Description : The cardiac muscarinic receptors (a) Are of the M1 subtype (b) Are of the M2 subtype (c) Are selectively blocked by pirenzepine (d) Function through the PIP2 ? IP3/DAG pathway
Last Answer : Ans: B
Description : The cardiac muscarinic receptors: A. Are of the M1 subtype B. Are of the M2 subtype C. Are selectively blocked by pirenzepine D. Function through the PIP2 → IP3/DAG pathway
Last Answer : B. Are of the M2 subtype
Description : Muscarinic cholinergic receptors (a) Are located only on parasympathetically innervated effector cells (b) Mediate responses by opening an instrinsic Na+ ion channel (c) Are present on vascular endothelium which has no cholinergic nerve supply (d) Predominate in the autonomic ganglia
Last Answer : Ans: C
Description : Which of the following best describes the mechanism of action of scopolamine ? (a) Irreversible antagonist at nicotinic receptors (b) Irreversible antagonist at muscarinic receptors (c) ... receptors (d) Reversible antagonist at muscarinic receptors (e) Reversible antagonist at nicotinic receptors
Last Answer : Ans: D
Description : The following are true about the muscarinic receptors: a. they are found at the postganglionic parasympathetic synapses b. they can be selectively blocked by atropine c. M1 muscarinic receptors are found in the brain d. all above
Last Answer : all above
Description : Activation of the following type of receptors present on myenteric neurones by metoclopramide is primarily responsible for enhanced acetylcholine release improving gastric motility: A. Muscarinic M1 B. Serotonergic 5-HT3 C. Serotonergic 5-HT4 D. Dopaminergic D2
Last Answer : C. Serotonergic 5-HT4
Description : a1 – receptors are coupled with _______ G protein. (a) Gs (b) Gi (c) Gq (d) Go
Description : Reserprine, an alkaloid derived from the root of Rauwolfia serpentina (a) Can be used to control hyperglycemia (b) Can cause severe depression of mood (c) Can decrease gastrointestinal secretion and motility (d) Has no cardiac effects (e) A spare receptor agonist
Description : Which of the following is the most liquid money? A. M1 B. M2 C. Securities D. M3 E. Call Money
Last Answer : A. M1 Explanation: The most liquid portions of the money supply are measured by M1 because it contains currency and assets that can be converted to cash quickly. ―Near money‖ and ―near, near money,‖ which fall under M2 and M3, cannot be converted to currency as quickly.
Description : Consider different activities related to email: m1: Send an email from a mail client to a mail server m2: Download an email from mailbox server to a mail client m3: Checking email in a web browser Which is the application ... FTP m3: HTTP c. m1: SMTP m2: POP m3: HTTP d. m1: POP m2: SMTP m3: IMAP
Last Answer : c. m1: SMTP m2: POP m3: HTTP
Description : Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It ... used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation
Last Answer : A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms
Description : Initial bradycardia caused by intramuscular injection of atropine is believed to be caused by: A. Stimulation of medullary vagal centre B. Stimulation of vagal ganglia C. Blockade of M2 receptors on SA nodal cells D. Blockade of muscarinic autoreceptors on vagal nerve endings
Last Answer : D. Blockade of muscarinic autoreceptors on vagal nerve endings
Description : Postural hypotension is a common adverse effect of which one of the following types of drugs ? (a) ACE inhibitors (b) Alpha-receptor blockers (c) Arteriolar dilators (d) ß1 – selective receptor blockers (e) Nonselective ß - blockers
Description : Your patient is to receive a selective ß2 stimulant drug ß2 selective stimulant are often effective in (a) Angina due to coronary insufficiency (b) Asthma (c) Chronic heart failure (d) Delayed or insufficiently strong labor (e) All of the above
Description : Phenylephrine (a) Mimics the transmitter at post-synaptic receptors (b) Displaces transmitter from axonal terminal (c) Inhibits synthesis of transmitter (d) None of the above
Last Answer : Ans: A
Description : Dobutamine differs from dopamine in that (a) It does not activate peripheral dopaminergic receptors (b) It does not activate adrenergic ß receptors (c) It causes pronounced tachycardia (d) It has good blood-brain barrier penetrability
Description : a2–adrenergic receptors are associated with following except (a) Increase in phospholipase C activity (b) Increase in potassium channel conductance (c) Decrease in calcium channel conductance (d) Increase in adenylyl cyclase activity
Description : Yohimbine is an antagonist of ______ receptors. (a) a1 (b) a2 (c) both (a) and (b) (d) None of the above
Description : Characteristics of Vitamin D and its metabolites include which one of the following? (a) Act to decrease serum levels of calcium (b) Activation of their Vitamin D receptors increases cellular CAMP ... Vitamin D increase renal excretion of calcium (e) Vitamin D deficiency results in Pager's disease
Description : Following is an antagonist of ganglion type nicotinic receptors (a) Tubercurarine (b) a-bungarotoxin (c) Trimethaphan (d) All of the above
Description : Which of the following is a vasodilator drug used for hypertension that lacks a direct effect on autonomic receptors but may provoke anginal attacks? (a) Amyl nitrite (b) Hydralazine (c) Isosorbide mononitrate (d) Nifedipine (e) Nimodipine
Description : Denervation super-sensitivity includes (a) Proliferation of receptors (b) Loss of mechanism for transmitter removal (c) Increased post-junctional responsiveness (d) All of the above
Description : In male sex organs _______ system is responsible for erection. (a) Sympathetic (b) Parasympathetic (c) Norepinephrine (d) None of the above
Description : The units of moment of inertia of an area are a.kg - m b.m4 c.kg - m4 d.kg - m3 e.(kg - m)2
Last Answer : b. m4
Description : In the terminology of economics and money demand, the terms M3 and M4 are also known as : a) Short money b) Long money c) Broad money d) Narrow money
Last Answer : c) Broad money
Description : The units of moment of inertia are a.kgm4 b.kg-m2 c.kg/m2 d.kg/m e.m4
Last Answer : c. kg/m2
Description : In SI units, thermal conductivity is expressed in (A) Watt/m.°K (B) Watt/m2 . °K (C) Watt/m2 . °K (D) Watt/m4 . °K
Last Answer : (A) Watt/m.°K
Description : S.I. unit of Magnetic flux is (1) weber (2) weber/m (3) weber/m4 (4) weber–m2
Last Answer : weber
Description : Cisapride enhances gastrointestinal motility by: A. Activating serotonin 5-HT4 receptor B. Activating muscarinic M3 receptor C. Blocking dopamine D2 receptor D. All of the above
Last Answer : A. Activating serotonin 5-HT4 receptor
Description : Why is F=G M1 M2 /d^2?
Last Answer : F is force and it is equal to the gravitational constant times the mass of the first object times the mass of the second object divided by the distance between the two squared.
Description : ) In the terminology of economics and money demand, the terms M1 and M2 are also known as : a) Short money b) Long money c) Broad money d) Narrow money
Last Answer : d) Narrow money
Description : m1 and m2 are the members of two individual simple trusses of a compound truss. The compound truss will be rigid and determinate if (A) m = m1 + m2 (B) m = m1 + m2 + 1 (C) m = m1 + m2 + 2 (D) m = m1 + m2 + 3
Last Answer : (D) m = m1 + m2 + 3
Description : If RBI sucks excess money into circulation this will effect (a) M1 ; (b) M2 ; (c) Both ; (d) None
Last Answer : ; (c) Both ;
Description : Two point masses, M1 and M2, are 14 centimeters apart. M1 has a mass of 2 grams. M2 has a mass of 5 grams. Locate the center-of-mass of this system. w) 4 cm from M1 x) 4 cm from M2 y) 5 cm from M2 z) 7 cm from M1
Last Answer : ANSWER: X -- 4 CM FROM M2
Description : The inertia constants of two groups of machines which do not swing together are M1 and M2. The equivalent inertia constant of the system is
Last Answer : The inertia constants of two groups of machines which do not swing together are M1 and M2. The equivalent inertia constant of the system is M1M2/M1+M2
Description : Norepinephrine binds mainly to (A) α-Adrenergic receptors (B) β-Adrenergic receptrors (C) Muscarinic receptors (D) Nicotinic receptors
Last Answer : Answer : A
Description : The following are true about acetylcholine receptors: a. receptors at all autonomic ganglia are nicotinic b. receptors at the skeletal neuromuscular junction are muscarinic c. ... atropine d. acetylcholine receptors in the neuromuscular junction can be selectively blocked by tubocurarine
Last Answer : acetylcholine receptors in the neuromuscular junction can be selectively blocked by tubocurarine
Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors
Last Answer : B. It is longer acting
Description : Muscarinic cholinergic receptors: A. Are located only on parasympathetically innervated effector cells B. Mediate responses by opening an intrinsic Na+ ion channel C. Are present on vascular endothelium which has no cholinergic nerve supply D. Predominate in the autonomic ganglia
Last Answer : C. Are present on vascular endothelium which has no cholinergic nerve supply
Description : Which of the following is a very longacting ß2 – selective agonist that is used for asthma prophylaxis? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Salmeterol
Last Answer : Ans: E
Description : Select the correct statement about salmeterol. (a) It is a long acting selective ß2 agonist bronchodilator (b) It is a bronchodilator with anti-inflammatory property (c) It is a ß blocker that can be safely given to asthmatics (d) It is an antihistaminic with mast cells stabilizing property
Description : Desmopressin is preferred over arginine vasopressin in the treatment of diabetes insipidus for the following reasons except: A. It is a more potent antidiuretic B. It is a selective vasopressin V1 receptor agonist C. It has little vasoconstrictor activity D. It is longer acting
Last Answer : B. It is a selective vasopressin V1 receptor agonist
Description : Which of the following peptides is a selective vasopressin V2 receptor agonist: A. Arginine vasopressin B. Desmopressin C. Lypessin D. Terlipressin
Last Answer : B. Desmopressin
Description : Losartan is a: A. Selective AT1 receptor antagonist B. Selective AT2 receptor antagonist C. Nonselective AT1 + AT2 receptor antagonist D. AT1 receptor partial agonist
Last Answer : A. Selective AT1 receptor antagonist
Description : Which of the following is a selective H1 receptor agonist: A. 4-methyl histamine B. Impromidine C. 2-Thiazolyl ethylamine D. Chlorpheniramine
Last Answer : C. 2-Thiazolyl ethylamine