What are the factors that hinder regional integration?

What are the factors that hinder regional integration?
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1. Geography of region.2. Absence of common model or strategy for development.3. Differences in stages of growth and development.4. Competition for location of industries.5. Conflict between territorial and regional demands andloyalty.(Insularity)6. Absence if common currency.7. Unequal distributions of resources.8. Lack of diversification in productions.9. Influence of multi-national corporation.
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