Apolipoprotein A-I acts as (A) Enzyme activator (B) Ligand for receptor (C) Both (A) and (B) (D) None of these

Apolipoprotein A-I acts as (A) Enzyme activator (B) Ligand for receptor (C) Both (A) and (B) (D) None of these
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Apolipoprotien B-100 acts as (A) Enzyme activator (B) Ligand for receptor (C) Both (A) and (B) (D) None of these

Description : Apolipoprotien B-100 acts as (A) Enzyme activator (B) Ligand for receptor (C) Both (A) and (B) (D) None of these

Last Answer : Answer : B

The apolipoprotein which acts as ligand for LDL receptor is (A) B-48 (B) B-100 (C) A (D) C

Description : The apolipoprotein which acts as ligand for LDL receptor is (A) B-48 (B) B-100 (C) A (D) C

Last Answer : Answer : B

The apolipoprotein which acts as activator of LCAT is (A) A-I (B) A-IV (C) C-II (D) D

Description : The apolipoprotein which acts as activator of LCAT is (A) A-I (B) A-IV (C) C-II (D) D

Last Answer : Answer : A

Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase

Description : Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase

Last Answer : Answer : C

Fibrinolytic therapy is based on activation of plasminogen, the inactive proteolytic enzyme of plasma that binds to fibrin during the formation of thrombosis. Activation of plasminogen to plasmin results in selective thrombolysis at the fibrin clot surface. Which of the following statement(s) is/are true concerning agents used in thrombolytic therapy? a. Streptokinase is a bacterial protein which is antigenic in humans, resulting in allergic reactions in up to l5% of cases b. Tissue plasminogen activator acts directly on plasmin without an intermediate drug–plasmin complex c. The half-life of urokinase, streptokinase, and TPA all exceed 30 minutes d. Streptokinase is significantly cheaper than urokinase or TPA

Description : Fibrinolytic therapy is based on activation of plasminogen, the inactive proteolytic enzyme of plasma that binds to fibrin during the formation of thrombosis. Activation of plasminogen to plasmin results ... TPA all exceed 30 minutes d. Streptokinase is significantly cheaper than urokinase or TPA

Last Answer : Answer: a, b, d Streptokinase is a bacterial protein produced by group C b-hemolytic streptococci. It is therefore antigenic in humans and can be associated with allergic reaction in ... one agent over the other. Streptokinase however, is markedly less expensive than either urokinase or TPA

The apolipoprotein which acts as actiator of extrahepatic lipoprotein is (A) Apo-A (B) Apo-B (C) Apo-C (D) Apo-D

Description : The apolipoprotein which acts as actiator of extrahepatic lipoprotein is (A) Apo-A (B) Apo-B (C) Apo-C (D) Apo-D

Last Answer : Answer : C

G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins

Description : G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins

Last Answer : are activated by the binding of an extracellular ligand to a membrane receptor

An inorganic ion required for the activity of an enzyme is known as (A) Activator (B) Cofactor (C) Coenzyme (D) None of these

Description : An inorganic ion required for the activity of an enzyme is known as (A) Activator (B) Cofactor (C) Coenzyme (D) None of these

Last Answer : Answer : B

In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate

Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate

Last Answer : Answer : A

In urea synthesis, the amino acid functioning solely as an enzyme activator: (A) N-acetyl glutamate(B) Ornithine (C) Citrulline (D) Arginine

Description : In urea synthesis, the amino acid functioning solely as an enzyme activator: (A) N-acetyl glutamate(B) Ornithine (C) Citrulline (D) Arginine

Last Answer : Answer : A

Apolipoprotein B-100 is present in (A) Chylomicrons (B) VLDL only (C) LDL only (D) VLDL and LDL

Description : Apolipoprotein B-100 is present in (A) Chylomicrons (B) VLDL only (C) LDL only (D) VLDL and LDL

Last Answer : Answer : B

Apolipoprotein B-48 is present in (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Description : Apolipoprotein B-48 is present in (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

Last Answer : Answer : A

Apolipoprotein B-48 is synthesized in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine

Description : Apolipoprotein B-48 is synthesized in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine

Last Answer : Answer : C

Apolipoprotein B-100 is synthesised in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine

Description : Apolipoprotein B-100 is synthesised in (A) Adipose tissue (B) Liver (C) Intestine (D) Liver and intestine

Last Answer : Answer : B

The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Description : The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Last Answer : Answer : D

The apolipoprotein which from the integral component of VLDL is (A) B-100 (B) B-48 (C) A (D) D

Description : The apolipoprotein which from the integral component of VLDL is (A) B-100 (B) B-48 (C) A (D) D

Last Answer : Answer : A

The apolipoprotein which forms the integral component of chylomicron is (A) B-100 (B) B-48 (C) C (D) D

Description : The apolipoprotein which forms the integral component of chylomicron is (A) B-100 (B) B-48 (C) C (D) D

Last Answer : Answer : B

If a coenzyme is required in an enzyme reaction, the former usually has the function of (A) Acting as an acceptor for one of the cleavage products of the substrate (B) Enhancing the specificity of the apo enzyme (C) Increasing the number of receptor sites of the apo enzyme (D) Activating the substrate ENZYMES 167

Description : If a coenzyme is required in an enzyme reaction, the former usually has the function of (A) Acting as an acceptor for one of the cleavage products of the substrate (B) Enhancing the specificity ... C) Increasing the number of receptor sites of the apo enzyme (D) Activating the substrate ENZYMES 167

Last Answer : Answer : A

Cytosolic and mitochondrial carbamoyl phosphate synthetase have the following similarity: (A) Both use ammonia as a substance (B) Both provide carbamoyl phosphate for urea synthesis (C) Both require N-acetylglutamate as an activator (D) Both are allosteric enzymes

Description : Cytosolic and mitochondrial carbamoyl phosphate synthetase have the following similarity: (A) Both use ammonia as a substance (B) Both provide carbamoyl phosphate for urea synthesis (C) Both require N-acetylglutamate as an activator (D) Both are allosteric enzymes

Last Answer : Answer : C

The lone pair of electrons at one of the ring nitrogens in the given amino acid makes a potential ligand, which is important in binding the iron atoms in hemoglobin: (A) Tryptophan (B) Threonine (C) Histidine (D) Serine

Description : The lone pair of electrons at one of the ring nitrogens in the given amino acid makes a potential ligand, which is important in binding the iron atoms in hemoglobin: (A) Tryptophan (B) Threonine (C) Histidine (D) Serine

Last Answer : Answer : C

The bond formed between the transition metal ion and ligand is ?

Description : The bond formed between the transition metal ion and ligand is ?

Last Answer : Co-ordination covalent bond Transitional metal Ions can form complex compounds by. By accepting the lone pair of electrons from ligand

An enzyme which acts as allosteric regulator and sensitive to both phosphate concentration and to the purine nucleotides is (A) PRPP synthetase (B) PRPP glutamyl midotransferase (C) HGPR Tase (D) Formyl transferase

Description : An enzyme which acts as allosteric regulator and sensitive to both phosphate concentration and to the purine nucleotides is (A) PRPP synthetase (B) PRPP glutamyl midotransferase (C) HGPR Tase (D) Formyl transferase

Last Answer : Answer : A

Name the enzyme that acts both as carboxylase at one time and oxygenase at another time. (A) PEP carboxylase (B) RuBP carboxylase (C) Carbonic anyhdrase (D) None of these

Description : Name the enzyme that acts both as carboxylase at one time and oxygenase at another time. (A) PEP carboxylase (B) RuBP carboxylase (C) Carbonic anyhdrase (D) None of these

Last Answer : Answer : B

The first protein synthesized by recombinant DNA technology was (A) Streptokinase (B) Human growth hormone (C) Tissue plasminogen activator (D) Human insulin

Description : The first protein synthesized by recombinant DNA technology was (A) Streptokinase (B) Human growth hormone (C) Tissue plasminogen activator (D) Human insulin

Last Answer : Answer : D

Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) Attaching to promoter region and facilitating the binding of RNA polymerase holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus

Description : Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) ... holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus

Last Answer : Answer : D

Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these

Description : Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these

Last Answer : Answer : C

The enzymes encoded by z, y and a genes of lac operon are inducible, and their inducer is (A) Lactose (B) Allo-lactose (C) Catabolite gene activator protein (D) All of these

Description : The enzymes encoded by z, y and a genes of lac operon are inducible, and their inducer is (A) Lactose (B) Allo-lactose (C) Catabolite gene activator protein (D) All of these

Last Answer : Answer : B

The catabolite repression is mediated by a catabolite gene activator protein (CAP) in conjunction with (A) AMP (B) GMP (C) cAMP (D) Cgmp

Description : The catabolite repression is mediated by a catabolite gene activator protein (CAP) in conjunction with (A) AMP (B) GMP (C) cAMP (D) Cgmp

Last Answer : Answer : C

Fructose 2, 3 bi phosphate is a powerful allosteric activator of (A) Fructose 1, 6 diphosphatase (B) Phosphofructokinase (C) Hexokinase (D) Fructokinase

Description : Fructose 2, 3 bi phosphate is a powerful allosteric activator of (A) Fructose 1, 6 diphosphatase (B) Phosphofructokinase (C) Hexokinase (D) Fructokinase

Last Answer : Answer : B

Allosteric activator of glycogen synthase is (A) Glucose (B) Glucose-6-Phosphate (C) UTP (D) Glucose-1-phosphate

Description : Allosteric activator of glycogen synthase is (A) Glucose (B) Glucose-6-Phosphate (C) UTP (D) Glucose-1-phosphate

Last Answer : Answer : B

GABA(gama amino butyric acid) is (A) Post-synaptic excitatory transmitter (B) Post-synaptic inhibitor transmitter (C) activator of glia-cell function (D) inhibitor of glia-cell function

Description : GABA(gama amino butyric acid) is (A) Post-synaptic excitatory transmitter (B) Post-synaptic inhibitor transmitter (C) activator of glia-cell function (D) inhibitor of glia-cell function

Last Answer : Answer : B

Allsoteric activator of glutamate dehydrogenase is (A) ATP (B) GTP (C) ADP and GDP (D) AMP and GMP

Description : Allsoteric activator of glutamate dehydrogenase is (A) ATP (B) GTP (C) ADP and GDP (D) AMP and GMP

Last Answer : Answer : C

Receptors perform the following function/functions: A. Ligand recognition B. Signal transduction C. Both ligand recognition and signal transduction D. Disposal of agonists and antagonists

Description : Receptors perform the following function/functions: A. Ligand recognition B. Signal transduction C. Both ligand recognition and signal transduction D. Disposal of agonists and antagonists

Last Answer : C. Both ligand recognition and signal transduction

Receptors perform the following function/functions: A. Ligand recognition B. Signal transduction C. Both ligand recognition and signal transduction D. Disposal of agonists and antagonists

Description : Receptors perform the following function/functions: A. Ligand recognition B. Signal transduction C. Both ligand recognition and signal transduction D. Disposal of agonists and antagonists

Last Answer : C. Both ligand recognition and signal transduction

The hormone which acts through intracellular receptor protein is

Description : The hormone which acts through intracellular receptor protein is

Last Answer : The hormone which acts through intracellular receptor protein is A. Growth hormone B. Prolactin C. Thyroxine D. Adrenaline

Cell regulation can be thought of as the effector side of cell communication. Most commonly cell regulation occurs by means of extracellular chemical messengers. Which of the following statement(s) is/are true concerning these messengers? a. Paracrine regulation involves a messenger which is produced and acts systemically b. The extracellular signal or stimulus is received by a receptor on or in the target cell c. Neurocrine regulation depends on a physical connection between the neuron and the target cell d. Most hormones, local mediators, and neurotransmitters readily cross the cell plasma membrane

Description : Cell regulation can be thought of as the effector side of cell communication. Most commonly cell regulation occurs by means of extracellular chemical messengers. Which of the following statement(s ... d. Most hormones, local mediators, and neurotransmitters readily cross the cell plasma membrane

Last Answer : Answer: b, c Depending on how the extracellular messenger arrives, cell regulation can be classified as paracrine, endocrine, or neurocrine. In paracrine regulation, a chemical messenger ... , local mediators, and neurotransmitters are water-soluble and cannot readily cross the plasma membrane

The following are true about parathyroid hormone a. it is an 84 amino acid peptide hormone b. it increases calcium absorption from the gastrointestinal tract c. it acts on a cell surface receptor that increases intracellular cyclic AMP d. all above

Description : The following are true about parathyroid hormone a. it is an 84 amino acid peptide hormone b. it increases calcium absorption from the gastrointestinal tract c. it acts on a cell surface receptor that increases intracellular cyclic AMP d. all above

Last Answer : all above

Aliskiren acts by (A) inhibiting the conversion of Angiotensin I to II (B) inhibiting the release of rennin (C) inhibiting the binding of Angiotensin II to the receptor (D) inhibiting the action of aldosterone

Description : Aliskiren acts by (A) inhibiting the conversion of Angiotensin I to II (B) inhibiting the release of rennin (C) inhibiting the binding of Angiotensin II to the receptor (D) inhibiting the action of aldosterone

Last Answer : (B) inhibiting the release of rennin

Select the opioid analgesic which acts primarily through κ (kappa) opioid receptor: A. Pentazocine B. Methadone C. Buprenorphine D. Pethidine

Description : Select the opioid analgesic which acts primarily through κ (kappa) opioid receptor: A. Pentazocine B. Methadone C. Buprenorphine D. Pethidine

Last Answer : A. Pentazocine

Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia

Description : Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia

Last Answer : C. Mediates low ceiling respiratory depression

Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above

Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above

Last Answer : D. All of the above

6.2 Which hormone acts through a cytoplasmic receptor: A. Calcitriol B. Prolactin C. Vasopressin D. None of the abov

Description : 6.2 Which hormone acts through a cytoplasmic receptor: A. Calcitriol B. Prolactin C. Vasopressin D. None of the abov

Last Answer : A.Calcitol binds to cytoplasmic membrane and enhances the absorption of Calcium by increasing the calcium binding proteins-calbindin-D proteins.

Apolipoprotein CII?

Description : Apolipoprotein CII?

Last Answer : DefinitionApolipoprotein CII (apoCII) is a protein found in large fat particles absorbed from the gastrointestinal tract. It is also found in very low density lipoprotein (VLDL), which is made up of mostly ... a needle into the vein. The blood collects into an airtight vial or tube attached to t

An enzyme promotes a chemical reaction by (A) Lowering the energy of activation (B) Causing the release of heat which acts as a primer (C) Increasing molecular motion (D) Changing the free energy difference between substrate and product

Description : An enzyme promotes a chemical reaction by (A) Lowering the energy of activation (B) Causing the release of heat which acts as a primer (C) Increasing molecular motion (D) Changing the free energy difference between substrate and product

Last Answer : Answer : A

NADPH is produced when this enzyme acts (A) Pyruvate dehydrogenase (B) Malic enzyme (C) Succinate dehydrogenase (D) Malate dehydrogenase

Description : NADPH is produced when this enzyme acts (A) Pyruvate dehydrogenase (B) Malic enzyme (C) Succinate dehydrogenase (D) Malate dehydrogenase

Last Answer : Answer : B

Pancreatic lipose is an enzyme which hydrolyzes facts. It acts as a/an (A) peptidase (B) hydrolase (C) carbohydrates (D) dehydrogenase

Description : Pancreatic lipose is an enzyme which hydrolyzes facts. It acts as a/an (A) peptidase (B) hydrolase (C) carbohydrates (D) dehydrogenase

Last Answer : Answer : B

The branching enzyme acts on the glycogen when the glycogen chain has been lengthened to between glucose units: (A) 1 and 6 (B) 2 and 7 (C) 3 and 9 (D) 6 and 11

Description : The branching enzyme acts on the glycogen when the glycogen chain has been lengthened to between glucose units: (A) 1 and 6 (B) 2 and 7 (C) 3 and 9 (D) 6 and 11

Last Answer : D

Adrenaline acts on which enzyme?

Description : Adrenaline acts on which enzyme?

Last Answer : Glycogen phosphorylase.

At the adrenergic synapse, the concentration of adrenaline in synaptic cleft: a. increased by cocaine which inhibit reuptake of adrenaline b. decreased by MAO (monoamine oxidase) - inhibitors c. controlled chiefly by the activity of the enzyme COMT d. increased by noradrenaline receptor blockers

Description : At the adrenergic synapse, the concentration of adrenaline in synaptic cleft: a. increased by cocaine which inhibit reuptake of adrenaline b. decreased by MAO (monoamine oxidase) - inhibitors c. controlled chiefly by the activity of the enzyme COMT d. increased by noradrenaline receptor blockers

Last Answer : increased by cocaine which inhibit reuptake of adrenaline

The rate limiting step in cholesterol biosynthesis is one of the followings : (A) LDL-receptor concentration (B) VLDL secretion (C) Mevalonic acid formation (D) Co-enzyme A formation

Description : The rate limiting step in cholesterol biosynthesis is one of the followings : (A) LDL-receptor concentration (B) VLDL secretion (C) Mevalonic acid formation (D) Co-enzyme A formation

Last Answer : (C) Mevalonic acid formation