces fever by (a) Decreasing heat production in the body (b) Enhancing cutaneous blood flow (c) Inducing sweating (d) Both (b) and (c)

Description : Aspirin reduces fever by (a) Decreasing heat production in the body (b) Enhancing cutaneous blood flow (c) Inducing sweating (d) Both (b) and (c)

Last Answer : Ans: D

Aspirin produces analgesia by (a) Preventing sensitization of peripheral pain receptors (b) Affecting gating of pain impulses at spinal level (c) Raising pain threshold at subcortical level (d) Both (a) and (b)

Description : Aspirin produces analgesia by (a) Preventing sensitization of peripheral pain receptors (b) Affecting gating of pain impulses at spinal level (c) Raising pain threshold at subcortical level (d) Both (a) and (b)

Last Answer : Ans: D

The distinctive feature of the isoenzyme cyclooxygenase-2 is (a) It is not inhibited by indomethacin (b) It is inducible (c) It generates cytoprotective prostagladins in gastric mucosa (d) It is found only in foetal tissues

Description : The distinctive feature of the isoenzyme cyclooxygenase-2 is (a) It is not inhibited by indomethacin (b) It is inducible (c) It generates cytoprotective prostagladins in gastric mucosa (d) It is found only in foetal tissues

Last Answer : Ans: B

Following mediators are involved in acute inflammation except (a) Histamine (b) Leukotrienes (c) Interferons (d) Bradykinin

Description : Following mediators are involved in acute inflammation except (a) Histamine (b) Leukotrienes (c) Interferons (d) Bradykinin

Last Answer : Ans: C

Lower dose of naloxone is required to (a) Antagonise the actions of nalorphine (b) Antagonise the actions of pentazocine (c) Precipitate withdrawal in mildly morphine dependent subjects (d) Precipitate withdrawal in highly morphine dependent subjects

Description : Lower dose of naloxone is required to (a) Antagonise the actions of nalorphine (b) Antagonise the actions of pentazocine (c) Precipitate withdrawal in mildly morphine dependent subjects (d) Precipitate withdrawal in highly morphine dependent subjects

Last Answer : Ans: D

Which action of morphine is incompletely reversed by naloxone ? (a) Analgesia (b) Respiratory depression (c) Sedation (d) Miosis

Description : Which action of morphine is incompletely reversed by naloxone ? (a) Analgesia (b) Respiratory depression (c) Sedation (d) Miosis

Last Answer : Ans: C

Pentazocine differs from morphine in that (a) It is inactive by the oral route (b) It does not produce physical dependence (c) It has a lower ceiling of analgesic effect (d) Its action is not blocked by naloxone

Description : Pentazocine differs from morphine in that (a) It is inactive by the oral route (b) It does not produce physical dependence (c) It has a lower ceiling of analgesic effect (d) Its action is not blocked by naloxone

Last Answer : Ans: C

Which of the following is an agonistantagonist type of opioid analgesic (a) Pethidine (b) Pentazocine (c) Fentanyl (d) Buprenorphine

Description : Which of the following is an agonistantagonist type of opioid analgesic (a) Pethidine (b) Pentazocine (c) Fentanyl (d) Buprenorphine

Last Answer : Ans: B

Morphine has high affinity for the following opioid receptor(s). (a) µ (Mu) (b) k (Kappa) (c) d (Delta) (d) All of the above

Description : Morphine has high affinity for the following opioid receptor(s). (a) µ (Mu) (b) k (Kappa) (c) d (Delta) (d) All of the above

Last Answer : Ans: A

An opioid analgesic is preferred over aspirin like analgesic in the following condition. (a) Acute gout (b) Burn (c) Toothache (d) Neuralgia

Description : An opioid analgesic is preferred over aspirin like analgesic in the following condition. (a) Acute gout (b) Burn (c) Toothache (d) Neuralgia

Last Answer : Ans: B

Select the analgesic which acts through opioids as well as additional spinal monoaminergic mechanisms. (a) Tramadol (b) Ethoheptazine (c) Dextropropoxyphene (d) Alfentanil

Description : Select the analgesic which acts through opioids as well as additional spinal monoaminergic mechanisms. (a) Tramadol (b) Ethoheptazine (c) Dextropropoxyphene (d) Alfentanil

Last Answer : Ans: A

Which of the following opioid analgesics is similar to codeine in pharmacological profile but is less constipating ? (a) Methadone (b) Buprenorphine (c) Butorphanol (d) Dextropropoxyphene

Description : Which of the following opioid analgesics is similar to codeine in pharmacological profile but is less constipating ? (a) Methadone (b) Buprenorphine (c) Butorphanol (d) Dextropropoxyphene

Last Answer : Ans: D

Which of the following opioids is more potent than morphine ? (a) Pethidine (b) Fentanyl (c) Dextropropoxyphene (d) Tramadol

Description : Which of the following opioids is more potent than morphine ? (a) Pethidine (b) Fentanyl (c) Dextropropoxyphene (d) Tramadol

Last Answer : Ans: B

Morphine is contraindicated in head injury because (a) It does not relieve the pain of head injury (b) It can raise intracranial tension (c) It can cause constipation (d) It is liable to cause addiction

Description : Morphine is contraindicated in head injury because (a) It does not relieve the pain of head injury (b) It can raise intracranial tension (c) It can cause constipation (d) It is liable to cause addiction

Last Answer : Ans: B

Morphine dependence is characterized by (a) Marked drug seeking behavior (b) Physical dependence without psychic dependence (c) Physical as well as psychic dependence (d) Both (a) and (c)

Description : Morphine dependence is characterized by (a) Marked drug seeking behavior (b) Physical dependence without psychic dependence (c) Physical as well as psychic dependence (d) Both (a) and (c)

Last Answer : Ans: D

Instead of being effective in hyperuricaemia following drug is contradictred in the treatment of gout (a) Indomethacin (b) Diclofenac (c) Piroxicam (d) Aspirin

Description : Instead of being effective in hyperuricaemia following drug is contradictred in the treatment of gout (a) Indomethacin (b) Diclofenac (c) Piroxicam (d) Aspirin

Last Answer : Ans: D

In a comatose patient suspected of poisoning, which of the following findings would be against the drug being morphine (a) Selegiline (b) Chlorgiline (c) Moclobemide (d) Tranylcypromine

Description : In a comatose patient suspected of poisoning, which of the following findings would be against the drug being morphine (a) Selegiline (b) Chlorgiline (c) Moclobemide (d) Tranylcypromine

Last Answer : Ans: A

Instead of depressing, morphine stimulates (a) Vasomotor centre (b) Edinger westphal nucleus (c) Temperature regulating centre (d) Cough centre

Description : Instead of depressing, morphine stimulates (a) Vasomotor centre (b) Edinger westphal nucleus (c) Temperature regulating centre (d) Cough centre

Last Answer : Ans: B

In man sedation caused by morphine is characterized by (a) Initial excitement (b) Little or no motor incoordination (c) Rise in seizure threshold (d) All of the above

Description : In man sedation caused by morphine is characterized by (a) Initial excitement (b) Little or no motor incoordination (c) Rise in seizure threshold (d) All of the above

Last Answer : Ans: B

Morphine produces analgesia by acting at (a) Peripheral pain receptors (b) A spinal site (c) Suspraspinal sites (d) Both (b) and (c)

Description : Morphine produces analgesia by acting at (a) Peripheral pain receptors (b) A spinal site (c) Suspraspinal sites (d) Both (b) and (c)

Last Answer : Ans: B

Which of the following bones is affected more by glucocorticoid induced osteoporosis? (a) Femur (b) Humerus (c) Radius (d) Lumber vertebra

Description : Which of the following bones is affected more by glucocorticoid induced osteoporosis? (a) Femur (b) Humerus (c) Radius (d) Lumber vertebra

Last Answer : Ans: D

The following adverse effect of corticosteroids is due to their mineralocorticoid action (a) Osteoporosis (b) Rise in blood pressure (c) Moon face (d) Increased susceptibility to infection

Description : The following adverse effect of corticosteroids is due to their mineralocorticoid action (a) Osteoporosis (b) Rise in blood pressure (c) Moon face (d) Increased susceptibility to infection

Last Answer : Ans: B

Systemic corticosteroid therapy is not used routinely and is reserved only for severe cases of (a) Exfoliative dermatitis (b) Posterior uveitis (c) Acute rheumatic fever (d) Hodgkin’s disease

Description : Systemic corticosteroid therapy is not used routinely and is reserved only for severe cases of (a) Exfoliative dermatitis (b) Posterior uveitis (c) Acute rheumatic fever (d) Hodgkin’s disease

Last Answer : Ans: C

Corticosteroid therapy is practically mandatory in the following condition. (a) Septic shock (b) Renal transplant (c) Rheumatoid arthritis (d) Ulcerative colitis

Description : Corticosteroid therapy is practically mandatory in the following condition. (a) Septic shock (b) Renal transplant (c) Rheumatoid arthritis (d) Ulcerative colitis

Last Answer : Ans: B

Which of the following glucocorticoids has significant mineralocorticoid activity also ? (a) Hydrocortisone (b) Triamcinolone (c) Dexamethasone (d) Betamethasone

Description : Which of the following glucocorticoids has significant mineralocorticoid activity also ? (a) Hydrocortisone (b) Triamcinolone (c) Dexamethasone (d) Betamethasone

Last Answer : Ans: A

Main effect of sulphinpyrazone in hyperuricaemia is (a) Suppress the symptoms (b) Promote the elimination of urate (c) prevent urate synthesis (d) All of the above

Description : Main effect of sulphinpyrazone in hyperuricaemia is (a) Suppress the symptoms (b) Promote the elimination of urate (c) prevent urate synthesis (d) All of the above

Last Answer : Ans: B

Corticosteroids exert anti-inflammatory action by inhibiting the following enzyme (a) Cycloxygenase (b) Lipozygenase (c) Phospholipase - A (d) Phosphodiesterase

Description : Corticosteroids exert anti-inflammatory action by inhibiting the following enzyme (a) Cycloxygenase (b) Lipozygenase (c) Phospholipase - A (d) Phosphodiesterase

Last Answer : Ans: C

Cervical priming with prostaglandin results in (a) Facilitation of sperm movement through cervical canal (b) Increased cervical tone (c) Softening of cervix (d) Increased cervical secretions

Description : Cervical priming with prostaglandin results in (a) Facilitation of sperm movement through cervical canal (b) Increased cervical tone (c) Softening of cervix (d) Increased cervical secretions

Last Answer : Ans: C

The early pregnancy uterus is sensitive to the following oxytocic (a) Oxytocin (b) Methylergometrine (c) Prostaglandin F2a (d) Both (a) and (b)

Description : The early pregnancy uterus is sensitive to the following oxytocic (a) Oxytocin (b) Methylergometrine (c) Prostaglandin F2a (d) Both (a) and (b)

Last Answer : Ans: C

Aspirin in low doses produces longlasting inhibition (a) Platelets contain low quantity of COX (b) Platelets cannot synthesize fresh COX molecules (c) Platelets bind aspirin with high affinity (d) Platelet COX is inducible

Description : Aspirin in low doses produces longlasting inhibition (a) Platelets contain low quantity of COX (b) Platelets cannot synthesize fresh COX molecules (c) Platelets bind aspirin with high affinity (d) Platelet COX is inducible

Last Answer : Ans: B

The following prostanoid is a potent inducer of platelet aggregation (a) Prostacyclin (b) Prostaglandin E2 (c) Prostaglandin D2 (d) Thromboxane A2

Description : The following prostanoid is a potent inducer of platelet aggregation (a) Prostacyclin (b) Prostaglandin E2 (c) Prostaglandin D2 (d) Thromboxane A2

Last Answer : Ans: D

The prostanoid that consistently constricts blood vessels is (a) Prostaglandin E2 (b) Prostaglandin F2a (c) Thromboxane A2 (d) Prostacyclin

Description : The prostanoid that consistently constricts blood vessels is (a) Prostaglandin E2 (b) Prostaglandin F2a (c) Thromboxane A2 (d) Prostacyclin

Last Answer : Ans: C

Which of the following is an irreversible inhibitor of cyclooxygenase ? (a) Aspirin (b) Phenylbutazone (c) Indomethacin (d) Piroxicam

Description : Which of the following is an irreversible inhibitor of cyclooxygenase ? (a) Aspirin (b) Phenylbutazone (c) Indomethacin (d) Piroxicam

Last Answer : Ans: A

The cyclooxygenase isoenzymes COX-1 and COX-2 differ from each other in that (a) They catalyse different pathways in prostanoid biosynthesis (b) COX–1 is inhibited by aspirin but not COX–2 (c) COX–2 is inhibited by ibuprofen but not COX–1 (d) COX–1 is constitutive while COX–2 is inducible

Description : The cyclooxygenase isoenzymes COX-1 and COX-2 differ from each other in that (a) They catalyse different pathways in prostanoid biosynthesis (b) COX–1 is inhibited by aspirin but not COX–2 (c) COX–2 is inhibited by ibuprofen but not COX–1 (d) COX–1 is constitutive while COX–2 is inducible

Last Answer : Ans: D