Point out incompatibility (if any) and describe suitable method for its dispense.

Point out incompatibility (if any) and describe suitable method for its dispense.
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1 Answer

Answer :

Rx
Quinine sulphate ………1.5 gm
Dilute sulphuric acid …..4ml
Potassium iodide ……….8gm
Water upto ……………200 ml
Prepare mixture, send ………100 ml
Dil. sulphuric acid is added to dissolve the quinine sulphate, but potassium iodide present in
formulation react with dil. sulphuric acid to form hydroiodic acid further it gets oxide to
form free iodine, now free iodine, hydroiodic acid and quinine sulphate together form
iodosulphide of quinine called “herapathite”
It form olive green scales after three days stay.
Correction:
1. Dispense it for three days.
2. Dispense in two different bottles one bottle containing dil. sulphuric acid with
quinine sulphate and in another bottle potassium iodide and water. Instruct the
patient to mix them before the dose actually taken.
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