Explain the term ‘Aseptic technique’

Explain the term ‘Aseptic technique’
by

1 Answer

Answer :

Definition: The method which is used to prevent the access of microorganism during the
preparation of parenteral product and their testing are called “Aseptic Technique”
 The entry of the personnel into the aseptic should be through air lock. To maintain
sterility
 Special trained person should be selected to work in sterile area
 They are required to wear sterile clothes and should be subjected to regular health
check up
 They should not be the carrier of infectious disease
 Ceiling walls and floor of aseptic area sealed and well painted
 Stainless steel counters should be fitted on the wall
 Mechanical equipment should be housed in stainless steel cabinet
 The air of aseptic area should be free from fibre, dust and micro organism
 The work has to be carried out under HEPA filter
 The air has to be supplied under positive pressure
 Ultra violet lamps are fitted in the area to maintain sterility
by

Related questions

Define the term prescription and list various errors seen in dispensing prescription

Description : Define the term prescription and list various errors seen in dispensing prescription

Last Answer : Prescription: Prescription is a written order given by registered medical practitioner, any other licensed person, veterinarians or dentist to pharmacist to dispense proper medication to patient. Common ... may cause synergism or antagonism. iii. Ex. Acetylcholine and Atropine produce antagonism.

List different test for identification of an emulsion & explain any one.

Description : List different test for identification of an emulsion & explain any one.

Last Answer : List different test for identification: 1) Dilution Test - 2) Dye Test- 3) Conductivity Test- 4)Fluorescence Test: 5)Cobalt Chloride Test: Explanation of any one. 1) Dilution Test -  Emulsion ... an emulsion and dried, it turns from blue to pink, indicating that the emulsion is o/w type.

Explain the formulation of parenteral preparation.

Description : Explain the formulation of parenteral preparation.

Last Answer : 1) Vehicles 2) Adjuvants  Solubilising agent  Stabilizers:  Buffering agents  Antibacterial agents:  Chelating agents:  Suspending,  Emulsifying and wetting agents:  Tonicity factors 1) ... other body fluids. The isotonicity of solution may be adjusted by adding Sodium chloride, dextrose etc

Define 'Incompatibility’. What is adjusted type of Incompatibility, explain with example.

Description : Define 'Incompatibility’. What is adjusted type of Incompatibility, explain with example.

Last Answer : Definition: Incompatibility occurs as a result of two or more antagonistic substances & an undesirable product is formed which may affect the safety, efficacy & appearance of the pharmaceutical preparation. ... citrate with half as much caffeine as that of caffeine citrate to form a clear mixture.

Explain LAL test

Description : Explain LAL test

Last Answer : LAL test is used for the detection and quantification of bacterial endotoxins: Limulus amebocyte lysate (LAL) is an aqueous extract of blood cells (amoebocytes) from the horseshoe crab, ... endotoxins, pH, temperature and presence of clotting enzyme system and clottable proteins from lysate.

Define dentifrices and explain formulation of it

Description : Define dentifrices and explain formulation of it

Last Answer : Dentifrices are the preparations meant to be applied to the teeth with a help of tooth brush for the purpose of cleaning the accessible surface of the teeth Abrasive agents:  The abrasive agents such as ... are added to improve the taste of the formulation.  Ex. Peppermint oil, cinnamon oil, etc.

Define ‘Shampoo’, and discuss the formulation of it.

Description : Define ‘Shampoo’, and discuss the formulation of it.

Last Answer : Shampoos are used as a preparation containing surface active agents which are used to remove dirt ,grease from the hair without affecting natural gloss of the hair and help to keep hair fragrant , ... - used to preserve the shampoo against bacteria or mould. e.g. Methyl Paraben, Propyl Paraben

Point out incompatibility (if any) and describe suitable method for its dispense.

Description : Point out incompatibility (if any) and describe suitable method for its dispense.

Last Answer : Rx Quinine sulphate 1.5 gm Dilute sulphuric acid ..4ml Potassium iodide .8gm Water upto 200 ml Prepare mixture, send 100 ml Dil. sulphuric acid is added to dissolve ... and in another bottle potassium iodide and water. Instruct the patient to mix them before the dose actually taken.

What is Dusting powder, Give classification of it mention the formulation ingredients of it.

Description : What is Dusting powder, Give classification of it mention the formulation ingredients of it.

Last Answer : Dusting powders are the powders meant for external application to the skin and are generally applied in a fine state of sub division to avoid local irritation. The dusting powders are used for antiseptic ... mixing of two or more ingredients; such as starch, talc, kaolin as they are chemically inert

Define parenteral. Give essential qualities of parenteral products .give the steps involved in manufacturing of parenteral products.

Description : Define parenteral. Give essential qualities of parenteral products .give the steps involved in manufacturing of parenteral products.

Last Answer : Definition of parenteral products Parenteral products are considered to be the sterile solutions, suspension or emulsions that are administrated by hypodermic injection either in the form in which ... containers.  Sterilisation.  Evaluation of parenteral preparations.  Labelling and packaging.

Define (i)Nasal drops

Description : Define (i)Nasal drops

Last Answer : Nasal drops are aqueous solutions for instilling into nose with dropper torelieve congestion ,inflammation & to combat infection (ii)Inhalation: These are liquid preparation consisting of volatile substances and ... with a dropper for cleaning of ear, softening of wax and for treating mild infection

Define 'Pyrogen'. Name the different methods of Pyrogen testing. Describe Rabbits method.

Description : Define 'Pyrogen'. Name the different methods of Pyrogen testing. Describe Rabbits method.

Last Answer : Definition: Pyrogens are by-product of bacterial metabolism, pyrogens are polysaccharides, thermostable, soluble in water, unaffected by bactericide and can pass through bacterial proof filters Different methods of Pyrogen ... 0.6 °C or and sum of group maximum temp rises doesn't exceed 3.7°c.

What is the principle behind sterility testing? Describe Membrane filtration method for sterility testing.

Description : What is the principle behind sterility testing? Describe Membrane filtration method for sterility testing.

Last Answer : Principle: Basic principle of sterility test is that if bacteria or fungi are placed in a medium which provides the nutritive material and water and kept at favourable temperature the organism will grow and their presence can be indicated by the turbidity in the clear medium.

Calculate the displacement value of zinc oxide from following data

Description : Calculate the displacement value of zinc oxide from following data

Last Answer : i) Capacity of mould = 15 grain ii) Wt. of 6 unmedicated suppositories = 90 grain iii) Wt. of six suppositories containing 40% zinc oxide = 132 grain. Note: student may use grain value as 65 mg and ... Medicament Amount of base without drug - actual amount base 3.4212 / 0.7002 = 4.886 = Approx.5

What are 'Syrups'? Give different methods of preparation of syrup.

Description : What are 'Syrups'? Give different methods of preparation of syrup.

Last Answer : Syrup: Syrup is sweet, viscous, concentrated or nearly saturated aqueous solution of sucrose containing 66.7%w/w of sugar. Methods of preparation of syrup. 1. Simple solution method 2. By ... after the reaction is complete add sucrose and flavouring agent than adjust the volume with purified water.

Define 'Gargles' & 'Mouth Wash'. What are the uses of douches? Discuss with example.

Description : Define 'Gargles' & 'Mouth Wash'. What are the uses of douches? Discuss with example.

Last Answer : Gargle: Gargles are aqueous solutions to prevent & treat throat infections & are used to relieve soreness in mild throat infections. Mouthwash: Mouth washes are aqueous solutions with pleasant taste and odour used to ... lacticacid (0.5 to 2%),Chlorohexidine ( 0.002%) 3) Astringent e.g.alum(1%),

What is 'Cracking of emulsion'? Describe any four factors responsible for cracking of emulsion

Description : What is 'Cracking of emulsion'? Describe any four factors responsible for cracking of emulsion

Last Answer : 'Cracking of emulsion': Cracking means the separation of two layers of dispersed phase and continuous phase, due to the coalescence of dispersed phase globules which are difficult to redisperse by shaking ... emulsion. So it is necessary to take steps to retard creaming as far as possible.

Define mixture. Describe method of dispensing mixture containing diffusible solids.

Description : Define mixture. Describe method of dispensing mixture containing diffusible solids.

Last Answer : Definition: Mixture is a liquid dosage form containing medicament or medicaments are dissolved, disperse and suspended in the given vehicle. Method of dispensing:  Finely powder the drug in a mortar. Add ... cork, label and dispense.  Apply the secondary label Shake the bottle well before use .

Write a short note on formulation and method of preparation of 'Effervescent granules'.

Description : Write a short note on formulation and method of preparation of 'Effervescent granules'.

Last Answer : Formulation :These are solid dosage form of medicament, meant for internal use.  These are composed of citric acid, tartaric acid & sodium bicarbonate.  In presence of water, acid reacts with alkali ... to break the lumps which may be formed during drying. iv) Then packed in air tight containers.

What is indiffusible mixture; Give composition of compound tragacanth powder, mention the example of indiffusible mixture.

Description : What is indiffusible mixture; Give composition of compound tragacanth powder, mention the example of indiffusible mixture.

Last Answer : Indiffusible mixture are those mixture which contain indiffusible solids, solids are not soluble in water they do not remain suspended for long time after shaking therefore to maintain their stability suspending agent are added, the ... .25 gm Simple syrup 15 ml Water .upto .90 ml

Write four advantages of suppositories

Description : Write four advantages of suppositories

Last Answer : Advantages of suppositories  These can be easily administered to children, old persons & to unconscious patients.  These are inserted into body cavity to produce local effect of the medicament ... slowly absorbed giving sustained action.  They are also been used for prolongation of drug action

What is physical incompatibility? Give one example

Description : What is physical incompatibility? Give one example

Last Answer : When two or more than two substances are combined together, a physical change takes place and an unacceptable product is formed. Physical incompatibility is usually due to immiscibility, insolubility, ... Light magnesium carbonate ---- 60g. Send five powders The combination forms eutectic mixture.

What are the precautions taken during storage of eye drops

Description : What are the precautions taken during storage of eye drops

Last Answer : Following precautions taken during storage of eye drops: i. If the dropper is separate, always hold it with its tip down. ii. Never touch the surface of dropper iii. Never rinse the dropper iv. Never ... color v. When the dropper is at the top of the bottle, avoid contaminating the cap when removed

Why white paraffin is used in eye ointment

Description : Why white paraffin is used in eye ointment

Last Answer : White soft paraffin is prepared by bleaching yellow soft paraffin. Some of the bleaching agent may remain sticking to the base even after careful washing. Which when used in the eye may lead to irritation.

What is aseptic technique? List the various sources of contamination and explain the sterility test.

Description : What is aseptic technique? List the various sources of contamination and explain the sterility test.

Last Answer : Aseptic technique:  The method which is used to prevent the access of microorganism during the preparation of parenteral product and their testing are called Aseptic Technique . Sources of contamination: 1) ... the sample is declared to have pass the test and same test is repeated for two times.

Which of the following terms best fits the destruction of all living micobes, spores and viruses. a. Sanitization b. Sterilization c. Aseptic Technique d. Pasteurization

Description : Which of the following terms best fits the destruction of all living micobes, spores and viruses. a. Sanitization b. Sterilization c. Aseptic Technique d. Pasteurization

Last Answer : b. Sterilization

one way to get a pure culture is by using _____. a. Aseptic technique b. Pour-plate method c. Streak-plate method d. A and C e. B and C

Description : one way to get a pure culture is by using _____. a. Aseptic technique b. Pour-plate method c. Streak-plate method d. A and C e. B and C

Last Answer : d. A and C

What is aseptic technique? State its importance.

Description : What is aseptic technique? State its importance.

Last Answer : Definition: Aseptic technique  The method which is used to prevent the access of microorganism during the preparation of parenteral product and their testing are called Aseptic Technique . Importance ... be maintained. 7. It helps to maintain required environment for testing of sterile products.

Explain the term aseptic techniques. What are the various points to be considered while designing an aseptic room?

Description : Explain the term aseptic techniques. What are the various points to be considered while designing an aseptic room?

Last Answer : Definition: The method which is used to prevent the access of microorganism during the preparation of parenteral product and their testing are called aseptic Technique . Design of aseptic room: 1. Site: ... connection. Vacuum. Disposable waste. 6. Furniture: Shack type. Fume -cupboard.

When Performing medical aseptic hand washing the hands should be positioned?

Description : When Performing medical aseptic hand washing the hands should be positioned?

Last Answer : In medical you are to wash hand very often. When washing thehands you should wash them with soap from the top to thebottom.

In 1842, Edwin Chadwick's report raised the possibility that sewage spreads disease along with a ______ outbreak which began the ________ movement. a. typhoid, aseptic b. cholera, sanitation c. polio, immunization d. none of the above are correct

Description : In 1842, Edwin Chadwick's report raised the possibility that sewage spreads disease along with a ______ outbreak which began the ________ movement. a. typhoid, aseptic b. cholera, sanitation c. polio, immunization d. none of the above are correct

Last Answer : b. cholera, sanitation

The virus(es) which can cause aseptic meningitis is/are A.Polioviruses B.Coxsackieviruses C.Echo viruses D.All of these

Description : The virus(es) which can cause aseptic meningitis is/are A.Polioviruses B.Coxsackieviruses C.Echo viruses D.All of these

Last Answer : D.All of these

Class 100 area is referred to (A) Manufacturing area (B) Aseptic area (C) Clean room (D) Ware house

Description : Class 100 area is referred to (A) Manufacturing area (B) Aseptic area (C) Clean room (D) Ware house

Last Answer : (B) Aseptic area

Define aseptic techniques. What are the various sources of contamination?

Description : Define aseptic techniques. What are the various sources of contamination?

Last Answer : Definition: Aseptic technique  The method which is used to prevent the access of microorganism during the preparation of parenteral product and their testing are called Aseptic Technique Sources of ... are also a source of contamination. A handkerchief is the richest source of contamination. 

Give any four precautions to be taken during aseptic work.

Description : Give any four precautions to be taken during aseptic work.

Last Answer : i. Self hygiene: avoid coughing, sneezing.  ii. Avoid contamination of products.  iii. Cover the whole body by Wear complete body suit up to foot.  iv. Wear hand gloves.  v. Allow minimum persons to work in aseptic area.  vi. Don’t touch unnecessarily.

Which of the following statement(s) concerning intravenous nutritional support is/are true? a. Concentrations of glucose no higher than 5% should be used to avoid peripheral vein sclerosis b. A major disadvantage of the peripheral technique is limited caloric delivery c. If total parenteral nutrition is required, access to the superior vena cava via the external jugular vein is the most suitable site d. Venous thrombosis is an uncommon complication for long-term central vein catheterization

Description : Which of the following statement(s) concerning intravenous nutritional support is/are true? a. Concentrations of glucose no higher than 5% should be used to avoid peripheral vein sclerosis ... suitable site d. Venous thrombosis is an uncommon complication for long-term central vein catheterization

Last Answer : Answer: b Although peripheral access can be used for intravenous nutrition, the major disadvantage of this technique is limited caloric delivery to meet catabolic demands within tolerated fluid ... studies that use phlebography or radionucleotide venography indicate the incidence is as high as 35%

All of the following are true regarding the Qualitative Risk Analysis process except which one? A. Probability and impact and expert interview are used to help correct biases that occC. Qualitative Risk Analysis is an easy method of determining risk probability and impact that usually takes a good deal of time to perform. D. Risk urgency assessment is a tool and technique of this process used to determine which risks need near-term response plans.ur in the data you’ve gathered during this process. B. The probability and impact matrix is used during this process to assign red, yellow, and green conditions to risks.

Description : All of the following are true regarding the Qualitative Risk Analysis process except  which one?  A. Probability and impact and expert interview are used to help correct biases that occur  in the data ... of this process used to determine  which risks need near-term response plans.

Last Answer : C. Qualitative Risk Analysis is an easy method of determining risk probability and  impact that usually takes a good deal of time to perform.

PNDT Full form [A] Pre-Natal Diagnostic Technique [B] Person Not Developed Term [C] Post National Democratic Tenure [D] None of the above

Description : PNDT Full form [A] Pre-Natal Diagnostic Technique [B] Person Not Developed Term [C] Post National Democratic Tenure [D] None of the above

Last Answer : [A] Pre-Natal Diagnostic Technique

M-Commerce is a new term in latest marketing technique. It is _______________ 1. Misuse of Mobile phones & E-commerce 2. Mobile phones in marketing 3. Marketing by Commerce Students 4. Mega Commercial activities 5. None of these

Description : M-Commerce is a new term in latest marketing technique. It is _______________ 1. Misuse of Mobile phones & E-commerce 2. Mobile phones in marketing 3. Marketing by Commerce Students 4. Mega Commercial activities 5. None of these

Last Answer : Misuse of Mobile phones & E-commerce

The term ‘Hitch hiking’ is related to which technique. (a) Peer tutoring (b) Debate (c) Seminar (d) Brain storming

Description : The term ‘Hitch hiking’ is related to which technique. (a) Peer tutoring (b) Debate (c) Seminar (d) Brain storming

Last Answer : (d) Brain storming