Description : Apolipoprotein A-I acts as (A) Enzyme activator (B) Ligand for receptor (C) Both (A) and (B) (D) None of these
Last Answer : Answer : C
Description : The apolipoprotein which acts as ligand for LDL receptor is (A) B-48 (B) B-100 (C) A (D) C
Last Answer : Answer : B
Description : Fibrinolytic therapy is based on activation of plasminogen, the inactive proteolytic enzyme of plasma that binds to fibrin during the formation of thrombosis. Activation of plasminogen to plasmin results ... TPA all exceed 30 minutes d. Streptokinase is significantly cheaper than urokinase or TPA
Last Answer : Answer: a, b, d Streptokinase is a bacterial protein produced by group C b-hemolytic streptococci. It is therefore antigenic in humans and can be associated with allergic reaction in ... one agent over the other. Streptokinase however, is markedly less expensive than either urokinase or TPA
Description : G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins
Last Answer : are activated by the binding of an extracellular ligand to a membrane receptor
Description : The apolipoprotein which acts as activator of LCAT is (A) A-I (B) A-IV (C) C-II (D) D
Last Answer : Answer : A
Description : An inorganic ion required for the activity of an enzyme is known as (A) Activator (B) Cofactor (C) Coenzyme (D) None of these
Description : In gluconeogensis, an allosteric activator required in the synthesis of oxaloacetate from bicarbonate and pyruvate, which is catalysed by the enzyme pyruvate carboxylase is (A) Acetyl CoA (B) Succinate (C) Isocitrate (D) Citrate
Description : In urea synthesis, the amino acid functioning solely as an enzyme activator: (A) N-acetyl glutamate(B) Ornithine (C) Citrulline (D) Arginine
Description : If a coenzyme is required in an enzyme reaction, the former usually has the function of (A) Acting as an acceptor for one of the cleavage products of the substrate (B) Enhancing the specificity ... C) Increasing the number of receptor sites of the apo enzyme (D) Activating the substrate ENZYMES 167
Description : Cytosolic and mitochondrial carbamoyl phosphate synthetase have the following similarity: (A) Both use ammonia as a substance (B) Both provide carbamoyl phosphate for urea synthesis (C) Both require N-acetylglutamate as an activator (D) Both are allosteric enzymes
Description : The lone pair of electrons at one of the ring nitrogens in the given amino acid makes a potential ligand, which is important in binding the iron atoms in hemoglobin: (A) Tryptophan (B) Threonine (C) Histidine (D) Serine
Description : The bond formed between the transition metal ion and ligand is ?
Last Answer : Co-ordination covalent bond Transitional metal Ions can form complex compounds by. By accepting the lone pair of electrons from ligand
Description : An enzyme which acts as allosteric regulator and sensitive to both phosphate concentration and to the purine nucleotides is (A) PRPP synthetase (B) PRPP glutamyl midotransferase (C) HGPR Tase (D) Formyl transferase
Description : Name the enzyme that acts both as carboxylase at one time and oxygenase at another time. (A) PEP carboxylase (B) RuBP carboxylase (C) Carbonic anyhdrase (D) None of these
Description : The first protein synthesized by recombinant DNA technology was (A) Streptokinase (B) Human growth hormone (C) Tissue plasminogen activator (D) Human insulin
Last Answer : Answer : D
Description : Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) ... holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus
Description : Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these
Description : The enzymes encoded by z, y and a genes of lac operon are inducible, and their inducer is (A) Lactose (B) Allo-lactose (C) Catabolite gene activator protein (D) All of these
Description : The catabolite repression is mediated by a catabolite gene activator protein (CAP) in conjunction with (A) AMP (B) GMP (C) cAMP (D) Cgmp
Description : Fructose 2, 3 bi phosphate is a powerful allosteric activator of (A) Fructose 1, 6 diphosphatase (B) Phosphofructokinase (C) Hexokinase (D) Fructokinase
Description : Allosteric activator of glycogen synthase is (A) Glucose (B) Glucose-6-Phosphate (C) UTP (D) Glucose-1-phosphate
Description : GABA(gama amino butyric acid) is (A) Post-synaptic excitatory transmitter (B) Post-synaptic inhibitor transmitter (C) activator of glia-cell function (D) inhibitor of glia-cell function
Description : Allsoteric activator of glutamate dehydrogenase is (A) ATP (B) GTP (C) ADP and GDP (D) AMP and GMP
Description : Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase
Description : LDL receptor is specific for (A) Apo B-48 and Apo B 100 (B) Apo B-48 and Apo E (C) Apo B-100 and Apo D (D) Apo B-100 and apo D
Description : Receptors perform the following function/functions: A. Ligand recognition B. Signal transduction C. Both ligand recognition and signal transduction D. Disposal of agonists and antagonists
Last Answer : C. Both ligand recognition and signal transduction
Description : The hormone which acts through intracellular receptor protein is
Last Answer : The hormone which acts through intracellular receptor protein is A. Growth hormone B. Prolactin C. Thyroxine D. Adrenaline
Description : Cell regulation can be thought of as the effector side of cell communication. Most commonly cell regulation occurs by means of extracellular chemical messengers. Which of the following statement(s ... d. Most hormones, local mediators, and neurotransmitters readily cross the cell plasma membrane
Last Answer : Answer: b, c Depending on how the extracellular messenger arrives, cell regulation can be classified as paracrine, endocrine, or neurocrine. In paracrine regulation, a chemical messenger ... , local mediators, and neurotransmitters are water-soluble and cannot readily cross the plasma membrane
Description : The following are true about parathyroid hormone a. it is an 84 amino acid peptide hormone b. it increases calcium absorption from the gastrointestinal tract c. it acts on a cell surface receptor that increases intracellular cyclic AMP d. all above
Last Answer : all above
Description : Aliskiren acts by (A) inhibiting the conversion of Angiotensin I to II (B) inhibiting the release of rennin (C) inhibiting the binding of Angiotensin II to the receptor (D) inhibiting the action of aldosterone
Last Answer : (B) inhibiting the release of rennin
Description : Select the opioid analgesic which acts primarily through κ (kappa) opioid receptor: A. Pentazocine B. Methadone C. Buprenorphine D. Pethidine
Last Answer : A. Pentazocine
Description : Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia
Last Answer : C. Mediates low ceiling respiratory depression
Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above
Last Answer : D. All of the above
Description : 6.2 Which hormone acts through a cytoplasmic receptor: A. Calcitriol B. Prolactin C. Vasopressin D. None of the abov
Last Answer : A.Calcitol binds to cytoplasmic membrane and enhances the absorption of Calcium by increasing the calcium binding proteins-calbindin-D proteins.
Description : An enzyme promotes a chemical reaction by (A) Lowering the energy of activation (B) Causing the release of heat which acts as a primer (C) Increasing molecular motion (D) Changing the free energy difference between substrate and product
Description : NADPH is produced when this enzyme acts (A) Pyruvate dehydrogenase (B) Malic enzyme (C) Succinate dehydrogenase (D) Malate dehydrogenase
Description : Pancreatic lipose is an enzyme which hydrolyzes facts. It acts as a/an (A) peptidase (B) hydrolase (C) carbohydrates (D) dehydrogenase
Description : The branching enzyme acts on the glycogen when the glycogen chain has been lengthened to between glucose units: (A) 1 and 6 (B) 2 and 7 (C) 3 and 9 (D) 6 and 11
Last Answer : D
Description : Adrenaline acts on which enzyme?
Last Answer : Glycogen phosphorylase.
Description : At the adrenergic synapse, the concentration of adrenaline in synaptic cleft: a. increased by cocaine which inhibit reuptake of adrenaline b. decreased by MAO (monoamine oxidase) - inhibitors c. controlled chiefly by the activity of the enzyme COMT d. increased by noradrenaline receptor blockers
Last Answer : increased by cocaine which inhibit reuptake of adrenaline
Description : The rate limiting step in cholesterol biosynthesis is one of the followings : (A) LDL-receptor concentration (B) VLDL secretion (C) Mevalonic acid formation (D) Co-enzyme A formation
Last Answer : (C) Mevalonic acid formation
Description : efficacy of an activator adjuvant is a function of a). Adjuvant only b). Herbicide only c). Both a&b d). Antagonism
Last Answer : c). Both a&b
Description : Explain the following : (i) Low spin octahedral complexes of nickel are not known. (ii) The π-complexes are known for transition elements only. (iii) CO is a stronger ligand than NTL, for many metals. -Chemistry
Last Answer : (i) The electronic configuration of Ni is [Ar] 3d8 4s2 which shows that it can only form two types of complexes i.e. square planar (dsp2) in presence of strong ligand and tetrahedral (sp3) in ... more splitting of d-orbitals and moreover it is also able to form π bond due to back bonding.
Description : Giving a suitable example for each, explain the following : (i) Crystal field splitting (ii) Linkage isomerism (iii) Ambidentate ligand -Chemistry
Last Answer : i) Crystal field splitting: It is the splitting of the degenerate energy levels due to the presence of ligands. When ligand approaches a transition metal ion, the degenerate d-orbitals split into two ... the nitrogen atom or one of the oxygen atoms. Example : - SCN thiocyanate, - NCS isothiocyanate
Description : Assertion :- Oxidation number of `Ni` in `[Ni(CO)_(4)]` is zero. ltbr. Reason :- Nickel is bonded to neutral ligand, carbonyl.
Last Answer : Assertion :- Oxidation number of `Ni` in `[Ni(CO)_(4)]` is zero. ltbr. Reason :- Nickel is ... is False. D. If both Assertion & Reason are False.
Description : The strong field ligand is "
Last Answer : The strong field ligand is " A. `SCN^(-)` B. `NO_(2)^(-)` C. `I^(-)` D. `S^(2-)`
Description : Which molecule/ion among the following cannot act as a ligand in complex compounds ?
Last Answer : Which molecule/ion among the following cannot act as a ligand in complex compounds ? A. `CH_(4)` B. `CN^(-)` C. `Br^(-)` D. `CO`
Description : Nickel `(Z=28)` combines with a uninegative monodentate ligand `X^(-)` to form a paramagnetic complex `[NiX_4]^(2-)`. The number of unpaired electron(
Last Answer : Nickel `(Z=28)` combines with a uninegative monodentate ligand `X^(-)` to form a paramagnetic complex ... C. one, square planar D. two, square planar
Description : Ethylene diamine is an example of a ……… ligand:
Last Answer : Ethylene diamine is an example of a ……… ligand: A. monodentate B. bidentate C. tridentate D. hexadentate