Histamine is involved as a mediator in the following pathological condition: A. Delayed hypersensitivity reaction B. Inflammation C. Carcinoid syndrome D. Variant angina

Histamine is involved as a mediator in the following pathological condition: A. Delayed hypersensitivity reaction B. Inflammation C. Carcinoid syndrome D. Variant angina
by

1 Answer

Answer :

B. Inflammation
by

Related questions

Histamine is involved as a mediator in the following pathological condition: A. Delayed hypersensitivity reaction B. Inflammation C. Carcinoid syndrome D. Variant angina

Description : Histamine is involved as a mediator in the following pathological condition: A. Delayed hypersensitivity reaction B. Inflammation C. Carcinoid syndrome D. Variant angina

Last Answer : B. Inflammation

The following statement about histamine is not correct: A. It is the sole mediator of immediate hypersensitivity reaction B. It plays no role in delayed hypersensitivity reaction C. It serves as a neurotransmitter in the brain D. All types of histamine receptors are G protein coupled receptors

Description : The following statement about histamine is not correct: A. It is the sole mediator of immediate hypersensitivity reaction B. It plays no role in delayed hypersensitivity reaction C. It serves as a neurotransmitter in the brain D. All types of histamine receptors are G protein coupled receptors

Last Answer : A. It is the sole mediator of immediate hypersensitivity reaction

The following statement about histamine is not correct: A. It is the sole mediator of immediate hypersensitivity reaction B. It plays no role in delayed hypersensitivity reaction C. It serves as a neurotransmitter in the brain D. All types of histamine receptors are G protein coupled receptors

Description : The following statement about histamine is not correct: A. It is the sole mediator of immediate hypersensitivity reaction B. It plays no role in delayed hypersensitivity reaction C. It serves as a neurotransmitter in the brain D. All types of histamine receptors are G protein coupled receptors

Last Answer : A. It is the sole mediator of immediate hypersensitivity reaction

Histamine is involved as a mediator in the following pathological conditon (a) Cocaine (b) Dibucaine (c) Lidocaine (d) Procaine

Description : Histamine is involved as a mediator in the following pathological conditon (a) Cocaine (b) Dibucaine (c) Lidocaine (d) Procaine

Last Answer : Ans: B

The following are true about cell-mediated immunity: a. antigen-specific function is the role of the T-lymphocytes b. cell-mediated immunity can activate the complement system c. it is responsible for the delayed hypersensitivity reaction. d. Gamma interferon is an important mediator of B-cell activation.

Description : The following are true about cell-mediated immunity: a. antigen-specific function is the role of the T-lymphocytes b. cell-mediated immunity can activate the complement system c. it is ... the delayed hypersensitivity reaction. d. Gamma interferon is an important mediator of B-cell activation.

Last Answer : cell-mediated immunity can activate the complement system

In carcinoid syndrome the argentaffin tissue of the abdominal cavity overproduce (A) Serotonin (B) Histamine (C) Tryptamine (D) Tyrosine

Description : In carcinoid syndrome the argentaffin tissue of the abdominal cavity overproduce (A) Serotonin (B) Histamine (C) Tryptamine (D) Tyrosine

Last Answer : Answer : A

A drug which preferentially dilates autoregulatory coronary arterioles with little effect on large conducting vessels is likely to: A. Evoke coronary steal phenomenon B. Mitigate classical angina but not variant angina C. Decrease total coronary blood flow in healthy subjects D. Avert ECG changes of ischaemia

Description : A drug which preferentially dilates autoregulatory coronary arterioles with little effect on large conducting vessels is likely to: A. Evoke coronary steal phenomenon B. Mitigate classical angina but not ... . Decrease total coronary blood flow in healthy subjects D. Avert ECG changes of ischaemia

Last Answer : A. Evoke coronary steal phenomenon

Following mediators are involved in acute inflammation except (a) Histamine (b) Leukotrienes (c) Interferons (d) Bradykinin

Description : Following mediators are involved in acute inflammation except (a) Histamine (b) Leukotrienes (c) Interferons (d) Bradykinin

Last Answer : Ans: C

Which of the following statements concerning perioperative nutrition is true concerning the above-described patient? a. Since the patient’s weight had been stable with no preoperative nutritional deficit, 5% dextrose intravenous solutions are adequate for the initial postoperative source of nutrition b. Preoperative immunologic status should be determined including total peripheral lymphocyte count and delayed hypersensitivity reaction to determine skin-test response to common antigens c. Routine postoperative fluid administration with intravenous 5% glucose solutions can provide the calories to meet basal energy requirements d. A jejunal feeding catheter should be placed at the time of surgery for postoperative enteral feeding

Description : Which of the following statements concerning perioperative nutrition is true concerning the above-described patient? a. Since the patient's weight had been stable with no preoperative nutritional deficit ... feeding catheter should be placed at the time of surgery for postoperative enteral feeding

Last Answer : Answer: a Most patients undergoing elective operations are adequately nourished. Unless the patient has suffered significant preoperative malnutrition, characterized by weight loss greater than ... gastrointestinal surgery, this technique would not appear indicated in the patient described above

In which of the following cell mediated immunity (CMI) participates? A.Delayed hypersensitivity reaction B.Graft versus host reaction C.Allograft rejection D.All of the above

Description : In which of the following cell mediated immunity (CMI) participates? A.Delayed hypersensitivity reaction B.Graft versus host reaction C.Allograft rejection D.All of the above

Last Answer : D.All of the above

In which of the following cell mediated immunity (CMI) participates? A.Delayed hypersensitivity reaction B.Graft versus host reaction C.Allograft rejection D.All of the above

Description : In which of the following cell mediated immunity (CMI) participates? A.Delayed hypersensitivity reaction B.Graft versus host reaction C.Allograft rejection D.All of the above

Last Answer : .All of the above

Which of the following statements describes the clinical manifestations of a delayed hypersensitivity (type IV) allergic reaction to latex? a) Signs and symptoms are localized to the area of exposure, usually the back of the hands. Clinical manifestations of a delayed hypersensitivity reaction are localized to the area of exposure.

Description : Which of the following statements describes the clinical manifestations of a delayed hypersensitivity (type IV) allergic reaction to latex? a) Signs and symptoms are localized to the area of ... minutes after exposure to latex, an immediate hypersensitivity (type I) allergic reaction has occurred.

Last Answer : a) Signs and symptoms are localized to the area of exposure, usually the back of the hands. Clinical manifestations of a delayed hypersensitivity reaction are localized to the area of exposure.

Following is an example of preformed and not lipid derived mast cell mediator of inflammatory process (a) LTC4 (b) PGD2 (c) PAF (d) Histamine

Description : Following is an example of preformed and not lipid derived mast cell mediator of inflammatory process (a) LTC4 (b) PGD2 (c) PAF (d) Histamine

Last Answer : Ans: D

The most important preformed mediator of allergic reactions is/are a. Prostaglandin b. Interleukin c. Histamine d. Leukotrienes

Description : The most important preformed mediator of allergic reactions is/are a. Prostaglandin b. Interleukin c. Histamine d. Leukotrienes

Last Answer : c. Histamine

Urinary excretion of vanillyl madelic acid is increased in (A) Phaeochromocytoma (B) Cushing’s syndrome (C) Carcinoid syndrome (D) Aldosteronism

Description : Urinary excretion of vanillyl madelic acid is increased in (A) Phaeochromocytoma (B) Cushing’s syndrome (C) Carcinoid syndrome (D) Aldosteronism

Last Answer : Answer : A

Aspirin in small doses (50 to 150 mg per day) (a) Is of benefit in patients of unstable angina (b) Has thrombolytic action (c) PREFerentially inhibits prostacyclin synthetase enzyme (d) MAY Alleviate need for Verapamil in variant angina

Description : Aspirin in small doses (50 to 150 mg per day) (a) Is of benefit in patients of unstable angina (b) Has thrombolytic action (c) PREFerentially inhibits prostacyclin synthetase enzyme (d) MAY Alleviate need for Verapamil in variant angina

Last Answer : Ans: A

Exertion–induced angina, which is relieved by rest, nitroglycerin, or both, is referred to as (a) Prinzmetal’s angina (b) Unstable angina (c) Classic angina (d) Variant angina (e) Preinfarction angina

Description : Exertion–induced angina, which is relieved by rest, nitroglycerin, or both, is referred to as (a) Prinzmetal’s angina (b) Unstable angina (c) Classic angina (d) Variant angina (e) Preinfarction angina

Last Answer : Ans: C

The following factor is not involved in the causation of hypotension due to spinal anaesthesia: A. Histamine release B. Reduced sympathetic vasoconstrictor tone C. Decreased venous return from the lower limbs D. Bradycardia

Description : The following factor is not involved in the causation of hypotension due to spinal anaesthesia: A. Histamine release B. Reduced sympathetic vasoconstrictor tone C. Decreased venous return from the lower limbs D. Bradycardia

Last Answer : A. Histamine release

The most important receptor involved in cytotoxic drug induced vomiting is: A. Histamine H1 receptor B. Serotonin 5-HT3 receptor C. Dopamine D2 receptor D. Opioid μ receptor

Description : The most important receptor involved in cytotoxic drug induced vomiting is: A. Histamine H1 receptor B. Serotonin 5-HT3 receptor C. Dopamine D2 receptor D. Opioid μ receptor

Last Answer : B. Serotonin

An intradermal penicillin sensitivity test has been performed on a patient and found to be negative. This indicates that: A. Penicillin antibodies are not present in his body B. He will not develop any reaction when full dose of penicillin is injected C. He will not develop anaphylactic reaction when full dose of penicillin is injected D. He is unlikely to develop immediate type of hypersensitivity reaction when full dose of penicillin is injected

Description : An intradermal penicillin sensitivity test has been performed on a patient and found to be negative. This indicates that: A. Penicillin antibodies are not present in his body B. He will ... He is unlikely to develop immediate type of hypersensitivity reaction when full dose of penicillin is injected

Last Answer : D. He is unlikely to develop immediate type of hypersensitivity reaction when full dose of penicillin is injected

The most important reason for highly restricted use of penicillin G injections in present day therapeutics is its: A. Narrow spectrum of activity B. Potential to cause hypersensitivity reaction C. Short duration of action D. Neurotoxicity

Description : The most important reason for highly restricted use of penicillin G injections in present day therapeutics is its: A. Narrow spectrum of activity B. Potential to cause hypersensitivity reaction C. Short duration of action D. Neurotoxicity

Last Answer : B. Potential to cause hypersensitivity reaction

An immunologically mediated reaction to a drug producing stereotyped symptoms unrelated to its pharmacodynamic actions is: A. Hypersensitivity B. Supersensitivity C. Intolerance D. Idiosyncrasy

Description : An immunologically mediated reaction to a drug producing stereotyped symptoms unrelated to its pharmacodynamic actions is: A. Hypersensitivity B. Supersensitivity C. Intolerance D. Idiosyncrasy

Last Answer : A. Hypersensitivity

Low doses of aspirin prolong bleeding time by selectively inhibiting synthesis of the following mediator in the platelets: A. Thromboxane A2 B. 5-Hydroxytryptamine C. Platelet activating factor D. Prostacyclin

Description : Low doses of aspirin prolong bleeding time by selectively inhibiting synthesis of the following mediator in the platelets: A. Thromboxane A2 B. 5-Hydroxytryptamine C. Platelet activating factor D. Prostacyclin

Last Answer : A. Thromboxane

What is delayed hypersensitivity ?

Description : What is delayed hypersensitivity ?

Last Answer : We can recognize the Symptoms only days after exposure. This is delayed hypersensitivity (DTH).

In AIDS, the following abnormalities are seen: a. persistent lymphopenia b. decreased interleukin-2 production c. impaired delayed cutaneous hypersensitivity reactions d. all above

Description : In AIDS, the following abnormalities are seen: a. persistent lymphopenia b. decreased interleukin-2 production c. impaired delayed cutaneous hypersensitivity reactions d. all above

Last Answer : all above

Hashimoto disease and Graves‘ disease are similar in that both a. Affect the thyroid gland. b. Affect the red blood cells. c. Are forms of cellular hypersensitivity? d. Are accompanied by histamine release.

Description : Hashimoto disease and Graves‘ disease are similar in that both a. Affect the thyroid gland. b. Affect the red blood cells. c. Are forms of cellular hypersensitivity? d. Are accompanied by histamine release.

Last Answer : b. Affect the red blood cells.

During the course of a cellular hypersensitivity a. Antibodies react with antigens in tissues. b. Serotonin and histamine are released by cells. c. Immune complexes form on blood vessel surfacesd. A skin thickening called an induration may form..

Description : During the course of a cellular hypersensitivity a. Antibodies react with antigens in tissues. b. Serotonin and histamine are released by cells. c. Immune complexes form on blood vessel surfaces. d. A skin thickening called an induration may form.

Last Answer : b. Serotonin and histamine are released by cells.

The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine

Description : The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine

Last Answer : C. Morphine

The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine

Description : The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine

Last Answer : C. Morphine

Your patient is to receive a selective ß2 stimulant drug ß2 selective stimulant are often effective in (a) Angina due to coronary insufficiency (b) Asthma (c) Chronic heart failure (d) Delayed or insufficiently strong labor (e) All of the above

Description : Your patient is to receive a selective ß2 stimulant drug ß2 selective stimulant are often effective in (a) Angina due to coronary insufficiency (b) Asthma (c) Chronic heart failure (d) Delayed or insufficiently strong labor (e) All of the above

Last Answer : Ans: B

Beneficial effects of β-adrenoceptor blockers in CHF include the following except: A. Antagonism of ventricular wall stress enhancing action of sympathetic overactivity B. Antagonism of vasoconstriction due to sympathetic overactivity C. Prevention of pathological remodeling of ventricular myocardium D. Prevention of dangerous cardiac arrhythmias

Description : Beneficial effects of β-adrenoceptor blockers in CHF include the following except: A. Antagonism of ventricular wall stress enhancing action of sympathetic overactivity B. Antagonism ... Prevention of pathological remodeling of ventricular myocardium D. Prevention of dangerous cardiac arrhythmias

Last Answer : B. Antagonism of vasoconstriction due to sympathetic overactivity

Beneficial effect/effects of diuretics in CHF patients include the following: A. Symptomatic relief B. Regression of pathological changes C. Prolongation of life expectancy D. Both ‘A’ and ‘C’

Description : Beneficial effect/effects of diuretics in CHF patients include the following: A. Symptomatic relief B. Regression of pathological changes C. Prolongation of life expectancy D. Both ‘A’ and ‘C’

Last Answer : A. Symptomatic relief

Digoxin affords the following benefit/benefits in CHF: A. Restores cardiac compensation and relieves symptoms B. Reverses the pathological changes of CHF C. Prolongs survival of CHF patients D. Both ‘A’ and ‘B’ are correc

Description : Digoxin affords the following benefit/benefits in CHF: A. Restores cardiac compensation and relieves symptoms B. Reverses the pathological changes of CHF C. Prolongs survival of CHF patients D. Both ‘A’ and ‘B’ are correc

Last Answer : A. Restores cardiac compensation and relieves symptoms

Which of the following statements regarding cytokines is incorrect? A. Cytokines act directly on target cells and may potentiate the actions of one another. B. Interleukin 1 (IL-1) is a major proinflammatory mediator with multiple effects, including regulation of skeletal muscle proteolysis in patients with sepsis or significant injury. C. Platelet-activating factor (PAF) is a major cytokine that results in platelet aggregation, bronchoconstriction, and increased vascular permeability. D. Tumor necrosis factor alpha (TNF-a), despite its short plasma half-life, appears to be a principal mediator in the evolution of sepsis and the multiple organ dysfunction syndrome because of its multiple actions and the secondary cascades that it stimulates.

Description : Which of the following statements regarding cytokines is incorrect? A. Cytokines act directly on target cells and may potentiate the actions of one another. B. Interleukin 1 (IL-1) ... organ dysfunction syndrome because of its multiple actions and the secondary cascades that it stimulates.

Last Answer : Answer: C DISCUSSION: Cytokines are soluble peptide molecules that are synthesized and secreted by a number of cell types in response to injury, inflammation, and infection. Cytokines, which ... is thought to play a central role in the stress response, particularly in response to endotoxemia

4 Choose the correct statement about the role of opioid antimotility drugs in the management of diarrhoeas: A. They are used to control diarrhoea irrespective of its etiology B. They should be used only as a short-term measure after ensuring that enteroinvasive organisms are not involved C. They are used as adjuvants to antimicrobial therapy of diarrhoea D. They are the drugs of choice in irritable bowel syndrome diarrhoea

Description : 4 Choose the correct statement about the role of opioid antimotility drugs in the management of diarrhoeas: A. They are used to control diarrhoea irrespective of its etiology B. They should ... antimicrobial therapy of diarrhoea D. They are the drugs of choice in irritable bowel syndrome diarrhoea

Last Answer : B. They should be used only as a short-term measure after ensuring that enteroinvasive organisms are not involved

Megaloblastic anaemia developing under the following condition is due entirely to folate deficiency not associated with vitamin B12 deficiency: A. Malnutrition B. Blind loop syndrome C. Phenytoin therapy D. Pregnancy

Description : Megaloblastic anaemia developing under the following condition is due entirely to folate deficiency not associated with vitamin B12 deficiency: A. Malnutrition B. Blind loop syndrome C. Phenytoin therapy D. Pregnancy

Last Answer : C. Phenytoin therapy

Bisphosphonates are indicated in the following condition: A. Organophosphate poisoning B. Dementia C. Steven’s Johnson syndrome D. Osteoporosis

Description : Bisphosphonates are indicated in the following condition: A. Organophosphate poisoning B. Dementia C. Steven’s Johnson syndrome D. Osteoporosis

Last Answer : D. Osteoporosis

The effect of propranolol on heart rate is least marked under the following condition: A. Physical exercise B. Rest C. Anxiety D. Sick sinus syndrome

Description : The effect of propranolol on heart rate is least marked under the following condition: A. Physical exercise B. Rest C. Anxiety D. Sick sinus syndrome

Last Answer : B. Rest

The effect of propranolol on heart rate is least marked under the following condition: A. Physical exercise B. Rest C. Anxiety D. Sick sinus syndrome

Description : The effect of propranolol on heart rate is least marked under the following condition: A. Physical exercise B. Rest C. Anxiety D. Sick sinus syndrome

Last Answer : B. Rest

Polymorphonuclear neutrophil granulocytes A A. are important cells in bacterial infections B. play a role in inflammation by releasing histamine C. are important cells in neoplastic conditions D. play an important role in viral infections

Description : Polymorphonuclear neutrophil granulocytes A A. are important cells in bacterial infections B. play a role in inflammation by releasing histamine C. are important cells in neoplastic conditions D. play an important role in viral infections

Last Answer : are important cells in bacterial infections

Biological response modifiers like GM-CSF are used in conjunction with anticancer drugs for the following purpose(s): A. To enhance antitumour activity of the drug B. To prevent hypersensitivity reactions to the drug C. To hasten recovery from drug induced myelosuppression D. Both ‘A’ and ‘C’ are correct

Description : Biological response modifiers like GM-CSF are used in conjunction with anticancer drugs for the following purpose(s): A. To enhance antitumour activity of the drug B. To prevent hypersensitivity reactions to ... . To hasten recovery from drug induced myelosuppression D. Both A' and C' are correct

Last Answer : C. To hasten recovery from drug induced myelosuppressio

Semisynthetic penicillins developed so far have overcome the following drawbacks of benzylpenicillin except: A. Lack of efficacy against gram negative bacilli B. Susceptibility to bacterial penicillinase C. Inactivation by gastric acid D. Potential to cause hypersensitivity reactions

Description : Semisynthetic penicillins developed so far have overcome the following drawbacks of benzylpenicillin except: A. Lack of efficacy against gram negative bacilli B. Susceptibility to bacterial penicillinase C. Inactivation by gastric acid D. Potential to cause hypersensitivity reactions

Last Answer : D. Potential to cause hypersensitivity reactions

Indications for the use of antiplatelet drugs include the following except: A. Secondary prophylaxis of myocardial infarction B. Unstable angina pectoris C. Disseminated intravascular coagulation D. Stroke prevention in patients with transient ischaemic attacks

Description : Indications for the use of antiplatelet drugs include the following except: A. Secondary prophylaxis of myocardial infarction B. Unstable angina pectoris C. Disseminated intravascular coagulation D. Stroke prevention in patients with transient ischaemic attacks

Last Answer : C. Disseminated intravascular coagulation

Used alone the following antihypertensive drug tends to increase cardiac work and can precipitate angina: A. Clonidine B. Hydralazine C. Captopril D. Prazosin

Description : Used alone the following antihypertensive drug tends to increase cardiac work and can precipitate angina: A. Clonidine B. Hydralazine C. Captopril D. Prazosin

Last Answer : B. Hydralazine

A 40-year-old politician suffered from attacks of chest pain diagnosed as angina pectoris. He had a tense personality, resting heart rate was 96/min, blood pressure 170/104 mm Hg, but blood sugar level and lipid profile were normal. Select the most suitable antihypertensive for initial therapy in his case: A. Nifedipine B. Hydrochlorothiazide C. Atenolol D. Methyldopa

Description : A 40-year-old politician suffered from attacks of chest pain diagnosed as angina pectoris. He had a tense personality, resting heart rate was 96/min, blood pressure 170/104 mm Hg, but ... antihypertensive for initial therapy in his case: A. Nifedipine B. Hydrochlorothiazide C. Atenolol D. Methyldopa

Last Answer : C. Atenolol

Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris, because: A. They antagonise each other’s side effects B. Nitrates primarily reduce preload while calcium channel blockers primarily reduce after-load C. Nitrates increase coronary flow while calcium channel blockers reduce ca

Description : Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris, because: A. They antagonise each other's side effects B. Nitrates primarily ... primarily reduce after-load C. Nitrates increase coronary flow while calcium channel blockers reduce ca

Last Answer : B. Nitrates primarily reduce preload while calcium channel blockers primarily reduce after-load

Propranolol should not be prescribed for a patient of angina pectoris who is already receiving: A. Nifedipine B. Felodipine C. Verapamil D. Isosorbide mononitrate

Description : Propranolol should not be prescribed for a patient of angina pectoris who is already receiving: A. Nifedipine B. Felodipine C. Verapamil D. Isosorbide mononitrate

Last Answer : C. Verapami

he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect C. It can inhibit insulin release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori

Description : he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to ... release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori

Last Answer : B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect

Which of the following drugs is most likely to accentuate varient (Prinzmetal) angina: A. Propranolol B. Atenolol C. Verapamil D. Dipyridamole

Description : Which of the following drugs is most likely to accentuate varient (Prinzmetal) angina: A. Propranolol B. Atenolol C. Verapamil D. Dipyridamole

Last Answer : A. Propranolol