Glucose uptake by liver cells is (A) Energy-consuming (B) A saturable process (C) Insulin-dependent (D) Insulin-independent

Glucose uptake by liver cells is (A) Energy-consuming (B) A saturable process (C) Insulin-dependent (D) Insulin-independent
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Insulin is required for the active uptake of glucose by most of the cells except (A) Muscle cells (B) Renal tubular cells (C) Adipocytes (D) Liver cells

Description : Insulin is required for the active uptake of glucose by most of the cells except (A) Muscle cells (B) Renal tubular cells (C) Adipocytes (D) Liver cells

Last Answer : Answer : D

A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the following? a. Increased glucose uptake and increased glycogen breakdown occur in this circumstance. b. Suppressed activity of lipoprotein lipase results from TNFa c. TNFa stimulates lipolysis d. The differentiation process of pre-adipocytes is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs

Description : A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the ... is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs

Last Answer : Answer: a, b, c, d, e Tumor cachexia appears to be mediated by TNFa. Lipopolysaccharide (LPS), as well as other cytokines, activate a variety of inflammatory cells, most ... chronic syndromes of anorexia, weight loss, and cachexia that are associated with both chronic infection and malignancy

Glucose enters the cells by (A) insulin independent transport (B) insulin dependent transport (C) enzyme mediated transport (D) Both (A) and (B)

Description : Glucose enters the cells by (A) insulin independent transport (B) insulin dependent transport (C) enzyme mediated transport (D) Both (A) and (B)

Last Answer : D

What is the effect of insulin on glucose uptake of cells?

Description : What is the effect of insulin on glucose uptake of cells?

Last Answer : Insulin facilitates the membrane transport of glucose in most of tissues, especially in muscles and adipose tissue. This is by glucose transporter, GIuT4. But glucose uptake by GlT2 is independent of insulin, it is seen in liver and brain.

Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct

Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct

Last Answer : D. Both A and B are correct

Glucose entry into the cells of the following organ/ tissue is highly dependent on the presence of insulin: A. Brain B. Liver C. Adipose tissue D. Kidney tubules

Description : Glucose entry into the cells of the following organ/ tissue is highly dependent on the presence of insulin: A. Brain B. Liver C. Adipose tissue D. Kidney tubules

Last Answer : C. Adipose tissue

Deficiency of insulin results in (A) Rapid uptake of sugar (B) Low blood glucose level (C) Decrease urine output (D) Presence of glucose in urine

Description : Deficiency of insulin results in (A) Rapid uptake of sugar (B) Low blood glucose level (C) Decrease urine output (D) Presence of glucose in urine

Last Answer : Answer : D

Regarding retinal metabolism: a. insulin is essential for the uptake of glucose by the retina b. anaerobic metabolism predominates c. the pigment retinal epithelium stores glycogen and supplies the need of the retina d. the demand of oxygen is met entirely by the central retinal artery

Description : Regarding retinal metabolism: a. insulin is essential for the uptake of glucose by the retina b. anaerobic metabolism predominates c. the pigment retinal epithelium stores glycogen and supplies the need of the retina d. the demand of oxygen is met entirely by the central retinal artery

Last Answer : anaerobic metabolism predominates

Insulin: a. is secreted as a pro-insulin b. increases protein synthesis c. is required for glucose uptake in all tissues d. is a steroid hormone

Description : Insulin: a. is secreted as a pro-insulin b. increases protein synthesis c. is required for glucose uptake in all tissues d. is a steroid hormone

Last Answer : is secreted as a pro-insulin

Which of the following represents the action of insulin? (a) Increases blood glucose level by stimulating glucagon production. (b) Decreases blood glucose levels by forming glycogen. (c) Increases blood glucose levels by promoting cellular uptake of glucose. (d) Increases blood glucose levels by hydrolysis of glycogen.

Description : Which of the following represents the action of insulin? (a) Increases blood glucose level by stimulating glucagon production. (b) Decreases blood glucose levels by forming glycogen. (c) ... promoting cellular uptake of glucose. (d) Increases blood glucose levels by hydrolysis of glycogen.

Last Answer : (b) Decreases blood glucose levels by forming glycogen

Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilisation. (a) Insulin (b) Glucagon (c) Secretin (d) Gastrin

Description : Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilisation. (a) Insulin (b) Glucagon (c) Secretin (d) Gastrin

Last Answer : (a) Insulin

Active transport of a substance across biological membranes has the following characteristics except: A. It is specific B. It is pH dependent C. It is saturable D. It requires metabolic energy

Description : Active transport of a substance across biological membranes has the following characteristics except: A. It is specific B. It is pH dependent C. It is saturable D. It requires metabolic energy

Last Answer : B. It is pH dependent

Active transport of a substance across biological membranes has the following characteristics except: A. It is specific B. It is pH dependent C. It is saturable D. It requires metabolic energy

Description : Active transport of a substance across biological membranes has the following characteristics except: A. It is specific B. It is pH dependent C. It is saturable D. It requires metabolic energy

Last Answer : B. It is pH dependent

A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of diabetic ketoacidosis: 1) Abdominal pain at onset 2) A serum bicarbonate of 10 mmol/l 3) A serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations

Description : A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of ... serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations

Last Answer : Answers-2 a-An unusual but recognised feature particularly in children. However does not support a diagnosis of DKA. b-Suggests metabolic acidosis. c-'Normoglycaemic DKA' can occur and a glucose ... anorexia. e-Respiratory compensation leads to rapid deep (Kussmaul's) breathing. (Dr Mike Mulcahy)

Action of Insulin does not include the following: A. Facilitation of glucose transport into cells B. Facilitation of glycogen synthesis by liver C. Facilitation of neoglucogenesis by liver D. Inhibition of lipolysis in adipose tissue

Description : Action of Insulin does not include the following: A. Facilitation of glucose transport into cells B. Facilitation of glycogen synthesis by liver C. Facilitation of neoglucogenesis by liver D. Inhibition of lipolysis in adipose tissue

Last Answer : . Facilitation of neoglucogenesis by liver

Sodium is involved in the active uptake of (A) D-Glucose (B) D-Galactose (C) L-Amino acids (D) All of these

Description : Sodium is involved in the active uptake of (A) D-Glucose (B) D-Galactose (C) L-Amino acids (D) All of these

Last Answer : Answer : D

Cori cycle is (A) Synthesis of glucose (B) reuse of glucose (C) uptake of glycose (D) Both (A) & (B)

Description : Cori cycle is (A) Synthesis of glucose (B) reuse of glucose (C) uptake of glycose (D) Both (A) & (B)

Last Answer : D

Active uptake of glucose is inhibited by (A) Ouabain (B) Phlorrizin (C) Digoxin (D) Alloxan

Description : Active uptake of glucose is inhibited by (A) Ouabain (B) Phlorrizin (C) Digoxin (D) Alloxan

Last Answer : B

Which of the following glucose transporters is insulin-dependent? (a) GLUT IV (b) GLUT I (c) GLUT II (d) GLUT III

Description : Which of the following glucose transporters is insulin-dependent? (a) GLUT IV (b) GLUT I (c) GLUT II (d) GLUT III

Last Answer : (a) GLUT IV

Which of the following clinical characteristics is associated with Type 2 diabetes (previously referred to as non-insulin-dependent diabetes mellitus [NIDDM])? a) Can control blood glucose through diet and exercise Oral hypoglycemic agents may improve blood glucose levels if dietary modification and exercise are unsuccessful.

Description : Which of the following clinical characteristics is associated with Type 2 diabetes (previously referred to as non-insulin-dependent diabetes mellitus [NIDDM])? a) Can control blood glucose ... islet cell antibodies Individuals with Type 2 diabetes do not demonstrate islet cell antibodies.

Last Answer : a) Can control blood glucose through diet and exercise Oral hypoglycemic agents may improve blood glucose levels if dietary modification and exercise are unsuccessful.

Target tissue of insulin is (A) Red blood cells (B) Renal tubular cells (C) GI tract epithelial cells (D) Liver

Description : Target tissue of insulin is (A) Red blood cells (B) Renal tubular cells (C) GI tract epithelial cells (D) Liver

Last Answer : Answer : D

Insulin increases the permeability of glucose across the plasma membrane of muscle cells by (A) Acting on adenylate cycle (B) By loosening the integrity of the membrane (C) Through Ca2+ ions (D) By membrane cruting the hexose carries of intracellular organelles and making them fuse with the plasma membrane

Description : Insulin increases the permeability of glucose across the plasma membrane of muscle cells by (A) Acting on adenylate cycle (B) By loosening the integrity of the membrane (C) Through Ca2 ... membrane cruting the hexose carries of intracellular organelles and making them fuse with the plasma membrane

Last Answer : Answer : D

Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in which Na+ and glucose are co-transported (C) Pyruvate kinase catalyses an irreversible reaction (D) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte

Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte

Last Answer : C

Obesity generally reflects excess intake of energy and is often associated with the development of (A) Nervousness (B) Non-insulin dependent diabetes mellitus (C) Hepatitis (D) Colon cancer

Description : Obesity generally reflects excess intake of energy and is often associated with the development of (A) Nervousness (B) Non-insulin dependent diabetes mellitus (C) Hepatitis (D) Colon cancer

Last Answer : Answer : B

Metformin acts by: A. Releasing insulin from pancreas B. Suppressing gluconeogenesis and glucose output from liver

Description : Metformin acts by: A. Releasing insulin from pancreas B. Suppressing gluconeogenesis and glucose output from liver

Last Answer : B. Suppressing gluconeogenesis and glucose output from liver

People consuming alcohol in heavy quantities generally die of – (1) liver or stomach cancer (2) weakening of heart muscles leading to cardiac arrest (3) blood cancer (4) Cirrhosis

Description : People consuming alcohol in heavy quantities generally die of – (1) liver or stomach cancer (2) weakening of heart muscles leading to cardiac arrest (3) blood cancer (4) Cirrhosis

Last Answer : (4) Cirrhosis Explanation: Cirrhosis is a condition in which the liver does not function properly due to longterm damage. This damage is characterized by the replacement of normal liver tissue by scar tissue.

Heavy alcohol consuming people generally die of (1) blood cancer (2) cirrhosis (3) liver or stomach cancer (4) weakening of heart muscles leading to cardiac arrest

Description : Heavy alcohol consuming people generally die of (1) blood cancer (2) cirrhosis (3) liver or stomach cancer (4) weakening of heart muscles leading to cardiac arrest

Last Answer : (2) cirrhosis Explanation: Cirrhosis is scarring of the liver and poor liver function. It is the final phase of chronic liver disease which may result from a history of excess drinking habits. Cirrhosis is most commonly caused by alcoholism, hepatitis B and hepatitis C, and fatty liver disease.

Heavy alcohol consuming people generally die of (1) blood cancer (2) cirrhosis (3) liver or stomach cancer (4) weakening of heart muscles leading to cardiac arrest

Description : Heavy alcohol consuming people generally die of (1) blood cancer (2) cirrhosis (3) liver or stomach cancer (4) weakening of heart muscles leading to cardiac arrest

Last Answer : cirrhosis

The metabolic actions of adrenaline include the following except: A. Glycogenolysis in liver and muscle B. Inhibition of neoglucogenesis in liver C. Lipolysis in adipose tissue D. Release of potassium from liver followed by its uptake

Description : The metabolic actions of adrenaline include the following except: A. Glycogenolysis in liver and muscle B. Inhibition of neoglucogenesis in liver C. Lipolysis in adipose tissue D. Release of potassium from liver followed by its uptake

Last Answer : B. Inhibition of neoglucogenesis in liver

The metabolic actions of adrenaline include the following except: A. Glycogenolysis in liver and muscle B. Inhibition of neoglucogenesis in liver C. Lipolysis in adipose tissue D. Release of potassium from liver followed by its uptake

Description : The metabolic actions of adrenaline include the following except: A. Glycogenolysis in liver and muscle B. Inhibition of neoglucogenesis in liver C. Lipolysis in adipose tissue D. Release of potassium from liver followed by its uptake

Last Answer : B. Inhibition of neoglucogenesis in liver

Insulin decreases the activity of (A) cAMP dependent protein kinase (B) HMG CoA-reductas (C) Phosphodiesterase (D) Acetyl CoA-carboxylase

Description : Insulin decreases the activity of (A) cAMP dependent protein kinase (B) HMG CoA-reductas (C) Phosphodiesterase (D) Acetyl CoA-carboxylase

Last Answer : Answer : A

Which of the following conditions may be detectable by growth monitoring? 1) Hyperthyroidism 2) Hypothyroidism 3) Pseudohypoparathyroidism 4) XYY Syndrome 5) Insulin dependent diabetes mellitus

Description : Which of the following conditions may be detectable by growth monitoring? 1) Hyperthyroidism 2) Hypothyroidism 3) Pseudohypoparathyroidism 4) XYY Syndrome 5) Insulin dependent diabetes mellitus

Last Answer : Answers-2

Why is glucose needed for the uptake of mineral ions? -Biology

Description : Why is glucose needed for the uptake of mineral ions? -Biology

Last Answer : answer:

Hormone which enhance cellular uptake and utilisation of glucose as well as does hypoglycemia through glucogenesis is

Description : Hormone which enhance cellular uptake and utilisation of glucose as well as does hypoglycemia through glucogenesis is

Last Answer : Hormone which enhance cellular uptake and utilisation of glucose as well as does hypoglycemia through glucogenesis is

Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilization :

Description : Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilization :

Last Answer : Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake ... B. Gastrin C. Insulin D. Glucagon

The effects of glucocorticoid hormones include: a. increase hepatic glycogen synthesis b. decrease glucose uptake by the adipose tissue c. decrease hepatic gluconeogesis d. increase protein synthesis in the skeletal muscles

Description : The effects of glucocorticoid hormones include: a. increase hepatic glycogen synthesis b. decrease glucose uptake by the adipose tissue c. decrease hepatic gluconeogesis d. increase protein synthesis in the skeletal muscles

Last Answer : . increase hepatic glycogen synthesis

Anthelmintic action of piperazine is due to: A. Interference with ATP generation in the worm B. Blockade of glucose uptake by the worm C. Hyperpolarization of nematode muscle by GABA agonistic action D. Depolarization of nematode muscle by activating nicotinic receptors

Description : Anthelmintic action of piperazine is due to: A. Interference with ATP generation in the worm B. Blockade of glucose uptake by the worm C. Hyperpolarization of nematode muscle by GABA agonistic action D. Depolarization of nematode muscle by activating nicotinic receptors

Last Answer : C. Hyperpolarization of nematode muscle by GABA agonistic action

The most probable mechanism of action of mebendazole is: A. Depolarization of membrane and spastic paralysis of the worm B. Hyperpolarization of membrane and flaccid paralysis of the worm C. Loss of intracellular microtubules and inhibition of glucose uptake in the worm D. Tegument damage and leakage of contents of the worm

Description : The most probable mechanism of action of mebendazole is: A. Depolarization of membrane and spastic paralysis of the worm B. Hyperpolarization of membrane and flaccid paralysis of the worm C. Loss of ... inhibition of glucose uptake in the worm D. Tegument damage and leakage of contents of the worm

Last Answer : C. Loss of intracellular microtubules and inhibition of glucose uptake in the worm

Guargum limits post-prandial glycaemia by: A. Inhibiting intestinal brush border α-glucosidases B. Slowing carbohydrate absorption from intestine C. Releasing incretins from the intestine D. Promoting uptake of glucose into skeletal muscles

Description : Guargum limits post-prandial glycaemia by: A. Inhibiting intestinal brush border α-glucosidases B. Slowing carbohydrate absorption from intestine C. Releasing incretins from the intestine D. Promoting uptake of glucose into skeletal muscles

Last Answer : B. Slowing carbohydrate absorption from intestin

The process of breakdown of glycogen to glucose in the liver and pyruvate and lacate in the muscle is known as (A) Glyogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Cellular degradation

Description : The process of breakdown of glycogen to glucose in the liver and pyruvate and lacate in the muscle is known as (A) Glyogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Cellular degradation

Last Answer : Answer : B

Insulin: a. has a half-lilfe of 60 minutes b. stimulate glycolysis in liver and muscle c. stimulate lipogenesis in liver and fat tissues d. is synthesized in the endoplasmic reticulum of the beta cells

Description : Insulin: a. has a half-lilfe of 60 minutes b. stimulate glycolysis in liver and muscle c. stimulate lipogenesis in liver and fat tissues d. is synthesized in the endoplasmic reticulum of the beta cells

Last Answer : is synthesized in the endoplasmic reticulum of the beta cells

Which of the following statements are true of a patient with hyperglycemia and hyponatremia? A. The sodium concentration must be corrected by 5 mEq. per 100 mg. per 100 ml. elevation in blood glucose. B. With normal renal function, this patient is likely to be volume overloaded. C. Proper fluid therapy would be unlikely to include potassium administration. D. Insulin administration will increase the potassium content of cells. E. Early in treatment adequate urine output is a reliable measure of adequate volume resuscitation.

Description : Which of the following statements are true of a patient with hyperglycemia and hyponatremia? A. The sodium concentration must be corrected by 5 mEq. per 100 mg. per 100 ml. elevation in blood ... . E. Early in treatment adequate urine output is a reliable measure of adequate volume resuscitation.

Last Answer : Answer: D DISCUSSION: Each 100-mg. per 100 ml. elevation in blood glucose causes a fall in serum sodium concentration of approximately 2 mEq. per liter. Excess serum glucose ... correction of the patient's associated acidosis produce movement of potassium ions into the intracellular compartment

Adrenaline raises blood glucose level by the following actions except (a) Inducing hepatic glycogenolysis (b) Inhibiting insulin secretion from pancreatic ß cells (c) Augmenting glucagons secretion from pancreatic a cells (d) Inhibiting peripheral glucose utilization

Description : Adrenaline raises blood glucose level by the following actions except (a) Inducing hepatic glycogenolysis (b) Inhibiting insulin secretion from pancreatic ß cells (c) Augmenting glucagons secretion from pancreatic a cells (d) Inhibiting peripheral glucose utilization

Last Answer : Ans: D

Which of the following statements is NOT true about diabetes mellitus? A) Type II diabetes is much more common than type I. B) Insulin injections are required in both type I and type II diabetes. C) Type I diabetes occurs as a result of destruction of the insulin-producing cells. D) One method of treating type II diabetes is exercise and a low-fat, low-sugar diet. E) Symptoms of diabetes include excessive thirst, frequent urination, and glucose in the urine.

Description : Which of the following statements is NOT true about diabetes mellitus? A) Type II diabetes is much more common than type I. B) Insulin injections are required in both type I and type II ... -sugar diet. E) Symptoms of diabetes include excessive thirst, frequent urination, and glucose in the urine.

Last Answer : B) Insulin injections are required in both type I and type II diabetes.

Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Last Answer : D. Inhibiting peripheral glucose utilization

Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization

Last Answer : D. Inhibiting peripheral glucose utilization

All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it

Description : All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it

Last Answer : Answer : D

Insulin like growth hormones are produced by (A) Hypophysis (B) Liver (C) Pancreas (D) Thyroid

Description : Insulin like growth hormones are produced by (A) Hypophysis (B) Liver (C) Pancreas (D) Thyroid

Last Answer : Answer : B

A specific fructokinase present in liver has a very high affinity for its substrate because (A) Km for fructose is very high (B) Km for fructose is very low (C) Activity is affected by fasting (D) Activity is affected by insulin

Description : A specific fructokinase present in liver has a very high affinity for its substrate because (A) Km for fructose is very high (B) Km for fructose is very low (C) Activity is affected by fasting (D) Activity is affected by insulin

Last Answer : Answer : B

A characteristic feature of Kwashiorkar is (A) Fatty liver (B) Emaciation (C) Low insulin lever (D) Occurrence in less than 1 year infant

Description : A characteristic feature of Kwashiorkar is (A) Fatty liver (B) Emaciation (C) Low insulin lever (D) Occurrence in less than 1 year infant

Last Answer : Answer : A