During compensation of respiratory alkalosis, all the following changes occur except (A) Decreased secretion of hydrogen ions by renal tubules (B) Increased excretion of sodium in urine (C) Increased excretion of bicarbonate in urine (D) Increased excretion of ammonia in urine

During compensation of respiratory alkalosis, all the following changes occur except (A) Decreased secretion of hydrogen ions by renal tubules (B) Increased excretion of sodium in urine (C) Increased excretion of bicarbonate in urine (D) Increased excretion of ammonia in urine
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All the following statements about renal tubular acidosis are correct except (A) Renal tubules may be unable to reabsorb bicarbonate (B) Renal tubules may be unable to secrete hydrogen ions (C) Plasma chloride is elevated (D) Anion gap is decreased

Description : All the following statements about renal tubular acidosis are correct except (A) Renal tubules may be unable to reabsorb bicarbonate (B) Renal tubules may be unable to secrete hydrogen ions (C) Plasma chloride is elevated (D) Anion gap is decreased

Last Answer : Answer : D

Which of the following statements about respiratory acidosis are true? A. Compensation occurs by a shift of chloride out of the red blood cells. B. Renal compensation occurs rapidly. C. Retention of bicarbonate and increased ammonia formation are normal compensatory mechanisms. D. Narcotic administration is an unusual cause of respiratory acidosis. E. The ratio of bicarbonate to carbonic acid is less than 20:1.

Description : Which of the following statements about respiratory acidosis are true? A. Compensation occurs by a shift of chloride out of the red blood cells. B. Renal compensation occurs rapidly. C. Retention of ... of respiratory acidosis. E. The ratio of bicarbonate to carbonic acid is less than 20:1.

Last Answer : Answer: CE DISCUSSION: Renal compensation for acute hypoventilation is relatively slow. Depression of the respiratory center by morphine can lead to respiratory acidosis. Renal retention of bicarbonate, ... into red cells combine to increase the ratio of bicarbonate to carbonic acid to 20:1

The following are true about aldosterone: a. it is secreted by the adrenal medulla b. its secretion is stimulated by decreased blood volume c. it stimulates active reabsorption of sodium in the distal renal tubules. d. it causes increased secretion of potassium by the distal renal tubules.

Description : The following are true about aldosterone: a. it is secreted by the adrenal medulla b. its secretion is stimulated by decreased blood volume c. it stimulates active reabsorption of sodium in the distal renal tubules. d. it causes increased secretion of potassium by the distal renal tubules.

Last Answer : it causes increased secretion of potassium by the distal renal tubules.

If the body undergoes alkalosis the respiratory center located in the medulla gets the information and induces the lowering of the respiratory frequency. The reduction of the respiratory frequency makes the body retain more carbon dioxide and to shift the equilibrium of the formation of bicarbonate towards the production of more hydrogen ions and thus the blood pH lowers.

Description : If the body undergoes alkalosis the respiratory center located in the medulla gets the information and induces the lowering of the respiratory frequency. The reduction of the respiratory frequency makes ... of bicarbonate towards the production of more hydrogen ions and thus the blood pH lowers.

Last Answer : What is the difference between respiratory acidosis and metabolic acidosis and what is the difference between respiratory alkalosis and metabolic alkalosis?

All of the following occur in orotic aciduria except (A) Increased synthesis of pyrimidine nucleotides (B) Increased excretion of orotic acid in urine (C) Decreased synthesis of cytidine triphosphate (D) Retardation of growth

Description : All of the following occur in orotic aciduria except (A) Increased synthesis of pyrimidine nucleotides (B) Increased excretion of orotic acid in urine (C) Decreased synthesis of cytidine triphosphate (D) Retardation of growth

Last Answer : Answer : A

All the following changes in blood chemistry can occur in severe diarrhoea except (A) Decreased pH (B) Decreased bicarbonate (C) Increased pCO2 (D) Increased chloride WATER AND ELECTROLYTE BALANCE 287

Description : All the following changes in blood chemistry can occur in severe diarrhoea except (A) Decreased pH (B) Decreased bicarbonate (C) Increased pCO2 (D) Increased chloride WATER AND ELECTROLYTE BALANCE 287

Last Answer : Answer : C

Plasma bicarbonate is decreased in (A) Respiratory alkalosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Metabolic acidosis

Description : Plasma bicarbonate is decreased in (A) Respiratory alkalosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Metabolic acidosis

Last Answer : Answer : D

The following occur in the proximal tubules of the nephron: a. reabsorption of all glucose b. reabsorption of most water c. secretion of bicarbonate d. active reabsorption of sodium

Description : The following occur in the proximal tubules of the nephron: a. reabsorption of all glucose b. reabsorption of most water c. secretion of bicarbonate d. active reabsorption of sodium

Last Answer : active reabsorption of sodium

Blood chemistry shows the following changes in compensated respiratory acidosis: (A) Increased pCO2 (B) Increased bicarbonate (C) Decreased chloride (D) All of these

Description : Blood chemistry shows the following changes in compensated respiratory acidosis: (A) Increased pCO2 (B) Increased bicarbonate (C) Decreased chloride (D) All of these

Last Answer : Answer : D

Plasma bicarbonate is increased in (A) Respiratory alkalosis (B) Metabolic alkalosis (C) Respiratory acidosis (D) Metabolic acidosis

Description : Plasma bicarbonate is increased in (A) Respiratory alkalosis (B) Metabolic alkalosis (C) Respiratory acidosis (D) Metabolic acidosis

Last Answer : Answer : B

Which of the following features are present in blood chemistry in uncompensated metabolic alkalosis except? (A) Increased pH (B) Increased bicarbonate (C) Normal chloride (D) Normal pCO2

Description : Which of the following features are present in blood chemistry in uncompensated metabolic alkalosis except? (A) Increased pH (B) Increased bicarbonate (C) Normal chloride (D) Normal pCO2

Last Answer : Answer : D

An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

Description : An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

Last Answer : Answer : D

The primary event in respiratory alkalosis is (A) Rise in pH (B) Decrease in pCO2 (C) Increase in plasma bicarbonate (D) Decrease in plasma chloride

Description : The primary event in respiratory alkalosis is (A) Rise in pH (B) Decrease in pCO2 (C) Increase in plasma bicarbonate (D) Decrease in plasma chloride

Last Answer : Answer : B

Respiratory alkalosis is caused by (A) An increase in carbonic acid fraction (B) A decrease in bicarbonic fraction (C) A decrease in the carbonic acid fraction (D) An increase in bicarbonate fraction

Description : Respiratory alkalosis is caused by (A) An increase in carbonic acid fraction (B) A decrease in bicarbonic fraction (C) A decrease in the carbonic acid fraction (D) An increase in bicarbonate fraction

Last Answer : Answer : C

A 45-year-old solicitor had an onset of severe, crushing, substernal chest pain while attending a football match. He collapsed on his way to the car. Bystander Cardiorespiratory Resuscitation was begun immediately and continued until arrival in Casualty where an endotracheal tube was inserted and ventilation was maintained on 100% oxygen. Investigations revealed: pH 7.13 PaO2 560 mmHg PaCO2 18 mmHg Bicarbonate 5.8 SaO2 98% Based on these laboratory values, which of the following statements best describes his current pathophysiology? 1) He is demonstrating a primary respiratory alkalosis 2) He probably developed a large right to left intracardiac shunt 3) His anion gap is probably normal 4) His oxyhemoglobin curve is shifted to the left 5) His pulmonary artery pressure is probably elevated

Description : A 45-year-old solicitor had an onset of severe, crushing, substernal chest pain while attending a football match. He collapsed on his way to the car. Bystander Cardiorespiratory Resuscitation ... His oxyhemoglobin curve is shifted to the left 5) His pulmonary artery pressure is probably elevated

Last Answer : Answers-5 This young patient with severe central chest pain has probably arrested due to myocardial infarction and arrhythmia. His gases reveal high PO2 following 100% O2 but severe acidosis ... no left to right shunting and high pulmonary pressures would be expected after this arrest scenario.

Renal glycosuria occurs due to (A) Increased filtration of glucose in glomeruli (B) Increased secretion of glucose by renal tubular cells (C) Decreased reabsorption of glucose by renal tubular cells (D) Increased conversion of glycogen into glucose in tubular cells

Description : Renal glycosuria occurs due to (A) Increased filtration of glucose in glomeruli (B) Increased secretion of glucose by renal tubular cells (C) Decreased reabsorption of glucose by renal tubular cells (D) Increased conversion of glycogen into glucose in tubular cells

Last Answer : Answer : D

Respiratory alkalosis occurs in (A) Hysterical hyperventilation (B) Depression of respiratory centre (C) Renal diseases (D) Loss of intestinal fluids

Description : Respiratory alkalosis occurs in (A) Hysterical hyperventilation (B) Depression of respiratory centre (C) Renal diseases (D) Loss of intestinal fluids

Last Answer : Answer : A

All the following statements about phenylketonuria are correct except (A) Phenylalanine cannot be converted into tyrosine (B) Urinary excretion of phenylpyruvate and phenyllactate is increased (C) It can be controlled by giving a lowphenylalanine diet (D) It leads to decreased synthesis of thyroid hormones, catecholamines and melanin

Description : All the following statements about phenylketonuria are correct except (A) Phenylalanine cannot be converted into tyrosine (B) Urinary excretion of phenylpyruvate and phenyllactate is increased (C) It ... diet (D) It leads to decreased synthesis of thyroid hormones, catecholamines and melanin

Last Answer : Answer : D

If the body experiences acidosis the respiratory center located in the medulla gets the information and induces the increase of the respiratory frequency. The increment of the respiratory frequency makes the body eliminate more carbon dioxide and to shift the equilibrium of the formation of bicarbonate towards the spending of more hydrogen ions and thus the blood pH raises.

Description : If the body experiences acidosis the respiratory center located in the medulla gets the information and induces the increase of the respiratory frequency. The increment of the respiratory frequency makes the ... of bicarbonate towards the spending of more hydrogen ions and thus the blood pH raises.

Last Answer : How does the breathing process correct alkalosis?

Metabolic effects that generally attend antiinflammatory doses of aspirin include the following except: A. Increased CO2 production B. Hepatic glycogen depletion C. Metabolic acidosis D. Compensated respiratory alkalosis

Description : Metabolic effects that generally attend antiinflammatory doses of aspirin include the following except: A. Increased CO2 production B. Hepatic glycogen depletion C. Metabolic acidosis D. Compensated respiratory alkalosis

Last Answer : C. Metabolic acidosis

ADH (A) Reabsorbs water from renal tubules (B) Excretes water from renal tubules (C) Excretes hypotonic urine (D) Causes low specific gravity of urine 210 MCQs IN BIOCHEMISTRY

Description : ADH (A) Reabsorbs water from renal tubules (B) Excretes water from renal tubules (C) Excretes hypotonic urine (D) Causes low specific gravity of urine 210 MCQs IN BIOCHEMISTRY

Last Answer : Answer : A

Metabolic alkalosis can occur in (A) Severe diarrhoea (B) Renal failure (C) Recurrent vomiting (D) Excessive use of carbonic anhydrase inhibitors

Description : Metabolic alkalosis can occur in (A) Severe diarrhoea (B) Renal failure (C) Recurrent vomiting (D) Excessive use of carbonic anhydrase inhibitors

Last Answer : Answer : C

Which one of the following statements in regard to the excretion by the human kidneys is correct? (a) Descending limb of loop of Henle is impermeable to water.(b) Distal convoluted tubule is incapable of reabsorbing HCO3 – . (c) Nearly 99 per cent of the glomerular filtrate is reabsorbed by the renal tubules. (d) Ascending limb of loop of Henle is impermeable to electrolytes.

Description : Which one of the following statements in regard to the excretion by the human kidneys is correct? (a) Descending limb of loop of Henle is impermeable to water. (b) Distal convoluted tubule is ... reabsorbed by the renal tubules. (d) Ascending limb of loop of Henle is impermeable to electrolytes.

Last Answer : (c) Nearly 99 per cent of the glomerular filtrate is reabsorbed by the renal tubules.

Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow

Description : Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow

Last Answer : Answer : D

Phenolsulphonephthalein excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal blood low

Description : Phenolsulphonephthalein excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal blood low

Last Answer : Answer : D

One of the potent st imu lators of aldosterone secretion is (A) Increased sodium concentration (B) Decreased potassium concentration (C) Increased potassium concentration (D) Increased ECF volume

Description : One of the potent st imu lators of aldosterone secretion is (A) Increased sodium concentration (B) Decreased potassium concentration (C) Increased potassium concentration (D) Increased ECF volume

Last Answer : Answer : C

A 73 year old male presented with an acute attack of gout in his left knee. What is the most likely underlying metabolic cause? 1) decreased renal excretion of uric acid 2) endogenous overproduction of uric acid 3) excessive dietary purine intake 4) lactic acidosis 5) starvation

Description : A 73 year old male presented with an acute attack of gout in his left knee. What is the most likely underlying metabolic cause? 1) decreased renal excretion of uric acid 2) endogenous overproduction of uric acid 3) excessive dietary purine intake 4) lactic acidosis 5) starvation

Last Answer : Answers-1 The aetiology of gout can broadly be divided into cases where there is underexcretion of urate via the kidney (90%) or endogenous overproduction of uric acid (10%) although in practical ... diuretic use. Excessive dietary intake of purines is unlikely to be the main cause in this case.

Respiratory alkalosis can occur in (A) Bronchial asthma (B) Collapse of lungs (C) Hysterical hyperventilation (D) Bronchial obstruction

Description : Respiratory alkalosis can occur in (A) Bronchial asthma (B) Collapse of lungs (C) Hysterical hyperventilation (D) Bronchial obstruction

Last Answer : Answer : C

Salicylate poisoning can cause (A) Respiratory acidosis (B) Metabolic acidosis with normal anion gap (C) Metabolic acidosis with increased anion gap (D) Metabolic alkalosis

Description : Salicylate poisoning can cause (A) Respiratory acidosis (B) Metabolic acidosis with normal anion gap (C) Metabolic acidosis with increased anion gap (D) Metabolic alkalosis

Last Answer : Answer : C

Total CO2 is increased in (A) Respiratory acidosis (B) Metabolic alkalosis (C) Both respiratory acidosis and metabolic alkalosis (D) Respiratory alkalosis

Description : Total CO2 is increased in (A) Respiratory acidosis (B) Metabolic alkalosis (C) Both respiratory acidosis and metabolic alkalosis (D) Respiratory alkalosis

Last Answer : Answer : C

A 59-year-old trauma patient has suffered multiple septic complications including severe pneumonia, intraabdominal abscess, and major wound infection. He has now developed signs of multisystem organ failure. Which of the following statement(s) is/are true concerning necessary changes to be made in his nutritional management? a. Carbohydrate load should be reduced in the face of respiratory failure b. In patients with renal failure, protein intake should be diminished c. During hemodialysis protein intake should be limited to the same extent d. In patients with hepatic failure, carbohydrate load should be increased

Description : A 59-year-old trauma patient has suffered multiple septic complications including severe pneumonia, intraabdominal abscess, and major wound infection. He has now developed signs of multisystem organ ... the same extent d. In patients with hepatic failure, carbohydrate load should be increased

Last Answer : Answer: a, b The most severe complication of sepsis is multiple system organ dysfunction syndrome, which may result in death. The development of organ failure requires changes in the ... should be provided as fat emulsion. If encephalopathy develops, protein load should also be reduced0

Thiazide diuretics and furosemide have directionally opposite effect on the net renal excretion of the following substance: A. Uric acid B. Calcium C. Magnesium D. Bicarbonate

Description : Thiazide diuretics and furosemide have directionally opposite effect on the net renal excretion of the following substance: A. Uric acid B. Calcium C. Magnesium D. Bicarbonate

Last Answer : B. Calcium

Which of the following would help in prevention of diuresis? (a) More water reabsorption due to undersecretion of ADH. (b) Reabsorption of Na+ and water from renal tubules due to aldosterone. (c) Atrial natriuretic factor causes vasoconstriction. (d) Decrease in secretion of renin by JG cells. (NEE

Description : Which of the following would help in prevention of diuresis? (a) More water reabsorption due to undersecretion of ADH. (b) Reabsorption of Na+ and water from renal tubules due to ... Atrial natriuretic factor causes vasoconstriction. (d) Decrease in secretion of renin by JG cells. (NEE

Last Answer : (b) Reabsorption of Na+ and water from renal tubules due to aldosterone.

In the human kidney: a. renal plasma flow is normally 660 ml/minute b. blood flow in the cortex is greater than that in the medulla c. resorption of ions and water occurs mainly in the distal convoluted tubules d. anti-diuretic hormone increases water resorption mainly in the distal convoluted tubules

Description : In the human kidney: a. renal plasma flow is normally 660 ml/minute b. blood flow in the cortex is greater than that in the medulla c. resorption of ions and water ... the distal convoluted tubules d. anti-diuretic hormone increases water resorption mainly in the distal convoluted tubules

Last Answer : blood flow in the cortex is greater than that in the medulla

Thiazide diuretics inhibit (A) Carbonic anhydrase (B) Aldosterone secretion (C) ADH secretion (D) Sodium reabsorption in distal tubules

Description : Thiazide diuretics inhibit (A) Carbonic anhydrase (B) Aldosterone secretion (C) ADH secretion (D) Sodium reabsorption in distal tubules

Last Answer : Answer : D

Antidiuretic hormone (A) Is secreted by hypothalamus (B) Secretion is increased when osmolality of plasma decreases (C) Increases obligatory reabsorption of water (D) Acts on distal convoluted tubules and collecting ducts

Description : Antidiuretic hormone (A) Is secreted by hypothalamus (B) Secretion is increased when osmolality of plasma decreases (C) Increases obligatory reabsorption of water (D) Acts on distal convoluted tubules and collecting ducts

Last Answer : Answer : D

Select the option which shows correct matching of animal with its excretory organ and excretory product. Animal Excretory Excretory organ product (a) Labeo (Rohu) Nephridial Ammonia tubes (b) Salamander Kidneys Urea (c) Peacock Kidneys Urea (d) Housefly Renal tubules Uric acid

Description : Select the option which shows correct matching of animal with its excretory organ and excretory product. Animal Excretory Excretory organ product (a) Labeo (Rohu) Nephridial Ammonia tubes (b) Salamander Kidneys Urea (c) Peacock Kidneys Urea (d) Housefly Renal tubules Uric acid

Last Answer : (b) Salamander Kidneys Urea

Urine specific gravity of 1.054 indicates (A) Excellent renal function (B) Inappropriate secretion of ADH (C) Extreme dehydration (D) Presence of glucose or protein

Description : Urine specific gravity of 1.054 indicates (A) Excellent renal function (B) Inappropriate secretion of ADH (C) Extreme dehydration (D) Presence of glucose or protein

Last Answer : Answer : D

Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective 3) Increased Glomerular filtration rate is expected. 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+

Description : Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective ... 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+

Last Answer : Answers-2 H+ secretion, sodium reabsorption and ammonia production diminishes. RTA 4 is in effect hyporeninaemic hypoaldosteronism or failure of aldosterone action and thus helped treated with ... particularly. Aminoaciduria and increased urine bicarbonate are features of RTA types 1 and 2.

Measurement of inulin renal clearance is a measure for (A) Effective renal blood flow (B) Renal drug excretion rate (C) Active renal secretion (D) Glomerular filtration rate

Description : Measurement of inulin renal clearance is a measure for (A) Effective renal blood flow (B) Renal drug excretion rate (C) Active renal secretion (D) Glomerular filtration rate

Last Answer : (D) Glomerular filtration rate

Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function

Description : Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function

Last Answer : Answer : A

Mineralocorticoids increase the tubular secretion of (A) Sodium (B) Potassium (C) Chloride (D) Bicarbonate

Description : Mineralocorticoids increase the tubular secretion of (A) Sodium (B) Potassium (C) Chloride (D) Bicarbonate

Last Answer : Answer : B

The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis

Description : The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis

Last Answer : B

The conduction velocity of the nerve fibres is increased by: a. decreased temperature b. increased concentration of the external sodium ions e. increased axon diameter d. myelination

Description : The conduction velocity of the nerve fibres is increased by: a. decreased temperature b. increased concentration of the external sodium ions e. increased axon diameter d. myelination

Last Answer : myelination

. Vasodilatation occurs in: a. increased lactate concentration. b. decreased in skin c. increased hydrogen ions concentration d. increased in potassium concentration

Description : . Vasodilatation occurs in: a. increased lactate concentration. b. decreased in skin temperature c. increased hydrogen ions concentration d. increased in potassium concentration

Last Answer : increased in potassium concentration

In mammals, the primary function of the loop of Henle is: a) reabsorption of water b) water secretion c) ammonia secretion d) bicarbonate reabsorption

Description : In mammals, the primary function of the loop of Henle is: a) reabsorption of water b) water secretion c) ammonia secretion d) bicarbonate reabsorption

Last Answer : ANSWER: A -- REABSORPTION OF WATER

Which one of the following effects does not occur in salicylate intoxication ? (a) Hyperventilation (b) Hypothemia (c) Metabolic acidosis (d) Respiratory alkalosis (e) Tinnitus

Description : Which one of the following effects does not occur in salicylate intoxication ? (a) Hyperventilation (b) Hypothemia (c) Metabolic acidosis (d) Respiratory alkalosis (e) Tinnitus

Last Answer : Ans: B