That's a pretty big difference. If they were bees, which is unlikely, it would be best to call a beekeeper to dump the honeycomb with the queen and the remaining bees will fly away on their own. Wasps usually settle in the attic, then it is possible to destroy their nest at night when they are not flying. The hornets are much larger and are quite noisy during the flight. I have never seen you in the house, I have no idea how to deal with them ...