Description : All the following features are found in blood chemistry in uncompensated lactic acidosis except (A) pH is decreased (B) Bicarbonate is decreased (C) pCO2 is normal (D) Anion gap is normal
Last Answer : Answer : D
Description : All the following changes in blood chemistry can occur in severe diarrhoea except (A) Decreased pH (B) Decreased bicarbonate (C) Increased pCO2 (D) Increased chloride WATER AND ELECTROLYTE BALANCE 287
Last Answer : Answer : C
Description : The primary event in respiratory alkalosis is (A) Rise in pH (B) Decrease in pCO2 (C) Increase in plasma bicarbonate (D) Decrease in plasma chloride
Last Answer : Answer : B
Description : Blood chemistry shows the following changes in compensated respiratory acidosis: (A) Increased pCO2 (B) Increased bicarbonate (C) Decreased chloride (D) All of these
Description : Plasma bicarbonate is increased in (A) Respiratory alkalosis (B) Metabolic alkalosis (C) Respiratory acidosis (D) Metabolic acidosis
Description : A young child presents with respiratory distress, worsening over 2 days. Blood gases show a pH of 7.25, a PCO2 of 7.5kPa, a PO2 of 8.5kPa, and a base excess of -4. Which of the ... required. 4) Results are consistent with late severe asthma. 5) Bicarbonate may be necessary to correct the acidosis.
Last Answer : Answers-4 In interpreting blood gas results, the following sequence may be useful: Inspect the pH: Is it low, normal or high? Inspect the CO2: Is it low, normal or high? Inspect the PO2: Is ... excess and normal pH. Bicarbonate is usually only considered if the base deficit exceeds about -8 or 00.
Description : Respiratory acidosis is that in which the blood pH is low due to increased retention of carbon dioxide caused by the lowering of the respiratory frequency or by pulmonary diseases that impair ... caused by metabolic disturbances that increase the concentration of bases (alkalis) in the blood.
Last Answer : Where are the chemoreceptors that detect the acidity of the blood and trigger the respiratory compensation located?
Description : A 45-year-old solicitor had an onset of severe, crushing, substernal chest pain while attending a football match. He collapsed on his way to the car. Bystander Cardiorespiratory Resuscitation ... His oxyhemoglobin curve is shifted to the left 5) His pulmonary artery pressure is probably elevated
Last Answer : Answers-5 This young patient with severe central chest pain has probably arrested due to myocardial infarction and arrhythmia. His gases reveal high PO2 following 100% O2 but severe acidosis ... no left to right shunting and high pulmonary pressures would be expected after this arrest scenario.
Description : During compensation of respiratory alkalosis, all the following changes occur except (A) Decreased secretion of hydrogen ions by renal tubules (B) Increased excretion of sodium in urine (C) Increased excretion of bicarbonate in urine (D) Increased excretion of ammonia in urine
Description : The initial event in respiratory acidosis is (A) Decrease in pH (B) Increase in pCO2 (C) Increase in plasma bicarbonate (D) Decrease in plasma bicarbonate
Description : Plasma bicarbonate is decreased in (A) Respiratory alkalosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Metabolic acidosis
Description : Salicylate poisoning can cause (A) Respiratory acidosis (B) Metabolic acidosis with normal anion gap (C) Metabolic acidosis with increased anion gap (D) Metabolic alkalosis
Description : Metabolic effects that generally attend antiinflammatory doses of aspirin include the following except: A. Increased CO2 production B. Hepatic glycogen depletion C. Metabolic acidosis D. Compensated respiratory alkalosis
Last Answer : C. Metabolic acidosis
Description : Metabolic alkalosis is characteristically found in which of the following? 1) An infusion of sodium chloride 2) Ileostomy 3) Mineralocorticoid deficiency 4) Pyloric stenosis 5) Salicylate poisoning
Last Answer : Answers-4 Pyloric stenosis is associated with vomiting and the loss of stomach content - hence a metabolic alkalosis. Mineralocorticoid excess (Conn's syndrome) is associated with a metabolic alkalosis. ... produce a metabolic acidosis. A sodium chloride infusion is neutral and does not alter pH.
Description : If the body undergoes alkalosis the respiratory center located in the medulla gets the information and induces the lowering of the respiratory frequency. The reduction of the respiratory frequency makes ... of bicarbonate towards the production of more hydrogen ions and thus the blood pH lowers.
Last Answer : What is the difference between respiratory acidosis and metabolic acidosis and what is the difference between respiratory alkalosis and metabolic alkalosis?
Description : Total CO2 is increased in (A) Respiratory acidosis (B) Metabolic alkalosis (C) Both respiratory acidosis and metabolic alkalosis (D) Respiratory alkalosis
Description : Which of the following statements about respiratory acidosis are true? A. Compensation occurs by a shift of chloride out of the red blood cells. B. Renal compensation occurs rapidly. C. Retention of ... of respiratory acidosis. E. The ratio of bicarbonate to carbonic acid is less than 20:1.
Last Answer : Answer: CE DISCUSSION: Renal compensation for acute hypoventilation is relatively slow. Depression of the respiratory center by morphine can lead to respiratory acidosis. Renal retention of bicarbonate, ... into red cells combine to increase the ratio of bicarbonate to carbonic acid to 20:1
Description : The toxicity spectrum of aspirin does not include (a) Increased risk of encephalopathy in children with viral infections (b) Increased risk of peptic ulcers (c) Hyperprothrombinemia (d) Metabolic acidosis (e) Respiratory alkalosis
Last Answer : Ans: C
Description : Respiratory alkalosis is caused by (A) An increase in carbonic acid fraction (B) A decrease in bicarbonic fraction (C) A decrease in the carbonic acid fraction (D) An increase in bicarbonate fraction
Description : Metabolic alkalosis can occur in (A) Severe diarrhoea (B) Renal failure (C) Recurrent vomiting (D) Excessive use of carbonic anhydrase inhibitors
Description : Hypercholremia is associated with (A) Hyponatremia (B) Hypernatremia (C) Metabolic alkalosis(D) Respiratory acidosis
Description : Salicylate poisoning in early stages causes (A) Metabolic acidosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Respiratory alkalosis
Description : Morphine poisoning causes (A) Metabolic acidosis (B) Respiratory acidosis (C) Metabolic alkalosis (D) Respiratory alkalosis
Description : Metabolic alkalosis occurs (A) As consequence of high intestinal obstruction (B) In central nervous system disease (C) In diarrhoea (D) In colitis
Last Answer : Answer : A
Description : Meningitis and encephalitis cause (A) Metabolic alkalosis (B) Respiratory alkalosis (C) Metabolic acidosis (D) Respiratory acidosis
Description : Acidosis is the condition in which the blood pH is abnormally low. Alkalosis is the condition in which the blood pH is abnormally high. Normal pH levels for the human blood are between 7.35 and 7.45 - slightly alkaline.
Last Answer : How does the breathing process correct acidosis?
Description : Hyperventilation: a. decreases cerebral blood flow b. increases ionized calcium concentration in the serum c. causes hypocapnia d. causes metabolic alkalosis
Last Answer : causes hypocapnia
Description : All the following statements about renal tubular acidosis are correct except (A) Renal tubules may be unable to reabsorb bicarbonate (B) Renal tubules may be unable to secrete hydrogen ions (C) Plasma chloride is elevated (D) Anion gap is decreased
Description : The pulmonary ventilation frequency (number of inhalations per time unit) rises or lowers the carbon dioxide concentration in blood. If it is intense the gas is more eliminated to the exterior and if it ... carbon dioxide and also of more hydrogen ions spending and the pH of the solution is raised.
Last Answer : What are acidosis and alkalosis?
Description : The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis
Last Answer : B
Description : Which one of the following effects does not occur in salicylate intoxication ? (a) Hyperventilation (b) Hypothemia (c) Metabolic acidosis (d) Respiratory alkalosis (e) Tinnitus
Last Answer : Ans: B
Description : At the pH of blood 7.4, the ratio between the carbonic acid and bicarbonate fractions is (A) 1 : 10 (B) 1 : 20 (C) 1 : 30 (D) 1 : 40
Description : Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective ... 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+
Last Answer : Answers-2 H+ secretion, sodium reabsorption and ammonia production diminishes. RTA 4 is in effect hyporeninaemic hypoaldosteronism or failure of aldosterone action and thus helped treated with ... particularly. Aminoaciduria and increased urine bicarbonate are features of RTA types 1 and 2.
Description : Active transport of a substance across biological membranes has the following characteristics except: A. It is specific B. It is pH dependent C. It is saturable D. It requires metabolic energy
Last Answer : B. It is pH dependent
Description : Which one of the following is a feature of the VIPoma syndrome? 1) Alkalosis 2) Hypoglycaemia 3) Hypokalaemia 4) Increased gastric acid seceretion 5) Provocation of VIP release by somatostatin
Last Answer : Answers-3 a, b,d,e: All opposite to what is expected. VIPOMA -Features vasoactive intestinal polypeptide secreting tumour, mainly pancreas rarely ganglioneuroblatoma (sympathetic ... -peripheral vasodilation - inhibits gastric acid secretion -potentiates acetylcholine action on salivary glands
Description : Anion gap is the difference in the plasma concentrations of (A) (Chloride) – (Bicarbonate) (B) (Sodium) – (Chloride) (C) (Sodium + Potassium) – (Chloride + Bicarbonate) (D) (Sum of cations) – (Sum of anions)
Description : Recurrent vomiting leads to loss of (A) Potassium (B) Chloride (C) Bicarbonate (D) All of these
Description : Chloride shift is (A) H ions leaving the RBC in exchange of Cl- (B) Cl– leaving the RBC in exchange of bicarbonate (C) Bicarbonate ion returns to plasma and exchanged with chloride which shifts into the cell (D) Carbonic acid to the plasma
Description : Mineralocorticoids increase the tubular secretion of (A) Sodium (B) Potassium (C) Chloride (D) Bicarbonate
Description : Concentration of the following is higher in intracellular fluid than in extracellular fluid: (A) Sodium (B) Potassium (C) Chloride (D) Bicarbonate
Description : The ion which activates salivary amylase activity is (A) Chloride (B) Bicarbonate (C) Sodium (D) Potassium
Description : At pH 7.4, the ratio of bicarbonate : dissolved CO2 is (A) 1 : 1 (B) 10 : 1 (C) 20 : 1 (D) 40 : 1
Description : The normal concentration of bicarbonate in blood is (A) 21 meq/L (B) 24 meq/L (C) 26 meq/L (D) 30 meq/L
Description : The ability of liver to remove a dye like BSP from the blood suggests a normal (A) Excretory function (B) Detoxification function (C) Metabolic function (D) Circulatory function
Description : In patients receiving massive blood transfusion for acute blood loss, which of the following is/are correct? A. Packed red blood cells and crystalloid solution should be infused to restore oxygen ... should be administered with every 5 units of packed red blood cells to avoid hypocalcemia.
Last Answer : Answer: A DISCUSSION: Patients who are suffering from acute blood loss require crystalloid resuscitation as the initial maneuver to restore intravascular volume and re-establish vital signs. If 2 to 3 liters ... when the infusion of blood proceeds at a rate exceeding 1 to 2 units every 5 minutes
Description : If the body experiences acidosis the respiratory center located in the medulla gets the information and induces the increase of the respiratory frequency. The increment of the respiratory frequency makes the ... of bicarbonate towards the spending of more hydrogen ions and thus the blood pH raises.
Last Answer : How does the breathing process correct alkalosis?
Description : Reduction in pH of blood will (a) decrease the affinity of haemoglobin with oxygen (b) release bicarbonate ions by the liver (c) reduce the rate of heartbeat (d) reduce the blood supply to the brain.
Last Answer : (a) decrease the affinity of haemoglobin with oxygen
Description : Which one of the following is NOT a function of kidney - (1) Regulation of blood pH (2) Removal of metabolic wastes from the body (3) Production of antibodies (4)Regulation of osmotic pressures of the blood
Last Answer : (3) Production of antibodies Explanation: Kidneys are essential in the urinary system and also serve homeostatic functions such as the regulation of electrolytes, maintenance of acid-base balance, and ... diverted to the urinary bladder whereas the antibodies are produced by antigens in the cell.