Description : FAD containing enzyme, catalyzing formation of α, β unsaturated fatty acyl CoA derivative. (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thiolase
Last Answer : Answer : A
Description : Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves (A) Carnitine acyl transferase (B) Pyruvate dehydrogenase (C) Citrate lyase (D) Thiolase
Last Answer : Answer : C
Description : The formation of ∆2-trans-enoyl-CoA from acyl-CoA requires the enzyme: (A) Acyl-CoA synthetase (B) Acyl-CoA dehydrogenase (C) 3-Hydroxy acyl-CoA dehydrogenase (D) Thiolase
Last Answer : Answer : B
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive reactions catalysed by 4-enzymes. These act the following order: (A) Acetyl CoA dehydrogenase, ... CoA dehydrogenase (D) Enoyl hydrase, β-OH acyl CoA dehydrogenase, acyl CoA dehydrogenase, thiolose,
Description : Jamaican vomiting sickness is due to inactivation of the enzyme (A) Pyruvate carboxylase (B) Acyl-Co-A synthetase (C) Acyl-Co-A dehydrogense (D) Thiolase
Description : Some hormones produce their intracellular effects by activating (A) Phospholipae A1 (B) Phospholipase B (C) Phospholipase C (D) All of these
Description : Lysolecithin is formed from lecithin by the action of (A) Phospholipase A1 (B) Phospholipase A2 (C) Phospholipase C (D) Phospholipase D
Description : Anti-inflammatory corticosteroids inhibit (A) Phospholipase A1 (B) Phospholipase A2 (C) Cyclo-oxygenase (D) Lipo-oxygenase
Description : Phenylbutazone and indomethacin inhibit (A) Phospholipase A1 (B) Phospholipase A2 (C) Cyclo-oxygenase (D) Lipo-oxygenase
Description : A ’suicide enzyme’ is (A) Cycloxygenase (B) Lipooxygenase (C) Phospholipase A1 (D) Phospholipase A2
Description : Aspirin inhibits the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipae A1 (D) Phospholipase A2
Description : In β-oxidation 3-ketoacyl-CoA is splitted at the 2, 3 position by the enzyme: (A) Hydratase (B) Dehydrogenase (C) Reducatse (D) Thiolase
Last Answer : Answer : D
Description : Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase
Description : This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP: (A) Acyl CoA dehydrogenase (B) Enoyl hydrase (C) β-OH acyl CoA dehydrogenase (D) Thio kinase
Description : In β-oxidation, the coenzyme for acyl-CoA dehydrogenase is (A) FMN (B) NAD (C) NADP (D) FAD
Description : Riboflavin is a coenzyme in the reaction catalysed by the enzyme (A) Acyl CoA synthetase (B) Acyl CoA dehydrogenase (C) β-Hydroxy acyl CoA (D) Enoyl CoA dehydrogenase
Description : Acyl-CoA dehydrogenase converts Acyl CoA to α-β unsaturated acyl-CoA in presence of the coenzyme: (A) NAD+ (B) NADP+ (C) ATP (D) FAD
Description : Lesch-Nyhan syndrome, the sex linked, recessive absence of HGPRTase, may lead to (A) Compulsive self destructive behaviour with elevated levels of urate in serum (B) Hypouricemia due to liver damage (C) Failure to thrive and megaloblastic anemia (D) Protein intolerance and hepatic encephalopathy
Description : In adrenogenital syndrome due to total absence of 21-hydroxylase in adrenal cortex, there is (A) Deficient secretion of glucocorticoids (B) Deficient secretion of mineralcorticoids (C) Excessive secretion of androgens (D) All of these
Description : Bassen-Kornzweig syndrome is due to (A) Absence of Apo-C-II (B) Defect in Apo-B synthesis (C) Absence of Apo-E (D) Absence of Apo-D
Description : Hyperammonaemia type I results from congenital absence of (A) Glutamate dehydrogenase (B) Carbamoyl phosphate synthetase (C) Ornithine transcarbamoylase (D) None of these
Description : Of the following hemolytic anemias, which is categorized as inherited? a) Sickle cell anemia Glucose 6-phosphate dehydrogenase deficiency is an inherited abnormality resulting in hemolytic anemia. b ... is an acquired anemia. d) Hypersplenism Hypersplenism results in an acquired hemolytic anemia.
Last Answer : a) Sickle cell anemia Glucose 6-phosphate dehydrogenase deficiency is an inherited abnormality resulting in hemolytic anemia.
Description : HMG-CoA is converted to mevalonate by reduction catalysed by (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Mevalonate kinase (D) Thiolase
Description : Two molecules of acetyl-CoA condense to form acetoacetyl-CoA catalysed by (A) Thiolase (B) Kinase (C) Reductase (D) Isomerase
Description : Hunter’s syndrome results from absence of (A) Hexosaminidase A (B) Iduronate sulphatase (C) Neuraminidase (D) Arylsulphatase B
Description : Complete absence of hypoxanthine guanine phospharibosyl transferase causes (A) Primary gout (B) Immunodeficiency (C) Uric acid stones (D) Lesh-Nyhan syndrome
Description : Mc Ardle’s syndrome is characterized by the absence of (A) Liver phosphorylase (B) Muscle phosphorylase (C) Branching enzyme (D) Debranching enzyme
Description : Phenytoin: 1) is a benzalkonium Derivative 2) is clinically effective serum level is in the range on 2-10 micrograms/ml. 3) A steady state blood level is achieved by 2-5 days 4) Can be used in management of alchohol withdrawl syndrome 5) Is the drug of choice in absence seizures.
Last Answer : Answers-4 Phenytoin is an imidazolidine derivative.It relates to barbiturates in chemical structure. Clinically effective seum level is in the range on 10-20 micrograms/ml. A steady state blood level is achieved by 7-10 days.
Description : Nondisjunction of a chromosome results in which of the following diagnoses? a) Down Syndrome When a pair of chromosomes fails to separate completely and creates a sperm or oocyte that contains two ... genetic condition that may occur in a single family member as a result of spontaneous mutation.
Last Answer : a) Down Syndrome When a pair of chromosomes fails to separate completely and creates a sperm or oocyte that contains two copies of a particular chromosome (nondisjunction) Down syndrome results from three number 21 chromosomes.
Description : Phospholipase C is activated by (A) Gs proteins (B) Gi proteins (C) Gq proteins (D) G12 proteins
Description : Activated phospholipase C acts on (A) Phosphatidyl inositol-4, 5-biphosphate (B) Inositol-1, 4, 5-triphosphate (C) Protein kinase C (D) Pl-3 kinase
Description : Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase
Description : Phospholipase C attacks the ester bond liberating 1, 2-diacylglycerol and a phosphoryl base at position (A) 1 (B) 2 (C) Both (A) and (B) (D) 3
Description : Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipase A2 (D) Lipoprotein lipase
Description : Phospholipase A2 is an enzyme which removes a fatty acid residue from lecithin to form (A) Lecithin fragments (B) Phosphotidic acid (C) Glyceryl phosphate (D) Lysolecithin
Description : The d igest ive enzymes of ce l lu lar compounds are confined to (A) Lysosomes (B) Ribosomes (C) Peroxisomes (D) Polysomes
Last Answer : A
Description : Q. What are peroxisomes?
Last Answer : A. They contain peroxidase and catalase, necessary for destroying the unwanted free radicals.
Description : Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in ... with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure
Last Answer : Answers-2 Hyperuricaemia may be due to increased purine intake, urate production or reduced urate clearance, and is most commonly due to the latter. Therefore it can occur in association with enhanced ... . Many of the uricosuric drugs may be detrimental in renal failure and may not be effective.
Description : The molecule of vitamin A1 contains (A) Benzene ring (B) β-Ionone ring (C) β-Carotene ring (D) None of these
Description : Glutathione is a constituent of (A) Leukotriene A4 (B) Thromboxane A1 (C) Leukotriene C4 (D) None of these
Description : Which of the following statement(s) is/are true concerning the various types of shock? a. Traumatic shock is more commonly associated with subsequent organ injury and multiorgan failure ... responds quickly to resuscitation e. Neurogenic shock occurs with the absence of sympathetic activity
Last Answer : Answer: a, b, d, e Classification schemes of shock based on cause have been developed for the seemingly dissimilar processes leading to circulatory collapse and the shock state. ... and pressor agents. The response to exogenous corticosteroids is usually dramatic and potentially life-saving
Description : Night blindness is due to deficiency of vitamin: (a) A1 (b) A2 (c) D (d)B complex
Last Answer : (a) A1
Description : Infant i le convu ls ions due to lesser formation of gamma amino butyric acid from glutamic acid is seen in the deficiency of (A) Glutamate-dehydrogenase (B) Pyridoxine (C) Folic acid (D) Thiamin
Description : Neonatal tyrosinemia is due to deficiency of the enzyme: (A) p-Hydroxyphenylpyruvate hydroxylase (B) Fumarylacetoacetate hydrolase (C) Phenylalanine hydroxylase (D) Tyrosine dehydrogenase
Description : Albinism is due to deficiency of the enzyme: (A) Phenylalanine hydroxylase (B) Tyrosinase (C) p-Hydroxyphenylpyruvic acid oxidase (D) Tyrosine dehydrogenase
Description : Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase
Description : Acute hemolytic anemia in person’s sensitive to the Fava beans is due to the deficiency of the enzyme: (A) Pyruvate dehydrogenase (B) G-6-PD (C) Aconitase (D) Transketolase
Description : Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme ... PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin
Description : The antibiotic which has a structure similar to the amino acyl end of tRNA tyrosine is (A) Actinomycin d (B) Streptomycin (C) Puromycin (D) Mitomycin c