Write in detail about modified percolation process.

Write in detail about modified percolation process. 
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1 Answer

Answer :

Modified Percolation: In percolation process for tinctures drug\ percolate (d/p) ratio is 1:4.The drug/percolate ratio is reduced to 1:3 by modifying percolation process. Thus saves lot of heat, time and menstrum.

It is proved that the menstrum remaining in contact with the drug dissolves more active constituents than the flowing menstrum. Hence simple percolation process requires more menstrum to exhaust the drug. But if continuous percolation stage has suitable breaks by short maceration stages, the d/p ratio can be reduced to 1:3

e.g .In Simple Percolation process:

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After exhaustion of the drug, the percolate is evaporated and then mixed with main percolate.

 Final volume is made by adding more menstrum. 

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