Description : The elderly patients are relatively intolerant to: A. Digoxin B. Salbutamol C. Propranolol D. Nifedipine
Last Answer : A. Digoxin
Description : In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil
Last Answer : B. Digoxin
Description : Select the drug which can impair carbohydrate tolerance in prediabetics but prolongs insulin hypoglycaemia: A. Salbutamol B. Propranolol C. Prazosin D. Nifedipine
Last Answer : B. Propranolol
Description : In congestive heart failure patients: A. Volume of distribution of all drugs is increased B. Hepatic clearance of drugs is unaffected C. Orally administered diuretics may not be effective, but the same may work parenterally D. Inotropic action of digoxin is attenuated
Last Answer : C. Orally administered diuretics may not be effective, but the same may work parenterally
Description : Which adverse drug effect is more common in children than in adults: A. Isoniazid induced neuropathy B. Chlorpromazine induced muscle dystonia C. Digoxin induced cardiac arrhythmia D. Penicillin hypersensitivity
Last Answer : B. Chlorpromazine induced muscle dystonia
Description : A drug which is generally administered in standard doses without the need for dose individualization is: A. Insulin B. Mebendazole C. Prednisolone D. Digoxin
Last Answer : B. Mebendazole
Description : Select the drug that undergoes extensive first-pass metabolism in the liver: A. Phenobarbitone B. Propranolol C. Phenylbutazone D. Theophylline
Description : Which of the following tocolytics used for suppressing labour is most likely to compromise placental perfusion: A. Salbutamol B. Ethyl alcohol C. Magnesium sulfate D. Nifedipine
Last Answer : D. Nifedipine
Description : Which of the following is a relatively cerebroselective anticholinesterase found to afford symptomatic improvement in Alzheimer's disease: A. Donepezil B. Gemfibrozil C. Pyridostigmine D. Pyritinol
Last Answer : A. Donepezil
Description : Which of the following cardiovascular agents is classified chemically as a glycoside? (a) Nifedipine (b) Digoxin (c) Flecainide (d) Cholestyramine (e) Warfarin
Last Answer : Ans: B
Description : Propranolol should not be prescribed for a patient of angina pectoris who is already receiving (a) Nifedipine (b) Felodipine (c) Verapamil (d) Isosorbide mononitrate
Last Answer : Ans: C
Description : Maximal medical therapy for treating angina pectoris is represented by which of the following choices? (a) Diltiazem, verapamil, nitroglycerin (b) Atenolol, isoproterenol, diltiazem (c) Verapamil, nifedipine, propranolol (d) Isosorbide, atenolol, diltiazem (e) Nitroglycerin, isosorbide, atenolol
Last Answer : Ans: D
Description : Which of the following agents used in prinzmetal’s angina has spasmolytic actions, which increase coronary blood supply? (a) Nitroglycerin (b) Nifedipine (c) Timolol (d) Isosorbide mononitrate (e) Propranolol
Description : A treatment of angina that consistently decreases the heart rate and can prevent vasospastic angina attacks is (a) Isosorbide dinitrate (b) NIFedipine (c) Nitroglycerin (d) Propranolol (e) Verapamil
Last Answer : Ans: E
Description : Propranolol should not be prescribed for a patient of angina pectoris who is already receiving: A. Nifedipine B. Felodipine C. Verapamil D. Isosorbide mononitrate
Last Answer : C. Verapami
Description : The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level
Last Answer : A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened
Description : In patients of hepatic cirrhosis: A. The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B. High doses of furosemide can be safely used C. Metformin is the preferred oral hypoglycaemic D. Disposition of atenolol is not significantly affected
Last Answer : D. Disposition of atenolol is not significantly affected
Description : Timolol eye drops are preferred over pilocarpine eye drops by glaucoma patients because: A. Timolol is more effective than pilocarpine B. Timolol acts by enhancing uveo-scleral outflow C. Timolol produces less ocular side effects D. There are no contraindications to timolol
Last Answer : C. Timolol produces less ocular side effects
Description : Which of the following is true of ‘placebos’: A. Placebo is a dummy medication B. Placebo is the inert material added to the drug for making tablets C. Placebos do not produce any effect D. All patients respond to placebos
Last Answer : A. Placebo is a dummy medication
Description : Which of the following drugs is preferred for termination of paroxysmal supraventricular tachycardia (a) Digoxin (b) Quinidine (c) Propranolol (d) Verapamil
Description : Which one of the following drugs predictably prolongs the PR interval and increases cardiac contractility? (a) Digoxin (b) Lidocaine (c) Propranolol (d) Quinidine (e) Verapamil
Last Answer : Ans: A
Description : The following drug terminates paroxysmal supraventricular tachycardia rapidly, but cannot be used to prevent its recurrences: A. Verapamil B. Adenosine C. Propranolol D. Digoxin
Last Answer : B. Adenosine
Description : The following drug is preferred for termination as well as prophylaxis of paroxysmal supraventricular tachycardia: A. Digoxin B. Verapamil C. Propranolol D. Quinidine
Last Answer : B. Verapami
Description : The following drug has been found to improve urine flow in elderly males with benign prostatic hypertrophy: A. Nifedipine B. Prazosin C. Disopyramide D. Imipramine
Last Answer : B. Prazosin
Description : he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to ... release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori
Last Answer : B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect
Description : The distinctive feature of nimesulide is: A. It does not inhibit prostaglandin synthesis B. It does not cause gastric irritation C. It is usually well tolerated by aspirin intolerant asthma patients D. It is not bound to plasma proteins
Last Answer : C. It is usually well tolerated by aspirin intolerant asthma patients
Description : What is true of nimesulide: A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B. It is preferred for long-term use in rheumatoid arthritis C. It is contraindicated in aspirin intolerant asthma patients D. All of the above
Last Answer : A. It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition
Description : if you suspect atrial flutter : Consider digoxin if not already in use because it frequently increases the conduction ratio and decreases the ventricular rate. , Avoid adrenergic and ... to the muscle decrease blood supply to the muscle the heart trying to beat fast ______________________________
Last Answer : decrease O2 supply to the muscle
Description : Shortacting nifedipine formulation is not recommended now for treatment of hypertension because: A. It tends to increase heart rate and cardiac work B. It invokes pronounced reflex sympathetic discharges C. It can impair haemodynamics in patients with diastolic dysfunction D. All of the above
Last Answer : D. All of the above
Description : The following calcium channel blocker should not be used in patients with ischaemic heart disease: A. Verapamil sustained release tablet B. Amlodipine tablet C. Nifedipine soft geletin capsule D. Nifedipine extended release tablet
Last Answer : C. Nifedipine soft geletin capsule
Description : Digoxin given for cardiac failure is extremely valuable in patients of (a) Thyrotoxicosis (b) Beriberi (c) Cor pulmonale (d) Atrial fibrillation
Description : The most effective drug for prevention of stroke in atrial fibrillation patients is: A. Aspirin B. Warfarin C. Low dose subcutaneous heparin D. Digoxin
Last Answer : B. Warfarin
Description : Long-term maintenance therapy with digoxin is the best option in the following category of CHF patients: A. Hypertensive patients B. Patients with hypertrophic cardiomyopathy C. Patients with associated atrial fibrillation D. Patients having cardiac valvular defects
Last Answer : C. Patients with associated atrial fibrillation
Description : Digoxin affords the following benefit/benefits in CHF: A. Restores cardiac compensation and relieves symptoms B. Reverses the pathological changes of CHF C. Prolongs survival of CHF patients D. Both ‘A’ and ‘B’ are correc
Last Answer : A. Restores cardiac compensation and relieves symptoms
Description : Digoxin is contraindicated in: A. Angina pectoris patients B. Ventricular tachycardia C. Hypertensive patients D. Complete heart-block
Last Answer : B. Ventricular tachycardia
Description : The following drug has been demonstrated to retard progression of left ventricular dysfunction and prolong survival of congestive heart failure patients: A. Digoxin B. Furosemide C. Enalapril D. Amrinone
Last Answer : C. Enalapril
Description : Propranolol is used in hyperthyroidism: A. As short-term symptomatic therapy till effect of carbimazole develops B. As long-term therapy after subtotal thyroidectomy C. In patients not responding to carbimazole D. To potentiate the effect of radioactive iodine
Last Answer : A. As short-term symptomatic therapy till effect of carbimazole develops
Description : Reflex bronchoconstriction is most likely to occur with the following form of inhaled antiasthma medication: A. Metered dose spray of drug in solution B. Dry powder rotacap C. Nebuliser D. Nebuliser with spacer
Last Answer : B. Dry powder rotacap
Description : Select the drug which has been found to be a strong human teratogen: A. Isoniazid B. Isotretinoin C. Hydralazine D. Propylthiouracil
Last Answer : B. Isotretinoin
Description : The following is a proven human teratogen: A. Chloroquine B. Warfarin sodium C. Dicyclomine D. Methyldopa
Last Answer : B. Warfarin sodium
Description : The most vulnerable period of pregnancy for the causation of foetal malformations due to drugs is: A. 18-55 days of gestation B. 56-84 days of gestation C. Second trimester D. 36 weeks onwards
Last Answer : A. 18-55 days of gestation
Description : Adverse consequences may follow sudden discontinuation of the following drug after chronic intake: A. Cocaine B. Cannabis C. Clonidine D. All of the above
Last Answer : C. Clonidine
Description : An addicting drug which produces little or no physical dependence is: A. Diazepam B. Phenobarbitone C. Amphetamine D. Methadone
Last Answer : C. Amphetamine