Description : Injury to adrenal cortex is not likely to affect the secretion of which one of the following? (a) Aldosterone (b) Both androstenedione and dehydroepiandrosterone (c) Adrenaline (d) Cortisol
Last Answer : (c) Adrenaline
Description : Which of the following hormones is considered a glucocorticoid? A) aldosterone B) insulin C) thyroxin D) cortisol E) parathyroid hormone
Last Answer : D) cortisol
Description : The major mineralcorticoid is (A) Hydrocortisone (B) Aldosterone (C) Aldactone A (D) Androstenedione
Last Answer : Answer : C
Description : Cortisol is a (A) Glucocorticoid (B) Mineralocorticoid (C) Androgen (D) Estrogen
Last Answer : Answer : B
Description : A middle aged female presented with following symptoms - Hirsutism, fragility of skin, with easy bruising, broad purplish striae and signs of proximal myopathy. The first step in ... Exclude exogenous Glucocorticoid use 3) Advice plasma ACTH estimation 4) Advice dexamethasone overnight test
Last Answer : Correct Answer: 2) Exclude exogenous Glucocorticoid use
Description : Increased reabsorption of water from the kidney is the major consequence of which of the following hormones? (A) Cortisol (B) Insulin (C) Vasopressin (D) Aldosterone
Description : Which of the following hormone is not under the control of ACTH? (A) Aldosterone (B) Cortisol (C) Corticosterone (D) Deoxycorticosterone
Last Answer : Answer : A
Description : The most potent hormone concerned with the retention of sodium in the body is (A) Cortisone (B) Aldosterone (C) Corticosterone (D) Cortisol
Description : Spironolactone is an antagonist of (A) Cortisol (B) Hydrocortisone (C) Aldosterone (D) Testosterone
Description : A common intermediate in the synthesis of cortisol and aldosterone is (A) Progesterone (B) Testosterone (C) Estradiol (D) None of these
Description : Increased reabsorption of water from the kidney is the major consequence of the secretion of the hormone? (A) Cortisol (B) Insulin (C) Vasopressin (D) Aldosterone
Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis
Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained
Description : The following are true about the hormones secreted by the adrenal cortex: a. zona fasciculata secretes cortisol b. zona glomerulosa secretes aldosterone c. secretion of aldosterone is stimulated by ACTH d. all
Last Answer : all
Description : Which hormone possesses anti-insulin effect? (a) Cortisol (b) Calcitonin (c) Oxytocin (d) Aldosterone
Last Answer : (a) Cortisol
Description : Which hormone will decrease blood glucose levels? A) thyroxin B) aldosterone C) cortisol D) insulin E) glucagon
Last Answer : D) insulin
Description : Which hormone will increase blood glucose levels? A) thyroxin B) aldosterone C) cortisol D) insulin E) calcitonin
Last Answer : C) cortisol
Description : The level of sodium in the blood is regulated by the secretion of A) oxytocin. B) insulin. C) cortisol. D) aldosterone. E) ACTH.
Last Answer : D) aldosterone.
Description : Which of the following hormones require iodine? A) thyroxin B) aldosterone C) parathyroid hormone D) insulin E) cortisol
Last Answer : A) thyroxin
Description : An androgen which is more powerful than testosterone is (A) Androstenedione (B) Dihydrotestosterone (C) Androsterone (D) Epiandrosterone
Description : The enzyme catalyzing conversion of androstenedione to testosterone is a (A) Oxygenase (B) Dehydrogenase (C) Isomerase (D) Decarboxylase
Description : In the biosynthesis of testosterone the rate limiting step is conversion of (A) Cholesterol to pregnenolone (B) Pregnenolone to progesterone (C) Progesterone to 17 α-hydroxy progesterone (D) 17 α-Hydroxy progesterone to androstenedione
Description : 3-β-Hydroxysteroid dehydrogenase and ∆5,4 isomerase catalyse the conversion of the weak androgen DHEA to (A) Androstenedione (B) Testosterone (C) Progesterone (D) Estrone
Description : The defect in adrenal cortex responsible for lack of glucocorticoids and mineralcorticoids is (A) Androstenedione deficiency (B) 17 α -OH progesterone deficiency (C) C-21 hydroxylase deficiency (D) Testosterone deficiency HORMONE METABOLISM 209
Description : Phosphorylated IRS-1 activates GRB-2 which is (A) G-protein receptor binding protein-2 (B) Growth factor receptor binding protein-2 (C) Growth hormone receptor binding protein-2 (D) Glucocorticoid receptor binding protein-2 226 MCQs IN BIOCHEMISTRY
Description : The predominant action of plasma is (A) HCO3– (B) Cl– (C) HPO4– – (D) SO4 – –
Description : The predominant cation of plasma is (A) Na+ (B) K+ (C) Ca+ (D) Mg++
Description : Predominant form of storage: (A) Carbohydrates (B) Fats (C) Lipids (D) Both (B) and (C)
Last Answer : Answer : D
Description : Predominant fatty acids in meat are (A) Saturated (B) Monounsaturated (C) Polyunsaturated (D) Mono and poly-unsaturated
Description : The predominant form of glucose in solution is (A) Acyclic form (B) Hydrated acyclic form (C) Glucofuranose (D) Glucopyranose
Last Answer : D
Description : Which of the following is noted in cushing’s syndrome, a tumor associated disease of the adrenal cortex? (A) Decreased production of epinephrine (B) Excessive production of epinephrine (C) Excessive production of vasopressin (D) Excessive production of cortisol
Description : A common intermediate in the synthesis of estrogens is (A) Cortisol (B) Andostenedione (C) Corticosterone (D) 11-Deoxycorticosterone
Description : Regulation of ACTH secretion occurs through (A) Corticotropin releasing hormone (CRH) and corticotropin release inhibiting hormone (CRIH) of hypothalamus (B) Feedback inhibition by cortisol (C) CRH and feedback inhibition by cortisol (D) CRIH and feedback inhibition by cortisol
Description : In the resting state plasma concentration of cortisol is (A) 0.4–2.0 µg/100 ml (B) 2.0–4.0 µg/100 ml (C) 5.0–15.0 µg/100 ml (D) 18.0–25.0 µg/100 ml
Description : Cortisol is synthesized in (A) Zona fasiculata (B) Zona glomerulosa (C) Zona reticularis (D) Chromaffin cells
Description : A specific cortisol binding protein, transcortin is a (A) Albumin (B) α1-Globulin (C) α2-Globulin (D) β-Globulin
Description : In Cushing’s syndrome-a tumour associated disease of adrenal cortex, there is (A) Decreased epinephrine production (B) Excessive cortisol production (C) Excessive epinephrine production (D) Decreased cortsoil production
Description : A characteristic feature of marasmus is (A) Severe hypoalbuminemia (B) Normal epinephrine level (C) Mild muscle wasting (D) Low insulin and high cortisol level
Description : Which of the following hormones is not involved in carbohydrate metabolism? (A) Cortisol (B) ACTH (C) Glucogen (D) Vasopressin
Description : Which of the following techniques would be most useful in the differential diagnosis between ectopic Cushing's syndrome and pituitary dependent Cushing's disease. 1) Urine free cortisol 2) ... Dexamethasone suppression test 3) ACTH concentrations 4) Inferior petrosal sinus sampling 5) CRF test
Last Answer : Answers-4 Inferior petrosal sinus sampling with an elevated central ACTH concentration compared with the peripheral value is the most valuable test in the differential diagnosis of either Cushing's disease or ectopic Cushing's syndrome. The other tests are far less useful in comparison.
Description : What is the difference between mineralocorticoid and glucocorticoid hormones? -Biology
Last Answer : answer:
Description : Main glucocorticoid hormone responsible for carbohydrate metabolism is
Last Answer : Main glucocorticoid hormone responsible for carbohydrate metabolism is
Description : Interleukin-6 is recognized as the cytokine primarily responsible for the alteration in hepatic protein synthesis recognized as the acute phase response. Which of the following statement(s) is/are true ... physiologic role of acute phase proteins are to reduce the systemic effects of tissue damage
Last Answer : Answer: c, d IL-6 is now recognized at the cytokine primarily responsible for the alteration in hepatic synthesis recognized as the acute phase response. Glucocorticoid hormones augment ... that generally inhibit the tissue destruction that is associated with the local initiation of inflammation
Description : To be a useful inhaled glucocorticoid the drug should have (a) High oral bioavailability (b) Low oral bioavailability (c) Additional bronchodilator activity (d) Prodrug character
Last Answer : Ans: B
Description : Which of the following bones is affected more by glucocorticoid induced osteoporosis? (a) Femur (b) Humerus (c) Radius (d) Lumber vertebra
Last Answer : Ans: D
Description : Glucocorticoid causes an increase of: a. red blood cells b. lymphocytes c. eosinophils d. platelets
Last Answer : platelets
Description : The effects of glucocorticoid hormones include: a. increase hepatic glycogen synthesis b. decrease glucose uptake by the adipose tissue c. decrease hepatic gluconeogesis d. increase protein synthesis in the skeletal muscles
Last Answer : . increase hepatic glycogen synthesis
Description : G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins
Last Answer : are activated by the binding of an extracellular ligand to a membrane receptor
Description : Mifepristone possesses the following activities: A. Potent antiprogestin + weak androgenic B. Potent antiprogestin + weak antiglucocorticoid C. Potent antiestrogenic + weak antiprogestin D. Potent antiestrogenic + weak glucocorticoid
Last Answer : Mifepristone possesses the following activities: A. Potent antiprogestin + weak androgenic B. Potent antiprogestin + weak antiglucocorticoid C. Potent antiestrogenic + weak antiprogestin D. Potent antiestrogenic + weak glucocorticoid
Description : Which of the following bones is affected more by glucocorticoid induced osteoporosis: A. Lumber vertebra B. Humerus C. Radius D. Femur
Last Answer : A. Lumber vertebra
Description : The following glucocorticoid has significant mineralocorticoid activity also: A. Hydrocortisone B. Triamcinolone C. Dexamethasone D. Betamethasone
Last Answer : A. Hydrocortisone