1. It contains 1149 monographs and 123 appendices and available in two volumes.
2. Introduction of computer generated formula
3. Some titles have been changed to include more commonly accepted names in India
e.g.HyoscineHydrobromide for Scopolamine hydrobromide.
4. I.R and U.V absorption spectrophotometric tests for identification of drug substance have been introduced.
5. HPLC has been widely used as method of analysis in many formulations.
6. Test for bacterial endotoxins as a more suitable substitute for test for pyrogens.
7. Number of general monographs e.g. eye drops ,eye ointments pessaries have been included.
8. A quantitative method for determining particulate matter in injectable preparation has been replaced by qualitative test.
9. Biological assays provided for vaccines, hormones, blood products.
10. ORS-Citrate formula recommended by WHO introduced.